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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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February 2013 Volume 5 Issue 2

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Case Report

Rapidly evolving asymptomatic eosinophilia in a patient with lung adenocarcinoma causes cognitive disturbance and respiratory insufficiency: Case report

  • Authors:
    • Cheng-Hsiang Lo
    • Yee-Min Jen
    • Wen-Chiuan Tsai
    • Ping-Ying Chung
    • Woei-Yau Kao
  • View Affiliations / Copyright

    Affiliations: Department of Radiation Oncology, Tri-Service General Hospital, National Defense Medical Center, Taiwan, R.O.C, Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taiwan, R.O.C, Division of Hematology and Oncology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taiwan, R.O.C
  • Pages: 495-498
    |
    Published online on: November 9, 2012
       https://doi.org/10.3892/ol.2012.1020
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Abstract

Paraneoplastic eosinophilia is an unusual manifestation that usually remains asymptomatic. In this report, we presented the case of an 82-year-old patient with poorly differentiated lung adenocarcinoma and asymptomatic eosinophilia. The patient's condition worsened rapidly over a week, with episodes of cognitive disturbance, shortness of breath and acute kidney dysfunction. These symptoms were associated with a 4-fold increase in circulating eosinophil counts. The poor condition hindered further anticancer treatment. Treatment of the eosinophilia with corticosteroids and hydroxyurea significantly reduced circulating eosinophil counts to below the initial levels. Results of this case report suggested that lung cancer patients should be monitored closely for rapidly worsening symptoms of cognitive disturbance and respiratory insufficiency as signs of life-threatening asymptomatic eosinophilia, in order to initiate corticosteroid treatment.
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Copy and paste a formatted citation
Spandidos Publications style
Lo C, Jen Y, Tsai W, Chung P and Kao W: Rapidly evolving asymptomatic eosinophilia in a patient with lung adenocarcinoma causes cognitive disturbance and respiratory insufficiency: Case report. Oncol Lett 5: 495-498, 2013.
APA
Lo, C., Jen, Y., Tsai, W., Chung, P., & Kao, W. (2013). Rapidly evolving asymptomatic eosinophilia in a patient with lung adenocarcinoma causes cognitive disturbance and respiratory insufficiency: Case report. Oncology Letters, 5, 495-498. https://doi.org/10.3892/ol.2012.1020
MLA
Lo, C., Jen, Y., Tsai, W., Chung, P., Kao, W."Rapidly evolving asymptomatic eosinophilia in a patient with lung adenocarcinoma causes cognitive disturbance and respiratory insufficiency: Case report". Oncology Letters 5.2 (2013): 495-498.
Chicago
Lo, C., Jen, Y., Tsai, W., Chung, P., Kao, W."Rapidly evolving asymptomatic eosinophilia in a patient with lung adenocarcinoma causes cognitive disturbance and respiratory insufficiency: Case report". Oncology Letters 5, no. 2 (2013): 495-498. https://doi.org/10.3892/ol.2012.1020
Copy and paste a formatted citation
x
Spandidos Publications style
Lo C, Jen Y, Tsai W, Chung P and Kao W: Rapidly evolving asymptomatic eosinophilia in a patient with lung adenocarcinoma causes cognitive disturbance and respiratory insufficiency: Case report. Oncol Lett 5: 495-498, 2013.
APA
Lo, C., Jen, Y., Tsai, W., Chung, P., & Kao, W. (2013). Rapidly evolving asymptomatic eosinophilia in a patient with lung adenocarcinoma causes cognitive disturbance and respiratory insufficiency: Case report. Oncology Letters, 5, 495-498. https://doi.org/10.3892/ol.2012.1020
MLA
Lo, C., Jen, Y., Tsai, W., Chung, P., Kao, W."Rapidly evolving asymptomatic eosinophilia in a patient with lung adenocarcinoma causes cognitive disturbance and respiratory insufficiency: Case report". Oncology Letters 5.2 (2013): 495-498.
Chicago
Lo, C., Jen, Y., Tsai, W., Chung, P., Kao, W."Rapidly evolving asymptomatic eosinophilia in a patient with lung adenocarcinoma causes cognitive disturbance and respiratory insufficiency: Case report". Oncology Letters 5, no. 2 (2013): 495-498. https://doi.org/10.3892/ol.2012.1020
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