Ménétrier's disease, a premalignant condition, with coexisting advanced gastric cancer: A case report and review of the literature

Pryczynicz,Anna; Bandurski,Roman; Guzińska‑Ustymowicz,Katarzyna; Niewiarowska,Katarzyna; Kemona,Andrzej; Kędra,Bogusław

doi:10.3892/ol.2014.2141

Ménétrier's disease, a premalignant condition, with coexisting advanced gastric cancer: A case report and review of the literature

Authors:
- Anna Pryczynicz
- Roman Bandurski
- Katarzyna Guzińska‑Ustymowicz
- Katarzyna Niewiarowska
- Andrzej Kemona
- Bogusław Kędra
View Affiliations

Affiliations: Department of General Pathomorphology, The Medical University of Białystok, Białystok 15‑269, Poland, The Second Department of General and Gastroenterological Surgery, The Medical University of Białystok, Białystok 15‑269, Poland
Published online on: May 13, 2014 https://doi.org/10.3892/ol.2014.2141
Pages: 441-445

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Ménétrier's disease (MD) is a rare type of hypertrophic gastropathy involving the body of the stomach, which is characterized by thickening of the mucous membrane in the form of giant rugal folds, hypochlorhydria and protein loss. The potential for malignant transformation of this lesion remains a controversial topic. Therefore, in the present study, a case of a 51‑year‑old male exhibiting MD with coexisting advanced gastric cancer is described; a review of the literature is also presented. The present case emphasized that MD requires particular attention and should be regarded as a premalignant condition due to the previously documented cases of its coexistence with gastric cancer, in addition to the lack of knowledge regarding its pathogenesis and effective therapeutic management.

View Figures

View References

1	Ménétrier P: Des polyadenomes gastriques et de leurs rapports avec le cancer de l’estomac. Arch Physiol Norm Pathol. 32:236–262. 1888.
2	Rich A, Toro TZ, Tanksley J, et al: Distinguishing Ménétrier’s disease from its mimics. Gut. 59:1617–1624. 2010.
3	Scharschmidt BF: The natural history of hypertrophic gastrophy (Ménétrier’s disease). Report of a case with 16 year follow-up and review of 120 cases from the literature. Am J Med. 63:644–652. 1977.
4	Eisenstat DD, Griffiths AM, Cutz E, Petric M and Drumm B: Acute cytomegalovirus infection in a child with Ménétrier’s disease. Gastroenterology. 109:592–595. 1995.
5	Coffey RJ, Washington MK, Corless CL and Heinrich MC: Ménétrier disease and gastrointestinal stromal tumors: hyperproliferative disorders of the stomach. J Clin Invest. 117:70–80. 2007.
6	Badov D, Lambert JR, Finlay M and Balazs ND: Helicobacter pylori as a pathogenic factor in Ménétrier’s disease. Am J Gastroenterol. 93:1976–1979. 1998.
7	Jun DW, Kim DH, Kim SH, et al: Ménétrier’s disease associated with herpes infection: response to treatment with acyclovir. Gastrointest Endosc. 65:1092–1095. 2007.
8	diSibio G, McPhaul LW, Sarkisian A, Van Pham B and French SW: Ménétrier’s disease associated with Kaposi’s sarcoma. Exp Mol Pathol. 85:160–164. 2008.
9	Ben Amitai D, Zahavi I, Dinari G and Garty BZ: Transient protein-losing hypertrophic gastropathy associated with Mycoplasma pneumoniae infection in childhood. J Pediatr Gastroenterol Nutr. 14:237–239. 1992.
10	Nguyen VX, Nguyen CC, Leighton JA, Pasha SF, Silva AC, Heppell JP and De Petris G: The association of Ménétrier disease with ulcerative colitis: A case report with implications on the pathogenesis of Ménétrier disease. Case Rep Gastroenterol. 4:66–70. 2010.
11	Sobin LH, Gospodarowicz MK and Wittekind C: International Union Against Cancer: TNM classification of malignant tumors. 7th edition. Wiley-Blackwell; New York, NY: 2009
12	Crawford J: The gastrointestinal tract. Pathologic Basis of Disease. Contran RS, Kumar V, Robbins SL and Schoen FJ: WB Saunders Co; Philadelphia, PA: pp. 755–783. 1994
13	Hsu CT, Ito M, Kawase Y, Sekine I, Ohmagari T and Hashimoto S: Early gastric cancer arising from localized Ménétrier’s disease. Gastroenterol Jpn. 26:213–217. 1991.
14	Mosnier JF, Flejou JF, Amouyal G, Gayet B, Molas G, Henin D and Potet F: Hypertrophic gastropathy with gastric adenocarcinoma: Ménétrier’s disease and lymphocytic gastritis? Gut. 32:1565–1567. 1991.
15	Johnson MI, Spark JI, Ambrose NS and Wyatt JI: Early gastric cancer in a patient with Ménétrier’s disease, lymphocytic gastritis and Helicobacter pylori. Eur J Gastroenterol Hepatol. 7:187–190. 1995.
16	Charton-Bain MC, Paraf F and Bruneval P: Superficial gastric carcinoma developed on localized hypertrophic lymphocytic gastritis: a variant of localized Ménétrier’s disease? Pathol Res Pract. 196:125–128. 2000.
17	Kim J, Cheong JH, Chen J, Hyung WJ, Choi SH and Noh SH: Ménétrier’s disease in Korea: report of two cases and review of cases in a gastric cancer prevalent region. Yonsei Med J. 45:555–560. 2004.
18	Sâadia B, Salna BH, Mohamed J, et al: Ménétrier’s disease and gastric carcinoma. Tunis Med. 83:499–502. 2005.(In French).
19	Ramia JM, Sancho E, Lozano O, Santos JM and Domínguez F: Ménétrier’s disease and gastric cancer. Cir Esp. 81:153–154. 2007.(In Spanish).
20	Choi SB, Park SS, Oh SY, et al: Primary squamous cell carcinoma of the stomach that developed with Ménétrier’s disease. Dig Dis Sci. 52:1722–1724. 2007.
21	Salinas Martín MV, Carranza Carranza A and Gavilán Carrasco F: Diffuse gastric carcinoma associated with localized Ménétrier’s disease. Med Clin (Barc). 130:2392008.(In Spanish).
22	Mellado-Castillero JM, Ibáñez-Delgado F, Alcántara-Gijón F, Vázquez-Medina A and Hernández de la Torre JM: Localized Ménétrier’s disease associated with gastric adenocarcinoma. Rev Esp Enferm Dig. 100:60–61. 2008.(In Spanish).
23	Pereyra L, Gómez EJ, Mella JM, et al: Diffuse gastric cancer associated with Ménétrier’s disease. Acta Gastroenterol Latinoam. 41:142–145. 2011.(In Spanish).
24	Famularo G, Sajeva MR and Gasbarrone L: Beyond gastritis and before cancer: the strange case of Ménétrier’s disease. Intern Emerg Med. 6:369–371. 2011.
25	Wood MG, Bates C, Brown RC and Losowsky MS: Intramucosal carcinoma of the gastric antrum complicating Ménétrier’s disease. J Clin Pathol. 36:1071–1075. 1983.