Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
July-2016 Volume 12 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
July-2016 Volume 12 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Considerations arising from requests from patients for a bilateral mastectomy who are eligible for breast‑conserving surgery: Factors weighing for and against performing the operation

  • Authors:
    • Alessandro Fancellu
  • View Affiliations / Copyright

    Affiliations: Department of Clinical and Experimental Medicine, Unit of General Surgery 2‑Clinica Chirurgica, University of Sassari, I‑07100 Sassari, Italy
  • Pages: 764-766
    |
    Published online on: May 30, 2016
       https://doi.org/10.3892/ol.2016.4641
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Rates of mastectomy and contralateral prophylactic mastectomy (CPM) are increasing in patients with unilateral breast cancer who would be candidates for receiving breast‑conserving surgery, according to recent studies. One reason for this finding is the entitlement of patients to choose to undergo a bilateral mastectomy as a surgery option. The present case report details the case of a 52‑year‑old woman, eligible for breast conservation, who had no high risk of developing a contralateral breast cancer, but who asked for a bilateral mastectomy and immediate reconstruction instead of breast‑conserving surgery. The request for a bilateral mastectomy was declined on the basis that it would be unnecessary for the patient, and an excessive intervention; the patient subsequently obtained an independent second opinion, and she underwent a bilateral mastectomy with implant reconstruction prior to receiving wound care and follow‑up at our institution. At follow‑up 1 year later, the patient complained of sensations of general discomfort, sexual difficulties and a loss of sensation in the nipples. On the basis of the clinical outcomes of the bilateral mastectomy and the patient's experience of the operation, the present case study highlights a need for surgeons to clearly inform patients presenting with unilateral breast cancer about the attendant risks and real benefits of bilateral mastectomy, in order to reach a mutual decision in terms of health care that is not fuelled by anxiety or an overestimation of the risk of developing secondary cancer. Bilateral mastectomy should be attentively evaluated as an option only in patients with a higher‑than‑average risk of developing contralateral breast cancer.
View Figures

Figure 1

Figure 2

View References

1 

Tracy MS, Rosenberg SM, Dominici L and Partridge AH: Contralateral prophylactic mastectomy in women with breast cancer: Trends, predictors, and areas for future research. Breast Cancer Res Treat. 140:447–452. 2013. View Article : Google Scholar : PubMed/NCBI

2 

Stucky CC, Gray RJ, Wasif N, Dueck AC and Pockaj BA: Increase in contralateral prophylactic mastectomy: Echoes of a bygone era? Surgical trends for unilateral breast cancer. Ann Surg Oncol. 17(Suppl 3): S330–S337. 2010. View Article : Google Scholar

3 

Kummerow KL, Du L, Penson DF, Shyr Y and Hooks MA: Nationwide trends in mastectomy for early-stage breast cancer. JAMA Surg. 150:9–16. 2015. View Article : Google Scholar : PubMed/NCBI

4 

Adkisson CD, Bagaria SP, Parker AS, Bray JM, Gibson T, Thomas CS, Heckman MG and McLaughlin SA: Which eligible breast conservation patients choose mastectomy in the setting of newly diagnosed breast cancer? Ann Surg Oncol. 19:1129–1136. 2012. View Article : Google Scholar : PubMed/NCBI

5 

Portschy PR and Tuttle TM: Rise of mastectomy. J Surg Oncol. 107:563–564. 2013. View Article : Google Scholar : PubMed/NCBI

6 

Soran A, Kamali Polat A, Johnson R and McGuire KP: Increasing trend of contralateral prophylactic mastectomy: What are the factors behind this phenomenon? Surgeon. 12:316–322. 2014. View Article : Google Scholar : PubMed/NCBI

7 

Janssen S, Holz-Sapra E, Rades D, Moser A and Studer G: Nipple-sparing mastectomy in breast cancer patients: The role of adjuvant radiotherapy (Review). Oncol Lett. 9:2435–2441. 2015.PubMed/NCBI

8 

Fancellu A, Soro D, Castiglia P, Marras V, Melis M, Cottu P, Cherchi A, Spanu A, Mulas S, Pusceddu C, et al: Usefulness of magnetic resonance in patients with invasive cancer eligible for breast conservation: A comparative study. Clin Breast Cancer. 14:114–121. 2014. View Article : Google Scholar : PubMed/NCBI

9 

Fancellu A, Turner RM, Dixon JM, Pinna A, Cottu P and Houssami N: Meta-analysis of the effect of preoperative breast MRI on the surgical management of ductal carcinoma in situ. Br J Surg. 102:883–893. 2015. View Article : Google Scholar : PubMed/NCBI

10 

Agarwal S, Agarwal S, Neumayer L and Agarwal JP: Therapeutic nipple-sparing mastectomy: Trends based on a national cancer database. Am J Surg. 208:93–98. 2014. View Article : Google Scholar : PubMed/NCBI

11 

King TA, Sakr R, Patil S, Gurevich I, Stempel M, Sampson M and Morrow M: Clinical management factors contribute to the decision for contralateral prophylactic mastectomy. J Clin Oncol. 29:2158–2164. 2011. View Article : Google Scholar : PubMed/NCBI

12 

King TA, Gurevich I, Sakr R, Patil S, Stempel M and Morrow M: Occult malignancy in patients undergoing contralateral prophylactic mastectomy. Ann Surg. 254:2–7. 2011. View Article : Google Scholar : PubMed/NCBI

13 

Verhoog LC, Brekelmans CT, Seynaeve C, van den Bosch LM, Dahmen G, van Geel AN, Tilanus-Linthorst MM, Bartels CC, Wagner A, van den Ouweland A, et al: Survival and tumour characteristics of breast cancer patients with germline mutations of BRCA1. Lancet. 351:316–321. 1998. View Article : Google Scholar : PubMed/NCBI

14 

Rosenberg SM, Sepucha K, Ruddy KJ, Tamimi RM, Gelber S, Meyer ME, Schapira L, Come SE, Borges VF, Golshan M, et al: Local therapy decision-making and contralateral prophylactic mastectomy in young women with early-stage breast cancer. Ann Surg Oncol. 22:3809–3815. 2015. View Article : Google Scholar : PubMed/NCBI

15 

Chung A, Huynh K, Lawrence C, Sim MS and Giuliano A: Comparison of patient characteristics and outcomes of contralateral prophylactic mastectomy and unilateral total mastectomy in breast cancer patients. Ann Surg Oncol. 19:2600–2606. 2012. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Fancellu A: Considerations arising from requests from patients for a bilateral mastectomy who are eligible for breast‑conserving surgery: Factors weighing for and against performing the operation. Oncol Lett 12: 764-766, 2016.
APA
Fancellu, A. (2016). Considerations arising from requests from patients for a bilateral mastectomy who are eligible for breast‑conserving surgery: Factors weighing for and against performing the operation. Oncology Letters, 12, 764-766. https://doi.org/10.3892/ol.2016.4641
MLA
Fancellu, A."Considerations arising from requests from patients for a bilateral mastectomy who are eligible for breast‑conserving surgery: Factors weighing for and against performing the operation". Oncology Letters 12.1 (2016): 764-766.
Chicago
Fancellu, A."Considerations arising from requests from patients for a bilateral mastectomy who are eligible for breast‑conserving surgery: Factors weighing for and against performing the operation". Oncology Letters 12, no. 1 (2016): 764-766. https://doi.org/10.3892/ol.2016.4641
Copy and paste a formatted citation
x
Spandidos Publications style
Fancellu A: Considerations arising from requests from patients for a bilateral mastectomy who are eligible for breast‑conserving surgery: Factors weighing for and against performing the operation. Oncol Lett 12: 764-766, 2016.
APA
Fancellu, A. (2016). Considerations arising from requests from patients for a bilateral mastectomy who are eligible for breast‑conserving surgery: Factors weighing for and against performing the operation. Oncology Letters, 12, 764-766. https://doi.org/10.3892/ol.2016.4641
MLA
Fancellu, A."Considerations arising from requests from patients for a bilateral mastectomy who are eligible for breast‑conserving surgery: Factors weighing for and against performing the operation". Oncology Letters 12.1 (2016): 764-766.
Chicago
Fancellu, A."Considerations arising from requests from patients for a bilateral mastectomy who are eligible for breast‑conserving surgery: Factors weighing for and against performing the operation". Oncology Letters 12, no. 1 (2016): 764-766. https://doi.org/10.3892/ol.2016.4641
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team