Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies

  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
February-2016 Volume 11 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
February-2016 Volume 11 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Acute lymphocytic leukemia mimicking spondyloarthritis in an adolescent: A case report and review of the literature

  • Authors:
    • Danyi Xu
    • Guanhua Xu
    • Liqin Xu
    • Heng Cao
    • Bei Xu
    • Weiqian Chen
    • Chuanyin Sun
    • Lihuan Yue
    • Jin Lin

  • View Affiliations / Copyright

    Affiliations: Department of Rheumatology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China
  • Pages: 1143-1145
    |
    Published online on: December 11, 2015
       https://doi.org/10.3892/ol.2015.4026
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The present study describes the case of an 18-year-old adolescent male exhibiting acute lymphocytic leukemia (ALL), complicated by the onset of the symptom of sacroiliitis mimicking spondyloarthritis. Atypical features including an enlarged spleen, poor effects of non‑steroidal anti‑inflammatory drug therapy, low levels of hemoglobin, a low platelet count, a low neutrophil count and increased levels of monocytes, indicated the possibility of hematological malignancy. Bone marrow examination confirmed the diagnosis of ALL. The patient received chemotherapy and the symptoms were dramatically relieved. To the best of our knowledge, the current study reports the second published case of a patient with ALL presenting with sacroiliitis. Sacroiliitis as an onset manifestation of ALL may result in misdiagnosis, therefore, a differential diagnosis is essential when atypical features are present.
View Figures

Figure 1

Figure 2

View References

1 

Usalan C, Ozarslan E, Zengin N, Büyükaýk Y and Güllü YH: Acute lymphoblastic leukaemia presenting with arthritis in an adult patient. Postgrad Med J. 75:425–427. 1999. View Article : Google Scholar : PubMed/NCBI

2 

Jones OY, Spencer CH, Bowyer SL, Dent PB, Gottlieb BS and Rabinovich CE: A multicenter case control study on predictive factors distinguishing childhood leukemia from juvenile rheumatoid arthritis. Pediatrics. 117:e840–e844. 2006. View Article : Google Scholar : PubMed/NCBI

3 

Andras C, Csiki Z, Ponyi A, Illés A and Dankó K: Paraneoplastie rheumatic syndromes. Rheumatol Int. 26:376–382. 2006. View Article : Google Scholar : PubMed/NCBI

4 

Luzar MJ and Sharma HM: Leukemia and arthritis: Including reports on light immunofluorescent, and electron microscopy of the synovium. J Rheumatol. 10:132–135. 1983.PubMed/NCBI

5 

Taillan B, Leyge JF, Fuzibet JG, Nectoux F, Ziegler G and Dujardin P: Knee arthritis revealing acute leukemia in a patient with rheumatoid arthritis. Clin Rheumatol. 10:76–77. 1991. View Article : Google Scholar : PubMed/NCBI

6 

Hoshino T, Matsushima T, Saitoh Y, Yamane A, Takizawa M, Irisawa H, Saitoh T, Handa H, Tsukamoto N, Karasawa M, et al: Sacroiliitis as an initial manifestation of acute myelogenous leukemia. Int J Hematol. 84:421–424. 2006. View Article : Google Scholar : PubMed/NCBI

7 

Moghadam A, Talebi-Taher M and Dehghan A: Sacroiliitis as an initial presentation of acute lymphoblastic leukemia. Acta Clin Belg. 65:197–199. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Dougados M and Baeten D: Spondyloarthritis. Lancet. 377:2127–2137. 2011. View Article : Google Scholar : PubMed/NCBI

9 

Appelbaum FR: The acute leukemias. Wyngaarden JB, Smith LH and Bennett JC: Cecil Textbook of Medicine. 1:(19th). (Philadelphia, PA, USA). WB Saunders Company. 44–949. 1992.

10 

Marwaha RK, Kulkarni KP, Bansal D and Trehan A: Acute lymphoblastic leukemia masquerading as juvenile rheumatoid arthritis, Diagnostic pitfall and association with survival. Ann Hematol. 89:249–254. 2010. View Article : Google Scholar : PubMed/NCBI

11 

Acree SC, Pullarkat ST, Quismorio FP Jr, Mian SR and Brynes RK: Adult leukemic synovitis is associated with leukemia of monocytic differentiation. J Clin Rheumatol. 17:130–134. 2011. View Article : Google Scholar : PubMed/NCBI

12 

Jones OY, Spencer CH, Bowyer SL, Dent PB, Gottlieb BS and Rabinovich CE: A multicenter case-control study on predictive factors distinguishing childhood leukemia from juvenile rheumatoid arthritis. Pediatrics. 117:e840–e844. 2006. View Article : Google Scholar : PubMed/NCBI

13 

Gupta D, Singh S, Suri D, Ahluwalia J, Das R and Varma N: Arthritic presentation of acute leukemia in children, Experience from a tertiary care centre in North India. Rheumatol Int. 30:767–770. 2010. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Xu D, Xu G, Xu L, Cao H, Xu B, Chen W, Sun C, Yue L and Lin J: Acute lymphocytic leukemia mimicking spondyloarthritis in an adolescent: A case report and review of the literature. Oncol Lett 11: 1143-1145, 2016.
APA
Xu, D., Xu, G., Xu, L., Cao, H., Xu, B., Chen, W. ... Lin, J. (2016). Acute lymphocytic leukemia mimicking spondyloarthritis in an adolescent: A case report and review of the literature. Oncology Letters, 11, 1143-1145. https://doi.org/10.3892/ol.2015.4026
MLA
Xu, D., Xu, G., Xu, L., Cao, H., Xu, B., Chen, W., Sun, C., Yue, L., Lin, J."Acute lymphocytic leukemia mimicking spondyloarthritis in an adolescent: A case report and review of the literature". Oncology Letters 11.2 (2016): 1143-1145.
Chicago
Xu, D., Xu, G., Xu, L., Cao, H., Xu, B., Chen, W., Sun, C., Yue, L., Lin, J."Acute lymphocytic leukemia mimicking spondyloarthritis in an adolescent: A case report and review of the literature". Oncology Letters 11, no. 2 (2016): 1143-1145. https://doi.org/10.3892/ol.2015.4026
Copy and paste a formatted citation
x
Spandidos Publications style
Xu D, Xu G, Xu L, Cao H, Xu B, Chen W, Sun C, Yue L and Lin J: Acute lymphocytic leukemia mimicking spondyloarthritis in an adolescent: A case report and review of the literature. Oncol Lett 11: 1143-1145, 2016.
APA
Xu, D., Xu, G., Xu, L., Cao, H., Xu, B., Chen, W. ... Lin, J. (2016). Acute lymphocytic leukemia mimicking spondyloarthritis in an adolescent: A case report and review of the literature. Oncology Letters, 11, 1143-1145. https://doi.org/10.3892/ol.2015.4026
MLA
Xu, D., Xu, G., Xu, L., Cao, H., Xu, B., Chen, W., Sun, C., Yue, L., Lin, J."Acute lymphocytic leukemia mimicking spondyloarthritis in an adolescent: A case report and review of the literature". Oncology Letters 11.2 (2016): 1143-1145.
Chicago
Xu, D., Xu, G., Xu, L., Cao, H., Xu, B., Chen, W., Sun, C., Yue, L., Lin, J."Acute lymphocytic leukemia mimicking spondyloarthritis in an adolescent: A case report and review of the literature". Oncology Letters 11, no. 2 (2016): 1143-1145. https://doi.org/10.3892/ol.2015.4026
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team