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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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March-2016 Volume 11 Issue 3

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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report Open Access

Giant and high-risk gastrointestinal stromal tumor in the abdomino-pelvic cavity: A case report

  • Authors:
    • Yujiao Wang
    • Jie Peng
    • Jinbai Huang
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Clinical Medical College of Yangtze University, Jingzhou, Hubei 434025, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2035-2038
    |
    Published online on: February 8, 2016
       https://doi.org/10.3892/ol.2016.4196
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Abstract

Gastrointestinal stromal tumors (GISTs) are benign mesenchymal tumors of the gastrointestinal tract. The clinical presentations of patients with GIST are variable and may be non‑specific. The current study reports the case of a 66-year-old man that presented with a gradual enlargement of the abdomen, emaciation, hyperhidrosis and frequent and urgent micturition. A computed tomography (CT) scan of the abdomen revealed a large, heterogeneous, low density mass that occupied the entire abdomino-pelvic cavity. Magnetic resonance imaging (MRI) identified a high signal intensity on the T2 weighted image and an intermediate signal intensity on the T1 weighted image. A contrast enhanced CT scan and MRI demonstrated the uptake of contrast material. A biopsy revealed that the tumor was composed of spindle cells, and immunohistochemical analysis identified the presence of mast/stem cell growth factor receptors. Together, these results lead to a diagnosis of GIST. The clinical findings, imaging modalities and pathological studies suggested that the GIST was a large and high‑risk tumor located in the abdomino‑pelvic cavity. The final surgical results confirmed these findings. Following conservative treatment with imatnib (400 mg, daily) for 6 months, the tumor became smaller and was suitable for surgery, which the patient received in December 2014. The final surgery confirmed the high‑risk GIST. Subsequent to the surgery, the patient was recommended to continue the use of imatnib with regular CT or MRI reexaminations every 3 months, which are planned to continue for 3 years.
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Copy and paste a formatted citation
Spandidos Publications style
Wang Y, Peng J and Huang J: Giant and high-risk gastrointestinal stromal tumor in the abdomino-pelvic cavity: A case report. Oncol Lett 11: 2035-2038, 2016.
APA
Wang, Y., Peng, J., & Huang, J. (2016). Giant and high-risk gastrointestinal stromal tumor in the abdomino-pelvic cavity: A case report. Oncology Letters, 11, 2035-2038. https://doi.org/10.3892/ol.2016.4196
MLA
Wang, Y., Peng, J., Huang, J."Giant and high-risk gastrointestinal stromal tumor in the abdomino-pelvic cavity: A case report". Oncology Letters 11.3 (2016): 2035-2038.
Chicago
Wang, Y., Peng, J., Huang, J."Giant and high-risk gastrointestinal stromal tumor in the abdomino-pelvic cavity: A case report". Oncology Letters 11, no. 3 (2016): 2035-2038. https://doi.org/10.3892/ol.2016.4196
Copy and paste a formatted citation
x
Spandidos Publications style
Wang Y, Peng J and Huang J: Giant and high-risk gastrointestinal stromal tumor in the abdomino-pelvic cavity: A case report. Oncol Lett 11: 2035-2038, 2016.
APA
Wang, Y., Peng, J., & Huang, J. (2016). Giant and high-risk gastrointestinal stromal tumor in the abdomino-pelvic cavity: A case report. Oncology Letters, 11, 2035-2038. https://doi.org/10.3892/ol.2016.4196
MLA
Wang, Y., Peng, J., Huang, J."Giant and high-risk gastrointestinal stromal tumor in the abdomino-pelvic cavity: A case report". Oncology Letters 11.3 (2016): 2035-2038.
Chicago
Wang, Y., Peng, J., Huang, J."Giant and high-risk gastrointestinal stromal tumor in the abdomino-pelvic cavity: A case report". Oncology Letters 11, no. 3 (2016): 2035-2038. https://doi.org/10.3892/ol.2016.4196
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