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Case Report Open Access

Analyses and treatment of simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma: Two case reports and a literature review

  • Authors:
    • Xiaorui Fu
    • Yufeng Shang
    • Lei Zhang
    • Ling Li
    • Xin Li
    • Xinhua Wang
    • Zhenchang Sun
    • Mingzhi Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450002, P.R. China
    Copyright: © Fu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 6624-6632
    |
    Published online on: September 18, 2018
       https://doi.org/10.3892/ol.2018.9447
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Abstract

The present study reports two cases of concurrently diagnosed T‑lymphoblastic lymphoma (T‑LBL) and chronic myeloid leukemia (CML). The literature review revealed that myeloid leukemia may appear secondary to Hodgkin lymphoma or non‑Hodgkin lymphoma. However, simultaneous bi‑lineage hematologic malignancies are rarely seen and the prognosis is worse than single lineage lymphoma or myeloid leukemia. There were no standard therapies. All simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma reported in Pubmed were combined with the present two cases, to analyses its pathogenesis, features and treatment. It was concluded that the prognosis of bi‑lineage hematologic malignancies was poor, however allogeneic hematopoietic stem cell transplantation could improve survival (P=0.033).
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Copy and paste a formatted citation
Spandidos Publications style
Fu X, Shang Y, Zhang L, Li L, Li X, Wang X, Sun Z and Zhang M: Analyses and treatment of simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma: Two case reports and a literature review. Oncol Lett 16: 6624-6632, 2018.
APA
Fu, X., Shang, Y., Zhang, L., Li, L., Li, X., Wang, X. ... Zhang, M. (2018). Analyses and treatment of simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma: Two case reports and a literature review. Oncology Letters, 16, 6624-6632. https://doi.org/10.3892/ol.2018.9447
MLA
Fu, X., Shang, Y., Zhang, L., Li, L., Li, X., Wang, X., Sun, Z., Zhang, M."Analyses and treatment of simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma: Two case reports and a literature review". Oncology Letters 16.5 (2018): 6624-6632.
Chicago
Fu, X., Shang, Y., Zhang, L., Li, L., Li, X., Wang, X., Sun, Z., Zhang, M."Analyses and treatment of simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma: Two case reports and a literature review". Oncology Letters 16, no. 5 (2018): 6624-6632. https://doi.org/10.3892/ol.2018.9447
Copy and paste a formatted citation
x
Spandidos Publications style
Fu X, Shang Y, Zhang L, Li L, Li X, Wang X, Sun Z and Zhang M: Analyses and treatment of simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma: Two case reports and a literature review. Oncol Lett 16: 6624-6632, 2018.
APA
Fu, X., Shang, Y., Zhang, L., Li, L., Li, X., Wang, X. ... Zhang, M. (2018). Analyses and treatment of simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma: Two case reports and a literature review. Oncology Letters, 16, 6624-6632. https://doi.org/10.3892/ol.2018.9447
MLA
Fu, X., Shang, Y., Zhang, L., Li, L., Li, X., Wang, X., Sun, Z., Zhang, M."Analyses and treatment of simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma: Two case reports and a literature review". Oncology Letters 16.5 (2018): 6624-6632.
Chicago
Fu, X., Shang, Y., Zhang, L., Li, L., Li, X., Wang, X., Sun, Z., Zhang, M."Analyses and treatment of simultaneous bi‑lineage malignancies of myeloid leukemia and lymphoma: Two case reports and a literature review". Oncology Letters 16, no. 5 (2018): 6624-6632. https://doi.org/10.3892/ol.2018.9447
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