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Article

Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi

  • Authors:
    • Mengge Li
    • Yalin Zhao
    • Xiaoli Liu
    • Zhibo Dang
    • Xinhui Wang
    • Yuyong Jiang
    • Zhiyun Yang
  • View Affiliations / Copyright

    Affiliations: Department of Traditional Chinese Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, P.R. China, Digestive Department, The People's Hospital of Hebi, Hebi, Henan 458000, P.R. China
    Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 119-126
    |
    Published online on: October 17, 2018
       https://doi.org/10.3892/ol.2018.9590
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Abstract

The development of minimally invasive treatment over the last two decades has had a great impact on hepatitis B virus (HBV)‑associated primary liver cancer. The model for end‑stage liver disease (MELD) score is the optimal evaluated parameter for mortality in patients with end‑stage liver disease. However, the association between MELD score and minimally invasive treatment with regard to the mortality of patients with HBV‑associated hepatocellular carcinoma (HCC) with a portal vein tumor thrombus (PVTT) remains unclear. In the present study, a total of 173 patients who had been diagnosed with HBV‑associated HCC and PVTT in the Beijing Ditan Hospital (Beijing, China), between January 2012 and January 2015, were screened. Follow‑up was performed to observe the survival time and collect information on the demographic characteristics and associated clinical indicators present in the cohort. The patient's age, sex, laboratory parameters and the use of minimally invasive treatment were analyzed with SPSS 20.0 software. Independent risk factors for mortality were screened by Cox regression analysis. Logistic regression indicated that there was an interaction between the MELD score and minimally invasive treatment. In addition, a MELD score ≤17.85 was associated with a lower mortality rate subsequent to minimally invasive treatment.
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1 

Taketomi A: Clinical trials of antiangiogenic therapy for hepatocellular carcinoma. Int J Clin Oncol. 21:213–218. 2016. View Article : Google Scholar : PubMed/NCBI

2 

Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI

3 

Facciorusso A, Di Maso M and Muscatiello N: Drug-eluting beads versus conventional chemoembolization for the treatment of unresectable hepatocellular carcinoma: A meta-analysis. Dig Liver Dis. 48:571–577. 2016. View Article : Google Scholar : PubMed/NCBI

4 

Zhang ZM, Lai EC, Zhang C, Yu HW, Liu Z, Wan BJ, Liu LM, Tian ZH, Deng H, Sun QH and Chen XP: The strategies for treating primary hepatocellular carcinoma with portal vein tumor thrombus. Int J Surg. 20:8–16. 2015. View Article : Google Scholar : PubMed/NCBI

5 

Bucci L, Garuti F, Lenzi B, Pecorelli A, Farinati F, Giannini EG, Granito A, Ciccarese F, Rapaccini GL, Di Marco M, et al: The evolutionary scenario of hepatocellular carcinoma in Italy: An update. Liver Int. 37:259–270. 2017. View Article : Google Scholar : PubMed/NCBI

6 

Ramirez AG, Munoz E, Holden AE, Adeigbe RT and Suarez L: Incidence of hepatocellular carcinoma in Texas Latinos, 1995-2010: An update. PLoS One. 9:e993652014. View Article : Google Scholar : PubMed/NCBI

7 

Nakazawa T, Adachi S, Kitano M, Isobe Y, Kokubu S, Hidaka H, Ono K, Okuwaki Y, Watanabe M, Shibuya A, et al: Potential prognostic benefits of radiotherapy as an initial treatment for patients with unresectable advanced hepatocellular carcinoma with invasion to intrahepatic large vessels. Oncology. 73:90–97. 2017. View Article : Google Scholar

8 

Tanaka Y, Nakazawa T, Komori S, Hidaka H, Okuwaki Y, Takada J, Watanabe M, Shibuya A, Minamino T, Yamamoto H, et al: Radiotherapy for patients with unresectable advanced hepatocellular carcinoma with invasion to intrahepatic large vessels: Efficacy and outcomes. J Gastroenterol Hepatol. 29:352–357. 2014. View Article : Google Scholar : PubMed/NCBI

9 

Stippel DL, Wahba R, Bruns CJ, Bunck A, Baues C and Persigehl T: Image-guided, minimally invasive surgery and other local therapeutic procedures for primary liver tumors. Chirug. 2018.(In German).

10 

Bruix J and Sherman M; American Association for the Study of Liver Diseases, . Management of hepatocellular carcinoma: An update. Hepatology. 53:1020–1022. 2011. View Article : Google Scholar : PubMed/NCBI

11 

Shen A, Tang C, Wang Y, Chen Y, Yan X, Zhang C, Liu R, Wei X, Zhu Y, Zhang H and Wu Z: A systematic review of sorafenib in Child-Pugh A patients with unresectable hepatocellular carcinoma. J Clin Gastroenterol. 47:871–880. 2013. View Article : Google Scholar : PubMed/NCBI

12 

Cheah YL and Chow PKH: Liver transplantation for hepatocellular carcinoma: An appraisal of current controversies. Liver Cancer. 1:183–189. 2012. View Article : Google Scholar : PubMed/NCBI

13 

Malinchoc M, Kamath PS, Gordon FD, Peine CJ, Rank J and ter Borg PC: A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts. Hepatology. 31:864–871. 2000. View Article : Google Scholar : PubMed/NCBI

14 

Eguchi S, Kanematsu T, Arii S, Omata M, Kudo M, Sakamoto M, Takayasu K, Makuuchi M, Matsuyama Y and Monden M; Liver Cancer Study Group of Japan, . Recurrence-free survival more than 10 years after liver resection for hepatocellular carcinoma. Br J Surg. 98:552–557. 2011. View Article : Google Scholar : PubMed/NCBI

15 

Zou Z, Yuan Z, Zhang Q, Long Z, Chen J, Tang Z, Zhu Y, Chen S, Xu J, Yan M, et al: Aurora kinase A inhibition-induced autophagy triggers drug resistance in breast cancer cells. Autophagy. 8:1798–1810. 2012. View Article : Google Scholar : PubMed/NCBI

16 

Gao J, Zou Z, Gao J, Zhang H, Lin Z, Zhang Y, Luo X, Liu C, Xie J and Cai C: Increased expression of HMGB3: A novel independent prognostic marker of worse outcome in patients with esophageal squamous cell carcinoma. Int J Clin Exp Pathol. 8:345–352. 2015.PubMed/NCBI

17 

Tandon P and Garcia-Tsao G: Prognostic indicators in hepatocellular carcinoma: A systematic review of 72 studies. Liver Int. 29:502–510. 2009. View Article : Google Scholar : PubMed/NCBI

18 

Zhang TT, Zhao XQ, Liu Z, Mao ZY and Bai L: Factors affecting the recurrence and survival of hepatocellular carcinoma after hepatectomy: A retrospective study of 601 Chinese patients. Clin Transl Oncol. 18:831–840. 2016. View Article : Google Scholar : PubMed/NCBI

19 

Schöniger-Hekele M, Müller C, Kutilek M, Oesterreicher C, Ferenci P and Gangl A: Hepatocellular carcinoma in Central Europe: Prognostic features and survival. Gut. 48:103–109. 2001. View Article : Google Scholar : PubMed/NCBI

20 

Llovet JM, Bustamante J, Castells A, Vilana R, Ayuso Mdel C, Sala M, Brú C, Rodés J and Bruix J: Natural history of untreated nonsurgical hepatocellular carcinoma: Rationale for the design and evaluation of therapeutic trials. Hepatology. 29:62–67. 1999. View Article : Google Scholar : PubMed/NCBI

21 

Kokudo T, Hasegawa K, Matsuyama Y, Takayama T, Izumi N, Kadoya M, Kudo M, Ku Y, Sakamoto M, Nakashima O, et al: Survival benefit of liver resection for hepatocellular carcinoma associated with portal vein invasion. J Hepatol. 65:938–943. 2016. View Article : Google Scholar : PubMed/NCBI

22 

Huang M, Lin Q, Wang H, Chen J, Bai M, Wang L, Zhu K, Jiang Z, Guan S, Li Z, et al: Survival benefit of chemoembolization plus Iodine125 seed implantation in unresectable hepatitis B-related hepatocellular carcinoma with PVTT: A retrospective matched cohort study. Eur Radiol. 26:3428–3436. 2016. View Article : Google Scholar : PubMed/NCBI

23 

Lu XJ, Dong J, Ji LJ, Luo JH, Cao HM, Xiao LX, Zhou J and Ling CQ: Safety and efficacy of TACE and gamma knife on hepatocellular carcinoma with portal vein invasion. Gut. 65:715–716. 2016. View Article : Google Scholar : PubMed/NCBI

24 

Riaz A, Ryu RK, Kulik LM, Mulcahy MF, Lewandowski RJ, Minocha J, Ibrahim SM, Sato KT, Baker T, Miller FH, et al: Alpha-fetoprotein response after locoregional therapy for hepatocellular carcinoma: Oncologic marker of radiologic response, progression, and survival. J Clin Oncol. 27:5734–5742. 2009. View Article : Google Scholar : PubMed/NCBI

25 

Chan SL, Mo FK, Johnson PJ, Hui EP, Ma BB, Ho WM, Lam KC, Chan AT, Mok TS and Yeo W: New utility of an old marker: Serial alpha-fetoprotein measurement in predicting radiologic response and survival of patients with hepatocellular carcinoma undergoing systemic chemotherapy. J Clin Oncol. 27:446–452. 2009. View Article : Google Scholar : PubMed/NCBI

26 

Lee MH, Kim SU, Kim DY, Ahn SH, Choi EH, Lee KH, Lee DY, Seong J, Han KH, Chon CY and Park JY: Early on-treatment predictions of clinical outcomes using alpha-fetoprotein and des-gamma-carboxy prothrombin responses in patients with advanced hepatocellular carcinoma. J Gastroenterol Hepatol. 27:313–322. 2012. View Article : Google Scholar : PubMed/NCBI

27 

Nobuoka D, Kato Y, Gotohda N, Takahashi S, Nakagohri T, Konishi M, Kinoshita T and Nakatsura T: Postoperative serum alpha-fetoprotein level is a useful predictor of recurrence after hepatectomy for hepatocellular carcinoma. Oncol Rep. 24:521–528. 2010.PubMed/NCBI

28 

Bujold A, Massey CA, Kim JJ, Brierley J, Cho C, Wong RK, Dinniwell RE, Kassam Z, Ringash J, Cummings B, et al: Sequential phase I and II trials of stereotactic body radiotherapy for locally advanced hepatocellular carcinoma. J Clin Oncol. 31:1631–1639. 2013. View Article : Google Scholar : PubMed/NCBI

29 

Kubo S, Hirohashi K, Tanaka H, Tsukamoto T, Shuto T, Yamamoto T, Ikebe T, Wakasa K, Nishiguchi S and Kinoshita H: Effect of viral status on recurrence after liver resection for patients with hepatitis B virus-related hepatocellular carcinoma. Cancer-Am Cancer Soc. 88:1016–1024. 2000.

30 

Ohkubo K, Kato Y, Ichikawa T, Kajiya Y, Takeda Y, Higashi S, Hamasaki K, Nakao K, Nakata K and Eguchi K: Viral load is a significant prognostic factor for hepatitis B virus-associated hepatocellular carcinoma. Cancer. 94:2663–2668. 2002. View Article : Google Scholar : PubMed/NCBI

31 

Hirooka M, Koizumi Y, Kisaka Y, Abe M, Murakami H, Matsuura B, Hiasa Y and Onji M: Mass reduction by radiofrequency ablation before hepatic arterial infusion chemotherapy improved prognosis for patients with huge hepatocellular carcinoma and portal vein thrombus. AJR Am J Roentgenol. 194:W221–W226. 2010. View Article : Google Scholar : PubMed/NCBI

32 

Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP and Feng S: Development of a novel frailty index to predict mortality in patients with end-stage liver disease. Hepatology. 66:564–574. 2017. View Article : Google Scholar : PubMed/NCBI

33 

Benko T, Gallinat A, Minor T, Saner FH, Sotiropoulos GC, Paul A and Hoyer DP: The postoperative model for end stage liver disease score as a predictor of short-term outcome after transplantation of extended criteria donor livers. Eur J Gastroenterol Hepatol. 29:716–722. 2017. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Li M, Zhao Y, Liu X, Dang Z, Wang X, Jiang Y and Yang Z: Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi. Oncol Lett 17: 119-126, 2019.
APA
Li, M., Zhao, Y., Liu, X., Dang, Z., Wang, X., Jiang, Y., & Yang, Z. (2019). Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi. Oncology Letters, 17, 119-126. https://doi.org/10.3892/ol.2018.9590
MLA
Li, M., Zhao, Y., Liu, X., Dang, Z., Wang, X., Jiang, Y., Yang, Z."Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi". Oncology Letters 17.1 (2019): 119-126.
Chicago
Li, M., Zhao, Y., Liu, X., Dang, Z., Wang, X., Jiang, Y., Yang, Z."Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi". Oncology Letters 17, no. 1 (2019): 119-126. https://doi.org/10.3892/ol.2018.9590
Copy and paste a formatted citation
x
Spandidos Publications style
Li M, Zhao Y, Liu X, Dang Z, Wang X, Jiang Y and Yang Z: Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi. Oncol Lett 17: 119-126, 2019.
APA
Li, M., Zhao, Y., Liu, X., Dang, Z., Wang, X., Jiang, Y., & Yang, Z. (2019). Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi. Oncology Letters, 17, 119-126. https://doi.org/10.3892/ol.2018.9590
MLA
Li, M., Zhao, Y., Liu, X., Dang, Z., Wang, X., Jiang, Y., Yang, Z."Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi". Oncology Letters 17.1 (2019): 119-126.
Chicago
Li, M., Zhao, Y., Liu, X., Dang, Z., Wang, X., Jiang, Y., Yang, Z."Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi". Oncology Letters 17, no. 1 (2019): 119-126. https://doi.org/10.3892/ol.2018.9590
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