Comparison between open partial laryngectomy with tube‑free tracheostomy and total laryngectomy for hypopharyngeal cancer with cartilage invasion

Lien,Ching‑Feng; Wang,Chih‑Chun; Hwang,Tzer‑Zen; Liu,Ching‑Feng; Lin,Bor‑Shyh; Weng,Hsu‑Huei; Liu,Chih‑Yi

doi:10.3892/ol.2018.9298

Comparison between open partial laryngectomy with tube‑free tracheostomy and total laryngectomy for hypopharyngeal cancer with cartilage invasion

Authors:
- Ching‑Feng Lien
- Chih‑Chun Wang
- Tzer‑Zen Hwang
- Ching‑Feng Liu
- Bor‑Shyh Lin
- Hsu‑Huei Weng
- Chih‑Yi Liu
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Affiliations: Department of Otolaryngology, Head and Neck Surgery, E‑DA Hospital of I‑Shou University, Kaohsiung 82445, Taiwan, R.O.C., Graduate Institute of Medical Sciences, Chang Jung Christian University, Tainan 71101, Taiwan, R.O.C. , Institute of Imaging and Biomedical Photonics, National Chiao Tung University, Tainan 71150, Taiwan, R.O.C., Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan, R.O.C., Department of Nursing, E‑DA Hospital of I‑Shou University, Kaohsiung 82445, Taiwan, R.O.C.
Published online on: August 13, 2018 https://doi.org/10.3892/ol.2018.9298
Pages: 4961-4969
Copyright: © Lien et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The present study aimed to identify a feasible treatment strategy for hypopharyngeal cancer (HPC) with non‑extensive invasion of the thyroid and/or cricoid cartilage. Between June 2008 and December 2014, patients with previously untreated HPC invading cartilage who had received either open partial laryngectomy (OPL) with tube‑free tracheostomy or total laryngectomy (TL) with permanent tracheostomy and an artificial larynx (pneumatic tube) were retrospectively reviewed. The patients with extensive cartilage invasion and those with inoperable or T4b disease were excluded for OPL. Outcomes and quality of life were compared between the two treatment modalities. A total of 44 patients were included. The survival rates, complications, and Dysphagia Score were compared between the two treatment modalities. The outcome of the Voice Handicap Index (P=0.032), understandability of speech (P<0.001), normalcy of diet (P=0.041), senses (P=0.006), speech (P<0.001) and social contact (P=0.004) were significantly improved in the group receiving OPL compared with the group receiving TL. Therefore, OPL with tube‑free tracheostomy may be a feasible option to treat patients with HPC with non‑extensive invasion of the thyroid and/or cricoid cartilage.

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