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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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June-2016 Volume 11 Issue 6

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report

Recurrent renal cell carcinoma manifesting as a large intrathoracic fibrotic mass: A case report

  • Authors:
    • Ji Hyun Kim
    • Jae Hoon Jeong
    • Sung‑Hyun Park
    • Jin Seon Jeong
    • Young-Joon Ryu
    • Seo‑Young Song

  • View Affiliations / Copyright

    Affiliations: Department of Internal Medicine, Kangwon National University Hospital, Kangwon National University, School of Medicine, Chuncheon, Gangwon 200‑947, Republic of Korea
  • Pages: 3835-3838
    |
    Published online on: April 19, 2016
       https://doi.org/10.3892/ol.2016.4460
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Abstract

Renal cell carcinomas (RCCs) have a strong tendency to metastasize, and the most common sites are the lungs, bones and liver. Late recurrence is another feature of the RCC, with lesions appearing ≥10 years after surgical treatment. However, fibrosis has rarely been associated with the disease. The present study reports a case of recurrent RCC that manifested as a fibrotic mass within the thorax. A 48‑year‑old man presented with dyspnea that had persisted for 3 days. The patient had undergone a right radical nephrectomy for stage II clear cell carcinoma of the kidney 6 years previously. The patient was a current smoker, with a smoking history of 20 pack‑years. Chest radiography showed pleural effusion in the right thorax with an egg‑sized mass shadow within the right upper lung (RUL) field. Computed tomography (CT) showed a main mass, 7 cm in diameter, within the RUL, with heterogeneous enhancement and multiple nodules of various sizes in the lungs, suggestive of primary lung cancer or metastatic RCC. A CT-guided percutaneous needle aspiration biopsy was obtained from the main mass, but histology revealed dense fibrous tissue without any malignant cells. Positron emission tomography‑CT demonstrated an irregular hypermetabolic RUL mass, with a standardized uptake value (SUV) of 5.0, along the right pleura, and small pulmonary nodules (SUV, 2.0). Ultrasound‑guided biopsy was attempted for a smaller hypermetabolic pleural nodule and the result was clear cell adenocarcinoma, consistent with the previous renal histology. The present study describes the case, along with a review of the relevant literature.
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Copy and paste a formatted citation
Spandidos Publications style
Kim JH, Jeong JH, Park SH, Jeong JS, Ryu Y and Song SY: Recurrent renal cell carcinoma manifesting as a large intrathoracic fibrotic mass: A case report. Oncol Lett 11: 3835-3838, 2016.
APA
Kim, J.H., Jeong, J.H., Park, S., Jeong, J.S., Ryu, Y., & Song, S. (2016). Recurrent renal cell carcinoma manifesting as a large intrathoracic fibrotic mass: A case report. Oncology Letters, 11, 3835-3838. https://doi.org/10.3892/ol.2016.4460
MLA
Kim, J. H., Jeong, J. H., Park, S., Jeong, J. S., Ryu, Y., Song, S."Recurrent renal cell carcinoma manifesting as a large intrathoracic fibrotic mass: A case report". Oncology Letters 11.6 (2016): 3835-3838.
Chicago
Kim, J. H., Jeong, J. H., Park, S., Jeong, J. S., Ryu, Y., Song, S."Recurrent renal cell carcinoma manifesting as a large intrathoracic fibrotic mass: A case report". Oncology Letters 11, no. 6 (2016): 3835-3838. https://doi.org/10.3892/ol.2016.4460
Copy and paste a formatted citation
x
Spandidos Publications style
Kim JH, Jeong JH, Park SH, Jeong JS, Ryu Y and Song SY: Recurrent renal cell carcinoma manifesting as a large intrathoracic fibrotic mass: A case report. Oncol Lett 11: 3835-3838, 2016.
APA
Kim, J.H., Jeong, J.H., Park, S., Jeong, J.S., Ryu, Y., & Song, S. (2016). Recurrent renal cell carcinoma manifesting as a large intrathoracic fibrotic mass: A case report. Oncology Letters, 11, 3835-3838. https://doi.org/10.3892/ol.2016.4460
MLA
Kim, J. H., Jeong, J. H., Park, S., Jeong, J. S., Ryu, Y., Song, S."Recurrent renal cell carcinoma manifesting as a large intrathoracic fibrotic mass: A case report". Oncology Letters 11.6 (2016): 3835-3838.
Chicago
Kim, J. H., Jeong, J. H., Park, S., Jeong, J. S., Ryu, Y., Song, S."Recurrent renal cell carcinoma manifesting as a large intrathoracic fibrotic mass: A case report". Oncology Letters 11, no. 6 (2016): 3835-3838. https://doi.org/10.3892/ol.2016.4460
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