Papillary thyroid carcinoma with fibromatosis‑like stroma: A case report and review of the literature

Wu,Zhiming; Chu,Xiufeng; Fan,Shenglong; Meng,Xingcheng; Xu,Chaoyang

doi:10.3892/ol.2012.993

January 2013 Volume 5 Issue 1

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

January 2013 Volume 5 Issue 1

Full Size Image

Case Report

Papillary thyroid carcinoma with fibromatosis‑like stroma: A case report and review of the literature

Authors:
- Zhiming Wu
- Xiufeng Chu
- Shenglong Fan
- Xingcheng Meng
- Chaoyang Xu
View Affiliations / Copyright

Affiliations: Department of General Surgery, Shaoxing Hospital, China Medical University, Shaoxing 312030, P.R. China, Department of Pathology, Shaoxing Hospital, China Medical University, Shaoxing 312030, P.R. China, Department of Breast and Thyroid Surgery, Shaoxing People's Hospital, Shaoxing Hospital of Zhejiang University, Shaoxing, Zhejiang 312000, P.R. China
Pages: 215-217
|
Published online on: October 24, 2012

https://doi.org/10.3892/ol.2012.993
Expand metrics +

Abstract

Papillary thyroid carcinoma with fibromatosis‑like stroma (PTC‑FLS) is a rare type of thyroid carcinoma that does not receive adequate follow‑up. This study describes a case of PTC‑FLS on the right side of the neck. The patient consented to a right hemithyroidectomy with a central compartment lymphadenectomy. Pathological examination revealed that the two initial lesions were consistent with benign histological performance. Using immunohistology, the proliferated stromal cells were revealed to be positive for vimentin and smooth muscle actin (SMA), but negative for thyroglobulin, S‑100 and CK. Post-operative follow‑up was scheduled at 3‑month intervals for 2 years and then at 6‑month intervals for the next 3 years. There were no signs of tumor recurrence at the 5‑year follow-up.

View Figures

View References

1	Mizukami Y, Nonomura A, Matsubara F, Michigishi T, Ohmura K and Hashimoto T: Papillary carcinoma of the thyroid gland with fibromatosis-like stroma. Histopathology. 20:355–357. 1992. View Article : Google Scholar : PubMed/NCBI
2	Mizukami Y, Kurumaya H, Kitagawa T, Minato H, Nonomura A, Michigishi T and Noguchi M: Papillary carcinoma of the thyroid gland with fibromatosis-like stroma: a case report and review of the literature. Mod Pathol. 8:366–370. 1995.PubMed/NCBI
3	Arena S, Salamone S, Cianci R, Scollo C, Masucci R, Giannone G, Manusia M, Vigneri R and La Rosa GL: Aggressive fibromatosis of the neck initiated after thyroidectomy. J Endocrinol Invest. 29:78–81. 2006. View Article : Google Scholar : PubMed/NCBI
4	Schwarzlmüller B and Hofstädter F: Fibromatosis of the thyroid gland region. An electron-microscopic and enzyme-histochemical study. Virchows Arch A Pathol Anat Histol. 377:145–155. 1978.(In German).
5	Shields CJ, Winter DC, Kirwan WO and Redmond HP: Desmoid tumours. Eur J Surg Oncol. 27:701–706. 2001. View Article : Google Scholar : PubMed/NCBI
6	Pepe P, Panella P, Pennisi M and Aragona F: Does color Doppler sonography improve the clinical assessment of patients with acute scrotum? Eur J Radiol. 60:120–124. 2006. View Article : Google Scholar : PubMed/NCBI
7	Russ G, Bigorgne C, Royer B, Rouxel A and Bienvenu Perrard M: The thyroid imaging reporting and data system (TIRADS) for ultrasound of the thyroid. J Radiol. 92:701–713. 2011.(In French).
8	Mizukami Y, Nonomura A, Matsubara F, Michigishi T, Ohmura K and Hashimoto T: Papillary carcinoma of the thyroid gland with fibromatosis-like stroma. Histopathology. 20:355–357. 1992. View Article : Google Scholar : PubMed/NCBI
9	Clark SK and Phillips RK: Desmoids in familial adenomatous polyposis. Br J Surg. 83:1494–1504. 1996. View Article : Google Scholar : PubMed/NCBI
10	Kiel KD and Suit HD: Radiation therapy in the treatment of aggressive fibromatoses (desmoid tumors). Cancer. 54:2051–2055. 1984. View Article : Google Scholar : PubMed/NCBI
11	Ballo MT, Zagars GK, Pollack A, et al: Desmoid tumor: prognostic factors and outcome after surgery, radiation therapy, or combined surgery and radiation therapy. J Clin Oncol. 7:158–167. 1999.PubMed/NCBI
12	Easter DW and Halasz NA: Recent trends in the management of desmoid tumors. Ann Surg. 210:765–769. 1989. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Papillary thyroid carcinoma with fibromatosis‑like stroma: A case report and review of the literature

This article is mentioned in:

Abstract

Figure 1

Related Articles