Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
March-2016 Volume 11 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
March-2016 Volume 11 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Stereotactic radiotherapy for the treatment of lung cancer with a giant left atrial tumor thrombus: A case report and literature review

  • Authors:
    • Yong Li
    • Jinrong Lou
    • Shujun Qiu
    • Yutian Guo
    • Mianshun Pan
  • View Affiliations / Copyright

    Affiliations: Center of Radiation Oncology, Wujing Hospital, Shanghai 201103, P.R. China, Department of Cardiology, Jiading Central Hospital, Shanghai 201800, P.R. China
  • Pages: 2229-2232
    |
    Published online on: February 9, 2016
       https://doi.org/10.3892/ol.2016.4215
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Lung cancer presenting with a giant atrial tumor thrombus is particularly rare. Surgical resection, aided by a cardiopulmonary bypass, is the standard treatment of choice if there is no distant metastasis. However, this form of surgery carries a high risk, with the subsequent patient prognosis being extremely poor. The current study describes the case of a 52‑year‑old man presenting with left lung squamous cell carcinoma that had extended into the left atrium. The patient was treated with stereotactic radiotherapy, and regarding the atrial disease, a complete response was achieved within 12 months. The present case demonstrates that stereotactic radiotherapy may be a beneficial palliative treatment for patients with stage IV lung cancer invading the left atrium.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Lee P and Kishan AU: Radiotherapy is effective for a primary lung cancer invading the left atrium. BMJ Case Rep. 2012:2012.

2 

Takahashi K, Furuse M, Hanaoka H, Yamada T, Mineta M, Ono H, Nagasawa K and Aburano T: Pulmonary vein and left atrial invasion by lung cancer: Assessment by breath-hold gadolinium-enhanced three-dimensional MR angiography. J Comput Assist Tomogr. 24:557–561. 2000. View Article : Google Scholar : PubMed/NCBI

3 

Kodama K, Doi O and Tatsuta M: Unusual extension of lung cancer into the left atrium via the pulmonary vein. Int Surg. 75:22–26. 1990.PubMed/NCBI

4 

Sadat U, Noor N, See TC and Varty K: Peripheral arterial ischemia by a primary lung tumour invading left atrium. Lung Cancer. 57:237–239. 2007. View Article : Google Scholar : PubMed/NCBI

5 

Koh TW: Invasion of lung mesenchymal chondrosarcoma into the left atrium via the pulmonary vein detected on transoesophageal echocardiography. Eur J Echocardiogr. 12:5562011. View Article : Google Scholar : PubMed/NCBI

6 

Woodring JH, Bognar B and van Wyk CS: Metastatic chondrosarcoma to the lung with extension into the left atrium via invasion of the pulmonary veins: Presentation as embolic cerebral infarction. Clin Imaging. 26:338–341. 2002. View Article : Google Scholar : PubMed/NCBI

7 

Shimizu J, Ikeda C, Arano Y, Adachi I, Morishita M, Yamaguchi S, Ishikawa N, Watanabe G and Minato H: Advanced lung cancer invading the left atrium, treated with pneumonectomy combined with left atrium resection under cardiopulmonary bypass. Ann Thorac Cardiovasc Surg. 16:286–290. 2010.PubMed/NCBI

8 

Tsim S, O'Dowd CA, Milroy R and Davidson S: Staging of non-small cell lung cancer (NSCLC): A review. Respir Med. 104:1767–1774. 2010. View Article : Google Scholar : PubMed/NCBI

9 

Sengül C, Sünbül A, Ozveren O and Değertekin M: Case images: Squamous cell lung cancer metastasis in the left atrium: An interesting case with cardiac images. Turk Kardiyol Dern Ars. 40:6542012. View Article : Google Scholar : PubMed/NCBI

10 

Ueda K, Kaneda Y, Sakano H, Tanaka T, Saito K and Hamono K: Successful treatment of intracardiac progression and metachronous multiple brain metastases from primary lung cancer. Jpn J Thorac Cardiovasc Surg. 54:168–170. 2006. View Article : Google Scholar : PubMed/NCBI

11 

Kim JH, Jung JY, Park Y, Hwang SI, Jung CS, Lee SH and Yoo CW: Non-small cell lung cancer initially presenting with intracardiac metastasis. Korean J Intern Med. 20:86–89. 2005. View Article : Google Scholar : PubMed/NCBI

12 

Asaad K, Sadaba JR and Nair RU: Intracardiac extension of squamous cell carcinoma of lung. Eur J Cardiothorac Surg. 24:6402003. View Article : Google Scholar : PubMed/NCBI

13 

Costache VS, Lantuejoul S, Stoica S, Fluttaz A, Hacini R and Brichon PY: Giant intracardiac neoplasic thrombus of a large cell neuroendocrine carcinoma of the lung. Cardiovasc Pathol. 19:e85–e87. 2010. View Article : Google Scholar : PubMed/NCBI

14 

Lin MT, Ku SC, Wu MZ and Yu CJ: Intracardiac extension of lung cancer via the pulmonary vein. Thorax. 63:11222008. View Article : Google Scholar : PubMed/NCBI

15 

Brandt RR, Rubin J and Reeder GS: Intracardiac extension of a lung tumor causing left ventricular inflow obstruction. J Am Soc Echocardiogr. 8:930–933. 1995. View Article : Google Scholar : PubMed/NCBI

16 

Ma Q, Liu D, Liu P, Chen J, Xie Z and D'Amico TA: Extensive invasion of the left atrium by lung cancer. Ann Thorac Surg. 96:685–687. 2013. View Article : Google Scholar : PubMed/NCBI

17 

Alexandrescu C, Civaia F and Dor V: Tumor thrombus in right atrium from lung adenocarcinoma. Ann Thorac Surg. 87:e11–e12. 2009. View Article : Google Scholar : PubMed/NCBI

18 

Ucak A, Inan K, Onan B, Temizkan V, Alp I and Yilmaz AT: Free-floating tumor thrombus in the left atrium associated with non-small cell lung cancer. J Card Surg. 24:686–689. 2009. View Article : Google Scholar : PubMed/NCBI

19 

Dogan A, Icli A, Arslan A, Varol E and Ozaydin M: Metastatic atrial sarcoma extending from the lung into the left atrium via a pulmonary vein. Exp Clin Cardiol. 17:77–78. 2012.PubMed/NCBI

20 

Khan N, Golzar J, Smith NL and Movahed A: Intracardiac extension of a large cell undifferentiated carcinoma of lung. Heart. 91:5122005. View Article : Google Scholar : PubMed/NCBI

21 

Yokouchi H, Kodama K, Higashiyama M, Takami K, Kobayashi T, Takami H, Nakamura S and Horai T: Successful removal of a primitive neuroectodermal tumor in the lung with gross extension into the left atrium. Thorac Cardiovasc Surg. 47:257–259. 1999. View Article : Google Scholar : PubMed/NCBI

22 

Thomas GM, Panicot-Dubois L, Lacroix R, Dignat-George F, Lombardo D and Dubois C: Cancer cell-derived microparticles bearing P-selectin glycoprotein ligand 1 accelerate thrombus formation in vivo. J Exp Med. 206:1913–1927. 2009. View Article : Google Scholar : PubMed/NCBI

23 

DiPerna CA and Wood DE: Surgical management of T3 and T4 lung cancer. Clin Cancer Res. 11:5038s–5044s. 2005. View Article : Google Scholar : PubMed/NCBI

24 

Fukuse T, Wada H and Hitomi S: Extended operation for non-small cell lung cancer invading great vessels and left atrium. Eur J Cardiothorac Surg. 11:664–669. 1997. View Article : Google Scholar : PubMed/NCBI

25 

Remouchamps VM, Vicini FA, Sharpe MB, Kestin LL, Martinez AA and Wong JW: Significant reductions in heart and lung doses using deep inspiration breath hold with active breathing control and intensity-modulated radiation therapy for patients treated with locoregional breast irradiation. Int J Radiat Oncol Biol Phys. 55:392–406. 2003. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Li Y, Lou J, Qiu S, Guo Y and Pan M: Stereotactic radiotherapy for the treatment of lung cancer with a giant left atrial tumor thrombus: A case report and literature review. Oncol Lett 11: 2229-2232, 2016.
APA
Li, Y., Lou, J., Qiu, S., Guo, Y., & Pan, M. (2016). Stereotactic radiotherapy for the treatment of lung cancer with a giant left atrial tumor thrombus: A case report and literature review. Oncology Letters, 11, 2229-2232. https://doi.org/10.3892/ol.2016.4215
MLA
Li, Y., Lou, J., Qiu, S., Guo, Y., Pan, M."Stereotactic radiotherapy for the treatment of lung cancer with a giant left atrial tumor thrombus: A case report and literature review". Oncology Letters 11.3 (2016): 2229-2232.
Chicago
Li, Y., Lou, J., Qiu, S., Guo, Y., Pan, M."Stereotactic radiotherapy for the treatment of lung cancer with a giant left atrial tumor thrombus: A case report and literature review". Oncology Letters 11, no. 3 (2016): 2229-2232. https://doi.org/10.3892/ol.2016.4215
Copy and paste a formatted citation
x
Spandidos Publications style
Li Y, Lou J, Qiu S, Guo Y and Pan M: Stereotactic radiotherapy for the treatment of lung cancer with a giant left atrial tumor thrombus: A case report and literature review. Oncol Lett 11: 2229-2232, 2016.
APA
Li, Y., Lou, J., Qiu, S., Guo, Y., & Pan, M. (2016). Stereotactic radiotherapy for the treatment of lung cancer with a giant left atrial tumor thrombus: A case report and literature review. Oncology Letters, 11, 2229-2232. https://doi.org/10.3892/ol.2016.4215
MLA
Li, Y., Lou, J., Qiu, S., Guo, Y., Pan, M."Stereotactic radiotherapy for the treatment of lung cancer with a giant left atrial tumor thrombus: A case report and literature review". Oncology Letters 11.3 (2016): 2229-2232.
Chicago
Li, Y., Lou, J., Qiu, S., Guo, Y., Pan, M."Stereotactic radiotherapy for the treatment of lung cancer with a giant left atrial tumor thrombus: A case report and literature review". Oncology Letters 11, no. 3 (2016): 2229-2232. https://doi.org/10.3892/ol.2016.4215
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team