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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2019 Volume 17 Issue 4

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

F‑box/WD‑40 repeat‑containing protein 7: A potential target in the progression and treatment of gastrointestinal malignancy (Review)

Yizhi Wang, Yang An, Yi Ma, Junchao Guo
Pages: 3625-3634
Published online on: 13 February 2019

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Review

A research update on the anticancer effects of bufalin and its derivatives (Review)

Yu‑Long Lan, Jia‑Cheng Lou, Xue‑Wen Jiang, Xun Wang, Jin‑Shan Xing, Shao Li, Bo Zhang
Pages: 3635-3640
Published online on: 21 February 2019

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Article Open Access

4‑Dimensional computed tomography analysis of clinical target volume displacement in adjuvant radiation of patients with gastric cancer and its implication on radiotherapy

Jin Peng, Jun Gong, Xiaoyong Wang, Jingjing Mou, Hui Xu, Jing Dai, Fuxiang Zhou, Yunfeng Zhou
Pages: 3641-3648
Published online on: 13 February 2019

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Article Open Access

Stratification of patients with colorectal cancer without the recorded family history

Ivana Kašubová, Michal Kalman, Karin Jašek, Tatiana Burjanivová, Bibiana Malicherová, Andrea Vaňochová, Sandra Meršaková, Zora Lasabová, Lukáš Plank
Pages: 3649-3656
Published online on: 06 February 2019

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Article Open Access

The oncogenic role of Wnt10a in colorectal cancer through activation of canonical Wnt/β‑catenin signaling

Jinlong Li, Zhaoli Zhang, Lixue Wang, Yongchen Zhang
Pages: 3657-3664
Published online on: 13 February 2019

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Article Open Access

Curative effect of endostar combined with oxaliplatin in the treatment of primary hepatic carcinoma and its influence on immune cells

Changjiang Lei, Defa Ren, Meixia Fu, Chuantao Sun, Hong Ren, Qingyun Pan, Yuan Li
Pages: 3665-3670
Published online on: 06 February 2019

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Article Open Access

Self‑made thoracic needled suspending device with a snare: An excellent aid for uniportal video‑assisted thoracic lobectomy and segmentectomy for lung cancer Corrigendum in /10.3892/ol.2020.11409

Shanlei Wang, Chuizheng Meng, Zhongmin Jiang, Diego Gonzalez-Rivas, Junfen Ruan, Wei Xu, Chuanping Liu, Lei Zhang, Guogang Gao, Ge Yu, Hezhi Teng, Jin Ju
Pages: 3671-3676
Published online on: 12 February 2019

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Article Open Access

In silico detection of potential prognostic circRNAs through a re‑annotation strategy in ovarian cancer

Qiuyan Guo, Yanan He, Liyuan Sun, Congcong Kong, Yan Cheng, Guangmei Zhang
Pages: 3677-3686
Published online on: 06 February 2019

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Article Open Access

Expression and prognostic significance of Fanconi anemia group D2 protein and breast cancer type 1 susceptibility protein in familial and sporadic breast cancer

Liang Feng, Feng Jin
Pages: 3687-3700
Published online on: 18 February 2019

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Article Open Access

Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines

Yu Li, Xin Chen, Yong Cui, Qun Wei, Suiyun Chen, Xiaofang Wang
Pages: 3701-3708
Published online on: 21 February 2019

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Article Open Access

P21 activated kinase 2 promotes pancreatic cancer growth and metastasis Retraction in /10.3892/ol.2023.13949

Guo‑Wang Yao, Jing‑Rui Bai, Da‑Peng Zhang
Pages: 3709-3718
Published online on: 14 February 2019

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Article Open Access

Inhibition of the PI3K/AKT signaling pathway sensitizes diffuse large B‑cell lymphoma cells to treatment with proteasome inhibitors via suppression of BAG3

Ting Yuan, Feng Zhang, Xiangxiang Zhou, Ying Li, Ya Zhang, Yangyang Xu, Xin Wang
Pages: 3719-3726
Published online on: 08 February 2019

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Article Open Access

Regulatory effect of Act1 on the BAFF pathway in B‑cell malignancy

Xiao‑Jun Ge, Yong‑Lun Wang, Yang Ping Wu, Zhong‑Xin Feng, Lan Liu, Mei Yong Li, Jun‑Yao Jiang
Pages: 3727-3734
Published online on: 18 February 2019

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Article Open Access

Silencing of EPHB2 promotes the epithelial‑mesenchymal transition of skin squamous cell carcinoma‑derived A431 cells

Yoshinori Inagaki, Tomohiko Tokunaga, Mitsuru Yanai, Dan Wu, Jiyi Huang, Hiroki Nagase, Noboru Fukuda, Toshinori Ozaki, Masayoshi Soma, Kyoko Fujiwara
Pages: 3735-3742
Published online on: 06 February 2019

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Article Open Access

Analysis of the promoter region of the human miR‑32 gene in colorectal cancer

Weiyun Wu, Wenkai Tan, Shicai Ye, Yu Zhou, Juanhua Quan
Pages: 3743-3750
Published online on: 14 February 2019

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Article Open Access

Identification of key pathways and candidate genes in pancreatic ductal adenocarcinoma using bioinformatics analysis

Yiping He, Yan Liu, Jianping Gong, Changan Liu, Hua Zhang, Hao Wu
Pages: 3751-3764
Published online on: 14 February 2019

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Article Open Access

Differential microRNA expression profiles determined by next‑generation sequencing in three fulvestrant‑resistant human breast cancer cell lines

Juan Guo, Keli He, Hui Zeng, Yu Shi, Peng Ye, Qian Zhou, Zhongya Pan, Xinghua Long
Pages: 3765-3776
Published online on: 21 February 2019

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Article Open Access

Application value of nursing intervention combined with early nutritional support in preventive stoma reversion of low rectal cancer

Xinmei Ye, Dandan He, Jie Zhao, Yuqing Lei, Qiuqiong Yao, Hui Wang
Pages: 3777-3782
Published online on: 19 February 2019

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Article Open Access

Resveratrol induces p53 in colorectal cancer through SET7/9

Zhonglun Liu, Xiaohong Wu, Jingjing Lv, Hui Sun, Feiqin Zhou
Pages: 3783-3789
Published online on: 13 February 2019

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Article Open Access

miR‑944 inhibits lung adenocarcinoma tumorigenesis by targeting STAT1 interaction

Jing Chun An, Han‑Bing Shi, Wen‑Bo Hao, Kun Zhu, Bo Ma
Pages: 3790-3798
Published online on: 18 February 2019

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Article Open Access

Isolation of circulating tumor cells and detection of EGFR mutations in patients with non‑small‑cell lung cancer

Qi Zhang, Jingying Nong, Jinghui Wang, Zhuohong Yan, Ling Yi, Xin Gao, Zhidong Liu, Hongtao Zhang, Shucai Zhang
Pages: 3799-3807
Published online on: 05 February 2019

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Article Open Access

Determination of the complexity and diversity of the TCR β‑chain CDR3 repertoire in bladder cancer using high‑throughput sequencing

Jingsheng Ma, Guoping Sun, Peng Zhu, Song Liu, Minglin Ou, Zhiqiang Chen, Chang Zou, Frank Leing Chan, Yong Dai, Weiguo Sui
Pages: 3808-3816
Published online on: 05 February 2019

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Article Open Access

Isolation of circulating tumor cells in patients undergoing surgery for esophageal cancer and a specific confirmation method. Corrigendum in /10.3892/ol.2019.10878

Yunpeng Zhao, Shukang Zhao, Yingjie Chen, Xiaopeng Dong, Chuanliang Peng, Qifeng Sun, Lei Shan, Zhendan Wang, Xiaogang Zhao
Pages: 3817-3825
Published online on: 06 February 2019

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Article Open Access

p53 overexpression is a prognosticator of poor outcome in esophageal cancer

Nathaniel Melling, Sonja Norrenbrock, Martina Kluth, Ronald Simon, Claudia Hube‑Magg, Stefan Steurer, Andrea Hinsch, Eike Burandt, Frank Jacobsen, Waldemar Wilczak, Alexander Quaas, Maximillian Bockhorn, Katharina Grupp, Michael Tachezy, Jakob Izbicki, Guido Sauter, Florian Gebauer
Pages: 3826-3834
Published online on: 06 February 2019

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Article Open Access

miR‑140‑3p inhibits breast cancer proliferation and migration by directly regulating the expression of tripartite motif 28

Yu Zhou, Bo Wang, Yu Wang, Gaohui Chen, Qixin Lian, Haidong Wang
Pages: 3835-3841
Published online on: 13 February 2019

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Article Open Access

Luteolin inhibits cell cycle progression and induces apoptosis of breast cancer cells through downregulation of human telomerase reverse transcriptase

Liming Huang, Ketao Jin, Huanrong Lan
Pages: 3842-3850
Published online on: 19 February 2019

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Article Open Access

Expression patterns and the prognostic value of the SMYD family members in human breast carcinoma using integrative bioinformatics analysis

Jianping Song, Yanfeng Liu, Qian Chen, Jinhuan Yang, Zhengchen Jiang, Hao Zhang, Zhaojian Liu, Bin Jin
Pages: 3851-3861
Published online on: 19 February 2019

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Case Report Open Access

Small bowel perforation with multiple intestinal metastases from lung carcinoma: A case report

Evangelos P. Misiakos, Alina‑Roxani Gouloumi, Dimitrios Schizas, Vasileia Damaskou, Dimitrios Tsapralis, Frederick‑Anthony Farrugia, Nikolaos Machairas, Dimitrios Papaconstantinou, Ariadni Tzaneti, Anastasios Machairas
Pages: 3862-3866
Published online on: 12 February 2019

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Article Open Access

Measurement of morphological parameters of giant cell tumor of bone in the knee

Lin Guo, Peng Jia, Yong‑Cheng Hu, Man Sun, Zhi Wang, Xue‑Ning Zhang, Jun Miao
Pages: 3867-3873
Published online on: 21 February 2019

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Article Open Access

The long non‑coding RNA LINC00460 predicts the prognosis and promotes the proliferation and migration of cells in bladder urothelial carcinoma

Lijie Wen, Xiling Zhang, Jing Bian, Li Han, Haibo Huang, Miao He, Minjie Wei, Ping Wang
Pages: 3874-3880
Published online on: 07 February 2019

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Article Open Access

Gene expression profile analysis of ENO1 knockdown in gastric cancer cell line MGC‑803

Zhigang Huang, Bode Lin, Haiyan Pan, Jinlin Du, Rongwei He, Shizhuo Zhang, Ping Ouyang
Pages: 3881-3889
Published online on: 19 February 2019

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Article Open Access

Tumor response to irinotecan is associated with CYP3A5 expression in colorectal cancer

Emanuel Buck, Martin Sprick, Matthias M. Gaida, Carsten Grüllich, Tim Frederik Weber, Esther Herpel, Thomas Bruckner, Ronald Koschny
Pages: 3890-3898
Published online on: 14 February 2019

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Case Report Open Access

Primary malignant gastrointestinal neuroectodermal tumor occurring in the ileum with intra‑abdominal granulomatous nodules: A case report and review of the literature

Gao‑Xiang Huang, Qiu‑Yue Chen, Ling‑Ling Zhong, Hao Chen, Hai‑Peng Zhang, Xiao‑Fen Liu, Fang Tang
Pages: 3899-3909
Published online on: 21 February 2019

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Article Open Access

Expression of total and phospho 4EBP1 in metastatic and non‑metastatic renal cell carcinoma

Sei Naito, Osamu Ichiyanagi, Hiromi Ito, Takanobu Kabasawa, Hidenori Kanno, Takafumi Narisawa, Hiroki Fukuhara, Mayu Yagi, Yuta Kurota, Atsushi Yamagishi, Toshihiko Sakurai, Hayato Nishida, Hisashi Kawazoe, Takuya Yamanobe, Tomoyuki Kato, Peter Makhov, Vladimir M. Kolenko, Mitsunori Yamakawa, Norihiko Tsuchiya
Pages: 3910-3918
Published online on: 12 February 2019

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Article Open Access

Clinical value of miRNA‑122 in the diagnosis and prognosis of various types of cancer

Meiyu Dai, Limin Li, Xue Qin
Pages: 3919-3929
Published online on: 07 February 2019

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Article

Phase I study of preoperative chemoradiotherapy with sequential oxaliplatin and irinotecan with S‑1 for locally advanced rectal cancer

Hiroyuki Fujikawa, Yuji Toiyama, Yasuhiro Inoue, Yusuke Omura, Shozo Ide, Takahito Kitajima, Hiromi Yasuda, Yoshinaga Okugawa, Yoshiki Okita, Shigeyuki Yoshiyama, Junichiro Hiro, Minako Kobayashi, Masaki Ohi, Toshimitsu Araki, Masato Kusunoki
Pages: 3930-3936
Published online on: 08 February 2019

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Article

Immunohistochemical expression and clinicopathological assessment of the cancer testis antigens NY‑ESO‑1 and MAGE‑A4 in high‑grade soft‑tissue sarcoma

Takuya Kakimoto, Akihiko Matsumine, Shinichi Kageyama, Kunihiro Asanuma, Takao Matsubara, Tomoki Nakamura, Takahiro Iino, Hiroaki Ikeda, Hiroshi Shiku, Akihiro Sudo
Pages: 3937-3943
Published online on: 14 February 2019

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Article

Upregulation of FoxP4 in HCC promotes migration and invasion through regulation of EMT

Gang Zhang, Guangye Zhang
Pages: 3944-3951
Published online on: 19 February 2019

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Article

Characteristics of temperature changes in photothermal therapy induced by combined application of indocyanine green and laser

Shan Long, Yuanyuan Xu, Feifan Zhou, Bo Wang, Yunning Yang, Yan Fu, Nan Du, Xiaosong Li
Pages: 3952-3959
Published online on: 20 February 2019

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Article

Association of an miR‑502‑binding site polymorphism in the 3'‑untranslated region of SET8 with colorectal cancer

Shuang Liu, Hailing Dong, Jianhua Wu, Cuiju Wang
Pages: 3960-3964
Published online on: 07 February 2019

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Article

MicroRNA‑193b acts as a tumor suppressor gene in human esophageal squamous cell carcinoma via target regulation of KRAS

Min Kang, Yan Li, Shengtao Zhu, Shutian Zhang, Shuilong Guo, Peng Li
Pages: 3965-3973
Published online on: 13 February 2019

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Article

Expression of integrin α‑6 is associated with multi drug resistance and prognosis in ovarian cancer

Luwei Wei, Fuqiang Yin, Changxian Chen, Li Li
Pages: 3974-3980
Published online on: 20 February 2019

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Article

Inhibition of tumor growth and angiogenesis of tamoxifen‑resistant breast cancer cells by ruxolitinib, a selective JAK2 inhibitor

Ji Won Kim, Jaya Gautam, Ji Eun Kim, Jung‑Ae Kim, Keon Wook Kang
Pages: 3981-3989
Published online on: 20 February 2019

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Article

Application of Micro‑Tech stents in malignant carinal stenosis

Jin‑Mu Niu, Jie Zhang, Xiao‑Jian Qiu, Juan Wang, Ying‑Hua Pei, Yu‑Ling Wang, Ting Wang
Pages: 3990-3996
Published online on: 19 February 2019

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Article

Surgical lung biopsy in onco‑hematological patients with diffuse pulmonary infiltrates and mechanical ventilation in the ICU

Eduardo Mantovani Cardoso, Alexandre Galvão Bueno, Daniel Augusto Pavan, Ademar Dantas Cunha, Raysa Cristina Schmidt, Péricles A.D. Duarte
Pages: 3997-4003
Published online on: 21 February 2019

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Article

Prognostic impact of tumor‑infiltrating CD276/Foxp3‑positive lymphocytes and associated circulating cytokines in patients undergoing radical nephrectomy for localized renal cell carcinoma

Kota Iida, Makito Miyake, Kenta Onishi, Shunta Hori, Yosuke Morizawa, Daisuke Gotoh, Yoshitaka Itami, Sayuri Onishi, Yasushi Nakai, Satoshi Anai, Nobumichi Tanaka, Kiyohide Fujimoto
Pages: 4004-4010
Published online on: 20 February 2019

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Case Report

Metastatic renal cell carcinoma regains sensitivity to tyrosine kinase inhibitor after nivolumab treatment: A case report

Takeshi Azuma, Tohru Sugihara, Sachi Honda, Uran Yoshizaki, Fusako Niimi, Ibuki Tsuru, Haruki Kume
Pages: 4011-4015
Published online on: 08 February 2019

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Article

NOTCH1, SF3B1, MDM2 and MYD88 mutations in patients with chronic lymphocytic leukemia

Yosra Maleki, Zahra Alahbakhshi, Zahra Heidari, Mohammad‑Taher Moradi, Ziba Rahimi, Kheirolah Yari, Zohreh Rahimi, Mozafar Aznab, Meisam Ahmadi‑Khajevand, Fariborz Bahremand
Pages: 4016-4023
Published online on: 19 February 2019

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Article

Enhanced targeting of prostate cancer‑initiating cells by salinomycin‑encapsulated lipid‑PLGA nanoparticles linked with CD44 antibodies

Jun Wei, Jin Sun, Yu Liu
Pages: 4024-4033
Published online on: 19 February 2019

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Article

Hypoxia‑inducible factor-1 signaling pathway influences the sensitivity of HCC827 cells to gefitinib

Qian Jin, Jianying Zhou, Xianrong Xu, Feihua Huang, Weihua Xu
Pages: 4034-4043
Published online on: 07 February 2019

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Retraction Open Access

[Retracted] Identification of circulating tumor cells with EML4‑ALK translocation using fluorescence in situ hybridization in advanced ALK‑positive patients with lung cancer

Young Hun Kim, Eunjoo Hwang, Hye Seon Lee, Ji‑Hyun Uh, Myoung Shin Kim, Byung Hee Jeon
Pages: 4044-4044
Published online on: 12 February 2019

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Journal Cover
November-2026 Volume 32 Issue 5

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Ivonescimab combined with radiotherapy in the treatment of advanced lung adenocarcinoma with high expression of PD‑L1: A case report

Qi Zhou, Bo Yang, Hongyi Cai, Jun Jiang, Rong Chen
Article Number: 538
Published online on: 02 October 2026

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Article Open Access

Association between antidepressant exposure and prognosis in breast cancer: A systematic review and meta‑analysis

Qisong Chen, Yihan Shen, Xiaoming Zhang, Ting Jiang, Shiyan Zhang, Xinyan Yu, Feng Hong
Article Number: 537
Published online on: 02 October 2026

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Review Open Access

Brain‑derived neurotrophic factor in solid tumor angiogenesis and neurovascular‑immune interactions (Review)

Guoqing Zhu, Dianliang Zhang, Hao Wang, Sen Yan, Mingchao Ni, Shangkun Ning, Chong Wang, Mei Liu, Jibing Liu
Article Number: 536
Published online on: 01 October 2026

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Article Open Access

hnRNPC promotes oral squamous cell carcinoma progression via N6‑methyladenosine‑dependent stabilization of BCAT1 to enhance branched‑chain amino acid metabolism

Zhixin Zhang, Xin Gao, Ting Han, Fei Chai, Menghui Gao, Yulin An
Article Number: 535
Published online on: 01 October 2026

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Expression of Concern Open Access

[Expression of Concern] Reduced migration of Ishikawa cells associated with downregulation of aquaporin‑5

Xiu Xiu Jiang, Kai Hong Xu, Jun Yan Ma, Yong Hong Tian, Xiao Yan Guo, Jun Lin, Rui Jin Wu
Article Number: 534
Published online on: 30 September 2026

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Case Report Open Access

A thoracic SMARCA4‑deficient undifferentiated tumor: A case report

Xiaocheng Wang, Miao Chen, Mingzhe Wang, Chengjun Ban, Lishan Zhang, Heng Zou, Hongwu Wang, Bing Yang
Article Number: 533
Published online on: 29 September 2026

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Case Report Open Access

Stage IIIB pulmonary sarcomatoid carcinoma treated with spatially fractionated radiotherapy combined with antiangiogenic therapy and sequential chemo‑immunotherapy: A case report

Zijian Qiu, Feng Xuan, Xi Mao, Peipei Yang, Xiaoping Zhu
Article Number: 532
Published online on: 29 September 2026

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Article Open Access

Single‑cell transcriptomics identifies PRDX1 and GPX4 as potential ferroptosis regulators and tumor microenvironment‑­related molecules in hepatocellular carcinoma

Zhou Zhang, Hui Chen, Chen Qian, Ningning Yang, Zijing Liu, Ruirui Yang
Article Number: 531
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] Interferon‑α suppresses invasion and enhances cisplatin‑mediated apoptosis and autophagy in human osteosarcoma cells

Jun Zhao, Mingli Wang, Zeng Li, Jingxian Chen, Zongshen Yin, Jun Chang, Dongmei Gao, Shiping Wang
Article Number: 530
Published online on: 28 September 2026

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Article Open Access

KRT14 activated by transcription factor E2F1 promotes bladder cancer progression

Xingheng Chen, Sinan Liu, Xiaosong Zhang, Xiang Chen, Chenlu Wang
Article Number: 529
Published online on: 24 September 2026

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Review Open Access

Research progress of pancreatic cancer based on ferroptosis‑cuproptosis interaction (Review)

Wenqing Liu, Minglu Ding, Ruijiao Ji, Zhenmin Qiao, Ran Liu, Peijian Chen, Lantao Liu
Article Number: 528
Published online on: 24 September 2026

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Correction Open Access

[Corrigendum] Decreased expression of CD63 tetraspanin protein predicts elevated malignant potential in human esophageal cancer

Xiaojing Lai, Qing Gu, Xia Zhou, Wei Feng, Xiao Lin, Yan He, Jinming Cao, Pengfei Liu, Huojun Zhang, Xiao Zheng
Article Number: 527
Published online on: 24 September 2026

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Case Report Open Access

Therapy‑related acute myeloid leukemia with a rare complex karyotype following first‑line therapy for small cell lung cancer: A case report

Lin Luo, Sha Yu
Article Number: 526
Published online on: 23 September 2026

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Article Open Access

Netupitant‑palonosetron combined with dexamethasone for preventing chemotherapy‑induced nausea and vomiting in high‑risk patients with colorectal cancer receiving moderately emetogenic chemotherapy: A retrospective study

Jiwen Fan, Wenjuan Lai, Boran Cheng, Meijing Chen, Jing Gao, Shubin Wang, Gangling Tong
Article Number: 525
Published online on: 23 September 2026

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Correction Open Access

[Corrigendum] Upregulation of H19 promotes invasion and induces epithelial‑to‑mesenchymal transition in esophageal cancer

Cheng Huang, Lihua Cao, Limin Qiu, Xiaoli Dai, Linwei Ma, Yingting Zhou, Huifen Li, Min Gao, Weiyong Li, Qing Zhang, Koulan Han, Hongzhen Lv
Article Number: 524
Published online on: 23 September 2026

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Article Open Access

Pan‑cancer prognostic value of TGFBR1: Bioinformatics and experimental validation with a focus on gastric cancer

Xia Zhao, Lufan Shen, Zhiyuan Gong, Mengwen Lv, Yan Zhang, Bingxi Tang, Xinli Li
Article Number: 523
Published online on: 21 September 2026

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Article Open Access

MAD2L1 overexpression promotes breast cancer progression and confers resistance to paclitaxel via proteasomal stabilization

Shih-Ho Wang, Cheng-Hsi Yeh, Chia-Wei Wu, Chia-Yi Hsu, Eing-Mei Tsai, Chao-Ming Hung, Ming-Wei Lin, Tsung-Hua Hsieh
Article Number: 522
Published online on: 21 September 2026

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Article Open Access

Efficacy of circulating tumour DNA in guiding postoperative adjuvant chemotherapy for resectable colorectal cancer: A meta‑analysis based on cohort studies

Jiale Ruan, Wen Shi, Wenwen Shi, Xinyan Zhang, Yixia Chen, Xiaoling Feng, Jian Song
Article Number: 521
Published online on: 21 September 2026

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Article Open Access

Clinicopathological role of microRNA‑205, microRNA‑223 and microRNA‑590 in vulvar cancer

Edyta Leśniak, Emilia Stec-Martyna, Bartłomiej Tomasik, Hanna Romanowicz, Oliwia Maciejewska, Jan Bieńkiewicz, Andrzej Malinowski, Miłosz Wilczyński
Article Number: 520
Published online on: 21 September 2026

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Retraction Open Access

[Retracted] Regulatory effect of microRNA‑223‑3p on breast cancer cell processes via the Hippo/Yap signaling pathway

Tonghua Du, Dan Wang, Xiaoyu Wan, Jingwei Xu, Qi Xiao, Bin Liu
Article Number: 519
Published online on: 21 September 2026

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Article Open Access

Decitabine induces cell differentiation and growth inhibition accompanied by upregulation of microRNA‑143 and MS4A3 in the myelodysplastic syndromes‑derived leukemic cell line MDS‑L

Rie Nishi, Naoko Hosono, Kaoru Thoyama, Takahiro Yamauchi
Article Number: 518
Published online on: 18 September 2026

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Case Report Open Access

Malignant mesothelioma of the tunica vaginalis testis: A case report

Zhenjiang Liu, Aiyun Han, Shen Li, Jin Zhang, Yuanshan Guo, Chao Sun
Article Number: 517
Published online on: 18 September 2026

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Article Open Access

Methyltransferase‑like 7B promotes M2‑like macrophage polarization in lung adenocarcinoma via upregulating human epidermal growth factor receptor 3 expression and secretion

Sixiao He, Huibin Song, Jie Wu, Jinquan Xia, Ni Liu, Jia Cao, Zixuan Zhang, Xiaolin Cui, Chang Zou
Article Number: 516
Published online on: 18 September 2026

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Article Open Access

Exosomal miR‑145‑5p inhibits papillary thyroid cancer by targeting TPM3 and inactivating the PI3K‑Akt pathway

Yunfeng Weng, Xianjiao Cao, Wenyan Song, Qingqing He
Article Number: 515
Published online on: 17 September 2026

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Article Open Access

Identification of cancer‑associated fibroblast biomarkers in cutaneous squamous cell carcinoma

Yuanyuan Deng, Jue Qi, Yu Tang, Yueting Cun, Qian He, Li He
Article Number: 514
Published online on: 17 September 2026

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Article Open Access

Focal adhesion kinase inhibitor defactinib enhances olaparib‑induced suppression of BRCA‑proficient breast cancer cell proliferation

Hisako Ono, Keiko Taniguchi, Shusuke Yasuda, Mamiko Sukeno, Tomoya Matsui, Yasuto Naoi, Mano Horinaka, Toshiyuki Sakai
Article Number: 513
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

Geum-Hwa Lee, Do-Sung Kim, Myung Ja Chung, Soo-Wan Chae, Hyung-Ryong Kim, Han-Jung Chae
Article Number: 512
Published online on: 16 September 2026

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Review Open Access

Role of tumor necrosis factor receptor superfamily member 19 in cancer: Diverse functions and therapeutic potential (Review)

Manyu Xu, Zhaoyang Liu, Jingyu Zhang, Hanyun Xu, Yufei Xu, Yue Zhang, Qiong-Ying Hu, Tao Zhang
Article Number: 511
Published online on: 15 September 2026

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Article Open Access

Initiation of immune checkpoint inhibitor therapy in winter is associated with improved overall survival in patients with advanced non‑small cell lung cancer

Zhangxuan Chen, Jingsi Chen, Yang Yao, Xinjing Li, Ranpu Wu, Bingxue Wang, Jiajie Sun, Hongbing Liu
Article Number: 510
Published online on: 15 September 2026

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Article Open Access

Optimal timing of stereotactic radiosurgery with first‑line osimertinib in EGFR‑mutant non‑small cell lung cancer brain metastases: Immediate, early‑consolidation and salvage strategies

Xiaona Zhuang, Xiaoxiao Lu, Junjun Miao, Guangying Hou, Xiangkun Yuan
Article Number: 509
Published online on: 15 September 2026

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Article Open Access

Integrated analysis identified MARK4 as a prognostic and immunomodulatory biomarker in oral squamous cell carcinoma

Xinyue Zhang, Xiaoxue Shen, Sujun Hu, Rui Yao
Article Number: 508
Published online on: 15 September 2026

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Case Report Open Access

Combination of vinorelbine capsules and the small molecule anti‑angiogenic drug apatinib for first‑line treatment of advanced triple‑negative breast cancer with schizophrenia after failure of anthracycline and taxane therapy: A case report

Xue Bai, Liping Chen, Xuelian Chen, Dongcun Wang, Wenyan Kang, Lin Song, Meidi Liu, Caiwen Du
Article Number: 507
Published online on: 15 September 2026

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Review Open Access

Basis and prospects of radiotherapy combined with high‑intensity focused ultrasound ablation (Review)

Lingli Fan, Xiyue Yang, Jie Li, Yao Liao, Yuxi Bai, Xin Mao, Li Yuan, Feng Gao, Gang Feng, Qiuling Shi, Xiaobo Du
Article Number: 506
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] Remodeling of energy metabolism by a ketone body and medium‑chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells

Yui Kadochi, Shiori Mori, Rina Fujiwara-Tani, Yi Luo, Yukiko Nishiguchi, Shingo Kishi, Kiyomu Fujii, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 505
Published online on: 14 September 2026

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Article Open Access

Melatonin exerts an in vitro anti‑glioblastoma effect through SIRT1‑mediated HMGB1 deacetylation and inhibition of the TLR4/NF‑κB pathway

Beitian Shi, Yu Wang, Chao Zhang, Shiqiang Hou, Ning Lin, Lanlan Zhang
Article Number: 504
Published online on: 14 September 2026

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Case Report Open Access

Concurrent EGFR exon 19 deletion‑insertion and germline BRCA1 alteration in KRAS‑wild‑type pancreatic ductal adenocarcinoma: A case report and review of therapeutic implications

Sheng Yu Wei, Wei Yu, Qiao Huang
Article Number: 503
Published online on: 14 September 2026

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Review Open Access

Effect of extracellular vesicles on malignant tumours: Mechanisms and clinical findings (Review)

Ruiyi Shen, Qihong Lan, Yuan Lu, Ke Wen, Zhenzhen Wei, Qian Liu
Article Number: 502
Published online on: 11 September 2026

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Article

Circulating PCSK9: A new frontier in cancer risk stratification for obese diabetics

Lien-Cheng Tsao, Chen-Ling Kuo, Yu-Shan Cheng, Ching-Shan Huang, Chin-San Liu, Shih-Li Su
Article Number: 501
Published online on: 11 September 2026

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Review Open Access

Multifaceted roles of chemokines in gastric cancer: From tumor microenvironment modulation to therapeutic targeting (Review)

Zhanping Li, Zhongdang Xiao
Article Number: 500
Published online on: 11 September 2026

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Article

Identification and assessment of FN1, MET, KRT19 and CLDN1 as key dysregulated genes in papillary thyroid cancer through transcriptomic profiling and expression analysis

Anette Roxana Gastelum-Quiroz, Noemí García-Magallanes, Andrea Ross‑Orozco, Marco Alvarez‑Arrazola, Fred Luque‑Ortega, Karla Lizbeth Morales‑Hernández, Dora Cedano‑Prieto, Vanessa G. Félix, Eliakym Arámbula‑Meraz
Article Number: 499
Published online on: 11 September 2026

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Correction Open Access

[Corrigendum] Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 498
Published online on: 10 September 2026

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Article

Integrated bioinformatics and feature selection-based discovery of ADP-ribosylation-associated biomarkers in non-small cell lung cancer

Jie He, Qingtao Zhao, Hongzhen Zhao, Hua Zhang, Zhonghui Hu, Lingxin Kong, Zengming Wang, Jianghong Yan, Shuo Yang, Shicheng Liu
Article Number: 497
Published online on: 08 September 2026

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Review Open Access

Mechanism‑guided radiosensitization strategies for nasopharyngeal carcinoma: Current evidence and translational perspectives (Review)

Wei Deng, Ziyun Li, Zhenhua Zhu
Article Number: 496
Published online on: 08 September 2026

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Retraction Open Access

[Retracted] Characterization of sonic hedgehog inhibition in gastric carcinoma cells

Ruxue Bai, Hongchuan Zhao, Xiang Zhang, Shiyu Du
Article Number: 495
Published online on: 08 September 2026

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Article Open Access

KLF2 as a prognostic and potential therapeutic target associated with ferroptosis in serous ovarian cancer: An integrative bioinformatics and clinical validation study

Yuanyi Wang, Juan Yu, Wu Huang, Yuan Yuan, Xiangbo Lan, Youli Jian, Xiao Li, Simei Wang, Xiao Huang, Ge Xu, Xing Wei
Article Number: 494
Published online on: 07 September 2026

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Case Report Open Access

Pathological transformation of rectal adenocarcinoma to choriocarcinoma in a male patient: A case report and review of the literature

Yefang Lao, Xikai Zhang, Zhongzhong Peng, Xiao Zhou, Xianyuan Miao, Qiongqiong Wang, Sijia Ren, Kaifeng Wang, Hongmin Lu
Article Number: 493
Published online on: 07 September 2026

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Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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December-2026 Volume 32 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Correction Open Access

[Corrigendum] Emodin induces apoptosis of human breast cancer cells by modulating the expression of apoptosis‑related genes

Cong Zu, Mingdi Zhang, Hui Xue, Xiaopeng Cai, Lei Zhao, Anning He, Guangyuan Qin, Chunshu Yang, Xinyu Zheng
Article Number: 539
Published online on: 02 October 2026

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