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September 2013 Volume 6 Issue 3

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Case Report

Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non‑tuberculous mycobacteria: A case report and review of the literature

  • Authors:
    • Noriko Inagaki
    • Kayoko Kibata
    • Takeshi Tamaki
    • Toshiki Shimizu
    • Shosaku Nomura
  • View Affiliations / Copyright

    Affiliations: First Department of Internal Medicine, Kansai Medical University, Moriguchi, Osaka 570‑8506, Japan
  • Pages: 676-680
    |
    Published online on: July 15, 2013
       https://doi.org/10.3892/ol.2013.1461
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Abstract

Primary intrahepatic malignant mesothelioma (PIHMM) is an extremely rare tumor with clinicopathological characteristics that remain to be elucidated. The current study presents the case of a 68‑year‑old female with PIHMM and multiple lymphadenopathies due to non‑tuberculous mycobacteria. The patient presented with an intrahepatic tumor, 70 mm in diameter, in the right lobe of the liver. An ultrasound‑guided fine‑needle aspiration biopsy of the liver tumor revealed findings that were consistent with an intrahepatic malignant mesothelioma. The systemic lymph node swellings were due to epithelioid granulomas that were caused by non‑tuberculous mycobacteria. However, a hepatic rupture occurred due to the rapid growth of the liver tumor and consequently, a surgical resection was not performed. A review of the literature revealed that the clinicopathological characteristics of PIHMM are similar to those of non‑occupational mesothelioma. However, PIHMM is usually a solitary tumor and is rarely associated with cavity effusion in contrast with conventional mesothelioma. Therefore, surgical resection with curative intent is often recommended for patients with PIHMM.
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1 

Maitra A and Kumar V: The lung and upper respiratory tract. Robbins Basic Pathology. 7th edition. Saunders; Philadelphia: pp. 453–509. 2002

2 

Battifora H and McCaughey E: Tumors of the Serosal Membranes. Armed Forces Institute of Pathology; Washington, DC: 1994

3 

Thomason R, Schlegel W, Lucca M, et al: Primary malignant mesothelioma of the pericardium. Case report and literature review. Tex Heart Inst J. 21:170–174. 1994.PubMed/NCBI

4 

Kasdon EJ: Malignant mesothelioma of the tunica vaginalis propria testis. Report of two cases Cancer. 23:1144–1150. 1969.PubMed/NCBI

5 

Kozlowski H and Zoltowska A: Mesothelioma of spermatic cord. Neoplasma. 15:97–100. 1968.PubMed/NCBI

6 

Imura J, Ichikawa K, Takeda J, Iwasaki Y, et al: Localized malignant mesothelioma of the epithelial type occurring as a primary hepatic neoplasm: a case report with review of the literature. APMIS. 110:789–794. 2002. View Article : Google Scholar : PubMed/NCBI

7 

Leonardou P, Semelka RC, Kanematsu M, et al: Primary malignant mesothelioma of the liver: MR imaging findings. Magn Reson Imaging. 21:1091–1093. 2003. View Article : Google Scholar : PubMed/NCBI

8 

Gütgemann I, Standop J and Fischer HP: Primary intrahepatic malignant mesothelioma of epithelioid type. Virchows Arch. 448:655–658. 2006.PubMed/NCBI

9 

Kim DS, Lee SG, Jun SY, et al: Primary malignant mesothelioma developed in liver. Hepatogastroenterology. 55:1081–1084. 2008.PubMed/NCBI

10 

Sasaki M, Araki I, Yasui T, et al: Primary localized malignant biphasic mesothelioma of the liver in a patient with asbestosis. World J Gastroenterol. 15:615–621. 2009. View Article : Google Scholar : PubMed/NCBI

11 

Buchholz BM, Gütgemann I, Fischer HP, et al: Lymph node dissection in primary intrahepatic malignant mesothelioma: case report and implications for diagnosis and therapy. Langenbecks Arch Surg. 394:1123–1130. 2009. View Article : Google Scholar : PubMed/NCBI

12 

Husain AN, Colby TV, Ordóñez NG, et al: Guidelines for pathologic diagnosis of malignant mesothelioma: a consensus statement from the International Mesothelioma Interest Group. Arch Pathol Lab Med. 133:1317–1331. 2009.PubMed/NCBI

13 

Yates DH, Corrin B, Stidolph PN and Browne K: Malignant mesothelioma in south east England: clinicopathological experience of 272 cases. Thorax. 52:507–512. 1997.PubMed/NCBI

14 

Borasio P, Berruti A, Billé A, et al: Malignant pleural mesothelioma: clinicopathologic and survival characteristics in a consecutive series of 394 patients. Eur J Cardiothorac Surg. 33:307–313. 2008. View Article : Google Scholar : PubMed/NCBI

15 

Gemba K, Fujimoto N, Kato K, et al: National survey of malignant mesothelioma and asbestos exposure in Japan. Cancer Sci. 103:483–490. 2012. View Article : Google Scholar : PubMed/NCBI

16 

Law MR, Hodson ME and Heard BE: Malignant mesothelioma of the pleura: relation between histological type and clinical behaviour. Thorax. 37:810–815. 1982. View Article : Google Scholar : PubMed/NCBI

17 

Abdel Rahman AR, Gaafar RM, Baki HA, et al: Prevalence and pattern of lymph node metastasis in malignant pleural mesothelioma. Ann Thorac Surg. 86:391–395. 2008.PubMed/NCBI

18 

Edwards JG, Stewart DJ, Martin-Ucar A, et al: The pattern of lymph node involvement influences outcome after extrapleural pneumonectomy for malignant mesothelioma. J Thorac Cardiovasc Surg. 131:981–987. 2006. View Article : Google Scholar : PubMed/NCBI

19 

Metintas M, Metintas S, Ak G, et al: Epidemiology of pleural mesothelioma in a population with non-occupational asbestos exposure. Respirology. 13:117–121. 2008. View Article : Google Scholar : PubMed/NCBI

20 

Saad RS, Lindner JL, Lin X, et al: The diagnostic utility of D2–40 for malignant mesothelioma versus pulmonary carcinoma with pleural involvement. Diagn Cytopathol. 34:801–806. 2006.

21 

Ordóñez NG: The immunohistochemical diagnosis of mesothelioma: A comparative of epithelioid mesothelioma and lung adenocarcinoma. Am J Surg Pathol. 27:1031–1051. 2003.PubMed/NCBI

22 

Roberts F, Harper CM, Downie I and Burnett RA: Immunohistochemical analysis still has a limited role in the diagnosis of malignant mesothelioma. A study of thirteen antibodies. Am J Clin Pathol. 116:253–262. 2001. View Article : Google Scholar : PubMed/NCBI

23 

Pu RT, Pang Y and Michael CW: Utility of WT-1, p63, MOC31, mesothelin, and cytokeratin (K903 and CK5/6) immunostains in differentiating adenocarcinoma, squamous cell carcinoma, and malignant mesothelioma in effusions. Diagn Cytopathol. 36:20–25. 2008. View Article : Google Scholar : PubMed/NCBI

24 

Moch H, Oberholzer M, Christen H, et al: Diagnostic tools for differentiating pleural mesothelioma from lung adenocarcinoma in paraffin embedded tissue. II Design of an expert system and its application to the diagnosis of mesothelioma. Virchows Arch A Pathol Anat Histopathol. 423:493–496. 1993. View Article : Google Scholar : PubMed/NCBI

25 

Attanoos RL and Gibbs AR: Pathology of malignant mesothelioma. Histopathol. 30:403–418. 1997. View Article : Google Scholar : PubMed/NCBI

26 

Tot T: The value of cytokeratins 20 and 7 in discriminating metastatic adenocarcinoma from pleural mesotheliomas. Cancer. 92:2727–2732. 2001. View Article : Google Scholar : PubMed/NCBI

27 

Wang NP, Zee S, Zarbo RJ, et al: Coordinate expression of cytokeratins 7 and 20 defines unique subsets of carcinomas. Appl Immunohistochem. 3:99–107. 1995.

28 

Chu P, Wu E and Weiss LM: Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. Mod Pathol. 13:962–972. 2000. View Article : Google Scholar : PubMed/NCBI

29 

Treglia G, Taralli S, Calcagni ML, et al: Is there a role for fluorine 18 fluorodeoxyglucose-positron emission tomography and positron emission tomography/computed tomography in evaluating patients with mycobacteriosis? A systematic review. J Comput Assist Tomogr. 35:387–393. 2011. View Article : Google Scholar

30 

Das CJ, Kumar R, Balakrishnan VB, et al: Disseminated tuberculosis masquerading as metastatic breast carcinoma on PET-CT. Clin Nucl Med. 33:359–361. 2008. View Article : Google Scholar : PubMed/NCBI

31 

Li YJ, Cai L, Sun HR, et al: Increased FDG uptake in bilateral adrenal tuberculosis appearing like malignancy. Clin Nucl Med. 33:191–192. 2008. View Article : Google Scholar : PubMed/NCBI

32 

Lin WY, Hung GU and Tsai SC: A pitfall of FDG-PET image interpretation: accumulation of FDG in the dependent area of the urinary bladder after bladder irrigation - the usefulness of the prone position. Clin Nucl Med. 30:638–639. 2005. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Inagaki N, Kibata K, Tamaki T, Shimizu T and Nomura S: Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non‑tuberculous mycobacteria: A case report and review of the literature. Oncol Lett 6: 676-680, 2013.
APA
Inagaki, N., Kibata, K., Tamaki, T., Shimizu, T., & Nomura, S. (2013). Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non‑tuberculous mycobacteria: A case report and review of the literature. Oncology Letters, 6, 676-680. https://doi.org/10.3892/ol.2013.1461
MLA
Inagaki, N., Kibata, K., Tamaki, T., Shimizu, T., Nomura, S."Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non‑tuberculous mycobacteria: A case report and review of the literature". Oncology Letters 6.3 (2013): 676-680.
Chicago
Inagaki, N., Kibata, K., Tamaki, T., Shimizu, T., Nomura, S."Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non‑tuberculous mycobacteria: A case report and review of the literature". Oncology Letters 6, no. 3 (2013): 676-680. https://doi.org/10.3892/ol.2013.1461
Copy and paste a formatted citation
x
Spandidos Publications style
Inagaki N, Kibata K, Tamaki T, Shimizu T and Nomura S: Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non‑tuberculous mycobacteria: A case report and review of the literature. Oncol Lett 6: 676-680, 2013.
APA
Inagaki, N., Kibata, K., Tamaki, T., Shimizu, T., & Nomura, S. (2013). Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non‑tuberculous mycobacteria: A case report and review of the literature. Oncology Letters, 6, 676-680. https://doi.org/10.3892/ol.2013.1461
MLA
Inagaki, N., Kibata, K., Tamaki, T., Shimizu, T., Nomura, S."Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non‑tuberculous mycobacteria: A case report and review of the literature". Oncology Letters 6.3 (2013): 676-680.
Chicago
Inagaki, N., Kibata, K., Tamaki, T., Shimizu, T., Nomura, S."Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non‑tuberculous mycobacteria: A case report and review of the literature". Oncology Letters 6, no. 3 (2013): 676-680. https://doi.org/10.3892/ol.2013.1461
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