Rapidly growing and ulcerating metastatic renal cell carcinoma of the lower lip: A case report and review of the literature

Suojanen,Juho; Färkkilä,Esa; Helkamaa,Tessa; Loimu,Venla; Törnwall,Jyrki; Lindqvist,Christian; Hagström,Jaana; Mesimäki,Karri

doi:10.3892/ol.2014.2505

Rapidly growing and ulcerating metastatic renal cell carcinoma of the lower lip: A case report and review of the literature

Authors:
- Juho Suojanen
- Esa Färkkilä
- Tessa Helkamaa
- Venla Loimu
- Jyrki Törnwall
- Christian Lindqvist
- Jaana Hagström
- Karri Mesimäki
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Affiliations: Department of Oral and Maxillofacial Diseases, Helsinki University Central Hospital, Helsinki FIN‑00014, Finland, Department of Oral and Maxillofacial Diseases, Helsinki University Central Hospital, Helsinki FIN‑00014, Finland, Department of Oncology, Helsinki University Central Hospital, Helsinki FIN‑00014, Finland, The Haartman Institute, Department of Pathology and HUSLAB, Helsinki University Central Hospital, Helsinki FIN‑00014, Finland
Published online on: September 5, 2014 https://doi.org/10.3892/ol.2014.2505
Pages: 2175-2178

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Abstract

Renal cell carcinomas (RCCs) have a tendency to metastasize at an early stage, therefore, the patients frequently exhibit metastatic disease at the time of diagnosis. Common locations for the metastases are adjacent organs and abdominal lymph nodes; however, occasionally metastasis to the peripheral organs may be the initial clinical symptom. The 71‑year‑old male patient in the current case suffered from radioresistant and aggressively behaving RCC metastasis in the mandible and lower lip, which was successfully managed by surgical resection. RCC metastasis to the facial area is considered to be uncommon based on a review of the existing literature. RCC are somewhat radioresistant and therefore, palliative surgery must be considered when treating patients with this metastatic disease.

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