Iris metastasis from esophageal squamous cell carcinoma: A case report
- Authors:
- Donglai Lv
- Zongtao Hu
- Chong Wang
- Shile Gao
- Jun Xu
View Affiliations
Affiliations: Department of Clinical Oncology, The 105 Hospital of The People's Liberation Army, Hefei, Anhui 230031, P.R. China, Department of Pathology, The 105 Hospital of The People's Liberation Army, Hefei, Anhui 230031, P.R. China
- Published online on: May 22, 2015 https://doi.org/10.3892/ol.2015.3255
-
Pages:
790-792
-
Copyright: © Lv
et al. This is an open access article distributed under the
terms of Creative
Commons Attribution License.
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Abstract
Carcinoma metastatic to the eye is a rare condition, typically associated with a poor prognosis. Breast and lung cancers are the most common sources of intraocular metastases, and the majority of metastatic lesions involve the posterior uvea, with <8% of reported cases arising in the iris. Intraocular metastasis as the presenting form of esophageal carcinoma is highly uncommon. In the present report, a rare case of metastatic iris tumor resulting from esophageal squamous cell carcinoma is discussed. A 64‑year‑old patient presented with a progressively distending pain in the right eye, with associated blurred vision. Local and systemic evaluation was performed, followed by treatment. Multiple examinations identified a neoplasm in the right iris and postoperative pathology revealed that the iris lesion was a metastasis of esophageal squamous cell cancer origin. The patient was treated with adjuvant radiation. To the best of our knowledge, this was only the second reported case of esophageal squamous cell carcinoma metastasizing to the iris.
View References
|
1
|
Kato H and Nakajima M: Treatments for
esophageal cancer: A review. Gen Thorac Cardiovasc Surg.
61:330–335. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Shields CL, Shields JA, Gross NE, Schwartz
GP and Lally SE: Survey of 520 eyes with uveal metastases.
Ophthalmology. 104:1265–1276. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Knezevic J, Radovanovic N, Simic A, Bobić
Radovanović A, Latković Z, Micev M and Pesko P: Isolated choroidal
metastasis from primary adenocarcinoma of the distal esophagus: A
case report. Dis Esophagus. 16:41–43. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Buskens CJ, Tan HS, Hulscher JB, de Smet
MD and van Lanschot JJ: Adenocarcinoma of the esophagus with
choroidal metastasis. Dis Esophagus. 14:70–72. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Parikh HK, Deshpande RK, Swaroop DV and
Desai PB: Choroidal metastasis from primary adenocarcinoma of the
esophagus - a case report. Indian J Cancer. 29:210–214.
1992.PubMed/NCBI
|
|
6
|
d'Abbadie I, Arriagada R, Spielmann M and
Lê MG: Choroid metastases: Clinical features and treatments in 123
patients. Cancer. 98:1232–1238. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Kim CY, Ha CW and Lee SC: Vitreous and
retinal metastasis from gastric cancer. Eur J Ophthalmol.
20:615–617. 2010.PubMed/NCBI
|
|
8
|
Albert DM, Zimmermann AW Jr and Zeidman I:
Tumor metastasis to the eye. 3. The fate of circulating tumor cells
to the eye. Am J Ophthalmol. 63:733–738. 1967. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Shields JA, Shields CL, Kiratli H and de
Potter P: Metastatic tumors to the iris in 40 patients. Am J
Ophthalmol. 119:422–430. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Giuliari GP and Sadaka A: Uveal metastatic
disease: Current and new treatment options (review). Oncol Rep.
27:603–607. 2012.PubMed/NCBI
|
|
11
|
Lee WB, Sy HM, Filip DJ and Grossniklaus
HE: Metastatic esophageal adenocarcinoma presenting in the iris. Am
J Ophthalmol. 144:477–479. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Ichiki Y, Morita M, Yano K, Sugio K,
Yasumoto K and Hirose N: Iris metastasis of esophageal cancer. Ann
Thorac Surg. 79:1782–1784. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Freedman MI and Folk JC: Metastatic tumors
to the eye and orbit. Patient survival and clinical
characteristics. Arch Ophthalmol. 105:1215–1219. 1987. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kanthan GL, Jayamohan J, Yip D and Conway
RM: Management of metastatic carcinoma of the uveal tract: An
evidence-based analysis. Clin Experiment Ophthalmol. 35:553–565.
2007. View Article : Google Scholar : PubMed/NCBI
|
