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Use of a novel herbal medicine in a 75‑year‑old woman with multi‑metastatic pancreatic cancer: A case report and review of the literature

  • Authors:
    • Yanchu Li
    • Xianyong Li
    • Pairotetorsak Tip
    • Lingyan Zhang

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  • Published online on: May 20, 2015     https://doi.org/10.3892/ol.2015.3237
  • Pages: 263-267
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Abstract

Pancreatic cancer is one of the most aggressive types of malignant tumors and is associated with an extremely poor prognosis. Despite numerous research efforts over the last few years, little progress has been made in the understanding and treatment of the disease. Gemcitabine‑based regimens are considered as the first‑line treatment for pancreatic cancer, but the effects of chemotherapy on the disease are limited. Natural products extracted from herbs represent a valuable resource for novel bioactive anticancer agents and could benefit multi‑metastasis pancreatic adenocarcinoma patients with an Eastern Cooperative Oncology Group status of 3. Biological intra‑control cancer treatment (BICT) is a novel systemic therapy involving palliative care and herbal extract combinations [including ginseng (Panax ginseng C.A. Mey.), Herba Agrimonia (Agrimonia pilosa Ledeb.), White Flower Patrinia Herb (Thlaspi arvense Linn.) and arginine], which has been approved by the State Food and Drug Association. The treatment is intended to regulate and inhibit blood vessel generation and tumor growth by inhibiting epidermal growth factor receptor and vascular endothelial growth factor receptor expression, and to manage symptoms to improve the quality of the treatment. The present study discusses the case of a 75‑year‑old female diagnosed with pancreatic cancer with multiple metastases in the liver and lymph nodes. The patient was administered BICT and achieved survival for 11 months without side‑effects of a severity greater than grade 1 according to the Common Terminology Criteria for Adverse Events. The study also describes a possible approach to providing palliative care and treating late‑stage, metastatic pancreatic adenocarcinomas in elderly patients.
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July-2015
Volume 10 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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  • Journal Metrics
  • Impact Factor: 2.9
  • Ranked Oncology
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  • CiteScore: 6.3
  • CiteScore Rank: Q2: #119/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.725
  • SCImago Journal Rank (SJR): 0.639
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Spandidos Publications style
Li Y, Li X, Tip P and Zhang L: Use of a novel herbal medicine in a 75‑year‑old woman with multi‑metastatic pancreatic cancer: A case report and review of the literature. Oncol Lett 10: 263-267, 2015
APA
Li, Y., Li, X., Tip, P., & Zhang, L. (2015). Use of a novel herbal medicine in a 75‑year‑old woman with multi‑metastatic pancreatic cancer: A case report and review of the literature. Oncology Letters, 10, 263-267. https://doi.org/10.3892/ol.2015.3237
MLA
Li, Y., Li, X., Tip, P., Zhang, L."Use of a novel herbal medicine in a 75‑year‑old woman with multi‑metastatic pancreatic cancer: A case report and review of the literature". Oncology Letters 10.1 (2015): 263-267.
Chicago
Li, Y., Li, X., Tip, P., Zhang, L."Use of a novel herbal medicine in a 75‑year‑old woman with multi‑metastatic pancreatic cancer: A case report and review of the literature". Oncology Letters 10, no. 1 (2015): 263-267. https://doi.org/10.3892/ol.2015.3237