Surgical management of isolated retroperitoneal Castleman's disease: A case report

Xu,Jun; Zhou,Bo; Cao,Hua‑Li; Wang,Bo; Yan,Sheng; Zheng,Shu‑Sen

doi:10.3892/ol.2016.4177

Surgical management of isolated retroperitoneal Castleman's disease: A case report

Authors:
- Jun Xu
- Bo Zhou
- Hua‑Li Cao
- Bo Wang
- Sheng Yan
- Shu‑Sen Zheng
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Affiliations: Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, P.R. China, Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, P.R. China, Department of Pathology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, P.R. China
Published online on: February 2, 2016 https://doi.org/10.3892/ol.2016.4177
Pages: 2123-2126

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Abstract

Castleman's disease (CD) is an uncommon, poorly understood lymphoproliferative disease. Retroperitoneal forms may present as either a unicentric or multicentric disease. The present study reports the case of a 36‑year‑old man who was referred to the First Affiliated Hospital, School of Medicine, Zhejiang University (Hangzhou, China), for a detailed examination of an abdominal mass. The abdominal ultrasound and computed tomography scans revealed a solid mass localized in the region between segment 1 of the liver and the pancreas. An endosonography‑guided fine‑needle aspiration biopsy revealed chronic inflammation and lymphadenosis. The present study reports a rare case, in which the patient was treated with an exploratory laparotomy and resection. The retroperitoneal mass was pathologically diagnosed as CD of the hyaline vascular type. The patient was closely followed‑up for 11 months and is presently free of disease. In conclusion, the possibility of unicentric CD should be considered when facing a solid hypervascular retroperitoneal mass. A complete surgical resection may successfully treat the disease without an unnecessarily extensive resection for the unicentric type.

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1	El-Osta HE and Kurzrock R: Castleman's disease: From basic mechanisms to molecular therapeutics. Oncologist. 16:497–511. 2011. View Article : Google Scholar : PubMed/NCBI
2	Castleman B and Towne VW: Case records of the Massachusetts General Hospital; weekly clinicopathological exercises; founded by Richard C. Cabot. N Engl J Med. 251:396–400. 1954.PubMed/NCBI
3	Bucher P, Chassot G, Zufferey G, Ris F, Huber O and Morel P: Surgical management of abdominal and retroperitoneal Castleman's disease. World J Surg Oncol. 3:332005. View Article : Google Scholar : PubMed/NCBI
4	Fu L, Wang XL, Babu SR, Zhang Y, Su AP, Wang ZL, Hu T and Tian BL: Pancreatic Castleman's disease: Studies of three cases and a cumulative review of the literature. Indian J Surg. 75:34–38. 2013. View Article : Google Scholar : PubMed/NCBI
5	Keller AR, Hochholzer L and Castleman B: Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer. 29:670–683. 1972. View Article : Google Scholar : PubMed/NCBI
6	Zhang J, Song N, Liu B, Hua L, Wang Z, Yin C and Zhang W: A case report of unusual retroperitoneal Castleman's disease in an old woman. Urol Int. 89:369–372. 2012. View Article : Google Scholar : PubMed/NCBI
7	Flendrig JA and Schillings PHM: Benign giant lymphoma: The clinical signs and symptoms. Folia Med Neerl. 12:119–120. 1969.
8	Seco JL, Velasco F, Manuel JS, Serrano SR, Tomas L and Velasco A: Retroperitoneal Castleman's disease. Surgery. 112:850–855. 1992.PubMed/NCBI
9	Gaba AR, Stein RS, Sweet DL and Variakojis D: Multicentric giant lymph node hyperplasia. Am J Clin Pathol. 69:86–90. 1978.PubMed/NCBI
10	Frizzera G, Banks PM, Massarelli G and Rosai J: A systemic lymphoproliferative disorder with morphologic features of Castleman's disease. Pathological findings in 15 patients. Am J Surg Pathol. 7:211–231. 1983. View Article : Google Scholar : PubMed/NCBI
11	Talat N and Schulte KM: Castleman's disease: Systematic analysis of 416 patients from the literature. Oncologist. 16:1316–1324. 2011. View Article : Google Scholar : PubMed/NCBI
12	Shahidi H, Myers JL and Kvale PA: Castleman's disease. Mayo Clin Proc. 70:969–977. 1995. View Article : Google Scholar : PubMed/NCBI
13	Gracia-Ramos AE, del Cruz-Domínguez MP and Vera-Lastra OL: Multicentric hyaline vascular Castleman's disease. A POEMS type variant. Rev Med Inst Mex Seguro Soc. 51:464–467. 2013.(In Spanish). PubMed/NCBI
14	Andhavarapu S and Jiang L: POEMS syndrome and Castleman disease. Blood. 122:1592013. View Article : Google Scholar : PubMed/NCBI
15	Franco V: Report of a case of localized Castleman's disease with progression to malignant lymphoma. Am J Clin Pathol. 100:707–708. 1993.PubMed/NCBI
16	Park J, Lee JE, Kim M, Lim J, Kim Y, Han K, Park G, Jung YH, Roh SY and Hong YS: Discordant lymphocyte-depleted classical Hodgkin's and peripheral T-cell lymphoma arising in a patient 11 years after diagnosis of multicentric Castleman's disease. Int J Hematol. 98:114–121. 2013. View Article : Google Scholar : PubMed/NCBI
17	Rao S, Ramesh A, Rajkumar A, Arcot R and Kuruvilla S: Persistent or recurrent Castleman's disease - Look out for a lurking lymphoma! Indian J Med Paediatr Oncol. 32:162–164. 2011. View Article : Google Scholar : PubMed/NCBI
18	Ozkan H, Tolunay S, Gözü O and Ozer ZG: Giant lymphoid hamartoma of mediastinum (Castleman's disease). Thorac Cardiovasc Surg. 38:321–323. 1990. View Article : Google Scholar : PubMed/NCBI
19	Dossier A, Meignin V, Fieschi C, Boutboul D, Oksenhendler E and Galicier L: Human herpes virus 8-related Castleman disease in the absence of HIV infection. Clin Infect Dis. 56:833–842. 2013. View Article : Google Scholar : PubMed/NCBI
20	Oksenhendler E: HIV-associated multicentric Castleman disease. Curr Opin HIV AIDS. 4:16–21. 2009. View Article : Google Scholar : PubMed/NCBI
21	Yoshizaki K, Matsuda T, Nishimoto N, Kuritani T, Taeho L, Aozasa K, Nakahata T, Kawai H, Tagoh H, Komori T, et al: Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease. Blood. 74:1360–1367. 1989.PubMed/NCBI
22	Suthaus J, Stuhlmann-Laeisz C, Tompkins VS, Rosean TR, Klapper W, Tosato G, Janz S, Scheller J and Rose-John S: HHV-8-encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice. Blood. 119:5173–5181. 2012. View Article : Google Scholar : PubMed/NCBI
23	Poole PS, Chang EY and Santillan CS: Case: 172 Retroperitoneal Castleman disease (hyaline vascular type). Radiology. 260:601–605. 2011. View Article : Google Scholar : PubMed/NCBI
24	Miyoshi H, Mimura S, Nomura T, Tani J, Morishita A, Kobara H, Mori H, Yoneyama H, Deguchi A, Himoto T, et al: A rare case of hyaline-type Castleman disease in the liver. World J Hepatol. 5:404–408. 2013. View Article : Google Scholar : PubMed/NCBI
25	Otto M, Wieprzowski L, Dzwonkowski J and Ziarkiewicz-Wróblewska B: Castleman's disease - an unusual indication for laparoscopic adrenalectomy. Wideochir Inne Tech Maloinwazyjne. 7:50–54. 2012.PubMed/NCBI
26	Kim MS, Ju JK and Kim Y: Surgical management of unicentric castleman's disease in the abdomen. Ann Coloproctol. 30:97–100. 2014. View Article : Google Scholar : PubMed/NCBI
27	Bo P, Junhua Z, Qiruo G and Hong L: A case report of retroperitoneal Castleman disease. Can Urol Assoc J. 3:E14–E16. 2009.PubMed/NCBI
28	Park JB, Hwang JH, Kim H, Choe HS, Kim YK, Kim HB and Bang SM: Castleman disease presenting with jaundice: A case with the multicentric hyaline vascular variant. Korean J Intern Med. 22:113–117. 2007. View Article : Google Scholar : PubMed/NCBI
29	Rhee KH, Lee SS and Huh JR: Endoscopic ultrasonography-guided trucut biopsy for the preoperative diagnosis of peripancreatic Castleman's disease: A case report. World J Gastroenterol. 14:2115–2117. 2008. View Article : Google Scholar : PubMed/NCBI
30	Cecka F, Ferko A, Jon B, Subrt Z, Kasparova P and Repak R: Pancreatic Castleman disease treated with laparoscopic distal pancreatectomy. Hepatobiliary Pancreat Dis Int. 12:332–334. 2013. View Article : Google Scholar : PubMed/NCBI