Open Access

Primary diffuse large B-cell lymphoma of the dura with skull and scalp involvement: A case report and brief review of the literature

  • Authors:
    • Zhong‑Wen Lv
    • Kai‑Liang Cheng
    • Hong‑Ji Tian
    • Xue‑Mei Han
  • View Affiliations

  • Published online on: April 18, 2016     https://doi.org/10.3892/ol.2016.4455
  • Pages: 3583-3588
  • Copyright: © Lv et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Primary dural lymphoma (PDL) refers to a lymphoma with epidural or subdural involvement and is a rare subtype of primary central nervous system lymphoma. Diffuse large B‑cell lymphoma (DLBCL) presenting as PDL is extremely rare. The present study reports a case of PDL with skull and scalp involvement in a 56‑year‑old man. Magnetic resonance imaging (MRI) revealed that the tumor was located under the right parietal inner plate and was attached to the dura mater. Following contrast‑enhanced MRI, markedly enhanced tumor signals were observed, and mild homogeneous enhancement was observed in the diploë and soft tissues under the scalp, near the parietal bone. Under general anesthesia, the patient underwent craniotomy and tumor resection. The postoperative pathological diagnosis was DLBCL. Tumors were additionally identified inside the skull and subcutaneous tissues. The patient was administered chemotherapy postoperatively, and the prognosis subsequent to the 4‑year follow‑up was favorable. Primary malignant lymphoma should be considered in the differential diagnosis of scalp masses and meningeal lesions. Early diagnosis and individualized treatment is closely associated with a favorable outcome.
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June-2016
Volume 11 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Lv ZW, Cheng KL, Tian HJ and Han XM: Primary diffuse large B-cell lymphoma of the dura with skull and scalp involvement: A case report and brief review of the literature. Oncol Lett 11: 3583-3588, 2016
APA
Lv, Z., Cheng, K., Tian, H., & Han, X. (2016). Primary diffuse large B-cell lymphoma of the dura with skull and scalp involvement: A case report and brief review of the literature. Oncology Letters, 11, 3583-3588. https://doi.org/10.3892/ol.2016.4455
MLA
Lv, Z., Cheng, K., Tian, H., Han, X."Primary diffuse large B-cell lymphoma of the dura with skull and scalp involvement: A case report and brief review of the literature". Oncology Letters 11.6 (2016): 3583-3588.
Chicago
Lv, Z., Cheng, K., Tian, H., Han, X."Primary diffuse large B-cell lymphoma of the dura with skull and scalp involvement: A case report and brief review of the literature". Oncology Letters 11, no. 6 (2016): 3583-3588. https://doi.org/10.3892/ol.2016.4455