1
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
2
|
Gillen S, Schuster T, Meyer Zum
Büschenfelde C, Friess H and Kleeff J: Preoperative/neoadjuvant
therapy in pancreatic cancer: A systematic review and meta-analysis
of response and resection percentages. PLoS Med. 7:e10002672010.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2015. CA Cancer J Clin. 65:5–29. 2015. View Article : Google Scholar : PubMed/NCBI
|
4
|
Hidalgo M: Pancreatic cancer. N Engl J
Med. 362:1605–1617. 2010. View Article : Google Scholar : PubMed/NCBI
|
5
|
Neoptolemos JP, Stocken DD, Friess H,
Bassi C, Dunn JA, Hickey H, Beger H, Fernandez-Cruz L, Dervenis C,
Lacaine F, et al: A randomized trial of chemoradiotherapy and
chemotherapy after resection of pancreatic cancer. N Engl J Med.
350:1200–1210. 2004. View Article : Google Scholar : PubMed/NCBI
|
6
|
Tanaka M, Okazaki T, Suzuki H, Abbruzzese
JL and Li D: Association of multi-drug resistance gene
polymorphisms with pancreatic cancer outcome. Cancer. 117:744–751.
2011. View Article : Google Scholar : PubMed/NCBI
|
7
|
Polgar O and Bates SE: ABC transporters in
the balance: Is there a role in multidrug resistance? Biochem Soc
Trans. 33:241–245. 2005. View Article : Google Scholar : PubMed/NCBI
|
8
|
Douet V, Heller MB and Le Saux O: DNA
methylation and Sp1 binding determine the tissue-specific
transcriptional activity of the mouse Abcc6 promoter. Biochem
Biophys Res Commun. 354:66–71. 2007. View Article : Google Scholar : PubMed/NCBI
|
9
|
Bram EE, Stark M, Raz S and Assaraf YG:
Chemotherapeutic drug-induced ABCG2 promoter demethylation as a
novel mechanism of acquired multidrug resistance. Neoplasia.
11:1359–1370. 2009. View Article : Google Scholar : PubMed/NCBI
|
10
|
Gao P, Yang X, Xue YW, Zhang XF, Wang Y,
Liu WJ and Wu XJ: Promoter methylation of glutathione S-transferase
pi1 and multidrug resistance gene 1 in bronchioloalveolar carcinoma
and its correlation with DNA methyltransferase 1 expression.
Cancer. 115:3222–3232. 2009. View Article : Google Scholar : PubMed/NCBI
|
11
|
Pang L, Word B, Xu J, Wang H, Hammons G,
Huang SM and Lyn-Cook B: ATP-binding cassette genes genotype and
expression: A potential association with pancreatic cancer
development and chemoresistance? Gastroenterol Res Pract 2014.
4149312014.
|
12
|
Chen M, Xue X, Wang F, An Y, Tang D, Xu Y,
Wang H, Yuan Z, Gao W, Wei J, et al: Expression and promoter
methylation analysis of ATP-binding cassette genes in pancreatic
cancer. Oncol Rep. 27:265–269. 2012.PubMed/NCBI
|
13
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
14
|
Cascorbi I: Role of pharmacogenetics of
ATP-binding cassette transporters in the pharmacokinetics of drugs.
Pharmacol Ther. 112:457–473. 2006. View Article : Google Scholar : PubMed/NCBI
|
15
|
Suwa H, Ohshio G, Arao S, Imamura T,
Yamaki K, Manabe T, Imamura M, Hiai H and Fukumoto M:
Immunohistochemical localization of P-glycoprotein and expression
of the multidrug resistance-1 gene in human pancreatic cancer:
Relevance to indicator of better prognosis. Jpn J Cancer Res.
87:641–649. 1996. View Article : Google Scholar : PubMed/NCBI
|
16
|
Lu Z, Kleeff J, Shrikhande S, Zimmermann
T, Korc M, Friess H and Büchler MW: Expression of the
multidrug-resistance 1 (MDR1) gene and prognosis in human
pancreatic cancer. Pancreas. 21:240–247. 2000. View Article : Google Scholar : PubMed/NCBI
|
17
|
König J, Hartel M, Nies AT, Martignoni ME,
Guo J, Büchler MW, Friess H and Keppler D: Expression and
localization of human multidrug resistance protein (ABCC) family
members in pancreatic carcinoma. Int J Cancer. 115:359–367. 2005.
View Article : Google Scholar : PubMed/NCBI
|
18
|
Lee SH, Kim H, Hwang JH, Lee HS, Cho JY,
Yoon YS and Han HS: Breast cancer resistance protein expression is
associated with early recurrence and decreased survival in
resectable pancreatic cancer patients. Pathol Int. 62:167–175.
2012. View Article : Google Scholar : PubMed/NCBI
|
19
|
Wang F, Xue X, Wei J, An Y, Yao J, Cai H,
Wu J, Dai C, Qian Z, Xu Z and Miao Y: hsa-miR-520 h downregulates
ABCG2 in pancreatic cancer cells to inhibit migration, invasion,
and side populations. Br J Cancer. 103:567–574. 2010. View Article : Google Scholar : PubMed/NCBI
|
20
|
Hamada S, Satoh K, Hirota M, Kanno A,
Umino J, Ito H, Masamune A, Kikuta K, Kume K and Shimosegawa T: The
homeobox gene MSX2 determines chemosensitivity of pancreatic cancer
cells via the regulation of transporter gene ABCG2. J Cell Physiol.
227:729–738. 2012. View Article : Google Scholar : PubMed/NCBI
|
21
|
Olempska M, Eisenach PA, Ammerpohl O,
Ungefroren H, Fandrich F and Kalthoff H: Detection of tumor stem
cell markers in pancreatic carcinoma cell lines. Hepatobiliary
Pancreat Dis Int. 6:92–97. 2007.PubMed/NCBI
|
22
|
Miranda-Lorenzo I, Dorado J, Lonardo E,
Alcala S, Serrano AG, Clausell-Tormos J, Cioffi M, Megias D,
Zagorac S, Balic A, et al: Intracellular autofluorescence: A
biomarker for epithelial cancer stem cells. Nat Methods.
11:1161–1169. 2014. View Article : Google Scholar : PubMed/NCBI
|
23
|
Zhou J, Wang CY, Liu T, Wu B, Zhou F,
Xiong JX, Wu HS, Tao J, Zhao G, Yang M and Gou SM: Persistence of
side population cells with high drug efflux capacity in pancreatic
cancer. World J Gastroenterol. 14:925–930. 2008. View Article : Google Scholar : PubMed/NCBI
|
24
|
Bird AP and Wolffe AP: Methylation-induced
repression-belts, braces, and chromatin. Cell. 99:451–454. 1999.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Toyota M, Suzuki H, Yamashita T, Hirata K,
Imai K, Tokino T and Shinomura Y: Cancer epigenomics: Implications
of DNA methylation in personalized cancer therapy. Cancer Sci.
100:787–791. 2009. View Article : Google Scholar : PubMed/NCBI
|
26
|
Ding S, Gong BD, Yu J, Gu J, Zhang HY,
Shang ZB, Fei Q, Wang P and Zhu JD: Methylation profile of the
promoter CpG islands of 14 ‘drug-resistance’ genes in
hepatocellular carcinoma. World J Gastroenterol. 10:3433–3440.
2004. View Article : Google Scholar : PubMed/NCBI
|
27
|
Chekhun VF, Kulik GI, Yurchenko OV,
Tryndyak VP, Todor IN, Luniv LS, Tregubova NA, Pryzimirska TV,
Montgomery B, Rusetskaya NV and Pogribny IP: Role of DNA
hypomethylation in the development of the resistance to doxorubicin
in human MCF-7 breast adenocarcinoma cells. Cancer Lett. 231:87–93.
2006. View Article : Google Scholar : PubMed/NCBI
|
28
|
Tada Y, Wada M, Kuroiwa K, Kinugawa N,
Harada T, Nagayama J, Nakagawa M, Naito S and Kuwano M: MDR1 gene
overexpression and altered degree of methylation at the promoter
region in bladder cancer during chemotherapeutic treatment. Clin
Cancer Res. 6:4618–4627. 2000.PubMed/NCBI
|
29
|
Chen M, Xue X, Wang F, An Y, Tang D, Xu Y,
Wang H, Yuan Z, Gao W, Wei J, et al: Expression and promoter
methylation analysis of ATP-binding cassette genes in pancreatic
cancer. Oncol Rep. 27:265–269. 2012.PubMed/NCBI
|
30
|
Wray CJ, Ahmad SA, Matthews JB and Lowy
AM: Surgery for pancreatic cancer: Recent controversies and current
practice. Gastroenterology. 128:1626–1641. 2005. View Article : Google Scholar : PubMed/NCBI
|
31
|
Krishna NB, LaBundy JL, Saripalli S,
Safdar R and Agarwal B: Diagnostic value of EUS-FNA in patients
suspected of having pancreatic cancer with a focal lesion on CT
scan/MRI but without obstructive jaundice. Pancreas. 38:625–630.
2009. View Article : Google Scholar : PubMed/NCBI
|
32
|
Goymer P: Natural selection: The evolution
of cancer. Nature. 454:1046–1086. 2008. View Article : Google Scholar : PubMed/NCBI
|
33
|
Jiang Y, Qiu Y, Minn AJ and Zhang NR:
Assessing intratumor heterogeneity and tracking longitudinal and
spatial clonal evolutionary history by next-generation sequencing.
Proc Natl Acad Sci USA. 113:pp. E5528–E5537. 2016; View Article : Google Scholar : PubMed/NCBI
|
34
|
BLUEPRINT consortium, . Quantitative
comparison of DNA methylation assays for biomarker development and
clinical applications. Nat Biotechnol. 34:726–737. 2016. View Article : Google Scholar : PubMed/NCBI
|