Laryngeal function reconstruction with hyoid osteomuscular flap in partial laryngectomy for laryngeal cancer

Wei,Bojun; Shen,Hong; Xie,Hong

doi:10.3892/ol.2015.3362

August-2015 Volume 10 Issue 2

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

August-2015 Volume 10 Issue 2

Full Size Image

Article Open Access

Laryngeal function reconstruction with hyoid osteomuscular flap in partial laryngectomy for laryngeal cancer

Authors:
- Bojun Wei
- Hong Shen
- Hong Xie
View Affiliations / Copyright

Affiliations: Department of Otorhinolaryngology Head and Neck Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, P.R. China

Copyright: © Wei et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 637-640
|
Published online on: June 11, 2015

https://doi.org/10.3892/ol.2015.3362
Expand metrics +

Abstract

The present study aimed to evaluate the clinical outcome of using a hyoid osteomuscular flap to repair the laryngeal defect after extended vertical partial laryngectomy. A total of 26 glottic cancer patients underwent reconstruction with osteomuscular hyoid flaps following tumor resections. Ipsilateral arytenoid cartilage was resected in all cases, and the upper region of the cricoid cartilage was resected in 11 cases. Selective ipsilateral level II, III and IV neck dissections were performed in node (N)‑positive patients and ipsilateral level II, and III neck dissections in N0 patients. The bone grafts were then fixed to the cricoid and contralateral thyroid cartilages. Invasion of the thyroid cartilage endochorium was present in 12 cases and lymph nodes metastases was present in 11 cases. The extubation rate of the tracheostomy tube was 100%. The glottides of all patients were almost symmetrical. Patients were followed up for 2‑7 years. One patient developed local recurrence, ipsilateral regional recurrence, contralateral regional recurrence and lung metastasis, respectively. The disease‑free survival rates at 3 and 5 years were 100% (20/20) and 79% (11/14), respectively. Overall, laryngeal function recovered well upon hyoid osteomuscular flap reconstruction following extended vertical partial laryngectomy, with a high extubation rate and good sound quality.

View Figures

View References

1	van Dijk BA, Karim-Kos HE, Coebergh JW, Marres HA and de Vries E: Progress against laryngeal cancer in The Netherlands between 1989 and 2010. Int J Cancer. 134:674–681. 2014. View Article : Google Scholar : PubMed/NCBI
2	Pucher B and Grzegorowski M: Surgical treatment of laryngomalacia in children. Otolaryngol Pol. 60:349–354. 2006.(Article in Polish). PubMed/NCBI
3	Forastiere AA, Goepfert H, Maor M, et al: Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer. N Engl J Med. 349:2091–2098. 2003. View Article : Google Scholar : PubMed/NCBI
4	Hoffman HT, Porter K, Karnell LH, et al: Laryngeal cancer in the United States: changes in demographics, patterns of care and survival. Laryngoscope. 116:(Suppl 111). 1–13. 2006. View Article : Google Scholar : PubMed/NCBI
5	Silver CE, Beitler JJ, Shaha AR, et al: Current trends in initial management of laryngeal cancer: the declining use of open surgery. Eur Arch Otorhinolaryngol. 266:1333–1352. 2009. View Article : Google Scholar : PubMed/NCBI
6	Liu B, Pan Z and Ji W: Reconstruction of laryngeal defect in vertical partial laryngectomy with resection of arytenoid cartilage. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 40:52–55. 2005.(In Chinese). PubMed/NCBI
7	Ulualp SO: Mapping regional laryngopharyngeal mechanoreceptor response. Clin Exp Otorhinolaryngol. 7:319–323. 2014. View Article : Google Scholar : PubMed/NCBI
8	Ouyang D1, Liu TR, Liu XW, Chen YF, Wang J, Su X and Yang AK: Combined hyoid bone flap in laryngeal reconstruction after extensive partial laryngectomy for laryngeal cancer. Eur Arch Otorhinolaryngol. 270:1455–1462. 2013. View Article : Google Scholar : PubMed/NCBI
9	Diab S, Pascoe J, Shahriar M, Read D, Kinde H, Moore J, Odani J and Uzal F: Study of laryngopharyngeal pathology in Thoroughbred horses in southern california. Equine Vet J. 41:903–907. 2009. View Article : Google Scholar : PubMed/NCBI
10	Jia S, Sun B and Shang L: Extended vertical partial laryngectomy for treatment of the glottic cancer with T3 category. Zhonghua Er Bi Yan Hou Ke Za Zhi. 31:365–367. 1996.(In Chinese). PubMed/NCBI
11	Tu G, Tang P and He Y: The use of hyoid osteomuscular flap in extended partial laryngectomy. Zhonghua Er Bi Yan Hou Ke Za Zhi. 31:39–42. 1996.(In Chinese). PubMed/NCBI
12	Yan D, Zhang B, Qi Y, et al: Supracricoid partial laryngectomy versus other traditional partial laryngectomy for selected laryngeal cancers. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 24:828–831. 2010.(In Chinese). PubMed/NCBI
13	Zhang SY, Lu ZM, Chen LS, et al: Supracricoid partial laryngectomy cricohyoidoepiglottopexy (SCPL-CHEP) versus vertical partial laryngectomy for the treatment of glottic carcinoma. Eur Arch Otorhinolaryngol. 270:1027–1034. 2013. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Laryngeal function reconstruction with hyoid osteomuscular flap in partial laryngectomy for laryngeal cancer

This article is mentioned in:

Abstract

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Related Articles