Optical lymph node detection system: A practical device to assist lymph node location in neck resection specimens

Wang,Yujia; Pu,Yumei; Ni,Yanhong; Wang,Zhiyong; Huang,Xiaofeng; Sun,Guowen; Hu,Qingang

doi:10.3892/ol.2018.7973

Optical lymph node detection system: A practical device to assist lymph node location in neck resection specimens

Authors:
- Yujia Wang
- Yumei Pu
- Yanhong Ni
- Zhiyong Wang
- Xiaofeng Huang
- Guowen Sun
- Qingang Hu
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Affiliations: Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210008, P.R. China, Department of Central Laboratory, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210008, P.R. China, Department of Oral Pathology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210008, P.R. China
Published online on: February 7, 2018 https://doi.org/10.3892/ol.2018.7973
Pages: 5306-5310

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Abstract

The status of lymph node (LN) metastasis, including the number and location of positive LNs, is a significant prognostic factor for oral squamous cell carcinoma (OSCC). Therefore, knowing the number and location of positive LNs is essential for prognosis. However, surgeons often have difficulty locating LNs. In the present study a practical device to improve the location of LNs in neck resection specimens was intoduced: the optical lymph nodes detection system (OLNDS). With the assistance of the OLNDS LNs were easier to locate and a significantly higher number of LNs were identified (P=0.006). The false detection rate was also significantly reduced compared with the traditional method (P=0.0034). The OLNDS was observed to be a valuable adjunct to the traditional method and may be useful for studying the value of LN metastasis in OSCC prognosis.

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