|
1
|
Torre LA, Siegel RL and Jemal A: Lung
cancer statistics. Adv Exp Med Biol. 893:1–19. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Molina JR, Yang P, Cassivi SD, Schild SE
and Adjei AA: Non-small cell lung cancer: Epidemiology, risk
factors, treatment, and survivorship. Mayo Clin Proc. 83:pp.
584–594. 2008; View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Huang CY, Ju DT, Chang CF, Muralidhar
Reddy P and Velmurugan BK: A review on the effects of current
chemotherapy drugs and natural agents in treating non-small cell
lung cancer. Biomedicine (Taipei). 7:232017. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Chen HS, Liu Y, Lin LQ, Zhao JL, Zhang CP,
Jin JC, Wang L, Bai MH, Wang YC, Liu M and Shen BZ:
Anti-proliferative effect of an extract of the root of Polygonum
multiflorum Thunb. On MCF-7 human breast cancer cells and the
possible mechanisms. Mol Med Rep. 4:1313–1319. 2011.PubMed/NCBI
|
|
5
|
Dickson MA and Schwartz GK: Development of
cell-cycle inhibitors for cancer therapy. Curr Oncol. 16:36–43.
2009.PubMed/NCBI
|
|
6
|
Giacinti C and Giordano A: RB and cell
cycle progression. Oncogene. 25:5220–5227. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Foster DA, Yellen P, Xu L and Saqcena M:
Regulation of G1 cell cycle progression: Distinguishing the
restriction point from a nutrient-sensing cell growth
checkpoint(s). Genes Cancer. 1:1124–1131. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Nita M and Grzybowski A: The role of the
reactive oxygen species and oxidative stress in the pathomechanism
of the age-related ocular diseases and other pathologies of the
anterior and posterior eye segments in adults. Oxid Med Cell
Longev. 2016:31647342016. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ray PD, Huang BW and Tsuji Y: Reactive
oxygen species (ROS) homeostasis and redox regulation in cellular
signaling. Cell Signal. 24:981–990. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Wang Z, Zhao X and Gong X: Costunolide
induces lung adenocarcinoma cell line A549 cells apoptosis through
ROS (reactive oxygen species)-mediated endoplasmic reticulum
stress. Cell Biol Int. 40:289–297. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Xiao W, Jiang Y, Men Q, Yuan L, Huang Z,
Liu T, Li W and Liu X: Tetrandrine induces G1/S cell cycle arrest
through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis
in vivo. Int J Oncol. 46:360–368. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Qi B, Zhang L, Zhang Z, Ouyang J and Huang
H: Effects of ginsenosides-Rb1 on exercise-induced oxidative stress
in forced swimming mice. Pharmacogn Mag. 10:458–463. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Li J, Zhong W, Wang W, Hu S, Yuan J, Zhang
B, Hu T and Song G: Ginsenoside metabolite compound K promotes
recovery of dextran sulfate sodium-induced colitis and inhibits
inflammatory responses by suppressing NF-κB activation. PLoS One.
9:e878102014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Chung KS, Cho SH, Shin JS, Kim DH, Choi
JH, Choi SY, Rhee YK, Hong HD and Lee KT: Ginsenoside Rh2 induces
cell cycle arrest and differentiation in human leukemia cells by
upregulating TGF-β expression. Carcinogenesis. 34:331–340. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Lee DG, Lee AY, Kim KT, Cho EJ and Lee S:
Novel dammarane-type triterpene saponins from Panax ginseng root.
Chem Pharm Bull (Tokyo). 63:927–934. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Plumb JA, Milroy R and Kaye SB: Effects of
the pH dependence of
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium
bromide-formazan absorption on chemosensitivity determined by a
novel tetrazolium-based assay. Cancer Res. 49:4435–4440.
1989.PubMed/NCBI
|
|
17
|
Choi JH and Lee KT: Costunolide-induced
apoptosis in human leukemia cells: Involvement of c-jun N-terminal
kinase activation. Biol Pharm Bull. 32:1803–1808. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Park EY, Kim JI, Leem DG, Shin JS, Kim KT,
Choi SY, Lee MH, Choi JH, Lee YS and Lee KT: Resveratrol analogue
(E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline
induces apoptosis via Fas-mediated pathway in HL-60 human leukemia
cells. Oncol Rep. 36:3577–3587. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Taya Y: RB kinases and RB-binding
proteins: New points of view. Trends Biochem Sci. 22:14–17. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Verbon EH, Post JA and Boonstra J: The
influence of reactive oxygen species on cell cycle progression in
mammalian cells. Gene. 511:1–6. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhang W and Liu HT: MAPK signal pathways
in the regulation of cell proliferation in mammalian cells. Cell
Res. 12:9–18. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Joyce D, Albanese C, Steer J, Fu M,
Bouzahzah B and Pestell RG: NF-kappaB and cell-cycle regulation:
The cyclin connection. Cytokine Growth Factor Rev. 12:73–90. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Abe H, Arichi S, Hayashi T and Odashima S:
Ultrastructural studies of Morris hepatoma cells reversely
transformed by ginsenosides. Experientia. 35:1647–1649. 1979.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kim HS, Lee EH, Ko SR, Choi KJ, Park JH
and Im DS: Effects of ginsenosides Rg3 and Rh2 on the proliferation
of prostate cancer cells. Arch Pharm Res. 27:429–435. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Cheng CC, Yang SM, Huang CY, Chen JC,
Chang WM and Hsu SL: Molecular mechanisms of ginsenoside
Rh2-mediated G1 growth arrest and apoptosis in human lung
adenocarcinoma A549 cells. Cancer Chemother Pharmacol. 55:531–540.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hwang HC and Clurman BE: Cyclin E in
normal and neoplastic cell cycles. Oncogene. 24:2776–2786. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Connell-Crowley L, Harper JW and Goodrich
DW: Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell
cycle arrest by site-specific phosphorylation. Mol Biol Cell.
8:287–301. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Schmidt M, Lu Y, Parant JM, Lozano G,
Bacher G, Beckers T and Fan Z: Differential roles of p21(Waf1) and
p27(Kip1) in modulating chemosensitivity and their possible
application in drug discovery studies. Mol Pharmacol. 60:900–906.
2001. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Lee KW, Kim HJ, Lee YS, Park HJ, Choi JW,
Ha J and Lee KT: Acteoside inhibits human promyelocytic HL-60
leukemia cell proliferation via inducing cell cycle arrest at G0/G1
phase and differentiation into monocyte. Carcinogenesis.
28:1928–1936. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Wang R, Zhang Q, Peng X, Zhou C, Zhong Y,
Chen X, Qiu Y, Jin M, Gong M and Kong D: Stellettin B induces G1
arrest, apoptosis and autophagy in human non-small cell lung cancer
A549 cells via blocking PI3K/Akt/mTOR pathway. Sci Rep.
6:270712016. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Chang MS, Lee SG and Rho HM:
Transcriptional activation of Cu/Zn superoxide dismutase and
catalase genes by panaxadiol ginsenosides extracted from Panax
ginseng. Phytother Res. 13:641–644. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Dhillon AS, Hagan S, Rath O and Kolch W:
MAP kinase signalling pathways in cancer. Oncogene. 26:3279–3290.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Roberts PJ and Der CJ: Targeting the
Raf-MEK-ERK mitogen-activated protein kinase cascade for the
treatment of cancer. Oncogene. 26:3291–3310. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wagner EF and Nebreda AR: Signal
integration by JNK and p38 MAPK pathways in cancer development. Nat
Rev Cancer. 9:537–549. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Gao JL, Lv GY, He BC, Zhang BQ, Zhang H,
Wang N, Wang CZ, Du W, Yuan CS and He TC: Ginseng saponin
metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting
multiple cancer signaling pathways. Oncol Rep. 30:292–298. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Jung SH, Woo MS, Kim SY, Kim WK, Hyun JW,
Kim EJ, Kim DH and Kim HS: Ginseng saponin metabolite suppresses
phorbol ester-induced matrix metalloproteinase-9 expression through
inhibition of activator protein-1 and mitogen-activated protein
kinase signaling pathways in human astroglioma cells. Int J Cancer.
118:490–497. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
An JJ, Shi KJ, Wei W, Hua FY, Ci YL, Jiang
Q, Li F, Wu P, Hui KY, Yang Y and Xu CM: The ROS/JNK/ATF2 pathway
mediates selenite-induced leukemia NB4 cell cycle arrest and
apoptosis in vitro and in vivo. Cell Death Dis. 4:e9732013.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Kaltschmidt B, Kaltschmidt C, Hehner SP,
Dröge W and Schmitz ML: Repression of NF-kappaB impairs HeLa cell
proliferation by functional interference with cell cycle checkpoint
regulators. Oncogene. 18:3213–3225. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Rajitha B, Belalcazar A, Nagaraju GP,
Shaib WL, Snyder JP, Shoji M, Pattnaik S, Alam A and El-Rayes BF:
Inhibition of NF-κB translocation by curcumin analogs induces G0/G1
arrest and downregulates thymidylate synthase in colorectal cancer.
Cancer Lett. 373:227–233. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Tran KQ, Tin AS and Firestone GL:
Artemisinin triggers a G1 cell cycle arrest of human Ishikawa
endometrial cancer cells and inhibits cyclin-dependent kinase-4
promoter activity and expression by disrupting nuclear factor-κB
transcriptional signaling. Anticancer Drugs. 25:270–281. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Kim SM, Lee SY, Cho JS, Son SM, Choi SS,
Yun YP, Yoo HS, Yoon DY, Oh KW, Han SB and Hong JT: Combination of
ginsenoside Rg3 with docetaxel enhances the susceptibility of
prostate cancer cells via inhibition of NF-kappaB. Eur J Pharmacol.
631:1–9. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Kim ND, Pokharel YR and Kang KW:
Ginsenoside Rd enhances glutathione levels in H4IIE cells via
NF-kappaB-dependent gamma-glutamylcysteine ligase induction.
Pharmazie. 62:933–936. 2007.PubMed/NCBI
|
