Oral anticancer agent medication adherence by outpatients

Kimura,MIchio; Usami,EIseki; Iwai,Mina; Nakao,Toshiya; Yoshimura,Tomoaki; Mori,Hiromi; Sugiyama,Tadashi; Teramachi,Hitomi

doi:10.3892/ol.2014.2480

November-2014 Volume 8 Issue 5

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November-2014 Volume 8 Issue 5

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Article

Oral anticancer agent medication adherence by outpatients

Authors:
- MIchio Kimura
- EIseki Usami
- Mina Iwai
- Toshiya Nakao
- Tomoaki Yoshimura
- Hiromi Mori
- Tadashi Sugiyama
- Hitomi Teramachi
View Affiliations / Copyright

Affiliations: Department of Pharmacy, Ogaki Municipal Hospital, Ogaki, Japan, Laboratory of Clinical Pharmacy Practice and Social Science, Gifu Pharmaceutical University, Gifu, Japan, Laboratory of Clinical Pharmacy, Gifu Pharmaceutical University, Gifu, Japan
Pages: 2318-2324
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Published online on: August 26, 2014

https://doi.org/10.3892/ol.2014.2480
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Abstract

In the present study, medication adherence and factors affecting adherence were examined in patients taking oral anticancer agents. In June 2013, 172 outpatients who had been prescribed oral anticancer agents by Ogaki Municipal Hospital (Ogaki, Gifu, Japan) completed a questionnaire survey, with answers rated on a five‑point Likert scale. The factors that affect medication adherence were evaluated using a customer satisfaction (CS) analysis. For patients with good and insufficient adherence to medication, the median ages were 66 years (range, 21‑85 years) and 73 years (range, 30‑90 years), respectively (P=0.0004), while the median dosing time was 131 days (range, 3‑3,585 days) and 219 days (24‑3,465 days), respectively (P=0.0447). In 36.0% (62 out of 172) of the cases, there was insufficient medication adherence; 64.5% of those cases (40 out of 62) showed good medication compliance (4‑5 point rating score). However, these patients did not fully understand the effects or side‑effects of the drugs, giving a score of three points or less. The percentage of patients with good medication compliance was 87.2% (150 out of 172). Through the CS analysis, three items, the interest in the drug, the desire to consult about the drug and the condition of the patient, were extracted as items for improvement. Overall, the medication compliance of the patients taking the oral anticancer agents was good, but the medication adherence was insufficient. To improve medication adherence, a better understanding of the effectiveness and necessity of drugs and their side‑effects is required. In addition, the interest of patients in their medication should be encouraged and intervention should be tailored to the condition of the patient. These steps should lead to improved medication adherence.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Oral anticancer agent medication adherence by outpatients

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Abstract

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