|
1
|
Ugurlucan M, Caglar IM, Caglar FN, Ziyade
S, Karatepe O, Yildiz Y, Zencirci E, Ugurlucan FG, Arslan AH,
Korkmaz S, et al: Aspirin: From a historical perspective. Recent
Pat Cardiovasc Drug Discov. 7:71–76. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Vane JR, Flower RJ and Botting RM: History
of aspirin and its mechanism of action. Stroke. 21 12
Suppl:IV12–IV23. 1990.PubMed/NCBI
|
|
3
|
Wang S, Liu Z, Wang L and Zhang X:
NF-kappaB signaling pathway, inflammation and colorectal cancer.
Cell Mol Immunol. 6:327–334. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Menter DG and Dubois RN: Prostaglandins in
cancer cell adhesion, migration, and invasion. Int J Cell Biol.
2012:7234192012. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Kanaoka S, Yoshida K, Miura N, Sugimura H
and Kajimura M: Potential usefulness of detecting cyclooxygenase 2
messenger RNA in feces for colorectal cancer screening.
Gastroenterology. 127:422–427. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Fenwick SW, Toogood GJ, Lodge JP and Hull
MA: The effect of the selective cyclooxygenase-2 inhibitor
rofecoxib on human colorectal cancerliver metastases.
Gastroenterology. 125:716–729. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Krishnan K, Ruffin MT, Normolle D,
Shureiqi I, Burney K, Bailey J, Peters-Golden M, Rock CL, Boland CR
and Brenner DE: Colonic mucosal prostaglandin E2 and cyclooxygenase
expression before and after low aspirin doses in subjects at high
risk or at normal risk for colorectal cancer. Cancer Epidemiol
Biomarkers Prev. 10:447–453. 2001.PubMed/NCBI
|
|
8
|
Derynck R and Zhang YE: Smad-dependent and
Smad-independent pathways in TGF-beta family signaling. Nature.
425:577–584. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Moon CM, Kwon JH, Kim JS, Oh SH, Jin Lee
K, Park JJ, Pil Hong S, Cheon JH, Kim TI and Kim WH: Nonsteroidal
anti-inflammatory drugs suppress cancer stem cells via inhibiting
PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in
colorectal cancer. Int J Cancer. 134:519–529. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Vaish V, Tanwar L and Sanyal SN: The role
of NF-κB and PPARγ in experimentally induced colorectal cancer and
chemoprevention by cyclooxygenase-2 inhibitors. Tumour Biol.
31:427–436. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ishizaki T, Katsumata K, Tsuchida A, Wada
T, Mori Y, Hisada M, Kawakita H and Aoki T: Etodolac, a selective
cyclooxygenase-2 inhibitor, inhibits liver metastasis of colorectal
cancercells via the suppression of MMP-9 activity. Int J Mol Med.
17:357–362. 2006.PubMed/NCBI
|
|
12
|
Shureiqi I, Chen D, Lotan R, Yang P,
Newman RA, Fischer SM and Lippman SM: 15-Lipoxygenase-1 mediates
nonsteroidalanti-inflammatory drug-induced apoptosis independently
of cyclooxygenase-2 in colon cancer cells. Cancer Res.
60:6846–6850. 2000.PubMed/NCBI
|
|
13
|
Zhou X, Huang SY, Feng JX, Gao YY, Zhao L,
Lu J, Huang BQ and Zhang Y: SOX7 is involved in aspirin-mediated
growth inhibition of human colorectal cancer cells. World J
Gastroenterol. 17:4922–4927. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Blobe GC, Schiemann WP and Lodish HF: Role
of transforming growth factor beta in human disease. N Engl J Med.
342:1350–1358. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Govinden R and Bhoola KD: Genealogy,
expression, and cellular function of transforming growth
factor-beta. Pharmacol Ther. 98:257–265. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Sánchez-Capelo A: Dual role for TGF-beta1
in apoptosis. Cytokine Growth Factor Rev. 16:15–34. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Pierce DF Jr, Gorska AE, Chytil A, Meise
KS, Page DL, Coffey RJ Jr and Moses HL: Mammary tumor suppression
by transforming growth factor beta 1 transgene expression. Proc
Natl Acad Sci USA. 92:pp. 4254–4258. 1995; View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Chen L, Lu X, Zeng T, Chen Y, Chen Q, Wu
W, Yan X, Cai H, Zhang Z, Shao Q and Qin W: Enhancement of
DEN-induced liver tumourigenesis in hepatocyte-specific
Lass2-knockout mice coincident with upregulation of the
TGF-β1-Smad4-PAI-1 axis. Oncol Rep. 31:885–893. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Elmore S: Apoptosis: A review of
programmed death. Toxicol Pathol. 35:495–516. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Wang Y, Jiang M, Li Z, Wang J, Du C,
Yanyang L, Yu Y, Wang X, Zhang N, Zhao M, et al: Hypoxia and TGF-β1
lead to endostatin resistance by cooperatively increasing cancer
stem cellsin A549 transplantation tumors. Cell Biosci. 5:722015.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Yue W, Zheng X, Lin Y, Yang CS, Xu Q,
Carpizo D, Huang H, DiPaola RS and Tan XL: Metformin combined with
aspirin significantly inhibit pancreatic cancer cell growth in
vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and
Bcl-2. Oncotarget. 6:21208–21224. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Koseki T, Yamato K, Krajewski S, Reed JC,
Tsujimoto Y and Nishihara T: Activin A-induced apoptosis is
suppressed by BCL-2. FEBS Lett. 376:247–250. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Saltzman A, Munro R, Searfoss G, Franks C,
Jaye M and Ivashchenko Y: Transforming growth factor-beta-mediated
apoptosis in the Ramos B-lymphoma cell line is accompanied by
caspase activation and Bcl-XL downregulation. Exp Cell Res.
242:244–254. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Fukuchi Y, Kizaki M, Yamato K, Kawamura C,
Umezawa A, Hata Ji, Nishihara T and Ikeda Y: Mcl-1, an
early-induction molecule, modulates activin A-induced apoptosis and
differentiation of CML cells. Oncogene. 20:704–713. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Chen RH and Chang TY: Involvement of
caspase family proteases in transforming growth factor-beta-induced
apoptosis. Cell Growth Differ. 8:821–827. 1997.PubMed/NCBI
|
|
26
|
Boatright KM and Salvesen GS: Mechanisms
of caspase activation. Curr Opin Cell Biol. 15:725–731. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Riedl SJ and Shi Y: Molecular mechanisms
of caspase regulation during apoptosis. Nat Rev Mol Cell Biol.
5:897–907. 2004. View
Article : Google Scholar : PubMed/NCBI
|
|
28
|
Thornberry NA and Lazebnik Y: Caspases:
Enemies within. Science. 281:1312–1316. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Alnemri ES: Mammalian cell death
proteases: A family of highly conserved aspartate specific cysteine
proteases. J Cell Biochem. 64:33–42. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Han BH, DeMattos RB, Dugan LL, Kim-Han JS,
Brendza RP, Fryer JD, Kierson M, Cirrito J, Quick K, Harmony JA, et
al: Clusterin contributes to caspase-3-independent brain injury
following neonatal hypoxia-ischemia. Nat Med. 7:338–343. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Thompson CB: Apoptosis in the pathogenesis
and treatment of disease. Science. 267:1456–1462. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Kuhn P and Sarkar DK: Ethanol induces
apoptotic death of b-Endorphin neurons in the rat Hypothalamus by a
TGF-beta 1-dependent mechanism. Alcohol Clin Exp Res. 32:706–714.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Jänne PA and Mayer RJ: Chemoprevention of
colorectal cancer. N Engl J Med. 342:1960–1968. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Algra AM and Rothwell PM: Effects of
regular aspirin on long-term cancer incidence and metastasis: A
systematic comparison of evidence from observational studies versus
randomised trials. Lancet Oncol. 13:518–527. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Rothwell PM, Wilson CE, Elwin M, Norrving
B, Algra A, Warlow CP and Meade TW: Long-term effect of aspirin on
colorectal cancer incidence and mortality: 20-year follow-up of
five randomized trials. Lancet. 376:1741–1750. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Patrono C and Rocca B: Aspirin: promise
and resistance in the new millennium. Arterioscler Thromb Vasc
Biol. 28 Suppl:s25–s32. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Lai MY, Huang JA, Liang ZH, Jiang HX and
Tang GD: Mechanisms underlying aspirin-mediated growth inhibition
and apoptosis induction of cyclooxygenase-2 negative colon cancer
cell line SW480. World J Gastroenterol. 14:4227–4233. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Bos CL, Kodach LL, van den Brink GR, Diks
SH, van Santen MM, Richel DJ, Peppelenbosch MP and Hardwick JC:
Effect of aspirin on the Wnt/beta-catenin pathway is mediated via
protein phosphatase 2A. Oncogene. 25:6447–6456. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Martin S, Phillips DC, Szekely-Szucs K,
Elghazi L, Desmots F and Houghton JA: Cyclooxygenase-2 inhibition
sensitizes human colon carcinoma cells to TRAIL-induced apoptosis
through clustering of DR5 and concentrating death-inducing
signaling complex components into ceramide-enriched caveolae.
Cancer Res. 65:11447–11458. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Kim KM, Song JJ, An JY, Kwon YT and Lee
YJ: Pretreatment of acetylsalicylic acid promotes tumor necrosis
factor-related apoptosis-inducing ligand-induced apoptosis by
down-regulating BCL-2 gene expression. J Biol Chem.
280:41047–41056. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Johnstone RW, Ruefli AA and Lowe SW:
Apoptosis: A link between cancer genetics and chemotherapy. Cell.
108:153–164. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Chinnaiyan AM and Dixit VM: The cell-death
machine. Curr Biol. 6:555–562. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Kasibhatla S and Tseng B: Why target
apoptosis in cancer treatment? Mol Cancer Ther. 2:573–580.
2003.PubMed/NCBI
|
|
44
|
Makin G: Targeting apoptosis in cancer
chemotherapy. Expert Opin Ther Targets. 6:73–84. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Marx J: Cancer research.
Anti-inflammatories inhibit cancer growth-but how? Science.
291:581–582. 2001.PubMed/NCBI
|
|
46
|
Fujita T, Matsui M, Takaku K, Uetake H,
Ichikawa W, Taketo MM and Sugihara K: Size- and invasion-dependent
increase in cyclooxygenase 2 levels in human colorectal carcinomas.
Cancer Res. 58:4823–4826. 1998.PubMed/NCBI
|
|
47
|
Marnett LJ: Aspirin and the potential role
of prostaglandins in colon cancer. Cancer Res. 52:5575–5589.
1992.PubMed/NCBI
|
|
48
|
Hanif R, Pittas A, Feng Y, Koutsos MI,
Qiao L, Staiano-Coico L, Shiff SI and Rigas B: Effects of
nonsteroidal anti-inflammatory drugs onproliferation and on
induction of apoptosis in colon cancer cells by a
prostaglandin-independent pathway. Biochem Pharmacol. 52:237–245.
1996. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Thun MJ, Jacobs EJ and Patrono C: The role
of aspirin in cancer prevention. Nat Rev Clin Oncol. 9:259–267.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Sun Y, Chen J and Rigas B: Chemopreventive
agents induce oxidative stress in cancer cells leading to COX-2
overexpression and COX-2-independent cell death. Carcinogenesis.
30:93–100. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Shtivelband MI, Juneja HS, Lee S and Wu
KK: Aspirin and salicylate inhibit colon cancer medium- and
VEGF-induced endothelial tube formation: Correlation with
suppression of cyclooxygenase-2 expression. J ThrombHaemost.
1:2225–2233. 2003. View Article : Google Scholar
|
|
52
|
Tian Y, Ye Y, Gao W, Chen H, Song T, Wang
D, Mao X and Ren C: Aspirin promotes apoptosis in a murine model of
colorectal cancer by mechanisms involving downregulation of
IL-6-STAT3 signaling pathway. Int J Colorectal Dis. 26:13–22. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Pathi S, Jutooru I, Chadalapaka G, Nair V,
Lee SO and Safe S: Aspirin inhibits colon cancer cell and tumor
growth and downregulates specificity protein (Sp) transcription
factors. PLoS One. 7:e482082012. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Shureiqi I, Xu X, Chen D, Lotan R, Morris
JS, Fischer SM and Lippman SM: Nonsteroidal anti-inflammatory drugs
induce apoptosis in esophageal cancer cells by restoring
15-lipoxygenase-1 expression. Cancer Res. 61:4879–4884.
2001.PubMed/NCBI
|
|
55
|
Zhang Z and DuBois RN: Par-4, a
proapoptoticgene, is regulated by NSAIDs in human colon carcinoma
cells. Gastroenterol. 118:1012–1017. 2000. View Article : Google Scholar
|
|
56
|
Bellosillo B, Piqué M, Barragán M, Castaño
E, Villamor N, Colomer D, Montserrat E, Pons G and Gil J: Aspirin
and salicylate induce apoptosis and activation of caspases in
B-cell chronic lymphocytic leukaemia cells. Blood. 92:1406–1414.
1998.PubMed/NCBI
|
|
57
|
Schwenger P, Bellosta P, Vietor I,
Basilico C, Skolnik Y and Vilcek J: Sodium salicylate induces
apoptosis via p38 mitogen activated protein kinase but inhibits
tumour necrosis factor-induced c-Jun N-terminal
kinase/stress-activated protein kinase activation. Proc Natl Acad
Sci USA. 94:pp. 2869–2873. 1997; View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Chan TA, Morin PJ, Vogelstein B and
Kinzler KW: Mechanisms underlying non-steroidal anti-inflammatory
drug-mediated apoptosis. Proc Natl Acad Sci USA. 95:pp. 681–686.
1998; View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Zimmermann KC, Waterhouse NJ, Goldstein
JC, Schuler M and Green DR: Aspirin induces apoptosis through
release of cytochrome c from mitochondria. Neoplasia. 2:505–513.
2000. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Din FV, Valanciute A, Houde VP, Zibrova D,
Green KA, Sakamoto K, Alessi DR and Dunlop G: Aspirin inhibits mTOR
signaling, activates AMP-activated protein kinase, and induces
autophagy in colorectal cancer cells. Gastroenterology.
142:1504–1515.e3. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Takada Y, Bhardwaj A, Potdar P and
Aggarwal BB: Nonsteroidal anti-inflammatory agents differ in their
ability to suppress NF-kappaB activation, inhibition of expression
of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell
proliferation. Oncogene. 23:9247–9258. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Tozawa K, Sakurada S, Kohri K and Okamoto
T: Effects of anti-nuclear factor kappa B reagents in blocking
adhesion of human cancer cells to vascular endothelial cells.
Cancer Res. 55:4162–4167. 1995.PubMed/NCBI
|
|
63
|
Fujioka S, Sclabas GM, Schmidt C,
Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C and Chiao
PJ: Function of nuclear factor kappaB in pancreatic cancer
metastasis. Clin Cancer Res. 9:346–354. 2003.PubMed/NCBI
|
|
64
|
Lu L, Sun HC, Zhang W, Chai ZT, Zhu XD,
Kong LQ, Wang WQ, Zhang KZ, Zhang YY, Zhang QB, et al: Aspirin
minimized the pro-metastasis effect of sorafenib and improved
survival by up-regulating HTATIP2 in hepatocellular carcinoma. PLoS
One. 8:e650232013. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Hossain MA, Kim DH, Jang JY, Kang YJ, Yoon
JH, Moon JO, Chung HY, Kim GY, Choi YH, Copple BL and Kim ND:
Aspirin enhances doxorubicin-induced apoptosis and reduces tumor
growth in human hepatocellular carcinoma cells in vitro and in
vivo. Int J Oncol. 40:1636–1642. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Smith RD: Evidence for autocrine growth
inhibition of rat intestinal epithelial (RIE-1) cells by
transforming growth factor type-beta. Biochem Mol Biol Int.
35:1315–1321. 1995.PubMed/NCBI
|
|
67
|
Murray PA, Barrett-Lee P, Travers M,
Luqmani Y, Powles T and Coombes RC: The prognostic significance of
transforming growth factors in human breast cancer. Br J Cancer.
67:1408–1412. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Sun Y, Gao W, Zhao Y, Cao W, Liu Z, Cui G,
Tong L, Lei F and Tang B: Visualization and inhibition of
mitochondria-nuclear translocation of apoptosis inducing factor by
a graphene oxide-DNA nanosensor. Anal Chem. 89:4642–4647. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Oussaief L, Hippocrate A, Ramirez V,
Rampanou A, Zhang W, Meyers D, Cole P, Khelifa R and Joab I:
Phosphatidylinositol 3-kinase/Akt pathway targets acetylation of
Smad3 through Smad3/CREB-binding protein interaction: Contribution
to transforming growth factor beta1-induced Epstein-Barr virus
reactivation. J Biol Chem. 284:23912–23924. 2009. View Article : Google Scholar : PubMed/NCBI
|
