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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Case Report

Gd‑EOB‑DTPA‑enhanced and diffusion‑weighted magnetic resonance findings in hepatic epithelioid angiomyolipoma: A case report

  • Authors:
    • Jun Sun
    • Shouan Wang
    • Wenxin Chen
    • Jingtao Wu
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Northern Jiangsu People's Hospital, Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China
  • Pages: 1145-1148
    |
    Published online on: June 11, 2015
       https://doi.org/10.3892/ol.2015.3368
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Abstract

The present study reports a case of histologically proven hepatic epithelioid angiomyolipoma that was evaluated with gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd‑EOB‑DTPA)‑enhanced magnetic resonance imaging and diffusion‑weighted imaging. A 23‑year‑old female was admitted to the Northern Jiangsu People's Hospital (Yangzhou, Jiangsu, China) due to a 5.6‑cm mass in the liver, and a right partial hepatectomy was performed. Magnetic resonance imaging (MRI) revealed a hypointense mass on T1‑weighted imaging, and a hyperintense mass on T2‑weighted and diffusion‑weighted imaging, with a higher apparent diffusion coefficient value compared with normal liver parenchyma. On the dynamic Gd‑EOB‑DTPA‑enhanced MRI scan, the lesion manifested as hypervascular with multiple filiform vessels and a pseudocapsule image, and in the hepatobiliary phase the lesion demonstrated a lack of contrast retention, thus appearing hypointense compared with the background liver. Pre‑operatively, EMAL was diagnosed on the basis of these findings in the tumor. The optimum treatment is complete surgical excision and subsequent follow‑up. The patient was healthy and free from recurrence at 6 months and 1 year post‑surgery. Therefore, knowledge of EAML specific features on dynamic Gd‑EOB‑DTPA‑enhanced and DWI scans may improve the diagnostic accuracy of hypervascular hepatic tumors and may facilitate treatment selection.
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1 

Xu PJ, Shan Y, Yan FH, Ji Y, Ding Y and Zhou ML: Epithelioid angiomyolipoma of the liver: Cross-sectional imaging findings of 10 immunohistochemically-verified cases. World J Gastroenterol. 15:4576–4581. 2009. View Article : Google Scholar : PubMed/NCBI

2 

Lane BR, Aydin H, Danforth TL, Zhou M, Remer EM, Novick AC and Campbell SC: Clinical correlates of renal angiomyolipoma subtypes in 209 patients: Classic, fat poor, tuberous sclerosis associated and epithelioid. J Urol. 180:836–843. 2008. View Article : Google Scholar : PubMed/NCBI

3 

Schuhmann-Giampieri G, Schmitt-Willich H, Press WR, Negishi C, Weinmann HJ and Speck U: Preclinical evaluation of Gd-EOB-DTPA as a contrast agent in MR imaging of the hepatobiliary system. Radiology. 183:59–64. 1992. View Article : Google Scholar : PubMed/NCBI

4 

Motosugi U, Ichikawa T, Sou H, Sano K, Tominaga L, Muhi A and Araki T: Distinguishing hypervascular pseudolesions of the liver from hypervascular hepatocellular carcinomas with gadoxetic acid-enhanced MR imaging. Radiology. 256:151–158. 2010. View Article : Google Scholar : PubMed/NCBI

5 

Ahn SS, Kim MJ, Lim JS, Hong HS, Chung YE and Choi JY: Added value of gadoxetic acid-enhanced hepatobiliary phase MR imaging in the diagnosis of hepatocellular carcinoma. Radiology. 255:459–466. 2010. View Article : Google Scholar : PubMed/NCBI

6 

Miller FH, Hammond N, Siddiqi AJ, Shroff S, Khatri G, Wang Y, Merrick LB and Nikolaidis P: Utility of diffusion-weighted MRI in distinguishing benign and malignant hepatic lesions. J Magn Reson Imaging. 32:138–147. 2010. View Article : Google Scholar : PubMed/NCBI

7 

Parikh T, Drew SJ, Lee VS, Wong S, Hecht EM, Babb JS and Taouli B: Focal liver lesion detection and characterization with diffusion-weighted MR imaging: Comparison with standard breath-hold T2-weighted imaging. Radiology. 246:812–822. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Tsui WM, Colombari R, Portmann BC, Bonetti F, Thung SN, Ferrell LD, Nakanuma Y, Snover DC, Bioulac-Sage P and Dhillon AP: Hepatic angiomyolipoma: A clinicopathologic study of 30 cases and delineation of unusual morphologic variants. Am J Surg Pathol. 23:34–48. 1999. View Article : Google Scholar : PubMed/NCBI

9 

Ren N, Qin LX, Tang ZY, Wu ZQ and Fan J: Diagnosis and treatment of hepatic angiomyolipoma in 26 cases. World J Gastroenterol. 9:1856–1858. 2003.PubMed/NCBI

10 

Nguyen TT, Gorman B, Shields D and Goodman Z: Malignant hepatic angiomyolipoma: Report of a case and review of literature. Am J Surg Pathol. 32:793–798. 2008. View Article : Google Scholar : PubMed/NCBI

11 

Graziano A, Santangelo M and Umana DS: Clinical evaluation of epithelioid angiomyolipoma. Ann Ital Chir. 79:135–138. 2008.PubMed/NCBI

12 

Xie L, Jessurun J, Manivel JC and Pambuccian SE: Hepatic epithelioid angiomyolipoma with trabecular growth pattern: A mimic of hepatocellular carcinoma on fine needle aspiration cytology. Diagn Cytopathol. 40:639–650. 2012. View Article : Google Scholar : PubMed/NCBI

13 

Agaimy A, Vassos N, Croner RS, Strobel D and Lell M: Hepatic angiomyolipoma: A series of six cases with emphasis on pathological-radiological correlations and unusual variants diagnosed by core needle biopsy. Int J Clin Exp Pathol. 5:512–521. 2012.PubMed/NCBI

14 

Ji JS, Lu CY, Wang ZF, Xu M and Song JJ: Epithelioid angiomyolipoma of the liver: CT and MRI features. Abdom Imaging. 38:309–314. 2013. View Article : Google Scholar : PubMed/NCBI

15 

Zhao Y, Ouyang H, Wang X, Ye F and Liang J: MRI manifestations of liver epithelioid and nonepithelioid angiomyolipoma. J Magn Reson Imaging. 39:1502–1508. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Xu PJ, Yan FH, Wang JH, Shan Y, Ji Y and Chen CZ: Contribution of diffusion-weighted magnetic resonance imaging in the characterization of hepatocellular carcinomas and dysplastic nodules in cirrhotic liver. J Comput Assist Tomogr. 34:506–512. 2010. View Article : Google Scholar : PubMed/NCBI

17 

Zech CJ, Grazioli L, Breuer J, Reiser MF and Schoenberg SO: Diagnostic performance and description of morphological features of focal nodular hyperplasia in Gd-EOB-DTPA-enhanced liver magnetic resonance imaging: Results of a multicenter trial. Invest Radiol. 43:504–511. 2008. View Article : Google Scholar : PubMed/NCBI

18 

Donati F, Boraschi P, Gigoni R, Salemi S, Falaschi F and Bartolozzi C: Focal nodular hyperplasia of the liver: Diffusion and perfusion MRI characteristics. Magn Reson Imaging. 31:10–16. 2013. View Article : Google Scholar : PubMed/NCBI

19 

Grazioli L, Morana G, Kirchin MA and Schneider G: Accurate differentiation of focal nodular hyperplasia from hepatic adenoma at gadobenate dimeglumine-enhanced MR imaging: prospective study. Radiology. 236:166–177. 2005. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Sun J, Wang S, Chen W and Wu J: Gd‑EOB‑DTPA‑enhanced and diffusion‑weighted magnetic resonance findings in hepatic epithelioid angiomyolipoma: A case report. Oncol Lett 10: 1145-1148, 2015.
APA
Sun, J., Wang, S., Chen, W., & Wu, J. (2015). Gd‑EOB‑DTPA‑enhanced and diffusion‑weighted magnetic resonance findings in hepatic epithelioid angiomyolipoma: A case report. Oncology Letters, 10, 1145-1148. https://doi.org/10.3892/ol.2015.3368
MLA
Sun, J., Wang, S., Chen, W., Wu, J."Gd‑EOB‑DTPA‑enhanced and diffusion‑weighted magnetic resonance findings in hepatic epithelioid angiomyolipoma: A case report". Oncology Letters 10.2 (2015): 1145-1148.
Chicago
Sun, J., Wang, S., Chen, W., Wu, J."Gd‑EOB‑DTPA‑enhanced and diffusion‑weighted magnetic resonance findings in hepatic epithelioid angiomyolipoma: A case report". Oncology Letters 10, no. 2 (2015): 1145-1148. https://doi.org/10.3892/ol.2015.3368
Copy and paste a formatted citation
x
Spandidos Publications style
Sun J, Wang S, Chen W and Wu J: Gd‑EOB‑DTPA‑enhanced and diffusion‑weighted magnetic resonance findings in hepatic epithelioid angiomyolipoma: A case report. Oncol Lett 10: 1145-1148, 2015.
APA
Sun, J., Wang, S., Chen, W., & Wu, J. (2015). Gd‑EOB‑DTPA‑enhanced and diffusion‑weighted magnetic resonance findings in hepatic epithelioid angiomyolipoma: A case report. Oncology Letters, 10, 1145-1148. https://doi.org/10.3892/ol.2015.3368
MLA
Sun, J., Wang, S., Chen, W., Wu, J."Gd‑EOB‑DTPA‑enhanced and diffusion‑weighted magnetic resonance findings in hepatic epithelioid angiomyolipoma: A case report". Oncology Letters 10.2 (2015): 1145-1148.
Chicago
Sun, J., Wang, S., Chen, W., Wu, J."Gd‑EOB‑DTPA‑enhanced and diffusion‑weighted magnetic resonance findings in hepatic epithelioid angiomyolipoma: A case report". Oncology Letters 10, no. 2 (2015): 1145-1148. https://doi.org/10.3892/ol.2015.3368
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