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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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April-2018 Volume 15 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Article

Optical lymph node detection system: A practical device to assist lymph node location in neck resection specimens

  • Authors:
    • Yujia Wang
    • Yumei Pu
    • Yanhong Ni
    • Zhiyong Wang
    • Xiaofeng Huang
    • Guowen Sun
    • Qingang Hu
  • View Affiliations / Copyright

    Affiliations: Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210008, P.R. China, Department of Central Laboratory, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210008, P.R. China, Department of Oral Pathology, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210008, P.R. China
  • Pages: 5306-5310
    |
    Published online on: February 7, 2018
       https://doi.org/10.3892/ol.2018.7973
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Abstract

The status of lymph node (LN) metastasis, including the number and location of positive LNs, is a significant prognostic factor for oral squamous cell carcinoma (OSCC). Therefore, knowing the number and location of positive LNs is essential for prognosis. However, surgeons often have difficulty locating LNs. In the present study a practical device to improve the location of LNs in neck resection specimens was intoduced: the optical lymph nodes detection system (OLNDS). With the assistance of the OLNDS LNs were easier to locate and a significantly higher number of LNs were identified (P=0.006). The false detection rate was also significantly reduced compared with the traditional method (P=0.0034). The OLNDS was observed to be a valuable adjunct to the traditional method and may be useful for studying the value of LN metastasis in OSCC prognosis.
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1 

Parkin DM, Bray F, Ferlay J and Pisani P: Global cancer statistics, 2002. CA Cancer J Clin. 55:74–108. 2005. View Article : Google Scholar : PubMed/NCBI

2 

Bagan JV and Scully C: Recent advances in oral oncology 2007: Epidemiology, aetiopathogenesis, diagnosis and prognostication. Oral Oncol. 44:103–108. 2008. View Article : Google Scholar : PubMed/NCBI

3 

Woolgar JA, Triantafyllou A, Lewis JS Jr, Hunt J, Williams MD, Takes RP, Thompson LD, Slootweg PJ, Devaney KO and Ferlito A: Prognostic biological features in neck dissection specimens. Eur Arch Otorhinolaryngol. 270:1581–1592. 2013. View Article : Google Scholar : PubMed/NCBI

4 

Liao CT, Hsueh C, Lee LY, Lin CY, Fan KH, Wang HM, Huang SF, Chen IH, Kang CJ, Ng SH, et al: Neck dissection field and lymph node density predict prognosis in patients with oral cavity cancer and pathological node metastases treated with adjuvant therapy. Oral Oncol. 48:329–336. 2012. View Article : Google Scholar : PubMed/NCBI

5 

Shingaki S, Takada M, Sasai K, Bibi R, Kobayashi T, Nomura T and Saito C: Impact of lymph node metastasis on the pattern of failure and survival in oral carcinomas. Am J Surg. 185:278–284. 2003. View Article : Google Scholar : PubMed/NCBI

6 

Woolgar JA: Detailed topography of cervical lymph-note metastases from oral squamous cell carcinoma. Int J Oral Maxillofac Surg. 26:3–9. 1997. View Article : Google Scholar : PubMed/NCBI

7 

Yuasa-Nakagawa K, Shibuya H, Yoshimura R, Miura M, Watanabe H, Kishimoto S and Omura K: Cervical lymph node metastasis from early-stage squamous cell carcinoma of the oral tongue. Acta Otolaryngol. 133:544–551. 2013. View Article : Google Scholar : PubMed/NCBI

8 

Amar A, Chedid HM, Rapoport A, Cernea CR, Dedivitis RA, Curioni OA and Brandão LG: Prognostic significance of the number of lymph nodes in elective neck dissection for tongue and mouth floor cancers. Braz J Otorhinolaryngol. 78:22–26. 2012. View Article : Google Scholar : PubMed/NCBI

9 

Patel SG, Amit M, Yen TC, Liao CT, Chaturvedi P, Agarwal JP, Kowalski LP, Ebrahimi A, Clark JR, Cernea CR, et al: Lymph node density in oral cavity cancer: Results of the international consortium for outcomes research. Br J Cancer. 109:2087–2095. 2013. View Article : Google Scholar : PubMed/NCBI

10 

Ampil FL, Caldito G and Ghali GE: Can the lymph node ratio predict outcome in head and neck cancer with single metastasis positive-node? Oral Oncol. 50:e18–e20. 2014. View Article : Google Scholar : PubMed/NCBI

11 

Liao CT, Wang HM, Chang JT, Ng SH, Hsueh C, Lee LY, Lin CH, Chen IH, Huang SF and Yen TC: Analysis of risk factors for distant metastases in squamous cell carcinoma of the oral cavity. Cancer. 110:1501–1508. 2007. View Article : Google Scholar : PubMed/NCBI

12 

Shibuya Y, Hasegawa T, Akashi M, Shigeta T, Minamikawa T and Komori T: Oral squamous cell carcinoma with multiple neck metastases-cases with more than ten pathologically positive lymph nodes in the unilateral side. J Oral Maxillofac Surg. 71:793–797. 2013. View Article : Google Scholar : PubMed/NCBI

13 

Ebrahimi A, Gil Z, Amit M, Yen TC, Liao CT, Chaturvedi P, Agarwal JP, Kowalski LP, Kohler HF, Kreppel M, et al: The prognosis of N2b and N2c lymph node disease in oral squamous cell carcinoma is determined by the number of metastatic lymph nodes rather than laterality: Evidence to support a revision of the American Joint Committee on Cancer staging system. Cancer. 120:1968–1974. 2014. View Article : Google Scholar : PubMed/NCBI

14 

Sayed SI, Sharma S, Rane P, Vaishampayan S, Talole S, Chaturvedi P, Chaukar D, Deshmukh A, Agarwal JP and D'Cruz AK: Can metastatic lymph node ratio (LNR) predict survival in oral cavity cancer patients? J Surg Oncol. 108:256–263. 2013. View Article : Google Scholar : PubMed/NCBI

15 

Huang SH and O'Sullivan B: Overview of the 8th edition TNM classification for head and neck cancer. Curr Treat Options Oncol. 18:402017. View Article : Google Scholar : PubMed/NCBI

16 

Robbins KT, Clayman G, Levine PA, Medina J, Sessions R, Shaha A, Som P and Wolf GT; American Head and Neck Society, ; American Academy of Otolaryngology-Head and Neck Surgery, : Neck dissection classification update: Revisions proposed by the American Head and Neck Society and the American Academy of Otolaryngology-Head and Neck Surgery. Arch Otolaryngol Head Neck Surg. 128:751–758. 2002. View Article : Google Scholar : PubMed/NCBI

17 

Leong SP and Tseng WW: Micrometastatic cancer cells in lymph nodes, bone marrow, and blood: Clinical significance and biologic implications. CA Cancer J Clin. 64:195–206. 2014. View Article : Google Scholar : PubMed/NCBI

18 

Balch CM, Soong SJ, Gershenwald JE, Thompson JF, Reintgen DS, Cascinelli N, Urist M, McMasters KM, Ross MI, Kirkwood JM, et al: Prognostic factors analysis of 17,600 melanoma patients: Validation of the american joint committee on cancer melanoma staging system. J Clin Oncol. 19:3622–3634. 2001. View Article : Google Scholar : PubMed/NCBI

19 

Leong SP, Nakakura EK, Pollock R, Choti MA, Morton DL, Henner WD, Lal A, Pillai R, Clark OH and Cady B: Unique patterns of metastases in common and rare types of malignancy. J Surg Oncol. 103:607–614. 2011. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Wang Y, Pu Y, Ni Y, Wang Z, Huang X, Sun G and Hu Q: Optical lymph node detection system: A practical device to assist lymph node location in neck resection specimens. Oncol Lett 15: 5306-5310, 2018.
APA
Wang, Y., Pu, Y., Ni, Y., Wang, Z., Huang, X., Sun, G., & Hu, Q. (2018). Optical lymph node detection system: A practical device to assist lymph node location in neck resection specimens. Oncology Letters, 15, 5306-5310. https://doi.org/10.3892/ol.2018.7973
MLA
Wang, Y., Pu, Y., Ni, Y., Wang, Z., Huang, X., Sun, G., Hu, Q."Optical lymph node detection system: A practical device to assist lymph node location in neck resection specimens". Oncology Letters 15.4 (2018): 5306-5310.
Chicago
Wang, Y., Pu, Y., Ni, Y., Wang, Z., Huang, X., Sun, G., Hu, Q."Optical lymph node detection system: A practical device to assist lymph node location in neck resection specimens". Oncology Letters 15, no. 4 (2018): 5306-5310. https://doi.org/10.3892/ol.2018.7973
Copy and paste a formatted citation
x
Spandidos Publications style
Wang Y, Pu Y, Ni Y, Wang Z, Huang X, Sun G and Hu Q: Optical lymph node detection system: A practical device to assist lymph node location in neck resection specimens. Oncol Lett 15: 5306-5310, 2018.
APA
Wang, Y., Pu, Y., Ni, Y., Wang, Z., Huang, X., Sun, G., & Hu, Q. (2018). Optical lymph node detection system: A practical device to assist lymph node location in neck resection specimens. Oncology Letters, 15, 5306-5310. https://doi.org/10.3892/ol.2018.7973
MLA
Wang, Y., Pu, Y., Ni, Y., Wang, Z., Huang, X., Sun, G., Hu, Q."Optical lymph node detection system: A practical device to assist lymph node location in neck resection specimens". Oncology Letters 15.4 (2018): 5306-5310.
Chicago
Wang, Y., Pu, Y., Ni, Y., Wang, Z., Huang, X., Sun, G., Hu, Q."Optical lymph node detection system: A practical device to assist lymph node location in neck resection specimens". Oncology Letters 15, no. 4 (2018): 5306-5310. https://doi.org/10.3892/ol.2018.7973
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