Oligodendroglioma metastasis to the bone marrow mimicking multiple myeloma: A case report

Jian,Yuan; Gao,Wen; Wu,Yin; Li,Yanchen; Zhang,Yong; Yang,Guangzhong; Chen,Wenming

doi:10.3892/ol.2016.4568

July-2016 Volume 12 Issue 1

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July-2016 Volume 12 Issue 1

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Case Report

Oligodendroglioma metastasis to the bone marrow mimicking multiple myeloma: A case report

Authors:
- Yuan Jian
- Wen Gao
- Yin Wu
- Yanchen Li
- Yong Zhang
- Guangzhong Yang
- Wenming Chen
View Affiliations / Copyright

Affiliations: Department of Hematology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China, Department of Hematology, Beijing Luhe Hospital, Capital Medical University, Beijing 101100, P.R. China
Pages: 351-355
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Published online on: May 13, 2016

https://doi.org/10.3892/ol.2016.4568
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Abstract

The present study reports a case of a 59-year-old male suffering from oligodendroglioma that metastasized to the bone marrow (BM). The metastasis was detected 5 years after craniotomy was performed for the resection of the primary tumor; however, it manifested as multiple myeloma (MM)‑like bone lesions, a small M component and myeloma cell‑like morphology in the BM. A brain magnetic resonance imaging scan was performed; evidence from the previously performed oligodendroglioma resection was observed on the scan, but there were no significant findings, which made the diagnosis particularly challenging. The patient exhibited no response to the multiple combination therapies administered targeting MM and oligodendroglioma, and subsequently developed epilepsy and pneumonia, prior to succumbing to multiple organ failure. Among the various tumor types involving the central nervous system, oligodendroglioma is the least likely to metastasize; thus, distant metastases from brain oligodendrogliomas are extremely rare. To the best of our knowledge, this is the first case of metastatic oligodendroglioma presenting with typical MM‑like symptoms and without any recurrence in the brain.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Oligodendroglioma metastasis to the bone marrow mimicking multiple myeloma: A case report

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