Glioma in the third trimester of pregnancy: Two cases and a review of the literature

Wu,Jie; Ma,Yan-Hui; Wang,Tian-Long

doi:10.3892/ol.2013.1106

March 2013 Volume 5 Issue 3

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March 2013 Volume 5 Issue 3

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Article

Glioma in the third trimester of pregnancy: Two cases and a review of the literature

Authors:
- Jie Wu
- Yan-Hui Ma
- Tian-Long Wang
View Affiliations / Copyright

Affiliations: Department of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, P.R. China
Pages: 943-946
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Published online on: January 4, 2013

https://doi.org/10.3892/ol.2013.1106
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Abstract

We present two cases of glioma (WHO grade III) in pregnant females presenting in the third trimester. Gliomas during pregnancy are rare. At present, the association between gliomas and pregnancy is poorly understood and little has been reported with regard to the management of patients with gliomas in pregnancy. Management of these cases presents a medical dilemma. Gliomas during pregnancy pose a risk to maternal and fetal life. The benefit‑to‑risk ratio should be carefully evaluated and discussed prior to surgery. In the present cases, caesarean section (CS) followed by craniotomy was performed under the same general anesthesia at 34 weeks' gestation. The mothers received radiotherapy and chemotherapy following surgery. They have been followed up to the present date and remain in good health. These two cases indicate that early CS followed by craniotomy is an effective choice in pregnant patients with gliomas at ≥34 weeks' gestation. In the present study, we describe these two cases and review the literature with regard to gliomas during pregnancy.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Glioma in the third trimester of pregnancy: Two cases and a review of the literature

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