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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2019 Volume 17 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

F‑box/WD‑40 repeat‑containing protein 7: A potential target in the progression and treatment of gastrointestinal malignancy (Review)

Yizhi Wang, Yang An, Yi Ma, Junchao Guo
Pages: 3625-3634
Published online on: 13 February 2019

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Review

A research update on the anticancer effects of bufalin and its derivatives (Review)

Yu‑Long Lan, Jia‑Cheng Lou, Xue‑Wen Jiang, Xun Wang, Jin‑Shan Xing, Shao Li, Bo Zhang
Pages: 3635-3640
Published online on: 21 February 2019

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Article Open Access

4‑Dimensional computed tomography analysis of clinical target volume displacement in adjuvant radiation of patients with gastric cancer and its implication on radiotherapy

Jin Peng, Jun Gong, Xiaoyong Wang, Jingjing Mou, Hui Xu, Jing Dai, Fuxiang Zhou, Yunfeng Zhou
Pages: 3641-3648
Published online on: 13 February 2019

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Article Open Access

Stratification of patients with colorectal cancer without the recorded family history

Ivana Kašubová, Michal Kalman, Karin Jašek, Tatiana Burjanivová, Bibiana Malicherová, Andrea Vaňochová, Sandra Meršaková, Zora Lasabová, Lukáš Plank
Pages: 3649-3656
Published online on: 06 February 2019

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Article Open Access

The oncogenic role of Wnt10a in colorectal cancer through activation of canonical Wnt/β‑catenin signaling

Jinlong Li, Zhaoli Zhang, Lixue Wang, Yongchen Zhang
Pages: 3657-3664
Published online on: 13 February 2019

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Article Open Access

Curative effect of endostar combined with oxaliplatin in the treatment of primary hepatic carcinoma and its influence on immune cells

Changjiang Lei, Defa Ren, Meixia Fu, Chuantao Sun, Hong Ren, Qingyun Pan, Yuan Li
Pages: 3665-3670
Published online on: 06 February 2019

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Article Open Access

Self‑made thoracic needled suspending device with a snare: An excellent aid for uniportal video‑assisted thoracic lobectomy and segmentectomy for lung cancer Corrigendum in /10.3892/ol.2020.11409

Shanlei Wang, Chuizheng Meng, Zhongmin Jiang, Diego Gonzalez-Rivas, Junfen Ruan, Wei Xu, Chuanping Liu, Lei Zhang, Guogang Gao, Ge Yu, Hezhi Teng, Jin Ju
Pages: 3671-3676
Published online on: 12 February 2019

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Article Open Access

In silico detection of potential prognostic circRNAs through a re‑annotation strategy in ovarian cancer

Qiuyan Guo, Yanan He, Liyuan Sun, Congcong Kong, Yan Cheng, Guangmei Zhang
Pages: 3677-3686
Published online on: 06 February 2019

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Article Open Access

Expression and prognostic significance of Fanconi anemia group D2 protein and breast cancer type 1 susceptibility protein in familial and sporadic breast cancer

Liang Feng, Feng Jin
Pages: 3687-3700
Published online on: 18 February 2019

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Article Open Access

Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines

Yu Li, Xin Chen, Yong Cui, Qun Wei, Suiyun Chen, Xiaofang Wang
Pages: 3701-3708
Published online on: 21 February 2019

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Article Open Access

P21 activated kinase 2 promotes pancreatic cancer growth and metastasis Retraction in /10.3892/ol.2023.13949

Guo‑Wang Yao, Jing‑Rui Bai, Da‑Peng Zhang
Pages: 3709-3718
Published online on: 14 February 2019

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Article Open Access

Inhibition of the PI3K/AKT signaling pathway sensitizes diffuse large B‑cell lymphoma cells to treatment with proteasome inhibitors via suppression of BAG3

Ting Yuan, Feng Zhang, Xiangxiang Zhou, Ying Li, Ya Zhang, Yangyang Xu, Xin Wang
Pages: 3719-3726
Published online on: 08 February 2019

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Article Open Access

Regulatory effect of Act1 on the BAFF pathway in B‑cell malignancy

Xiao‑Jun Ge, Yong‑Lun Wang, Yang Ping Wu, Zhong‑Xin Feng, Lan Liu, Mei Yong Li, Jun‑Yao Jiang
Pages: 3727-3734
Published online on: 18 February 2019

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Article Open Access

Silencing of EPHB2 promotes the epithelial‑mesenchymal transition of skin squamous cell carcinoma‑derived A431 cells

Yoshinori Inagaki, Tomohiko Tokunaga, Mitsuru Yanai, Dan Wu, Jiyi Huang, Hiroki Nagase, Noboru Fukuda, Toshinori Ozaki, Masayoshi Soma, Kyoko Fujiwara
Pages: 3735-3742
Published online on: 06 February 2019

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Article Open Access

Analysis of the promoter region of the human miR‑32 gene in colorectal cancer

Weiyun Wu, Wenkai Tan, Shicai Ye, Yu Zhou, Juanhua Quan
Pages: 3743-3750
Published online on: 14 February 2019

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Article Open Access

Identification of key pathways and candidate genes in pancreatic ductal adenocarcinoma using bioinformatics analysis

Yiping He, Yan Liu, Jianping Gong, Changan Liu, Hua Zhang, Hao Wu
Pages: 3751-3764
Published online on: 14 February 2019

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Article Open Access

Differential microRNA expression profiles determined by next‑generation sequencing in three fulvestrant‑resistant human breast cancer cell lines

Juan Guo, Keli He, Hui Zeng, Yu Shi, Peng Ye, Qian Zhou, Zhongya Pan, Xinghua Long
Pages: 3765-3776
Published online on: 21 February 2019

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Article Open Access

Application value of nursing intervention combined with early nutritional support in preventive stoma reversion of low rectal cancer

Xinmei Ye, Dandan He, Jie Zhao, Yuqing Lei, Qiuqiong Yao, Hui Wang
Pages: 3777-3782
Published online on: 19 February 2019

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Article Open Access

Resveratrol induces p53 in colorectal cancer through SET7/9

Zhonglun Liu, Xiaohong Wu, Jingjing Lv, Hui Sun, Feiqin Zhou
Pages: 3783-3789
Published online on: 13 February 2019

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Article Open Access

miR‑944 inhibits lung adenocarcinoma tumorigenesis by targeting STAT1 interaction

Jing Chun An, Han‑Bing Shi, Wen‑Bo Hao, Kun Zhu, Bo Ma
Pages: 3790-3798
Published online on: 18 February 2019

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Article Open Access

Isolation of circulating tumor cells and detection of EGFR mutations in patients with non‑small‑cell lung cancer

Qi Zhang, Jingying Nong, Jinghui Wang, Zhuohong Yan, Ling Yi, Xin Gao, Zhidong Liu, Hongtao Zhang, Shucai Zhang
Pages: 3799-3807
Published online on: 05 February 2019

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Article Open Access

Determination of the complexity and diversity of the TCR β‑chain CDR3 repertoire in bladder cancer using high‑throughput sequencing

Jingsheng Ma, Guoping Sun, Peng Zhu, Song Liu, Minglin Ou, Zhiqiang Chen, Chang Zou, Frank Leing Chan, Yong Dai, Weiguo Sui
Pages: 3808-3816
Published online on: 05 February 2019

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Article Open Access

Isolation of circulating tumor cells in patients undergoing surgery for esophageal cancer and a specific confirmation method. Corrigendum in /10.3892/ol.2019.10878

Yunpeng Zhao, Shukang Zhao, Yingjie Chen, Xiaopeng Dong, Chuanliang Peng, Qifeng Sun, Lei Shan, Zhendan Wang, Xiaogang Zhao
Pages: 3817-3825
Published online on: 06 February 2019

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Article Open Access

p53 overexpression is a prognosticator of poor outcome in esophageal cancer

Nathaniel Melling, Sonja Norrenbrock, Martina Kluth, Ronald Simon, Claudia Hube‑Magg, Stefan Steurer, Andrea Hinsch, Eike Burandt, Frank Jacobsen, Waldemar Wilczak, Alexander Quaas, Maximillian Bockhorn, Katharina Grupp, Michael Tachezy, Jakob Izbicki, Guido Sauter, Florian Gebauer
Pages: 3826-3834
Published online on: 06 February 2019

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Article Open Access

miR‑140‑3p inhibits breast cancer proliferation and migration by directly regulating the expression of tripartite motif 28

Yu Zhou, Bo Wang, Yu Wang, Gaohui Chen, Qixin Lian, Haidong Wang
Pages: 3835-3841
Published online on: 13 February 2019

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Article Open Access

Luteolin inhibits cell cycle progression and induces apoptosis of breast cancer cells through downregulation of human telomerase reverse transcriptase

Liming Huang, Ketao Jin, Huanrong Lan
Pages: 3842-3850
Published online on: 19 February 2019

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Article Open Access

Expression patterns and the prognostic value of the SMYD family members in human breast carcinoma using integrative bioinformatics analysis

Jianping Song, Yanfeng Liu, Qian Chen, Jinhuan Yang, Zhengchen Jiang, Hao Zhang, Zhaojian Liu, Bin Jin
Pages: 3851-3861
Published online on: 19 February 2019

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Case Report Open Access

Small bowel perforation with multiple intestinal metastases from lung carcinoma: A case report

Evangelos P. Misiakos, Alina‑Roxani Gouloumi, Dimitrios Schizas, Vasileia Damaskou, Dimitrios Tsapralis, Frederick‑Anthony Farrugia, Nikolaos Machairas, Dimitrios Papaconstantinou, Ariadni Tzaneti, Anastasios Machairas
Pages: 3862-3866
Published online on: 12 February 2019

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Article Open Access

Measurement of morphological parameters of giant cell tumor of bone in the knee

Lin Guo, Peng Jia, Yong‑Cheng Hu, Man Sun, Zhi Wang, Xue‑Ning Zhang, Jun Miao
Pages: 3867-3873
Published online on: 21 February 2019

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Article Open Access

The long non‑coding RNA LINC00460 predicts the prognosis and promotes the proliferation and migration of cells in bladder urothelial carcinoma

Lijie Wen, Xiling Zhang, Jing Bian, Li Han, Haibo Huang, Miao He, Minjie Wei, Ping Wang
Pages: 3874-3880
Published online on: 07 February 2019

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Article Open Access

Gene expression profile analysis of ENO1 knockdown in gastric cancer cell line MGC‑803

Zhigang Huang, Bode Lin, Haiyan Pan, Jinlin Du, Rongwei He, Shizhuo Zhang, Ping Ouyang
Pages: 3881-3889
Published online on: 19 February 2019

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Article Open Access

Tumor response to irinotecan is associated with CYP3A5 expression in colorectal cancer

Emanuel Buck, Martin Sprick, Matthias M. Gaida, Carsten Grüllich, Tim Frederik Weber, Esther Herpel, Thomas Bruckner, Ronald Koschny
Pages: 3890-3898
Published online on: 14 February 2019

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Case Report Open Access

Primary malignant gastrointestinal neuroectodermal tumor occurring in the ileum with intra‑abdominal granulomatous nodules: A case report and review of the literature

Gao‑Xiang Huang, Qiu‑Yue Chen, Ling‑Ling Zhong, Hao Chen, Hai‑Peng Zhang, Xiao‑Fen Liu, Fang Tang
Pages: 3899-3909
Published online on: 21 February 2019

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Article Open Access

Expression of total and phospho 4EBP1 in metastatic and non‑metastatic renal cell carcinoma

Sei Naito, Osamu Ichiyanagi, Hiromi Ito, Takanobu Kabasawa, Hidenori Kanno, Takafumi Narisawa, Hiroki Fukuhara, Mayu Yagi, Yuta Kurota, Atsushi Yamagishi, Toshihiko Sakurai, Hayato Nishida, Hisashi Kawazoe, Takuya Yamanobe, Tomoyuki Kato, Peter Makhov, Vladimir M. Kolenko, Mitsunori Yamakawa, Norihiko Tsuchiya
Pages: 3910-3918
Published online on: 12 February 2019

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Article Open Access

Clinical value of miRNA‑122 in the diagnosis and prognosis of various types of cancer

Meiyu Dai, Limin Li, Xue Qin
Pages: 3919-3929
Published online on: 07 February 2019

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Article

Phase I study of preoperative chemoradiotherapy with sequential oxaliplatin and irinotecan with S‑1 for locally advanced rectal cancer

Hiroyuki Fujikawa, Yuji Toiyama, Yasuhiro Inoue, Yusuke Omura, Shozo Ide, Takahito Kitajima, Hiromi Yasuda, Yoshinaga Okugawa, Yoshiki Okita, Shigeyuki Yoshiyama, Junichiro Hiro, Minako Kobayashi, Masaki Ohi, Toshimitsu Araki, Masato Kusunoki
Pages: 3930-3936
Published online on: 08 February 2019

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Article

Immunohistochemical expression and clinicopathological assessment of the cancer testis antigens NY‑ESO‑1 and MAGE‑A4 in high‑grade soft‑tissue sarcoma

Takuya Kakimoto, Akihiko Matsumine, Shinichi Kageyama, Kunihiro Asanuma, Takao Matsubara, Tomoki Nakamura, Takahiro Iino, Hiroaki Ikeda, Hiroshi Shiku, Akihiro Sudo
Pages: 3937-3943
Published online on: 14 February 2019

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Article

Upregulation of FoxP4 in HCC promotes migration and invasion through regulation of EMT

Gang Zhang, Guangye Zhang
Pages: 3944-3951
Published online on: 19 February 2019

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Article

Characteristics of temperature changes in photothermal therapy induced by combined application of indocyanine green and laser

Shan Long, Yuanyuan Xu, Feifan Zhou, Bo Wang, Yunning Yang, Yan Fu, Nan Du, Xiaosong Li
Pages: 3952-3959
Published online on: 20 February 2019

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Article

Association of an miR‑502‑binding site polymorphism in the 3'‑untranslated region of SET8 with colorectal cancer

Shuang Liu, Hailing Dong, Jianhua Wu, Cuiju Wang
Pages: 3960-3964
Published online on: 07 February 2019

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Article

MicroRNA‑193b acts as a tumor suppressor gene in human esophageal squamous cell carcinoma via target regulation of KRAS

Min Kang, Yan Li, Shengtao Zhu, Shutian Zhang, Shuilong Guo, Peng Li
Pages: 3965-3973
Published online on: 13 February 2019

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Article

Expression of integrin α‑6 is associated with multi drug resistance and prognosis in ovarian cancer

Luwei Wei, Fuqiang Yin, Changxian Chen, Li Li
Pages: 3974-3980
Published online on: 20 February 2019

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Article

Inhibition of tumor growth and angiogenesis of tamoxifen‑resistant breast cancer cells by ruxolitinib, a selective JAK2 inhibitor

Ji Won Kim, Jaya Gautam, Ji Eun Kim, Jung‑Ae Kim, Keon Wook Kang
Pages: 3981-3989
Published online on: 20 February 2019

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Article

Application of Micro‑Tech stents in malignant carinal stenosis

Jin‑Mu Niu, Jie Zhang, Xiao‑Jian Qiu, Juan Wang, Ying‑Hua Pei, Yu‑Ling Wang, Ting Wang
Pages: 3990-3996
Published online on: 19 February 2019

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Article

Surgical lung biopsy in onco‑hematological patients with diffuse pulmonary infiltrates and mechanical ventilation in the ICU

Eduardo Mantovani Cardoso, Alexandre Galvão Bueno, Daniel Augusto Pavan, Ademar Dantas Cunha, Raysa Cristina Schmidt, Péricles A.D. Duarte
Pages: 3997-4003
Published online on: 21 February 2019

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Article

Prognostic impact of tumor‑infiltrating CD276/Foxp3‑positive lymphocytes and associated circulating cytokines in patients undergoing radical nephrectomy for localized renal cell carcinoma

Kota Iida, Makito Miyake, Kenta Onishi, Shunta Hori, Yosuke Morizawa, Daisuke Gotoh, Yoshitaka Itami, Sayuri Onishi, Yasushi Nakai, Satoshi Anai, Nobumichi Tanaka, Kiyohide Fujimoto
Pages: 4004-4010
Published online on: 20 February 2019

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Case Report

Metastatic renal cell carcinoma regains sensitivity to tyrosine kinase inhibitor after nivolumab treatment: A case report

Takeshi Azuma, Tohru Sugihara, Sachi Honda, Uran Yoshizaki, Fusako Niimi, Ibuki Tsuru, Haruki Kume
Pages: 4011-4015
Published online on: 08 February 2019

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Article

NOTCH1, SF3B1, MDM2 and MYD88 mutations in patients with chronic lymphocytic leukemia

Yosra Maleki, Zahra Alahbakhshi, Zahra Heidari, Mohammad‑Taher Moradi, Ziba Rahimi, Kheirolah Yari, Zohreh Rahimi, Mozafar Aznab, Meisam Ahmadi‑Khajevand, Fariborz Bahremand
Pages: 4016-4023
Published online on: 19 February 2019

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Article

Enhanced targeting of prostate cancer‑initiating cells by salinomycin‑encapsulated lipid‑PLGA nanoparticles linked with CD44 antibodies

Jun Wei, Jin Sun, Yu Liu
Pages: 4024-4033
Published online on: 19 February 2019

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Article

Hypoxia‑inducible factor-1 signaling pathway influences the sensitivity of HCC827 cells to gefitinib

Qian Jin, Jianying Zhou, Xianrong Xu, Feihua Huang, Weihua Xu
Pages: 4034-4043
Published online on: 07 February 2019

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Retraction Open Access

[Retracted] Identification of circulating tumor cells with EML4‑ALK translocation using fluorescence in situ hybridization in advanced ALK‑positive patients with lung cancer

Young Hun Kim, Eunjoo Hwang, Hye Seon Lee, Ji‑Hyun Uh, Myoung Shin Kim, Byung Hee Jeon
Pages: 4044-4044
Published online on: 12 February 2019

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Journal Cover
January-2026 Volume 31 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Case Report Open Access

Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Article Open Access

Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Article Open Access

Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Review Open Access

Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Review Open Access

Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Article Open Access

Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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Article Open Access

TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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Article

TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Review Open Access

Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Article Open Access

Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Case Report Open Access

Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Article Open Access

Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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Review Open Access

From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Review Open Access

Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Article Open Access

Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Review Open Access

Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Review Open Access

Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Article Open Access

Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Article Open Access

Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Review Open Access

Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Article Open Access

Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Article Open Access

Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Article Open Access

Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Article Open Access

Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Article Open Access

Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Article Open Access

Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Article Open Access

Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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Article Open Access

CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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