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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September 2013 Volume 6 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

miRNA: The nemesis of gastric cancer (Review)

Xiaohui Xu, Xiaodong Yang, Chungen Xing, Shuyu Zhang, Jianping Cao
Pages: 631-641
Published online on: 26 June 2013

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Review

Tertiary cytoreduction in the setting of recurrent ovarian cancer (Review)

Nasuh Utku Dogan, Achim Schneider, Vito Chiantera, Selen Dogan, Polat Dursun
Pages: 642-647
Published online on: 04 July 2013

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Article

Polymorphisms of GSTP1, ERCC2 and TS‑3'UTR are associated with the clinical outcome of mFOLFOX6 in colorectal cancer patients

Kensuke Kumamoto, Keiichiro Ishibashi, Norimichi Okada, Yusuke Tajima, Kouki Kuwabara, Yoichi Kumagai, Hiroyuki Baba, Norihiro Haga, Hideyuki Ishida
Pages: 648-654
Published online on: 15 July 2013

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Case Report

Endometrioid adenocarcinoma with choriocarcinomatous differentiation: A case report and review of the literature

Mitsuaki Ishida, Hidetoshi Okabe
Pages: 655-658
Published online on: 28 June 2013

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Article

Identification of high‑risk factors as indicators for adjuvant therapy in stage II colon cancer patients treated at a single institution

Keizo Yamaguchi, Yutaka Ogata, Yoshito Akagi, Kazuo Shirouzu
Pages: 659-666
Published online on: 01 July 2013

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Article

Increased intratumoral fluorothymidine uptake levels following multikinase inhibitor sorafenib treatment in a human renal cell carcinoma xenograft model

Masahiro Murakami, Songji Zhao, Yan Zhao, Wenwen Yu, Chowdhury Nusrat Fatema, Ken‑Ichi Nishijima, Masahiro Yamasaki, Mitsuyoshi Takiguchi, Nagara Tamaki, Yuji Kuge
Pages: 667-672
Published online on: 12 July 2013

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Case Report

A distinct histopathological variant of a malignant melanoma with perivascular pseudorosettes: A case report

Mitsuaki Ishida, Muneo Iwai, Keiko Yoshida, Akiko Kagotani, Hidetoshi Okabe
Pages: 673-675
Published online on: 28 June 2013

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Case Report

Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non‑tuberculous mycobacteria: A case report and review of the literature

Noriko Inagaki, Kayoko Kibata, Takeshi Tamaki, Toshiki Shimizu, Shosaku Nomura
Pages: 676-680
Published online on: 15 July 2013

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Article

Differential expression of filamin A and its clinical significance in breast cancer

Hui‑Min Tian, Xiu‑Hua Liu, Wei Han, Ling‑Ling Zhao, Bo Yuan, Chang‑Ji Yuan
Pages: 681-686
Published online on: 09 July 2013

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Article

Antitumor effects of 32P‑chromic‑poly (L‑lactide) brachytherapy in nude mice with human prostate cancer

Liujing Sun, Xishan Zhu, Longbao Xu, Zizheng Wang, Guoqiang Shao, Jun Zhao
Pages: 687-692
Published online on: 03 July 2013

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Article

-216G/T (rs712829), a functional variant of the EGFR promoter, is associated with the pleural metastasis of lung adenocarcinoma

Haisheng Guo, Yunhui Xing, Ruibao Liu, Shaoping Chen, Xia Bian, Fang Wang, Chunmei Yang, Xunguo Wang
Pages: 693-698
Published online on: 03 July 2013

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Article

Effects of matrine on the proliferation of HT29 human colon cancer cells and its antitumor mechanism

Cheng Chang, Shao‑Ping Liu, Chun‑Hua Fang, Ren‑Sheng He, Zhen Wang, You‑Qing Zhu, Shao‑Wei Jiang
Pages: 699-704
Published online on: 08 July 2013

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Article

Lung cancer and peritoneal carcinomatosis

María Sereno, Isabel Rodríguez‑Esteban, César Gómez‑Raposo, María Merino, Miriam López‑Gómez, Francisco Zambrana, Enrique Casado
Pages: 705-708
Published online on: 15 July 2013

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Case Report

A multiple cavity malignancy involving the renal capsule, pleura and meninges: A case report and review of the literature

Li‑Jing Zhu, Bao‑Rui Liu, Xiao‑Ping Qian, Wei‑Wei Kong, Wen‑Jing Hu, Juan Du, Hai‑Qing Zhu
Pages: 709-712
Published online on: 09 July 2013

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Article

Clinical application of iodine‑eluting stent in patients with advanced esophageal cancer

Zhenbo Dai, Dejun Zhou, Jianzhang Hu, Lei Zhang, Yunshou Lin, Jing Zhang, Fengling Li, Peng Liu, Hua Li, Fuliang Cao
Pages: 713-718
Published online on: 15 July 2013

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Article

Keap1 mutations in lung cancer patients

Hidefumi Sasaki, Ayumi Suzuki, Masayuki Shitara, Katsuhiro Okuda, Yu Hikosaka, Satoru Moriyama, Motoki Yano, Yoshitaka Fujii
Pages: 719-721
Published online on: 26 June 2013

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Case Report

Esophageal cancer presenting as a brain metastasis: A case report

Aldo Spallone, Chiara Izzo
Pages: 722-724
Published online on: 03 July 2013

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Case Report

A novel BRCA1 mutation in a patient with breast and ovarian cancer: A case report

Josefa Salgado, Marta Santisteban, Cristina Gutiérrez, Carmen Gil, Maitane Robles, Adriana Viedma, Ana Patiño-García
Pages: 725-727
Published online on: 03 July 2013

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Article

Metaplastic carcinoma of the breast with transformation from adenosquamous carcinoma to osteosarcomatoid and spindle cell morphology

Suebwong Chuthapisith, Malee Warnnissorn, Nattawut Amornpinyokiat, Kanapon Pradniwat, Tamnit Angsusinha
Pages: 728-732
Published online on: 15 July 2013

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Article

Cyclooxygenase‑2 expression in the tumor environment is associated with poor prognosis in colorectal cancer patients

Peng‑Chan Lin, Yih‑Jyh Lin, Chung‑Ta Lee, Hsiao‑Sheng Liu, Jenq‑Chang Lee
Pages: 733-739
Published online on: 26 June 2013

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Article

Insulin‑like growth factor‑II mRNA‑binding protein 3 predicts a poor prognosis for colorectal adenocarcinoma

Lijuan Lin, Jinhui Zhang, Yan Wang, Weiei Ju, Yibing Ma, Lina Li, Litian Chen
Pages: 740-744
Published online on: 12 July 2013

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Case Report

Primary osteosarcoma of the breast with abundant chondroid matrix and fibroblasts has a good prognosis: A case report and review of the literature

Jingjie Zhao, Xuedong Zhang, Jianwei Liu, Jianhua Li
Pages: 745-747
Published online on: 05 July 2013

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Article

Inhibition of hepatocellular carcinoma growth by adenovirus‑mediated expression of human telomerase reverse transcriptase COOH-27 terminal polypeptide in mice

Lei He, Han-Xian Gong, Xiang-Pen Li, Yi-Dong Wang, Yi Li, Jun-Jian Huang, Dan Xie, Hsiang-Fu Kung, Ying Peng
Pages: 748-752
Published online on: 16 July 2013

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Article

Three cases of a peripheral primitive neuroectodermal tumor diagnosed using computed tomography or magnetic resonance imaging

Junxia Li, Peiyou Gong, Zhushi Guang
Pages: 753-755
Published online on: 15 July 2013

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Article

RNA interference‑mediated targeting of DKK1 gene expression in Ishikawa endometrial carcinoma cells causes increased tumor cell invasion and migration

Nuo Yi, Qin‑Ping Liao, Zhen‑Hua Li, Bao‑Jiang Xie, Yu‑Hong Hu, Wei Yi, Min Liu
Pages: 756-762
Published online on: 03 July 2013

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Article

Identification of TNM stage-specific genes in lung adenocarcinoma by genome-wide expression profiling

Ming Liu, Hong Pan, Feng Zhang, Yongbiao Zhang, Yang Zhang, Han Xia, Jing Zhu, Weiling Fu, Xiaoli Zhang
Pages: 763-768
Published online on: 15 July 2013

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Article

Differential microRNA expression in renal cell carcinoma

Tingting Cheng, Lina Wang, Yuyao Li, Chen Huang, Lingxia Zeng, Jin Yang
Pages: 769-776
Published online on: 12 July 2013

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Article

Expression and clinical significance of cyclin kinase subunit 2 in colorectal cancer

Minhao Yu, Ming Zhong, Zhongdong Qiao
Pages: 777-780
Published online on: 11 July 2013

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Article

Microsurgical treatment for parasagittal meningioma in the central gyrus region

Na Bi, Rui‑Xue Xu, Rong‑Yao Liu, Chun‑Ming Wu, Jian Wang, Wei‑Dong Chen, Jun Liu, You‑Song Xu, Zhen‑Qing Wei, Tao Li, Jian Zhang, Jing‑Yang Bai, Bin Dong, Shu‑Jun Fan, Ying‑Hui Xu
Pages: 781-784
Published online on: 26 June 2013

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Case Report

Identification of a mature cystic teratoma mimicking a presacral tumor by transsacral surgery in a young female: A case report

Yi Yang, Xiaoxiao Wang, Zhenyang Li, Jianbin Xiang, Zongyou Chen
Pages: 785-788
Published online on: 09 July 2013

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Article

microRNA‑199a is able to reverse cisplatin resistance in human ovarian cancer cells through the inhibition of mammalian target of rapamycin

Zhongxian Wang, Zhou Ting, Ya Li, Gang Chen, Yunping Lu, Xing Hao
Pages: 789-794
Published online on: 08 July 2013

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Article

miR‑21 modulates paclitaxel sensitivity and hypoxia‑inducible factor‑1α expression in human ovarian cancer cells

Zhongbin Xie, Liping Cao, Jun Zhang
Pages: 795-800
Published online on: 28 June 2013

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Article

Tissue factor‑targeted lidamycin inhibits growth and metastasis of colon carcinoma

Qing Zhang, Xiujun Liu, Caihong Li, Dongsheng Liao, Zhigang Ouyang, Junnian Zheng, Xu Song
Pages: 801-806
Published online on: 03 July 2013

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Article

Effects of gamma irradiation on cell cycle, apoptosis and telomerase activity in p53 wild‑type and deficient HCT116 colon cancer cell lines

Sevil Oskay Halacli, Hande Canpinar, Eren Cimen, Asuman Sunguroglu
Pages: 807-810
Published online on: 03 July 2013

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Article

Functional analysis of human cancer‑associated genes and their association with the testes and epididymis

Xiu‑Feng Hua, Xue‑Bo Wang, Fu‑Jun Liu
Pages: 811-816
Published online on: 08 July 2013

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Article

Scapular osteochondrolipoma: Imaging features with pathological correlation

Jun Nishio, Soshi Ideta, Hiroshi Iwasaki, Masatoshi Naito
Pages: 817-820
Published online on: 11 July 2013

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Article

Somatostatin receptor subtypes 2 and 5 are associated with better survival in operable hepatitis B‑related hepatocellular carcinoma following octreotide long‑acting release treatment

Yao Liu, Li Jiang, Yi Mu
Pages: 821-828
Published online on: 01 July 2013

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Case Report

Features of a giant cell tumour of the parotid gland: A case report

Cheng-Jung Wu, Pi-Hsiung Wu, Sau-Tung Chu, Wei-Wen Yu, Po-Chun Chen
Pages: 829-832
Published online on: 15 July 2013

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Case Report

Unexpected pheochromocytoma presenting as a pancreatic tumor: A case report

Yi‑Hsuan Huang, Wen‑Jinn Liaw, Chang‑Po Kuo, Zhi-Fu Wu, Chen‑Hwan Cherng, Jyh‑Cherng Yu, Huei‑Chi Horng, Shun‑Tsung Huang
Pages: 833-834
Published online on: 08 July 2013

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Article

Cytokine levels in abdominal exudate predict prolonged postoperative ileus following surgery for colorectal carcinoma

Pengcheng Zhu, Honghua Jiang, Jihong Fu, Wei Chen, Zhongchuan Wang, Long Cui
Pages: 835-839
Published online on: 15 July 2013

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Article

Berberine enhances tumor necrosis factor‑related apoptosis‑inducing ligand‑mediated apoptosis in breast cancer

Alaa Refaat, Sherif Abdelhamed, Hideo Yagita, Hiroki Inoue, Satoru Yokoyama, Yoshihiro Hayakawa, Ikuo Saiki
Pages: 840-844
Published online on: 01 July 2013

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Article

Effects of 5‑Aza‑2'‑deoxycytidine on the methylation state and function of the WWOX gene in the HO‑8910 ovarian cancer cell line

Hongchao Yan, Nan Yu, Jianye Tong
Pages: 845-849
Published online on: 03 July 2013

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Article

An effective approach for treating unresectable hepatoblastoma in infants and children: Pre‑operative transcatheter arterial chemoembolization

Jing Zhang, Fei Xu, Kunshan Chen, Shaoyi Zhou, Haibo Li, Chuanqiang Niu, Xiaoyun Tan
Pages: 850-854
Published online on: 03 July 2013

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Article

A novel taspine derivative suppresses human liver tumor growth and invasion in vitro and in vivo

Nan Wang, Lei Zheng, Yingzhuan Zhan, Yanmin Zhang
Pages: 855-859
Published online on: 09 July 2013

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Article

Inhibition of the enzyme activity of cytochrome P450 1A1, 1A2 and 3A4 by fucoxanthin, a marine carotenoid

Yoshiko Satomi, Hoyoku Nishino
Pages: 860-864
Published online on: 12 July 2013

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Article Open Access

Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Review
Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Article Open Access

Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Article Open Access

Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Article Open Access

Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Article Open Access

Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Article Open Access

Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Review Open Access

Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Review Open Access

Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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Article Open Access

An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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Article Open Access

METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Article Open Access

Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Article Open Access

Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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