Laparoscopic left pancreatectomy for pancreatic sarcomatoid carcinoma: A case report and review of the literature

Yao,Jie; Qian,Jian-Jun; Zhu,Chang-Ren; Bai,Dou-Sheng; Miao,Yi

doi:10.3892/ol.2013.1411

August 2013 Volume 6 Issue 2

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August 2013 Volume 6 Issue 2

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Case Report

Laparoscopic left pancreatectomy for pancreatic sarcomatoid carcinoma: A case report and review of the literature

Authors:
- Jie Yao
- Jian-Jun Qian
- Chang-Ren Zhu
- Dou-Sheng Bai
- Yi Miao
View Affiliations / Copyright

Affiliations: Department of Hepatobiliary and Pancreatic Surgery, Northern Jiangsu People's Hospital, The First Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China, Department of Pathology, Northern Jiangsu People's Hospital, The First Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China, Center of Pancreatic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China
Pages: 568-570
|
Published online on: June 18, 2013

https://doi.org/10.3892/ol.2013.1411
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Abstract

Sarcomatoid carcinoma of the pancreas is extremely rare. The current report presents a case of carcinosarcoma of the pancreas in a 48-year-old male. Pre‑operative computed tomography scans revealed a large complex cystic and solid mass in the tail of the pancreas; the patient underwent a laparoscopic spleen-preserving left pancreatectomy. The tumor was shown to be made of cystic and solid components, with a grossly grey/white appearance. A histological evaluation of the tumor revealed two elements separated from each other, one component was a pancreatic ductal adenocarcinoma and the other component exhibited a sarcomatous growth pattern, composed of spindle cells and multinucleated giant cells. Immunohistochemically, the epithelial area was positive for cytokeratin (CK) and negative for vimentin, while the sarcomatoid area was negative for CK and positive for vimentin. These observations confirmed a diagnosis of pancreatic carcinosarcoma. Although the patient was treated by gemcitabine following surgery, the outcome was extremely poor and the patient succumbed to sarcomatoid carcinoma three months after the treatment.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Laparoscopic left pancreatectomy for pancreatic sarcomatoid carcinoma: A case report and review of the literature

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