Low‑grade fibromyxoid sarcoma around the knee involving the proximal end of the tibia and patella: A rare case report

Bajpai,Jeetendra; Shukla,Saurav; Jah,Moazzam; Singh,Alok Kumar; Goel,Mohit; Mourya,Amit; Sachdeva,Nikhil

doi:10.3892/ol.2014.1888

2014-April Volume 7 Issue 4

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

2014-April Volume 7 Issue 4

Full Size Image

Case Report

Low‑grade fibromyxoid sarcoma around the knee involving the proximal end of the tibia and patella: A rare case report

Authors:
- Jeetendra Bajpai
- Saurav Shukla
- Moazzam Jah
- Alok Kumar Singh
- Mohit Goel
- Amit Mourya
- Nikhil Sachdeva
View Affiliations / Copyright

Affiliations: Department of Orthopaedics, Vivekanand Polyclinic and Institute of Medical Sciences, Lucknow, Uttar Pradesh 226016, India
Pages: 1308-1312
|
Published online on: February 17, 2014

https://doi.org/10.3892/ol.2014.1888
Expand metrics +

Abstract

Low‑grade fibromyxoid sarcoma (LGFMS) is a distinctive variant of fibrosarcoma. LGFMS is a rare soft tissue tumor that tends to develop in the deep soft tissue of young adults and has the potential for local recurrence or distant metastasis. The current case report presents a 22‑year‑old male complaining of a slow growing painless mass in the right knee over a period of 10 years. Following complete evaluation by radiological and histopathological examination, a diagnosis of LGFMS was confirmed and a wide excision was performed. Currently, the patient has been under follow‑up for the last five years without any evidence of metastasis. The present case report provides further information concerning the diagnosis, imaging and management of LGFMS.

View Figures

View References

1	Evans HL: Low-grade fibromyxoid sarcoma. A report of two metastasizing neoplasms having a deceptively benign appearance. Am J Clin Pathol. 88:615–619. 1987.
2	Lee BJ, Park WS, Jin JM, Ha CW and Lee SH: Low grade fibromyxoid sarcoma in thigh. Clin Orthop Surg. 1:240–243. 2009. View Article : Google Scholar : PubMed/NCBI
3	Wu X, Petrovic V, Torode IP and Chow CW: Low grade fibromyxoid sarcoma: problems in the diagnosis and management of a malignant tumour with bland histological appearance. Pathology. 41:155–160. 2009. View Article : Google Scholar : PubMed/NCBI
4	Evans HL: Low-grade fibromyxoid sarcoma. A report of 12 cases. Am J Surg Pathol. 17:595–600. 1993. View Article : Google Scholar : PubMed/NCBI
5	Goodlad JR, Mentzel T and Fletcher CD: Low grade fibromyxoid sarcoma: clinicopathological analysis of eleven new cases in support of a distinct entity. Histopathology. 26:229–237. 1995. View Article : Google Scholar
6	Devaney DM, Dervan P, O’Neill S, Carney D and Leader M: Low-grade fibromyxoid sarcoma. Histopathology. 17:463–465. 1990. View Article : Google Scholar
7	Husek K, Janícek P and Jelínek O: Low grade malignant fibromyxoid sarcoma. Cesk Patol. 34:139–141. 1998.(In Czech).
8	Harish K, Ashok AC and Alva NK: Low grade fibromyxoid sarcoma of the falciform ligament: a case report. BMC Surgery. 3:72003. View Article : Google Scholar : PubMed/NCBI
9	Lee SS, Song C, Sun DH and Moon MS: Low grade fibromyxoid sarcoma in shoulder: one case report. J Korean Bone Joint Tumor Soc. 10:130–133. 2004.
10	Vernon SE and Bejarano PA: Low-grade fibromyxoid sarcoma: a brief review. Arch Pathol Lab Med. 130:1358–1360. 2006.PubMed/NCBI
11	Arnaoutoglou C, Lykissas MG, Gelalis ID, Batistatou A, Goussia A, Doukas M and Xenaki TA: Low grade fibromyxoid sarcoma: a case report and review of the literature. J Orthop Surg Res. 5:492010. View Article : Google Scholar : PubMed/NCBI
12	Reid R, de Silva MV, Paterson L, et al: Low-grade fibromyxoid sarcoma and hyalinizing spindle cell tumor with giant rosettes share a common t(7;16)(q34;p11) translocation. Am J Surg Pathol. 27:1229–1236. 2003. View Article : Google Scholar
13	Guillou L, Benhattar J, Gengler C, et al: Translocation-positive low-grade fibromyxoid sarcoma: clinicopathologic and molecular analysis of a series expanding the morphologic spectrum and suggesting potential relationship to sclerosing epithelioid fibrosarcoma: a study from the French Sarcoma Group. Am J Surg Pathol. 31:1387–1402. 2007.
14	Angervall L, Kindblom LG and Merck C: Myxofibrosarcoma. A study of 30 cases. Acta Pathol Microbiol Scand A. 85A:127–140. 1977.PubMed/NCBI
15	Weiss SW and Enzinger FM: Myxoid variant of malignant fibrous histiocytoma. Cancer. 39:1672–1685. 1977. View Article : Google Scholar : PubMed/NCBI
16	Merck C, Angervall L, Kindblom LG and Odén A: Myxofibrosarcoma. A malignant soft tissue tumor of fibroblastic-histiocytic origin A clinicopathologic and prognostic study of 110 cases using multivariate analysis. Acta Pathol Microbiol Immunol Scand Suppl. 282:1–40. 1983.
17	Kindblom LG, Merck C and Angervall L: The ultrastructure of myxofibrosarcoma. A study of 11 cases. Virchows Arch A Pathol Anat Histol. 381:121–139. 1979. View Article : Google Scholar : PubMed/NCBI
18	Miyake M, Tateishi U, Maeda T, Arai Y, Seki K, Hasegawa T and Sugimura K: CT and MRI features of low-grade fibromyxoid sarcoma in the shoulder of a pediatric patient. Radiat Med. 24:511–514. 2006. View Article : Google Scholar : PubMed/NCBI
19	Kim SK, Jee WH, Lee AW and Chung YG: Haemorrhagic low-grade fibromyxoid sarcoma: MR findings in two young women. Br J Radiol. 84:146–150. 2011. View Article : Google Scholar : PubMed/NCBI
20	Folpe A, van den Berg E and Molenaar WM: Low grade fibromyxoid sarcoma. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Fletcher CDM, Unni KK and Mertens F: IARC Press; Lyon: pp. 104–105. 2002
21	Folpe AL, Lane KL, Paull G and Weiss SW: Low-grade fibromyxoid sarcoma and hyalinizing spindle cell tumor with giant rosettes: a clinicopathologic study of 73 cases supporting their identity and assessing the impact of high-grade areas. Am J Surg Pathol. 24:1353–1360. 2000. View Article : Google Scholar

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Low‑grade fibromyxoid sarcoma around the knee involving the proximal end of the tibia and patella: A rare case report

This article is mentioned in:

Abstract

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

Related Articles