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Characteristics and predictors of malignancy in dermatomyositis: Analysis of 239 patients from northern China

  • Authors:
    • Ying Liu
    • Lulu Xu
    • Hongliang Wu
    • Na Zhao
    • Yanchun Tang
    • Xiaoping Li
    • Ying Liang
  • View Affiliations / Copyright

    Affiliations: Department of Rheumatology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong 264000, P.R. China, Department of Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong 264000, P.R. China, Department of Neurology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong 264000, P.R. China, Department of Pneumology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong 264000, P.R. China
    Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 5960-5968
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    Published online on: September 5, 2018
       https://doi.org/10.3892/ol.2018.9409
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Abstract

The present study aimed to determine the characteristics of patients with dermatomyositis (DM) in order to identify predictors of cancer in these patients. Data of 239 patients with DM, treated at Yuhuangding Hospital between 1997 and 2016, was retrospectively assessed. The patients' demographic, clinical, survival and laboratory data were analyzed. Of the 239 patients, 43 developed malignancies. In 30 (69.77%) patients, the malignancy was detected within 1 year before or after DM diagnosis. There were 15 (34.88%) fatalities. Lung cancer was the most common type of malignancy identified (n=6, 13.95%), and adenocarcinoma was the most common pathological type (n=6, 13.95%). Older age, absence of interstitial lung disease, and absence of arthralgia were demonstrated to be independent risk factors for malignancy. Myositis‑specific autoantibody expression, specifically anti‑TIF1γ positivity and/or anti‑MDA5 negativity, was associated with cancer in patients with DM. The survival rate was significantly lower in patients with malignancy than in patients without malignancy. Patients with DM had a high incidence of malignancy and a poor prognosis. Lung cancer and adenocarcinoma are common among patients with DM in northern China. Cancer screening should be conducted in all DM patients, particularly within 1 year of DM diagnosis. Older age is a risk factor for malignancy in DM patients, while interstitial lung disease and arthralgia are protective factors. Myositis‑specific autoantibody detection may be useful for cancer screening in patients with DM.
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View References

1 

Fardet L, Dupuy A, Gain M, Kettaneh A, Chérin P, Bachelez H, Dubertret L, Lebbe C, Morel P and Rybojad M: Factors associated with underlying malignancy in a retrospective cohort of 121 patients with dermatomyositis. Medicine (Baltimore). 88:91–97. 2009. View Article : Google Scholar : PubMed/NCBI

2 

Stertz G: Polymyositis. Berl Klin Wochenschr. 53:4891916.

3 

So MW, Koo BS, Kim YG, Lee CK and Yoo B: Idiopathic inflammatory myopathy associated with malignancy: A retrospective cohort of 151 Korean patients with dermatomyositis and polymyositis. J Rheumatol. 38:2432–2435. 2011. View Article : Google Scholar : PubMed/NCBI

4 

Lu X, Yang H, Shu X, Chen F, Zhang Y, Zhang S, Peng Q, Tian X and Wang G: Factors predicting malignancy in patients with polymyositis and dermatomyostis: A systematic review and meta-analysis. PLoS One. 9:e941282014. View Article : Google Scholar : PubMed/NCBI

5 

Fang YF, Wu YJ, Kuo CF, Luo SF and Yu KH: Malignancy in dermatomyositis and polymyositis: analysis of 192 patients. Clin Rheumatol. 35:1977–1984. 2016. View Article : Google Scholar : PubMed/NCBI

6 

Zampieri S, Valente M, Adami N, Biral D, Ghirardello A, Rampudda ME, Vecchiato M, Sarzo G, Corbianco S, Kern H, et al: Polymyositis, dermatomyositis and malignancy: A further intriguing link. Autoimmun Rev. 9:449–453. 2010. View Article : Google Scholar : PubMed/NCBI

7 

Zantos D, Zhang Y and Felson D: The overall and temporal association of cancer with polymyositis and dermatomyositis. J Rheumatol. 21:1855–1859. 1994.PubMed/NCBI

8 

Buchbinder R and Hill CL: Malignancy in patients with inflammatory myopathy. Curr Rheumatol Rep. 4:415–426. 2002. View Article : Google Scholar : PubMed/NCBI

9 

Madan V, Chinoy H, Griffiths CE and Cooper RG: Defining cancer risk in dermatomyositis. Part I. Clin Exp Dermatol. 34:451–455. 2009. View Article : Google Scholar : PubMed/NCBI

10 

Zahr ZA and Baer AN: Malignancy in myositis. Curr Rheumatol Rep. 13:208–215. 2011. View Article : Google Scholar : PubMed/NCBI

11 

Jouary T, Gracia C, Lalanne N, Vital A, Taieb A and Delaunay M: Rapidly lethal dermatomyositis associated with metastatic melanoma. J Eur Acad Dermatol Venereol. 22:399–401. 2008. View Article : Google Scholar : PubMed/NCBI

12 

Teoh JW, Yunus RM, Hassan F, Ghazali N and Abidin ZA: Nasopharyngeal carcinoma in dermatomyositis patients: A 10-year retrospective review in Hospital Selayang, Malaysia. Rep Pract Oncol Radiother. 19:332–336. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Noda T, Iijima M, Noda S, Maeshima S, Nakanishi H, Kimura S, Koike H, Ishigaki S, Iguchi Y, Katsuno M and Sobue G: Gene expression profile of inflammatory myopathy with malignancy is similar to that of dermatomyositis rather than polymyositis. Intern Med. 55:2571–2580. 2016. View Article : Google Scholar : PubMed/NCBI

14 

Hoshino K, Muro Y, Sugiura K, Tomita Y, Nakashima R and Mimori T: Anti-MDA5 and anti-TIF1-gamma antibodies have clinical significance for patients with dermatomyositis. Rheumatology (Oxford). 49:1726–1733. 2010. View Article : Google Scholar : PubMed/NCBI

15 

Bohan A and Peter JB: Polymyositis and dermatomyositis (second of two parts). N Engl J Med. 292:403–407. 1975. View Article : Google Scholar : PubMed/NCBI

16 

Ikeda S, Arita M, Misaki K, Mishima S, Takaiwa T, Nishiyama A, Ito A, Furuta K, Yokoyama T, Tokioka F, et al: Incidence and impact of interstitial lung disease and malignancy in patients with polymyositis, dermatomyositis, and clinically amyopathic dermatomyositis: A retrospective cohort study. SpringerPlus. 4:2402015. View Article : Google Scholar : PubMed/NCBI

17 

Stockton D, Doherty VR and Brewster DH: Risk of cancer in patients with dermatomyositis or polymyositis, and follow-up implications: A Scottish population-based cohort study. Br J Cancer. 85:41–45. 2001. View Article : Google Scholar : PubMed/NCBI

18 

Leatham H, Schadt C, Chisolm S, Fretwell D, Chung L, Callen JP and Fiorentino D: Evidence supports blind screening for internal malignancy in dermatomyositis: Data from 2 large US dermatology cohorts. Medicine (Baltimore). 97:e96392018. View Article : Google Scholar : PubMed/NCBI

19 

de Souza FH and Shinjo SK: Newly diagnosed dermatomyositis in the elderly as predictor of malignancy. Rev Bras Reumatol. 52:713–721. 2012.PubMed/NCBI

20 

Sigurgeirsson B, Lindelof B, Edhag O and Allander E: Risk of cancer in patients with dermatomyositis or polymyositis. A population-based study. N Engl J Med. 326:363–367. 1992. View Article : Google Scholar : PubMed/NCBI

21 

Ungprasert P, Leeaphorn N, Hosiriluck N, Chaiwatcharayut W, Ammannagari N and Raddatz DA: Clinical features of inflammatory myopathies and their association with malignancy: A systematic review in Asian population. ISRN Rheumatology. 2013:5093542013. View Article : Google Scholar : PubMed/NCBI

22 

Chen D, Yuan S, Wu X, Li H, Qiu Q, Zhan Z, Ye Y, Lian F, Liang L, Xu H and Yang X: Incidence and predictive factors for malignancies with dermatomyositis: A cohort from southern China Clin Exp Rheumatol. 32:615–621. 2014.

23 

Zhang W, Jiang SP and Huang L: Dermatomyositis and malignancy: A retrospective study of 115 cases. Eur Rev Med Pharmacol Sci. 13:77–80. 2009.PubMed/NCBI

24 

Wei KR, Zheng RS, Zhang SW, Liang ZH, Ou ZX and Chen WQ: Nasopharyngeal carcinoma incidence and mortality in China in 2010. Chin J Cancer. 33:381–387. 2014.PubMed/NCBI

25 

Hill CL, Zhang Y, Sigurgeirsson B, Pukkala E, Mellemkjaer L, Airio A, Evans SR and Felson DT: Frequency of specific cancer types in dermatomyositis and polymyositis: A population-based study. Lancet. 357:96–100. 2001. View Article : Google Scholar : PubMed/NCBI

26 

Mebazaa A, Boussen H, Nouira R, Rokbani L, Ben Osman-Dhahri A, Bouaouina N, Laouani-Kechrid C, Louzir B, Zahaf A and Kamoun MR: Dermatomyositis and malignancy in Tunisia: A multicenter national retrospective study of 20 cases. J Am Acad Dermatol. 48:530–534. 2003. View Article : Google Scholar : PubMed/NCBI

27 

Travassos AR, Borges-Costa J, Filipe P and Marques MS: Malignancy associated with dermatomyositis-A retrospective single-center study with 33 patients. Acta Reumatol Port. 38:92–97. 2013.PubMed/NCBI

28 

Azuma K, Yamada H, Ohkubo M, Yamasaki Y, Yamasaki M, Mizushima M and Ozaki S: Incidence and predictive factors for malignancies in 136 Japanese patients with dermatomyositis, polymyositis and clinically amyopathic dermatomyositis. Mod Rheumatol. 21:178–183. 2011. View Article : Google Scholar : PubMed/NCBI

29 

Fung WK, Chan HL and Lam WM: Amyopathic dermatomyositis in Hong Kong-Association with nasopharyngeal carcinoma. Int J Dermatol. 37:659–663. 1998. View Article : Google Scholar : PubMed/NCBI

30 

Yosipovitch G, Tan A, LoSicco K, Manabat CG, Kannagra A, Carroll C, Chan YH, Ng P and Jorizzo J: A comparative study of clinical characteristics, work-up, treatment, and association to malignancy in dermatomyositis between two tertiary skin centers in the USA and Singapore. Int J Dermatol. 52:813–819. 2013. View Article : Google Scholar : PubMed/NCBI

31 

Andras C, Ponyi A, Constantin T, Csiki Z, Szekanecz E, Szodoray P and Dankó K: Dermatomyositis and polymyositis associated with malignancy: A 21-year retrospective study. J Rheumatol. 35:438–444. 2008.PubMed/NCBI

32 

Wakata N, Kurihara T, Saito E and Kinoshita M: Polymyositis and dermatomyositis associated with malignancy: A 30-year retrospective study. Int J Dermatol. 41:729–734. 2002. View Article : Google Scholar : PubMed/NCBI

33 

Qiang JK, Kim WB, Baibergenova A and Alhusayen R: Risk of malignancy in dermatomyositis and polymyositis: A systematic review and meta-analysis. J Cutan Med Surg. 21:131–136. 2017. View Article : Google Scholar : PubMed/NCBI

34 

Masuda H, Urushibara M and Kihara K: Successful treatment of dermatomyositis associated with adenocarcinoma of the prostate after radical prostatectomy. J Urol. 169:10842003. View Article : Google Scholar : PubMed/NCBI

35 

Yoshinaga A, Hayashi T, Ishii N, Ohno R, Watanabe T and Yamada T: Successful cure of dermatomyositis after treatment of nonseminomatous testicular cancer. Int J Urol. 12:593–595. 2005. View Article : Google Scholar : PubMed/NCBI

36 

Mahe E, Descamps V, Burnouf M and Crickx B: A helpful clinical sign predictive of cancer in adult dermatomyositis: Cutaneous necrosis. Arch Dermatol. 139:5392003.PubMed/NCBI

37 

Giovannucci E, Harlan DM, Archer MC, Archer MC, Bergenstal RM, Gapstur SM, Habel LA, Pollak M, Regensteiner JG and Yee D: Diabetes and cancer: A consensus report. Diabetes Care. 33:1674–1685. 2010. View Article : Google Scholar : PubMed/NCBI

38 

Vigneri P, Frasca F, Sciacca L, Pandini G and Vigneri R: Diabetes and cancer. Endocr Relat Cancer. 16:1103–1123. 2009. View Article : Google Scholar : PubMed/NCBI

39 

Lukanova A, Zeleniuch-Jacquotte A, Lundin E, Micheli A, Arslan AA, Rinaldi S, Muti P, Lenner P, Koenig KL, Biessy C, et al: Prediagnostic levels of C-peptide, IGF-I, IGFBP −1, −2 and −3 and risk of endometrial cancer. Int J Cancer. 108:262–268. 2004. View Article : Google Scholar : PubMed/NCBI

40 

Yang J, Nishihara R, Zhang X, Ogino S and Qian ZR: Energy sensing pathways: Bridging type 2 diabetes and colorectal cancer? J Diabetes Complications. 31:1228–1236. 2017. View Article : Google Scholar : PubMed/NCBI

41 

Betteridge ZE, Gunawardena H and McHugh NJ: Novel autoantibodies and clinical phenotypes in adult and juvenile myositis. Arthritis Res Ther. 13:2092011. View Article : Google Scholar : PubMed/NCBI

42 

Casciola-Rosen L and Mammen AL: Myositis autoantibodies. Curr Opin Rheumatol. 24:602–608. 2012. View Article : Google Scholar : PubMed/NCBI

43 

Targoff IN, Mamyrova G, Trieu EP, Perurena O, Koneru B, O'Hanlon TP, Miller FW and Rider LG; and Childhood Myositis Heterogeneity Study Group, : International Myositis Collaborative Study Group: A novel autoantibody to a 155-kd protein is associated with dermatomyositis. Arthritis Rheum. 54:3682–3689. 2006. View Article : Google Scholar : PubMed/NCBI

44 

Kaji K, Fujimoto M, Hasegawa M, Kondo M, Saito Y, Komura K, Matsushita T, Orito H, Hamaguchi Y, Yanaba K, et al: Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: An association with malignancy. Rheumatology (Oxford). 46:25–28. 2007. View Article : Google Scholar : PubMed/NCBI

45 

Chinoy H, Fertig N, Oddis CV, Ollier WE and Cooper RG: The diagnostic utility of myositis autoantibody testing for predicting the risk of cancer-associated myositis. Ann Rheum Dis. 66:1345–1349. 2007. View Article : Google Scholar : PubMed/NCBI

46 

Gunawardena H, Wedderburn LR, North J, Betteridge Z, Dunphy J, Chinoy H, Davidson JE, Cooper RG and McHugh NJ; and Juvenile Dermatomyositis Research Group UK, : Clinical associations of autoantibodies to a p155/140 kDa doublet protein in juvenile dermatomyositis. Rheumatology (Oxford). 47:324–328. 2008. View Article : Google Scholar : PubMed/NCBI

47 

Ceribelli A, Isailovic N, De Santis M, Generali E, Fredi M, Cavazzana I, Franceschini F, Cantarini L, Satoh M and Selmi C: Myositis-specific autoantibodies and their association with malignancy in Italian patients with polymyositis and dermatomyositis. Clin Rheumatol. 36:469–475. 2017. View Article : Google Scholar : PubMed/NCBI

48 

Trallero-Araguas E, Rodrigo-Pendas JA, Selva-O'Callaghan A, Martínez-Gómez X, Bosch X, Labrador-Horrillo M, Grau-Junyent JM and Vilardell-Tarrés M: Usefulness of anti-p155 autoantibody for diagnosing cancer-associated dermatomyositis: A systematic review and meta-analysis. Arthritis Rheum. 64:523–532. 2012. View Article : Google Scholar : PubMed/NCBI

49 

Dupont S, Zacchigna L, Cordenonsi M, Soligo S, Adorno M, Rugge M and Piccolo S: Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase. Cell. 121:87–99. 2005. View Article : Google Scholar : PubMed/NCBI

50 

Sato S, Hirakata M, Kuwana M, Suwa A, Inada S, Mimori T, Nishikawa T, Oddis CV and Ikeda Y: Autoantibodies to a 140-kd polypeptide, CADM-140, in Japanese patients with clinically amyopathic dermatomyositis. Arthritis Rheum. 52:1571–1576. 2005. View Article : Google Scholar : PubMed/NCBI

51 

Ichimura Y, Matsushita T, Hamaguchi Y, Kaji K, Hasegawa M, Tanino Y, Inokoshi Y, Kawai K, Kanekura T, Habuchi M, et al: Anti-NXP2 autoantibodies in adult patients with idiopathic inflammatory myopathies: Possible association with malignancy. Ann Rheum Dis. 71:710–713. 2012. View Article : Google Scholar : PubMed/NCBI

52 

Fiorentino DF, Chung LS, Christopher-Stine L, Zaba L, Li S, Mammen AL, Rosen A and Casciola-Rosen L: Most patients with cancer-associated dermatomyositis have antibodies to nuclear matrix protein NXP-2 or transcription intermediary factor 1gamma. Arthritis Rheum. 65:2954–2962. 2013. View Article : Google Scholar : PubMed/NCBI

53 

Albayda J, Pinal-Fernandez I, Huang W, Parks C, Paik J, Casciola-Rosen L, Danoff SK, Johnson C, Christopher-Stine L and Mammen AL: Antinuclear matrix protein 2 autoantibodies and edema, muscle disease, and malignancy risk in dermatomyositis patients. Arthritis Care Res. (Hoboken). 69:1771–1776. 2017.

54 

Airio A, Kautiainen H and Hakala M: Prognosis and mortality of polymyositis and dermatomyositis patients. Clin Rheumatol. 25:234–239. 2006. View Article : Google Scholar : PubMed/NCBI

55 

Danko K, Ponyi A, Constantin T, Borgulya G and Szegedi G: Long-term survival of patients with idiopathic inflammatory myopathies according to clinical features: A longitudinal study of 162 cases. Medicine (Baltimore). 83:35–42. 2004. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Liu Y, Xu L, Wu H, Zhao N, Tang Y, Li X and Liang Y: Characteristics and predictors of malignancy in dermatomyositis: Analysis of 239 patients from northern China. Oncol Lett 16: 5960-5968, 2018.
APA
Liu, Y., Xu, L., Wu, H., Zhao, N., Tang, Y., Li, X., & Liang, Y. (2018). Characteristics and predictors of malignancy in dermatomyositis: Analysis of 239 patients from northern China. Oncology Letters, 16, 5960-5968. https://doi.org/10.3892/ol.2018.9409
MLA
Liu, Y., Xu, L., Wu, H., Zhao, N., Tang, Y., Li, X., Liang, Y."Characteristics and predictors of malignancy in dermatomyositis: Analysis of 239 patients from northern China". Oncology Letters 16.5 (2018): 5960-5968.
Chicago
Liu, Y., Xu, L., Wu, H., Zhao, N., Tang, Y., Li, X., Liang, Y."Characteristics and predictors of malignancy in dermatomyositis: Analysis of 239 patients from northern China". Oncology Letters 16, no. 5 (2018): 5960-5968. https://doi.org/10.3892/ol.2018.9409
Copy and paste a formatted citation
x
Spandidos Publications style
Liu Y, Xu L, Wu H, Zhao N, Tang Y, Li X and Liang Y: Characteristics and predictors of malignancy in dermatomyositis: Analysis of 239 patients from northern China. Oncol Lett 16: 5960-5968, 2018.
APA
Liu, Y., Xu, L., Wu, H., Zhao, N., Tang, Y., Li, X., & Liang, Y. (2018). Characteristics and predictors of malignancy in dermatomyositis: Analysis of 239 patients from northern China. Oncology Letters, 16, 5960-5968. https://doi.org/10.3892/ol.2018.9409
MLA
Liu, Y., Xu, L., Wu, H., Zhao, N., Tang, Y., Li, X., Liang, Y."Characteristics and predictors of malignancy in dermatomyositis: Analysis of 239 patients from northern China". Oncology Letters 16.5 (2018): 5960-5968.
Chicago
Liu, Y., Xu, L., Wu, H., Zhao, N., Tang, Y., Li, X., Liang, Y."Characteristics and predictors of malignancy in dermatomyositis: Analysis of 239 patients from northern China". Oncology Letters 16, no. 5 (2018): 5960-5968. https://doi.org/10.3892/ol.2018.9409
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