First adult case of sporadic localized glomerulocystic kidney mimicking a tumor

Kojima,Fumiyoshi; Ishida,Mitsuaki; Tsujimoto,Yuichi; Hosomi,Masahiro; Toshiaki,Kinouchi; Okabe,Hidetoshi

doi:10.3892/ol.2015.3060

May-2015 Volume 9 Issue 5

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May-2015 Volume 9 Issue 5

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Article

First adult case of sporadic localized glomerulocystic kidney mimicking a tumor

Authors:
- Fumiyoshi Kojima
- Mitsuaki Ishida
- Yuichi Tsujimoto
- Masahiro Hosomi
- Kinouchi Toshiaki
- Hidetoshi Okabe
View Affiliations / Copyright

Affiliations: Department of Diagnostic Pathology, Saiseikai Senri Hospital, Suita, Osaka 565‑0862, Japan, Department of Clinical Laboratory Medicine and Division of Diagnostic Pathology, Shiga University of Medical Science, Otsu, Shiga 520‑2192, Japan, Department of Urology, Saiseikai Senri Hospital, Suita, Osaka 565‑0862, Japan
Pages: 2368-2370
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Published online on: March 20, 2015

https://doi.org/10.3892/ol.2015.3060
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Abstract

Glomerulocystic kidneys (GCKs) are mainly observed in infants and young children, and are characterized by the cystic dilatation of Bowman's space to form glomerular cysts (GCs). GCKs are associated with various conditions. Additionally, the cystogenesis of GCKs remains controversial. The present study describes a rare adult case of a sporadic localized GCK that radiologically mimicked a multilocular cystic tumor, and analyses the features of GC. A 42‑year‑old male with hematuria underwent a right partial nephrectomy for a cystic mass. The majority of the cyst was distributed in the cortex and contained a single collapsed glomerulus. Using serial sections, narrow and serpiginous proximal tubules that continued to the GCs were detected. These findings suggested that obliteration at the glomerulotubular junction was not the primary cause of GC in this case. To the best of our knowledge, this is the first adult case of a sporadic localized GCK mimicking a tumor. Unnecessary surgical procedures may be avoided by careful evaluation of computed tomography scans and magnetic resonance imaging, although localized GCKs are quite rare.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

First adult case of sporadic localized glomerulocystic kidney mimicking a tumor

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