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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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December 2012 Volume 4 Issue 6

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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December 2012 Volume 4 Issue 6

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Article

Downregulation of BCSG1 may correlate with better outcome of neoadjuvant chemotherapy for triple-negative breast cancer

  • Authors:
    • Jinsong He
    • Weicai Chen
    • Huisheng Wu
    • Min Wang
    • Yuan Wang
    • Xiaojia She
    • Shufen Song
    • Hong Guan
    • Xianming Wang

  • View Affiliations / Copyright

    Affiliations: Center of Breast Diseases, Second Hospital of Shenzhen, First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong 518035, P.R. China, Center of Breast Diseases, Second Hospital of Shenzhen, First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong 518035, P.R. China, Department of Pathology, Second Hospital of Shenzhen, First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong 518035, P.R. China
  • Pages: 1209-1212
    |
    Published online on: September 12, 2012
       https://doi.org/10.3892/ol.2012.911
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Abstract

The aim of this study was to investigate the correlation between breast cancer-specific gene 1 (BCSG1) and the effect of neoadjuvant chemotherapy (NAC) in patients with triple-negative breast cancer (TNBC). Real-time RT-PCR and immunohistochemistry were used to determine the expression of BCSG1 mRNA and protein levels of 32 TNBC patients before and after NAC. Tumor size was reduced significantly after NAC in all 32 TNBC patients. The expression of BCSG1 was also decreased after NAC at both mRNA and protein levels. There was a negative correlation between BCSG1 levels after NAC and the effect of NAC. BCSG1 may be a potential target for NAC in the treatment of TNBC.
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Copy and paste a formatted citation
Spandidos Publications style
He J, Chen W, Wu H, Wang M, Wang Y, She X, Song S, Guan H and Wang X: Downregulation of BCSG1 may correlate with better outcome of neoadjuvant chemotherapy for triple-negative breast cancer. Oncol Lett 4: 1209-1212, 2012.
APA
He, J., Chen, W., Wu, H., Wang, M., Wang, Y., She, X. ... Wang, X. (2012). Downregulation of BCSG1 may correlate with better outcome of neoadjuvant chemotherapy for triple-negative breast cancer. Oncology Letters, 4, 1209-1212. https://doi.org/10.3892/ol.2012.911
MLA
He, J., Chen, W., Wu, H., Wang, M., Wang, Y., She, X., Song, S., Guan, H., Wang, X."Downregulation of BCSG1 may correlate with better outcome of neoadjuvant chemotherapy for triple-negative breast cancer". Oncology Letters 4.6 (2012): 1209-1212.
Chicago
He, J., Chen, W., Wu, H., Wang, M., Wang, Y., She, X., Song, S., Guan, H., Wang, X."Downregulation of BCSG1 may correlate with better outcome of neoadjuvant chemotherapy for triple-negative breast cancer". Oncology Letters 4, no. 6 (2012): 1209-1212. https://doi.org/10.3892/ol.2012.911
Copy and paste a formatted citation
x
Spandidos Publications style
He J, Chen W, Wu H, Wang M, Wang Y, She X, Song S, Guan H and Wang X: Downregulation of BCSG1 may correlate with better outcome of neoadjuvant chemotherapy for triple-negative breast cancer. Oncol Lett 4: 1209-1212, 2012.
APA
He, J., Chen, W., Wu, H., Wang, M., Wang, Y., She, X. ... Wang, X. (2012). Downregulation of BCSG1 may correlate with better outcome of neoadjuvant chemotherapy for triple-negative breast cancer. Oncology Letters, 4, 1209-1212. https://doi.org/10.3892/ol.2012.911
MLA
He, J., Chen, W., Wu, H., Wang, M., Wang, Y., She, X., Song, S., Guan, H., Wang, X."Downregulation of BCSG1 may correlate with better outcome of neoadjuvant chemotherapy for triple-negative breast cancer". Oncology Letters 4.6 (2012): 1209-1212.
Chicago
He, J., Chen, W., Wu, H., Wang, M., Wang, Y., She, X., Song, S., Guan, H., Wang, X."Downregulation of BCSG1 may correlate with better outcome of neoadjuvant chemotherapy for triple-negative breast cancer". Oncology Letters 4, no. 6 (2012): 1209-1212. https://doi.org/10.3892/ol.2012.911
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