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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2012 Volume 4 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Energy metabolism of cancer: Glycolysis versus oxidative phosphorylation (Review)

Jie Zheng
Pages: 1151-1157
Published online on: 20 September 2012

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Article

Blockade of the sonic hedgehog pathway effectively inhibits the growth of hepatoma in mice: An in vivo study

Kuo-Shyang Jeng, I-Shyan Sheen, Wen-Juei Jeng, Ming‑Che  Yu, Hsin-Hua Tsai, Fang-Yu Chang, Jui-Chih Su
Pages: 1158-1162
Published online on: 24 September 2012

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Case Report

Primary squamous cell carcinoma of the liver: A case report and review of the literature

Rongrong Zhao, Kunli Zhu, Renben Wang, Jie Gao, Kai  Cui, Fachang Yu, Bo Zhang, Sheng Li
Pages: 1163-1166
Published online on: 05 September 2012

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Article

RagD gene expression and NRF2 mutations in lung squamous cell carcinomas

Hidefumi Sasaki, Masayuki Shitara, Keisuke Yokota, Yu Hikosaka, Satoru Moriyama, Motoki Yano, Yoshitaka Fujii
Pages: 1167-1170
Published online on: 25 September 2012

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Case Report

Leiomyoma of the gallbladder in a patient with metastatic gastrointestinal stromal tumor in the liver: A case report with differential diagnostic considerations

Mitsuaki Ishida, Hisanori Shiomi, Shigeyuki Naka, Tohru Tani, Hidetoshi Okabe
Pages: 1171-1173
Published online on: 12 September 2012

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Article

Clear cell neuroendocrine tumor G1 of the gallbladder without von Hippel-Lindau disease

Mitsuaki Ishida, Hisanori Shiomi, Shigeyuki Naka, Tohru Tani, Hidetoshi Okabe
Pages: 1174-1176
Published online on: 06 September 2012

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Article

Effect of radiotherapy on expression of hyaluronan and EGFR and presence of mast cells in squamous cell carcinoma of the head and neck

Eva Lindell Jonsson, Karin Nylander, Lars Hallén, Göran Laurell
Pages: 1177-1182
Published online on: 11 September 2012

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Article

Assessement of angiogenesis reveals blood vessel heterogeneity in lung carcinoma

Amalia Birau, Raluca Amalia Ceausu, Anca Maria Cimpean, Pusa Gaje, Marius Raica, Teodora Olariu
Pages: 1183-1186
Published online on: 05 September 2012

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Article

Expression of cofilin 1 is positively correlated with the differentiation of human epithelial ovarian cancer

Jianwei Zhou, Yinfen Wang, Jing Fei, Weijiang Zhang
Pages: 1187-1190
Published online on: 06 September 2012

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Case Report

Adenosquamous carcinoma of the uncinate process of the pancreas with synchronous gastrointestinal stromal tumor of the stomach: Case report and review of the literature

Jin‑Jie He, Ke‑Feng Ding, Lei Zheng, Jing‑Hong Xu, Jun Li, Yu‑Lian Wu, Li‑Feng Sun, Dong‑Er Zhou, Shu Zheng
Pages: 1191-1194
Published online on: 07 September 2012

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Article

Effects of the proapoptotic regulator Bcl‑2/adenovirus EIB 19‑kDa‑interacting protein 3 on the chemosensitivity of human colon cancer cell lines

Zi Wang, Chunmei Huang, Jianshuang Zeng, Qian Deng, Hui Zeng, Zhen Liu, Xingchen Peng, Feng Bi, Qiulin Tang, Zhiping Li
Pages: 1195-1202
Published online on: 21 September 2012

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Article

Human MutY homolog induces apoptosis in etoposide‑treated HEK293 cells

Soo‑Hyun Hahm, Ji Hyung Chung, Lia Agustina, Se‑Hee Han, In‑Soo Yoon, Jong‑Hwa Park, Lin‑Woo Kang, Jin Woo Park, Jong Joo Na, Ye Sun Han
Pages: 1203-1208
Published online on: 19 September 2012

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Article

Downregulation of BCSG1 may correlate with better outcome of neoadjuvant chemotherapy for triple-negative breast cancer

Jinsong He, Weicai Chen, Huisheng Wu, Min Wang, Yuan Wang, Xiaojia She, Shufen Song, Hong Guan, Xianming Wang
Pages: 1209-1212
Published online on: 12 September 2012

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Article

Immunohistochemical expression of mTOR negatively correlates with PTEN expression in gastric carcinoma

Min Li, Huawen Sun, Lujun Song, Xiaodong Gao, Wenju Chang, Xinyu Qin
Pages: 1213-1218
Published online on: 21 September 2012

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Article

Antitumor effect of the selective COX-2 inhibitor celecoxib on endometrial adenocarcinoma in vitro and in vivo

Yitao Xiao, Yincheng Teng, Rui Zhang, Laimin Luo
Pages: 1219-1224
Published online on: 24 September 2012

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Article

Loss of E‑cadherin promotes prostate cancer metastasis via upregulation of metastasis‑associated gene 1 expression Corrigendum in /10.3892/ol.2020.11421

Liangsheng Fan, Hongyan Wang, Xi Xia, Yumei Rao, Xiangyi Ma, Ding Ma, Peng Wu, Gang Chen
Pages: 1225-1233
Published online on: 21 September 2012

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Article

Recurrent prognostic factors and expression of GLUT‑1, PI3K and p-Akt in adenoid cystic carcinomas of the head and neck: Clinicopathological features and biomarkers of adenoid cystic carcinoma

Jin Fang, Yang-Yang Bao, Shui-Hong Zhou, Xing-Mei Luo, Hong‑Tian Yao, Jian-Feng He, Qin-Ying Wang
Pages: 1234-1240
Published online on: 05 September 2012

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Case Report

Clear cell myoepithelial carcinoma in the base of the tongue: Case report and review of the literature

Jun Hee Park, Ji Yun Choi, Ran Hong, Nam Yong Do
Pages: 1241-1243
Published online on: 07 September 2012

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Article

Perforated gastrointestinal stromal tumor in the jejunum: A rare cause of acute abdomen

Naim Memmi, Gokhan Cipe, Huseyin Bektasoglu, Toygar Toydemir, Huseyin Kadioglu, Suleyman Bozkurt, Nur Buyukpinarbasili, Oguzhan Karatepe, Mahmut Muslumanoglu
Pages: 1244-1246
Published online on: 14 September 2012

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Article

Redox status expressed as GSH:GSSG ratio as a marker for oxidative stress in paediatric tumour patients

Ondrej Zitka, Sylvie Skalickova, Jaromir Gumulec, Michal Masarik, Vojtech Adam, Jaromir Hubalek, Libuse Trnkova, Jarmila Kruseova, Tomas Eckschlager, Rene Kizek
Pages: 1247-1253
Published online on: 21 September 2012

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Article

In vitro and in vivo growth inhibition of drug-resistant ovarian carcinoma cells using a combination of cisplatin and a TRAIL-encoding retrovirus

Fang Li, Yi Guo, Lingfei Han, Yankang Duan, Fang Fang, Sumei Niu, Qiujie Ba, Huaishi Zhu, Fanfei Kong, Chao Lin, Xuejun Wen
Pages: 1254-1258
Published online on: 20 September 2012

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Article

Urotensin II contributes to the formation of lung adenocarcinoma inflammatory microenvironment through the NF-κB pathway in tumor-bearing nude mice

Cheng-Hua Zhou, Ya-Ya Wan, Xiang-Hua Chu, Zheng Song, Shu-Hua Xing, Yu-Qing Wu, Xiao-Xing Yin
Pages: 1259-1263
Published online on: 21 September 2012

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Article

Expression of the pluripotency markers Oct3/4, Nanog and Sox2 in human breast cancer cell lines

Gui-Qin Ling, Dong-Bo Chen, Bao-Qing Wang, Lan-Sheng Zhang
Pages: 1264-1268
Published online on: 13 September 2012

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Article

Effects of cyclooxygenase inhibitors on survival time in ovarian cancer xenograft-bearing mice

Wei Li, Xiao-Li Xu, Jun Zhang, Jia-Hui Cai, Yun-Xian Tang
Pages: 1269-1273
Published online on: 20 September 2012

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Article

DNAJC25 is downregulated in hepatocellular carcinoma and is a novel tumor suppressor gene

Tingting Liu, Wei Jiang, Dingding Han, Long Yu
Pages: 1274-1280
Published online on: 10 September 2012

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Case Report

Successful treatment of unresectable gallbladder cancer with low-dose paclitaxel as palliative chemotherapy after failure of gemcitabine and oral S-1: A case report

Hidehiro Tajima, Tetsuo Ohta, Hiroyuki Shinbashi, Atsushi Hirose, Tomoya Tsukada, Koichi Okamoto, Shinichi Nakanuma, Seisho Sakai, Hiroyuki Furukawa, Isamu Makino, Keishi Nakamura, Hironori Hayashi, Katsunobu Oyama, Masafumi Inokuchi, Hisatoshi Nakagawara, Tomoharu Miyashita, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Fujimura, Hisatsugu Mouri, Koushiro Ohtsubo
Pages: 1281-1284
Published online on: 12 September 2012

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Article

Detection of the Epstein-Barr virus in blood and bone marrow mononuclear cells of patients with aggressive B-cell non‑Hodgkin's lymphoma is not associated with prognosis

Herlander Marques, Raquel Catarino, Nelson Domingues, Eliane Barros, Catarina Portela, Maria Inês Almeida, Sandra Costa, Rui Manuel Reis, Rui Medeiros, Adhemar Longatto-Filho
Pages: 1285-1289
Published online on: 12 September 2012

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Article

microRNA-21 overexpression contributes to cell proliferation by targeting PTEN in endometrioid endometrial cancer

Xiaoyan Qin, Lei Yan, Xingbo Zhao, Chunyan Li, Yibing Fu
Pages: 1290-1296
Published online on: 06 September 2012

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Case Report

Ameloblastic carcinoma of the maxilla: A case report

Diurianne Caroline Campos França, João Milanez Moreira, Sandra Maria Herondina Coelho Ávila De Aguiar, Artur Aburad De Carvalhos, Marcelo Coelho Goiato
Pages: 1297-1300
Published online on: 25 September 2012

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Article

Tagged and untagged TRAIL show different activity against tumor cells

Kunpeng Zhao, Yan'ge Wang, Xueyin Wang, Yugang Wang, Yuanfang Ma
Pages: 1301-1304
Published online on: 11 September 2012

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Article

Fighting cancer from different signalling pathways: Effects of the proteasome inhibitor Bortezomib in combination with the polo-like-kinase-1-inhibitor BI2536 in SCCHN

Martin Leinung, Daniel Hirth, Aykut Tahtali, Marc Diensthuber, Timo Stöver, Jens Wagenblast
Pages: 1305-1308
Published online on: 20 September 2012

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Article

Adjuvant combined systemic chemotherapy and intraperitoneal chemotherapy for locally advanced gastric cancer

Sheng-Liu Xue, Hua-Fang Su, Xiao-Qu Hu, Xia Deng, Mei-Long Hu, Cong-Ying Xie
Pages: 1309-1314
Published online on: 13 September 2012

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Article

Sphere-forming tumor cells possess stem-like properties in human fibrosarcoma primary tumors and cell lines

Wei-Dong Liu, Tao Zhang, Chun-Lei Wang, Hong-Mei Meng, Yu-Wen Song, Zhe Zhao, Zheng-Min Li, Jiang-Kun Liu, Shang-Ha Pan, Wen-Bo Wang
Pages: 1315-1320
Published online on: 26 September 2012

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Article

Downregulation of miR-544 in tissue, but not in serum, is a novel biomarker of malignant transformation in glioma

Ruimin Ma, Guojun Zhang, Huimin Wang, Hong Lv, Fang Fang, Xixiong Kang
Pages: 1321-1324
Published online on: 14 September 2012

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Article

Angiopoietin-like protein ANGPTL2 gene expression is correlated with lymph node metastasis in lung cancer

Hidefumi Sasaki, Ayumi Suzuki, Masayuki Shitara, Yu Hikosaka, Katsuhiro  Okuda, Satoru Moriyama, Motoki Yano, Yoshitaka Fujii
Pages: 1325-1328
Published online on: 20 September 2012

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Case Report

Merkel cell carcinoma with lymph node metastasis in the absence of a primary site: Case report and literature review

Min Zhao, Mao-Bin Meng
Pages: 1329-1334
Published online on: 19 September 2012

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Article

Meta‑analysis of the expression of the mitosis‑related gene Fam83D

Lokman Varisli
Pages: 1335-1340
Published online on: 20 September 2012

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Case Report

Hand-foot syndrome in a patient with metastatic lung adenocarcinoma induced by high-dose icotinib: A case report and review of the literature

Yulong Zheng, Weijia Fang, Nong Xu
Pages: 1341-1343
Published online on: 10 September 2012

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Article

The impact of TGF-β1 on the mRNA expression of TβR I, TβR II, Smad4 and the invasiveness of the JEG-3 placental choriocarcinoma cell line

Yuhong Li, Qian Xu, Zhuo Zhang, Shaochen Liu, Changhua Shi, Yusi Tan
Pages: 1344-1348
Published online on: 11 September 2012

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Article

Role of adjuvant chemotherapy after pneumonectomy for non-small cell lung cancer

Meng Wang, Jing Zhao, Yan-Jun Su, Xiao-Liang Zhao, Chang-Li Wang
Pages: 1349-1353
Published online on: 03 September 2012

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Article

Detection of differentially expressed genes and association with clinicopathological features in laryngeal squamous cell carcinoma

Rong Sheng Ni, Xiaohui Shen, Xiaoyun Qian, Chenjie Yu, Haiyan Wu, Xia Gao
Pages: 1354-1360
Published online on: 18 September 2012

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Article

A cohort study evaluating paraaortic lymphadenectomy in endometrial cancer

Haiyan Zhang, Zhi Zuo, Ye Wang, Li Wang, Zhiling Zhu
Pages: 1361-1365
Published online on: 17 September 2012

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Article

Mimicking pulmonary multiple metastatic tumors: A case of primary nodular parenchymal pulmonary amyloidosis with review of the literature

Li‑Na Zhang, Xin‑Ying Xue, Na Wang, Jian‑Xin Wang
Pages: 1366-1370
Published online on: 20 September 2012

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Article

Primary branchiogenic carcinoma in the first branchial cleft of a child

Yaoshu Teng, Haifei Wang, Rujun Xu, Xinmu Wang, Xiaolin Cao, Yu Fang, Jin Zhu
Pages: 1371-1373
Published online on: 12 September 2012

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Article

GRP78 and GAL3, differentially regulated by lymph node homogenates, as potential biomarkers for lymph node metastasis in mouse hepatocellular carcinoma cells

Wenjun Zhu, Lawrence Owusu, Shizhu Zang, Yunjuan Zhang, Yi Xin, Chao Yan
Pages: 1374-1378
Published online on: 13 September 2012

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Article

Bak is a key molecule in apoptosis induced by methanol extracts of Codonopsis lanceolata and Tricholoma matsutake in HSC-2 human oral cancer cells

Ji-Ae Shin, Jun Sung Kim, In-Sun Hong, Sung-Dae Cho
Pages: 1379-1383
Published online on: 06 September 2012

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Article

8-Chloroadenosine 3',5'-monophosphate induces cell cycle arrest and apoptosis in multiple myeloma cells through multiple mechanisms

Yi-Min Cheng, Qi Zhu, Yi-Yun Yao, Yong Tang, Ming-Ming Wang, Li-Fang Zou
Pages: 1384-1388
Published online on: 11 September 2012

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Case Report

Successful synchronous chemotherapy and radiotherapy followed by consecutive chemotherapy without surgery for primary intracranial choriocarcinoma: A case report

Minjin Kim, Jina Yun, Soon Mi Hur, Jong Joo Moon, Jae Hyung Nam, Se Hyung Kim, Hyun Jung Kim, Chan Kyu Kim, Seong Kyu Park, Dae Sik Hong
Pages: 1389-1391
Published online on: 07 September 2012

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Article

Vitamin D supply: from sun or pill? - Attitudes and recommendation on vitamin D and impact on sun protection practices among German general practitioners evaluated by the network of dermato-oncologists, Onkoderm e.V.

Uwe Reinhold, Thomas Dirschka, Klaus Hartgens, Herbert Kirchesch, Rolf Ostendorf, Holger Petering, Hanspeter Prieur, Gertraud Krähn-Senftleben, Willy J. Malaisse
Pages: 1392-1396
Published online on: 26 September 2012

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Journal Cover
July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu-Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing
Article Number: 321
Published online on: 02 June 2026

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Correction Open Access

[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 320
Published online on: 02 June 2026

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Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Article Open Access

Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Article Open Access

Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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Article Open Access

D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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August-2026 Volume 32 Issue 2

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Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report

Initial chemotherapy decreases transfusion dependence and enables definitive therapy in metastatic thymoma complicated by pure red cell aplasia: A case report

Nobuhito Hara, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Shinichi Ochi, Ryo Miyata, Masatsugu Hamaji, Sayaka Ando, Maiko Takeda, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 354
Published online on: 16 June 2026

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Article Open Access

Bioinformatics analysis of proteins in the complement and coagulation cascades in colon cancer: Discovering the potential biomarker SERPINA1

Da Lian, Daixin Hou, Kunpeng Liu, Hao Jiang, Pengyu Xie
Article Number: 353
Published online on: 16 June 2026

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Article

Circulating miRNA‑30a is associated with favorable therapeutic outcome in patients with gastric cancer treated with neoadjuvant chemotherapy

Vasileia Kokala‑dimitropoulou, Alexandros Mitrousias, Athanasios Tsiatouras, Aigli Vakrakou, Pantelis T. Antonakis, Manousos M. Konstantoulakis
Article Number: 352
Published online on: 16 June 2026

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Case Report Open Access

Salvage robotic‑assisted subtotal esophagectomy after chemoradiotherapy for unresectable locally advanced esophageal sarcoma: A case report

Masaaki Yamamoto, Atsushi Takeno, Kiyoshi Mori, Yumiko Hirose, Shinji Tokuyama, Yuki Matsui, Reishi Toshiyama, Kenji Kawai, Yusuke Takahashi, Kenji Sakai, Naoki Hama, Takeshi Kato, Koji Takami, Motohiro Hirao
Article Number: 351
Published online on: 16 June 2026

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Article Open Access

A prognostic senescence‑related long non‑coding RNA signature identifies cold and hot tumors of stomach adenocarcinoma

Chenxi He, Fanting Kong, Baojuan Han, Litao Lv, Xiaoling Wang, Xiangguang Kong, Qingjiao Zeng, Peipei Zhou
Article Number: 350
Published online on: 16 June 2026

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Article Open Access

Double vs. single autologous stem cell transplantation in patients with multiple myeloma and high‑risk factors: A systematic review and meta‑analysis

Sibei Qin, Yusi Liu, Peng Zhang, Qionglin Zhou, Xiayan Xu, Danbo Liu, Fang Du, Jiao Chen, Lingyun Zhou, Weiling Cao, Haifei Chen
Article Number: 349
Published online on: 16 June 2026

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Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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