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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2019 Volume 17 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

F‑box/WD‑40 repeat‑containing protein 7: A potential target in the progression and treatment of gastrointestinal malignancy (Review)

Yizhi Wang, Yang An, Yi Ma, Junchao Guo
Pages: 3625-3634
Published online on: 13 February 2019

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Review

A research update on the anticancer effects of bufalin and its derivatives (Review)

Yu‑Long Lan, Jia‑Cheng Lou, Xue‑Wen Jiang, Xun Wang, Jin‑Shan Xing, Shao Li, Bo Zhang
Pages: 3635-3640
Published online on: 21 February 2019

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Article Open Access

4‑Dimensional computed tomography analysis of clinical target volume displacement in adjuvant radiation of patients with gastric cancer and its implication on radiotherapy

Jin Peng, Jun Gong, Xiaoyong Wang, Jingjing Mou, Hui Xu, Jing Dai, Fuxiang Zhou, Yunfeng Zhou
Pages: 3641-3648
Published online on: 13 February 2019

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Article Open Access

Stratification of patients with colorectal cancer without the recorded family history

Ivana Kašubová, Michal Kalman, Karin Jašek, Tatiana Burjanivová, Bibiana Malicherová, Andrea Vaňochová, Sandra Meršaková, Zora Lasabová, Lukáš Plank
Pages: 3649-3656
Published online on: 06 February 2019

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Article Open Access

The oncogenic role of Wnt10a in colorectal cancer through activation of canonical Wnt/β‑catenin signaling

Jinlong Li, Zhaoli Zhang, Lixue Wang, Yongchen Zhang
Pages: 3657-3664
Published online on: 13 February 2019

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Article Open Access

Curative effect of endostar combined with oxaliplatin in the treatment of primary hepatic carcinoma and its influence on immune cells

Changjiang Lei, Defa Ren, Meixia Fu, Chuantao Sun, Hong Ren, Qingyun Pan, Yuan Li
Pages: 3665-3670
Published online on: 06 February 2019

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Article Open Access

Self‑made thoracic needled suspending device with a snare: An excellent aid for uniportal video‑assisted thoracic lobectomy and segmentectomy for lung cancer Corrigendum in /10.3892/ol.2020.11409

Shanlei Wang, Chuizheng Meng, Zhongmin Jiang, Diego Gonzalez-Rivas, Junfen Ruan, Wei Xu, Chuanping Liu, Lei Zhang, Guogang Gao, Ge Yu, Hezhi Teng, Jin Ju
Pages: 3671-3676
Published online on: 12 February 2019

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Article Open Access

In silico detection of potential prognostic circRNAs through a re‑annotation strategy in ovarian cancer

Qiuyan Guo, Yanan He, Liyuan Sun, Congcong Kong, Yan Cheng, Guangmei Zhang
Pages: 3677-3686
Published online on: 06 February 2019

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Article Open Access

Expression and prognostic significance of Fanconi anemia group D2 protein and breast cancer type 1 susceptibility protein in familial and sporadic breast cancer

Liang Feng, Feng Jin
Pages: 3687-3700
Published online on: 18 February 2019

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Article Open Access

Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines

Yu Li, Xin Chen, Yong Cui, Qun Wei, Suiyun Chen, Xiaofang Wang
Pages: 3701-3708
Published online on: 21 February 2019

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Article Open Access

P21 activated kinase 2 promotes pancreatic cancer growth and metastasis Retraction in /10.3892/ol.2023.13949

Guo‑Wang Yao, Jing‑Rui Bai, Da‑Peng Zhang
Pages: 3709-3718
Published online on: 14 February 2019

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Article Open Access

Inhibition of the PI3K/AKT signaling pathway sensitizes diffuse large B‑cell lymphoma cells to treatment with proteasome inhibitors via suppression of BAG3

Ting Yuan, Feng Zhang, Xiangxiang Zhou, Ying Li, Ya Zhang, Yangyang Xu, Xin Wang
Pages: 3719-3726
Published online on: 08 February 2019

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Article Open Access

Regulatory effect of Act1 on the BAFF pathway in B‑cell malignancy

Xiao‑Jun Ge, Yong‑Lun Wang, Yang Ping Wu, Zhong‑Xin Feng, Lan Liu, Mei Yong Li, Jun‑Yao Jiang
Pages: 3727-3734
Published online on: 18 February 2019

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Article Open Access

Silencing of EPHB2 promotes the epithelial‑mesenchymal transition of skin squamous cell carcinoma‑derived A431 cells

Yoshinori Inagaki, Tomohiko Tokunaga, Mitsuru Yanai, Dan Wu, Jiyi Huang, Hiroki Nagase, Noboru Fukuda, Toshinori Ozaki, Masayoshi Soma, Kyoko Fujiwara
Pages: 3735-3742
Published online on: 06 February 2019

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Article Open Access

Analysis of the promoter region of the human miR‑32 gene in colorectal cancer

Weiyun Wu, Wenkai Tan, Shicai Ye, Yu Zhou, Juanhua Quan
Pages: 3743-3750
Published online on: 14 February 2019

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Article Open Access

Identification of key pathways and candidate genes in pancreatic ductal adenocarcinoma using bioinformatics analysis

Yiping He, Yan Liu, Jianping Gong, Changan Liu, Hua Zhang, Hao Wu
Pages: 3751-3764
Published online on: 14 February 2019

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Article Open Access

Differential microRNA expression profiles determined by next‑generation sequencing in three fulvestrant‑resistant human breast cancer cell lines

Juan Guo, Keli He, Hui Zeng, Yu Shi, Peng Ye, Qian Zhou, Zhongya Pan, Xinghua Long
Pages: 3765-3776
Published online on: 21 February 2019

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Article Open Access

Application value of nursing intervention combined with early nutritional support in preventive stoma reversion of low rectal cancer

Xinmei Ye, Dandan He, Jie Zhao, Yuqing Lei, Qiuqiong Yao, Hui Wang
Pages: 3777-3782
Published online on: 19 February 2019

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Article Open Access

Resveratrol induces p53 in colorectal cancer through SET7/9

Zhonglun Liu, Xiaohong Wu, Jingjing Lv, Hui Sun, Feiqin Zhou
Pages: 3783-3789
Published online on: 13 February 2019

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Article Open Access

miR‑944 inhibits lung adenocarcinoma tumorigenesis by targeting STAT1 interaction

Jing Chun An, Han‑Bing Shi, Wen‑Bo Hao, Kun Zhu, Bo Ma
Pages: 3790-3798
Published online on: 18 February 2019

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Article Open Access

Isolation of circulating tumor cells and detection of EGFR mutations in patients with non‑small‑cell lung cancer

Qi Zhang, Jingying Nong, Jinghui Wang, Zhuohong Yan, Ling Yi, Xin Gao, Zhidong Liu, Hongtao Zhang, Shucai Zhang
Pages: 3799-3807
Published online on: 05 February 2019

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Article Open Access

Determination of the complexity and diversity of the TCR β‑chain CDR3 repertoire in bladder cancer using high‑throughput sequencing

Jingsheng Ma, Guoping Sun, Peng Zhu, Song Liu, Minglin Ou, Zhiqiang Chen, Chang Zou, Frank Leing Chan, Yong Dai, Weiguo Sui
Pages: 3808-3816
Published online on: 05 February 2019

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Article Open Access

Isolation of circulating tumor cells in patients undergoing surgery for esophageal cancer and a specific confirmation method. Corrigendum in /10.3892/ol.2019.10878

Yunpeng Zhao, Shukang Zhao, Yingjie Chen, Xiaopeng Dong, Chuanliang Peng, Qifeng Sun, Lei Shan, Zhendan Wang, Xiaogang Zhao
Pages: 3817-3825
Published online on: 06 February 2019

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Article Open Access

p53 overexpression is a prognosticator of poor outcome in esophageal cancer

Nathaniel Melling, Sonja Norrenbrock, Martina Kluth, Ronald Simon, Claudia Hube‑Magg, Stefan Steurer, Andrea Hinsch, Eike Burandt, Frank Jacobsen, Waldemar Wilczak, Alexander Quaas, Maximillian Bockhorn, Katharina Grupp, Michael Tachezy, Jakob Izbicki, Guido Sauter, Florian Gebauer
Pages: 3826-3834
Published online on: 06 February 2019

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Article Open Access

miR‑140‑3p inhibits breast cancer proliferation and migration by directly regulating the expression of tripartite motif 28

Yu Zhou, Bo Wang, Yu Wang, Gaohui Chen, Qixin Lian, Haidong Wang
Pages: 3835-3841
Published online on: 13 February 2019

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Article Open Access

Luteolin inhibits cell cycle progression and induces apoptosis of breast cancer cells through downregulation of human telomerase reverse transcriptase

Liming Huang, Ketao Jin, Huanrong Lan
Pages: 3842-3850
Published online on: 19 February 2019

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Article Open Access

Expression patterns and the prognostic value of the SMYD family members in human breast carcinoma using integrative bioinformatics analysis

Jianping Song, Yanfeng Liu, Qian Chen, Jinhuan Yang, Zhengchen Jiang, Hao Zhang, Zhaojian Liu, Bin Jin
Pages: 3851-3861
Published online on: 19 February 2019

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Case Report Open Access

Small bowel perforation with multiple intestinal metastases from lung carcinoma: A case report

Evangelos P. Misiakos, Alina‑Roxani Gouloumi, Dimitrios Schizas, Vasileia Damaskou, Dimitrios Tsapralis, Frederick‑Anthony Farrugia, Nikolaos Machairas, Dimitrios Papaconstantinou, Ariadni Tzaneti, Anastasios Machairas
Pages: 3862-3866
Published online on: 12 February 2019

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Article Open Access

Measurement of morphological parameters of giant cell tumor of bone in the knee

Lin Guo, Peng Jia, Yong‑Cheng Hu, Man Sun, Zhi Wang, Xue‑Ning Zhang, Jun Miao
Pages: 3867-3873
Published online on: 21 February 2019

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Article Open Access

The long non‑coding RNA LINC00460 predicts the prognosis and promotes the proliferation and migration of cells in bladder urothelial carcinoma

Lijie Wen, Xiling Zhang, Jing Bian, Li Han, Haibo Huang, Miao He, Minjie Wei, Ping Wang
Pages: 3874-3880
Published online on: 07 February 2019

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Article Open Access

Gene expression profile analysis of ENO1 knockdown in gastric cancer cell line MGC‑803

Zhigang Huang, Bode Lin, Haiyan Pan, Jinlin Du, Rongwei He, Shizhuo Zhang, Ping Ouyang
Pages: 3881-3889
Published online on: 19 February 2019

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Article Open Access

Tumor response to irinotecan is associated with CYP3A5 expression in colorectal cancer

Emanuel Buck, Martin Sprick, Matthias M. Gaida, Carsten Grüllich, Tim Frederik Weber, Esther Herpel, Thomas Bruckner, Ronald Koschny
Pages: 3890-3898
Published online on: 14 February 2019

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Case Report Open Access

Primary malignant gastrointestinal neuroectodermal tumor occurring in the ileum with intra‑abdominal granulomatous nodules: A case report and review of the literature

Gao‑Xiang Huang, Qiu‑Yue Chen, Ling‑Ling Zhong, Hao Chen, Hai‑Peng Zhang, Xiao‑Fen Liu, Fang Tang
Pages: 3899-3909
Published online on: 21 February 2019

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Article Open Access

Expression of total and phospho 4EBP1 in metastatic and non‑metastatic renal cell carcinoma

Sei Naito, Osamu Ichiyanagi, Hiromi Ito, Takanobu Kabasawa, Hidenori Kanno, Takafumi Narisawa, Hiroki Fukuhara, Mayu Yagi, Yuta Kurota, Atsushi Yamagishi, Toshihiko Sakurai, Hayato Nishida, Hisashi Kawazoe, Takuya Yamanobe, Tomoyuki Kato, Peter Makhov, Vladimir M. Kolenko, Mitsunori Yamakawa, Norihiko Tsuchiya
Pages: 3910-3918
Published online on: 12 February 2019

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Article Open Access

Clinical value of miRNA‑122 in the diagnosis and prognosis of various types of cancer

Meiyu Dai, Limin Li, Xue Qin
Pages: 3919-3929
Published online on: 07 February 2019

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Article

Phase I study of preoperative chemoradiotherapy with sequential oxaliplatin and irinotecan with S‑1 for locally advanced rectal cancer

Hiroyuki Fujikawa, Yuji Toiyama, Yasuhiro Inoue, Yusuke Omura, Shozo Ide, Takahito Kitajima, Hiromi Yasuda, Yoshinaga Okugawa, Yoshiki Okita, Shigeyuki Yoshiyama, Junichiro Hiro, Minako Kobayashi, Masaki Ohi, Toshimitsu Araki, Masato Kusunoki
Pages: 3930-3936
Published online on: 08 February 2019

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Article

Immunohistochemical expression and clinicopathological assessment of the cancer testis antigens NY‑ESO‑1 and MAGE‑A4 in high‑grade soft‑tissue sarcoma

Takuya Kakimoto, Akihiko Matsumine, Shinichi Kageyama, Kunihiro Asanuma, Takao Matsubara, Tomoki Nakamura, Takahiro Iino, Hiroaki Ikeda, Hiroshi Shiku, Akihiro Sudo
Pages: 3937-3943
Published online on: 14 February 2019

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Article

Upregulation of FoxP4 in HCC promotes migration and invasion through regulation of EMT

Gang Zhang, Guangye Zhang
Pages: 3944-3951
Published online on: 19 February 2019

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Article

Characteristics of temperature changes in photothermal therapy induced by combined application of indocyanine green and laser

Shan Long, Yuanyuan Xu, Feifan Zhou, Bo Wang, Yunning Yang, Yan Fu, Nan Du, Xiaosong Li
Pages: 3952-3959
Published online on: 20 February 2019

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Article

Association of an miR‑502‑binding site polymorphism in the 3'‑untranslated region of SET8 with colorectal cancer

Shuang Liu, Hailing Dong, Jianhua Wu, Cuiju Wang
Pages: 3960-3964
Published online on: 07 February 2019

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Article

MicroRNA‑193b acts as a tumor suppressor gene in human esophageal squamous cell carcinoma via target regulation of KRAS

Min Kang, Yan Li, Shengtao Zhu, Shutian Zhang, Shuilong Guo, Peng Li
Pages: 3965-3973
Published online on: 13 February 2019

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Article

Expression of integrin α‑6 is associated with multi drug resistance and prognosis in ovarian cancer

Luwei Wei, Fuqiang Yin, Changxian Chen, Li Li
Pages: 3974-3980
Published online on: 20 February 2019

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Article

Inhibition of tumor growth and angiogenesis of tamoxifen‑resistant breast cancer cells by ruxolitinib, a selective JAK2 inhibitor

Ji Won Kim, Jaya Gautam, Ji Eun Kim, Jung‑Ae Kim, Keon Wook Kang
Pages: 3981-3989
Published online on: 20 February 2019

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Article

Application of Micro‑Tech stents in malignant carinal stenosis

Jin‑Mu Niu, Jie Zhang, Xiao‑Jian Qiu, Juan Wang, Ying‑Hua Pei, Yu‑Ling Wang, Ting Wang
Pages: 3990-3996
Published online on: 19 February 2019

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Article

Surgical lung biopsy in onco‑hematological patients with diffuse pulmonary infiltrates and mechanical ventilation in the ICU

Eduardo Mantovani Cardoso, Alexandre Galvão Bueno, Daniel Augusto Pavan, Ademar Dantas Cunha, Raysa Cristina Schmidt, Péricles A.D. Duarte
Pages: 3997-4003
Published online on: 21 February 2019

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Article

Prognostic impact of tumor‑infiltrating CD276/Foxp3‑positive lymphocytes and associated circulating cytokines in patients undergoing radical nephrectomy for localized renal cell carcinoma

Kota Iida, Makito Miyake, Kenta Onishi, Shunta Hori, Yosuke Morizawa, Daisuke Gotoh, Yoshitaka Itami, Sayuri Onishi, Yasushi Nakai, Satoshi Anai, Nobumichi Tanaka, Kiyohide Fujimoto
Pages: 4004-4010
Published online on: 20 February 2019

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Case Report

Metastatic renal cell carcinoma regains sensitivity to tyrosine kinase inhibitor after nivolumab treatment: A case report

Takeshi Azuma, Tohru Sugihara, Sachi Honda, Uran Yoshizaki, Fusako Niimi, Ibuki Tsuru, Haruki Kume
Pages: 4011-4015
Published online on: 08 February 2019

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Article

NOTCH1, SF3B1, MDM2 and MYD88 mutations in patients with chronic lymphocytic leukemia

Yosra Maleki, Zahra Alahbakhshi, Zahra Heidari, Mohammad‑Taher Moradi, Ziba Rahimi, Kheirolah Yari, Zohreh Rahimi, Mozafar Aznab, Meisam Ahmadi‑Khajevand, Fariborz Bahremand
Pages: 4016-4023
Published online on: 19 February 2019

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Article

Enhanced targeting of prostate cancer‑initiating cells by salinomycin‑encapsulated lipid‑PLGA nanoparticles linked with CD44 antibodies

Jun Wei, Jin Sun, Yu Liu
Pages: 4024-4033
Published online on: 19 February 2019

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Article

Hypoxia‑inducible factor-1 signaling pathway influences the sensitivity of HCC827 cells to gefitinib

Qian Jin, Jianying Zhou, Xianrong Xu, Feihua Huang, Weihua Xu
Pages: 4034-4043
Published online on: 07 February 2019

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Retraction Open Access

[Retracted] Identification of circulating tumor cells with EML4‑ALK translocation using fluorescence in situ hybridization in advanced ALK‑positive patients with lung cancer

Young Hun Kim, Eunjoo Hwang, Hye Seon Lee, Ji‑Hyun Uh, Myoung Shin Kim, Byung Hee Jeon
Pages: 4044-4044
Published online on: 12 February 2019

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Journal Cover
July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu-Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing
Article Number: 321
Published online on: 02 June 2026

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Correction Open Access

[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 320
Published online on: 02 June 2026

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Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Article Open Access

Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Article Open Access

Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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Article Open Access

D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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August-2026 Volume 32 Issue 2

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Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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