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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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November-2016 Volume 12 Issue 5

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Case Report

Conversion of aspergilloma to chronic necrotizing pulmonary aspergillosis following treatment with sunitinib: A case report

  • Authors:
    • Yeon Wook Kim
    • Hyun Woo Lee
    • Jaeyoung Cho
    • Han‑Sol Choi
    • Jungsil Lee
    • Sung Soo Park
    • Eun Young Heo
    • Kwang Nam Jin
    • Deog Kyeom Kim

  • View Affiliations / Copyright

    Affiliations: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, Department of Radiology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea
  • Pages: 3472-3474
    |
    Published online on: August 26, 2016
       https://doi.org/10.3892/ol.2016.5052
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Abstract

Semi-invasive or invasive aspergillosis occurring following chemotherapy with sunitinib is a rare condition with unknown incidence and prognosis. Here, we report a case involving a 59‑year‑old male who had a history of underlying stable aspergilloma and was newly diagnosed with metastatic renal cell carcinoma. Following surgical resection for renal cell carcinoma and adjuvant chemotherapy with sunitinib for 8 months, the patient presented with hemoptysis. Chest computed tomography revealed an increased soft tissue mass and air crescent sign of the underlying aspergilloma, combined with consolidation and bronchial artery hypertrophy around the lesion. The patient underwent bronchoscopy with a biopsy of the lesion and was eventually diagnosed with chronic necrotizing pulmonary aspergillosis, which had progressed from the underlying stable aspergilloma. This case highlights the fact that clinicians should be aware of the risk of opportunistic conversion from stable aspergilloma to invasive fungal infections in patients undergoing sunitinib treatment.
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Copy and paste a formatted citation
Spandidos Publications style
Kim YW, Lee HW, Cho J, Choi HS, Lee J, Park SS, Heo EY, Jin KN and Kim DK: Conversion of aspergilloma to chronic necrotizing pulmonary aspergillosis following treatment with sunitinib: A case report. Oncol Lett 12: 3472-3474, 2016.
APA
Kim, Y.W., Lee, H.W., Cho, J., Choi, H., Lee, J., Park, S.S. ... Kim, D.K. (2016). Conversion of aspergilloma to chronic necrotizing pulmonary aspergillosis following treatment with sunitinib: A case report. Oncology Letters, 12, 3472-3474. https://doi.org/10.3892/ol.2016.5052
MLA
Kim, Y. W., Lee, H. W., Cho, J., Choi, H., Lee, J., Park, S. S., Heo, E. Y., Jin, K. N., Kim, D. K."Conversion of aspergilloma to chronic necrotizing pulmonary aspergillosis following treatment with sunitinib: A case report". Oncology Letters 12.5 (2016): 3472-3474.
Chicago
Kim, Y. W., Lee, H. W., Cho, J., Choi, H., Lee, J., Park, S. S., Heo, E. Y., Jin, K. N., Kim, D. K."Conversion of aspergilloma to chronic necrotizing pulmonary aspergillosis following treatment with sunitinib: A case report". Oncology Letters 12, no. 5 (2016): 3472-3474. https://doi.org/10.3892/ol.2016.5052
Copy and paste a formatted citation
x
Spandidos Publications style
Kim YW, Lee HW, Cho J, Choi HS, Lee J, Park SS, Heo EY, Jin KN and Kim DK: Conversion of aspergilloma to chronic necrotizing pulmonary aspergillosis following treatment with sunitinib: A case report. Oncol Lett 12: 3472-3474, 2016.
APA
Kim, Y.W., Lee, H.W., Cho, J., Choi, H., Lee, J., Park, S.S. ... Kim, D.K. (2016). Conversion of aspergilloma to chronic necrotizing pulmonary aspergillosis following treatment with sunitinib: A case report. Oncology Letters, 12, 3472-3474. https://doi.org/10.3892/ol.2016.5052
MLA
Kim, Y. W., Lee, H. W., Cho, J., Choi, H., Lee, J., Park, S. S., Heo, E. Y., Jin, K. N., Kim, D. K."Conversion of aspergilloma to chronic necrotizing pulmonary aspergillosis following treatment with sunitinib: A case report". Oncology Letters 12.5 (2016): 3472-3474.
Chicago
Kim, Y. W., Lee, H. W., Cho, J., Choi, H., Lee, J., Park, S. S., Heo, E. Y., Jin, K. N., Kim, D. K."Conversion of aspergilloma to chronic necrotizing pulmonary aspergillosis following treatment with sunitinib: A case report". Oncology Letters 12, no. 5 (2016): 3472-3474. https://doi.org/10.3892/ol.2016.5052
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