Successful pregnancy following conservative management of low‑grade endometrial stromal sarcoma: A case report

Dong,Ruiying; Pang,Yingxin; Mao,Hongluan; Yang,Ning; Liu,Peishu

doi:10.3892/ol.2014.1858

Successful pregnancy following conservative management of low‑grade endometrial stromal sarcoma: A case report

Authors:
- Ruiying Dong
- Yingxin Pang
- Hongluan Mao
- Ning Yang
- Peishu Liu
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Affiliations: Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China
Published online on: February 7, 2014 https://doi.org/10.3892/ol.2014.1858
Pages: 1039-1042

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Abstract

It is uncommon that fertility is preserved in young nulliparous females with low‑grade endometrial stromal sarcoma (ESS). Therefore, successful pregnancy following such conservative management has been rarely reported in previous literature. A 25‑year‑old female (gravida, 0; para, 0) underwent hysteroscopic surgery and was pathologically diagnosed with an endometrial stromal nodule. The patient underwent fertility‑preserving local resection and uterine reconstruction, with a final pathological diagnosis of low‑grade ESS. Endocrine therapy was then administered. Conservative management resulted in the complete remission of low‑grade ESS. The patient naturally conceived and successfully delivered a healthy baby at 42 weeks' gestation by cesarean section, ~30 months following diagnosis with low‑grade ESS. In conclusion, conservative management, including fertility‑preserving local mass resection and endocrine therapy, can be effective for low‑grade ESS and may yield a favorable outcome for young nulliparous females desiring fertility preservation.

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