Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
April-2019 Volume 17 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
April-2019 Volume 17 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Measurement of morphological parameters of giant cell tumor of bone in the knee

  • Authors:
    • Lin Guo
    • Peng Jia
    • Yong‑Cheng Hu
    • Man Sun
    • Zhi Wang
    • Xue‑Ning Zhang
    • Jun Miao
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Tianjin Hospital, Tianjin 300211, P.R. China, Department of Orthopaedics, Tianjin Hospital, Tianjin 300211, P.R. China, Department of Bone Tumors, Tianjin Hospital, Tianjin 300211, P.R. China, Department of Radiology, The Second Hospital of Tianjin Medical University, Tianjin 300211, P.R. China
    Copyright: © Guo et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3867-3873
    |
    Published online on: February 21, 2019
       https://doi.org/10.3892/ol.2019.10064
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The aim of the present study was to characterize the morphological parameters of giant cell tumor of bone (GCTB) in the knee. The imaging data of 250 patients with GCTB in the knee were retrospectively reviewed, and the morphological parameters were analyzed. The study included 137 cases with GCTB in the distal femur and 113 cases with GCTB in the proximal tibia. The maximal longitudinal diameter of the tumor was 6.616±2.322 cm in the femur group and 5.738±2.278 cm in the tibia group (P=0.003). The maximal transverse diameter in the two groups was 4.865±1.525 and 4.313±1.309 cm, respectively (P=0.003). The shortest distance from the articular surface (SDAS) in the two groups was 0.381±0.404 and 0.280±0.328 cm, respectively (P=0.035), whereas the longest distance from the articular surface in the two groups was 6.924±2.135 and 5.878±1.825 cm, respectively (P=0.001). There were statistically significant differences between the two groups in terms of the range of SDAS (P=0.043). Additionally, the incidence of pathological fractures in the femur was higher compared with that in the tibia (P=0.001), and the incidence of pathological fractures in the two groups gradually increased with the increase in lesion diameter. GCTB in the distal femur was larger compared with that in the proximal tibia, whereas GCTB in the tibia was closer to the articular surface compared with that in the femur. Furthermore, the incidence of pathological fractures in the femur was higher compared with that in the tibia.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Traub F, Singh J, Dickson BC, Leung S, Mohankumar R, Blackstein ME, Razak AR, Griffin AM, Ferguson PC and Wunder JS: Efficacy of denosumab in joint preservation for patients with giant cell tumour of the bone. Eur J Cancer. 59:1–12. 2016. View Article : Google Scholar : PubMed/NCBI

2 

Chan CM, Adler Z, Reith JD and Gibbs CP Jr: Risk factors for pulmonary metastases from giant cell tumor of bone. J Bone Joint Surg Am. 97:420–428. 2015. View Article : Google Scholar : PubMed/NCBI

3 

Sobti A, Agrawal P, Agarwala S and Agarwal M: Giant cell tumor of bone-an overview. Arch Bone Jt Surg. 4:2–9. 2016.PubMed/NCBI

4 

Fraquet N, Faizon G, Rosset P, Phillipeau JM, Waast D and Gouin F: Long bones giant cells tumors: Treatment by curretage and cavity filling cementation. Orthop Traumatol Surg Res. 95:402–406. 2009. View Article : Google Scholar : PubMed/NCBI

5 

Klenke FM, Wenger DE, Inwards CY, Rose PS and Sim FH: Giant cell tumor of bone: Risk factors for recurrence. Clin Orthop Relat Res. 469:591–599. 2011. View Article : Google Scholar : PubMed/NCBI

6 

Zhang S, Zhang J and Wang X: Comparison of tumor curettage and resection for treatment of giant cell tumor of the bone around the knee joint. Pak J Med Sci. 32:662–666. 2016. View Article : Google Scholar : PubMed/NCBI

7 

Balke M, Schremper L, Gebert C, Ahrens H, Streitbuerger A, Koehler G, Hardes J and Gosheger G: Giant cell tumor of bone: Treatment and outcome of 214 cases. J Cancer Res Clin Oncol. 134:969–978. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Boons HW, Keijser LC, Schreuder HW, Pruszczynski M, Lemmens JA and Veth RP: Oncologic and functional results after treatment of giant cell tumors of bone. Arch Orthop Trauma Surg. 122:17–23. 2002. View Article : Google Scholar : PubMed/NCBI

9 

Shin KH, Park HJ, Yoo JH and Hahn SB: Reconstructive surgery in primary malignant and aggressive benign bone tumor of the proximal humerus. Yonsei Med J. 41:304–311. 2000. View Article : Google Scholar : PubMed/NCBI

10 

Dürr HR, Maier M, Jansson V, Baur A and Refior HJ: Phenol as an adjuvant for local control in the treatment of giant cell tumour of the bone. Eur J Surg Oncol. 25:610–618. 1999. View Article : Google Scholar : PubMed/NCBI

11 

Deheshi BM, Jaffer SN, Griffin AM, Ferguson PC, Bell RS and Wunder JS: Joint salvage for pathologic fracture of giant cell tumor of the lower extremity. Clin Orthop Relat Res. 459:96–104. 2007. View Article : Google Scholar : PubMed/NCBI

12 

van der Heijden L, Dijkstra PD, Campanacci DA, Gibbons CL and van de Sande MA: Giant cell tumor with pathologic fracture: Should we curette or resect? Clin Orthop Relat Res. 471:820–829. 2013. View Article : Google Scholar

13 

Kivioja AH, Blomqvist C, Hietaniemi K, Trovik C, Walloe A, Bauer HC, Jorgensen PH, Bergh P and Follerås G: Cement is recommended in intralesional surgery of giant cell tumors: A scandinavian sarcoma group study of 294 patients followed for a median time of 5 years. Acta Orthop. 79:86–93. 2008. View Article : Google Scholar : PubMed/NCBI

14 

Hu YC: Related prognostic factors in surgical treatment of giant cell tumor of the knee around the knee. Chin J Orthop. 32:1083–1090. 2012.(In Chinese).

15 

Szendröi M: Giant-cell tumour of bone. J Bone Joint Surg Br. 86:5–12. 2004. View Article : Google Scholar : PubMed/NCBI

16 

Ward WG Sr and Li G III: Customized treatment algorithm for giant cell tumor of bone: Report of a series. Clin Orthop Relat Res. 259–270. 2002. View Article : Google Scholar : PubMed/NCBI

17 

Blackley HR, Wunder JS, Davis AM, White LM, Kandel R and Bell RS: Treatment of giant-cell tumors of long bones with curettage and bone-grafting. J Bone Joint Surg Am. 81:811–820. 1999. View Article : Google Scholar : PubMed/NCBI

18 

Dreinhöfer KE, Rydholm A, Bauer HC and Kreicbergs A: Giant-cell tumours with fracture at diagnosis. Curettage and acrylic cementing in ten cases. J Bone Joint Surg Br. 77:189–193. 1995. View Article : Google Scholar : PubMed/NCBI

19 

Jeys LM, Suneja R, Chami G, Grimer RJ, Carter SR and Tillman RM: Impending fractures in giant cell tumours of the distal femur: Incidence and outcome. Int Orthop. 30:135–138. 2006. View Article : Google Scholar : PubMed/NCBI

20 

Chen GJ, Wang Z, Wang L, Hu YC, Yu XC, Ye ZM, Wu SJ, Zhang GC and Guo SB: A multicenter retrospective study of artificial joint replacement on giant cell tumor in distal femur. Chin J Orthop. 38:338–345. 2018.

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Guo L, Jia P, Hu YC, Sun M, Wang Z, Zhang XN and Miao J: Measurement of morphological parameters of giant cell tumor of bone in the knee. Oncol Lett 17: 3867-3873, 2019.
APA
Guo, L., Jia, P., Hu, Y., Sun, M., Wang, Z., Zhang, X., & Miao, J. (2019). Measurement of morphological parameters of giant cell tumor of bone in the knee. Oncology Letters, 17, 3867-3873. https://doi.org/10.3892/ol.2019.10064
MLA
Guo, L., Jia, P., Hu, Y., Sun, M., Wang, Z., Zhang, X., Miao, J."Measurement of morphological parameters of giant cell tumor of bone in the knee". Oncology Letters 17.4 (2019): 3867-3873.
Chicago
Guo, L., Jia, P., Hu, Y., Sun, M., Wang, Z., Zhang, X., Miao, J."Measurement of morphological parameters of giant cell tumor of bone in the knee". Oncology Letters 17, no. 4 (2019): 3867-3873. https://doi.org/10.3892/ol.2019.10064
Copy and paste a formatted citation
x
Spandidos Publications style
Guo L, Jia P, Hu YC, Sun M, Wang Z, Zhang XN and Miao J: Measurement of morphological parameters of giant cell tumor of bone in the knee. Oncol Lett 17: 3867-3873, 2019.
APA
Guo, L., Jia, P., Hu, Y., Sun, M., Wang, Z., Zhang, X., & Miao, J. (2019). Measurement of morphological parameters of giant cell tumor of bone in the knee. Oncology Letters, 17, 3867-3873. https://doi.org/10.3892/ol.2019.10064
MLA
Guo, L., Jia, P., Hu, Y., Sun, M., Wang, Z., Zhang, X., Miao, J."Measurement of morphological parameters of giant cell tumor of bone in the knee". Oncology Letters 17.4 (2019): 3867-3873.
Chicago
Guo, L., Jia, P., Hu, Y., Sun, M., Wang, Z., Zhang, X., Miao, J."Measurement of morphological parameters of giant cell tumor of bone in the knee". Oncology Letters 17, no. 4 (2019): 3867-3873. https://doi.org/10.3892/ol.2019.10064
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team