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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2019 Volume 17 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

F‑box/WD‑40 repeat‑containing protein 7: A potential target in the progression and treatment of gastrointestinal malignancy (Review)

Yizhi Wang, Yang An, Yi Ma, Junchao Guo
Pages: 3625-3634
Published online on: 13 February 2019

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Review

A research update on the anticancer effects of bufalin and its derivatives (Review)

Yu‑Long Lan, Jia‑Cheng Lou, Xue‑Wen Jiang, Xun Wang, Jin‑Shan Xing, Shao Li, Bo Zhang
Pages: 3635-3640
Published online on: 21 February 2019

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Article Open Access

4‑Dimensional computed tomography analysis of clinical target volume displacement in adjuvant radiation of patients with gastric cancer and its implication on radiotherapy

Jin Peng, Jun Gong, Xiaoyong Wang, Jingjing Mou, Hui Xu, Jing Dai, Fuxiang Zhou, Yunfeng Zhou
Pages: 3641-3648
Published online on: 13 February 2019

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Article Open Access

Stratification of patients with colorectal cancer without the recorded family history

Ivana Kašubová, Michal Kalman, Karin Jašek, Tatiana Burjanivová, Bibiana Malicherová, Andrea Vaňochová, Sandra Meršaková, Zora Lasabová, Lukáš Plank
Pages: 3649-3656
Published online on: 06 February 2019

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Article Open Access

The oncogenic role of Wnt10a in colorectal cancer through activation of canonical Wnt/β‑catenin signaling

Jinlong Li, Zhaoli Zhang, Lixue Wang, Yongchen Zhang
Pages: 3657-3664
Published online on: 13 February 2019

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Article Open Access

Curative effect of endostar combined with oxaliplatin in the treatment of primary hepatic carcinoma and its influence on immune cells

Changjiang Lei, Defa Ren, Meixia Fu, Chuantao Sun, Hong Ren, Qingyun Pan, Yuan Li
Pages: 3665-3670
Published online on: 06 February 2019

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Article Open Access

Self‑made thoracic needled suspending device with a snare: An excellent aid for uniportal video‑assisted thoracic lobectomy and segmentectomy for lung cancer Corrigendum in /10.3892/ol.2020.11409

Shanlei Wang, Chuizheng Meng, Zhongmin Jiang, Diego Gonzalez-Rivas, Junfen Ruan, Wei Xu, Chuanping Liu, Lei Zhang, Guogang Gao, Ge Yu, Hezhi Teng, Jin Ju
Pages: 3671-3676
Published online on: 12 February 2019

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Article Open Access

In silico detection of potential prognostic circRNAs through a re‑annotation strategy in ovarian cancer

Qiuyan Guo, Yanan He, Liyuan Sun, Congcong Kong, Yan Cheng, Guangmei Zhang
Pages: 3677-3686
Published online on: 06 February 2019

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Article Open Access

Expression and prognostic significance of Fanconi anemia group D2 protein and breast cancer type 1 susceptibility protein in familial and sporadic breast cancer

Liang Feng, Feng Jin
Pages: 3687-3700
Published online on: 18 February 2019

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Article Open Access

Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines

Yu Li, Xin Chen, Yong Cui, Qun Wei, Suiyun Chen, Xiaofang Wang
Pages: 3701-3708
Published online on: 21 February 2019

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Article Open Access

P21 activated kinase 2 promotes pancreatic cancer growth and metastasis Retraction in /10.3892/ol.2023.13949

Guo‑Wang Yao, Jing‑Rui Bai, Da‑Peng Zhang
Pages: 3709-3718
Published online on: 14 February 2019

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Article Open Access

Inhibition of the PI3K/AKT signaling pathway sensitizes diffuse large B‑cell lymphoma cells to treatment with proteasome inhibitors via suppression of BAG3

Ting Yuan, Feng Zhang, Xiangxiang Zhou, Ying Li, Ya Zhang, Yangyang Xu, Xin Wang
Pages: 3719-3726
Published online on: 08 February 2019

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Article Open Access

Regulatory effect of Act1 on the BAFF pathway in B‑cell malignancy

Xiao‑Jun Ge, Yong‑Lun Wang, Yang Ping Wu, Zhong‑Xin Feng, Lan Liu, Mei Yong Li, Jun‑Yao Jiang
Pages: 3727-3734
Published online on: 18 February 2019

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Article Open Access

Silencing of EPHB2 promotes the epithelial‑mesenchymal transition of skin squamous cell carcinoma‑derived A431 cells

Yoshinori Inagaki, Tomohiko Tokunaga, Mitsuru Yanai, Dan Wu, Jiyi Huang, Hiroki Nagase, Noboru Fukuda, Toshinori Ozaki, Masayoshi Soma, Kyoko Fujiwara
Pages: 3735-3742
Published online on: 06 February 2019

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Article Open Access

Analysis of the promoter region of the human miR‑32 gene in colorectal cancer

Weiyun Wu, Wenkai Tan, Shicai Ye, Yu Zhou, Juanhua Quan
Pages: 3743-3750
Published online on: 14 February 2019

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Article Open Access

Identification of key pathways and candidate genes in pancreatic ductal adenocarcinoma using bioinformatics analysis

Yiping He, Yan Liu, Jianping Gong, Changan Liu, Hua Zhang, Hao Wu
Pages: 3751-3764
Published online on: 14 February 2019

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Article Open Access

Differential microRNA expression profiles determined by next‑generation sequencing in three fulvestrant‑resistant human breast cancer cell lines

Juan Guo, Keli He, Hui Zeng, Yu Shi, Peng Ye, Qian Zhou, Zhongya Pan, Xinghua Long
Pages: 3765-3776
Published online on: 21 February 2019

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Article Open Access

Application value of nursing intervention combined with early nutritional support in preventive stoma reversion of low rectal cancer

Xinmei Ye, Dandan He, Jie Zhao, Yuqing Lei, Qiuqiong Yao, Hui Wang
Pages: 3777-3782
Published online on: 19 February 2019

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Article Open Access

Resveratrol induces p53 in colorectal cancer through SET7/9

Zhonglun Liu, Xiaohong Wu, Jingjing Lv, Hui Sun, Feiqin Zhou
Pages: 3783-3789
Published online on: 13 February 2019

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Article Open Access

miR‑944 inhibits lung adenocarcinoma tumorigenesis by targeting STAT1 interaction

Jing Chun An, Han‑Bing Shi, Wen‑Bo Hao, Kun Zhu, Bo Ma
Pages: 3790-3798
Published online on: 18 February 2019

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Article Open Access

Isolation of circulating tumor cells and detection of EGFR mutations in patients with non‑small‑cell lung cancer

Qi Zhang, Jingying Nong, Jinghui Wang, Zhuohong Yan, Ling Yi, Xin Gao, Zhidong Liu, Hongtao Zhang, Shucai Zhang
Pages: 3799-3807
Published online on: 05 February 2019

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Article Open Access

Determination of the complexity and diversity of the TCR β‑chain CDR3 repertoire in bladder cancer using high‑throughput sequencing

Jingsheng Ma, Guoping Sun, Peng Zhu, Song Liu, Minglin Ou, Zhiqiang Chen, Chang Zou, Frank Leing Chan, Yong Dai, Weiguo Sui
Pages: 3808-3816
Published online on: 05 February 2019

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Article Open Access

Isolation of circulating tumor cells in patients undergoing surgery for esophageal cancer and a specific confirmation method. Corrigendum in /10.3892/ol.2019.10878

Yunpeng Zhao, Shukang Zhao, Yingjie Chen, Xiaopeng Dong, Chuanliang Peng, Qifeng Sun, Lei Shan, Zhendan Wang, Xiaogang Zhao
Pages: 3817-3825
Published online on: 06 February 2019

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Article Open Access

p53 overexpression is a prognosticator of poor outcome in esophageal cancer

Nathaniel Melling, Sonja Norrenbrock, Martina Kluth, Ronald Simon, Claudia Hube‑Magg, Stefan Steurer, Andrea Hinsch, Eike Burandt, Frank Jacobsen, Waldemar Wilczak, Alexander Quaas, Maximillian Bockhorn, Katharina Grupp, Michael Tachezy, Jakob Izbicki, Guido Sauter, Florian Gebauer
Pages: 3826-3834
Published online on: 06 February 2019

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Article Open Access

miR‑140‑3p inhibits breast cancer proliferation and migration by directly regulating the expression of tripartite motif 28

Yu Zhou, Bo Wang, Yu Wang, Gaohui Chen, Qixin Lian, Haidong Wang
Pages: 3835-3841
Published online on: 13 February 2019

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Article Open Access

Luteolin inhibits cell cycle progression and induces apoptosis of breast cancer cells through downregulation of human telomerase reverse transcriptase

Liming Huang, Ketao Jin, Huanrong Lan
Pages: 3842-3850
Published online on: 19 February 2019

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Article Open Access

Expression patterns and the prognostic value of the SMYD family members in human breast carcinoma using integrative bioinformatics analysis

Jianping Song, Yanfeng Liu, Qian Chen, Jinhuan Yang, Zhengchen Jiang, Hao Zhang, Zhaojian Liu, Bin Jin
Pages: 3851-3861
Published online on: 19 February 2019

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Case Report Open Access

Small bowel perforation with multiple intestinal metastases from lung carcinoma: A case report

Evangelos P. Misiakos, Alina‑Roxani Gouloumi, Dimitrios Schizas, Vasileia Damaskou, Dimitrios Tsapralis, Frederick‑Anthony Farrugia, Nikolaos Machairas, Dimitrios Papaconstantinou, Ariadni Tzaneti, Anastasios Machairas
Pages: 3862-3866
Published online on: 12 February 2019

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Article Open Access

Measurement of morphological parameters of giant cell tumor of bone in the knee

Lin Guo, Peng Jia, Yong‑Cheng Hu, Man Sun, Zhi Wang, Xue‑Ning Zhang, Jun Miao
Pages: 3867-3873
Published online on: 21 February 2019

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Article Open Access

The long non‑coding RNA LINC00460 predicts the prognosis and promotes the proliferation and migration of cells in bladder urothelial carcinoma

Lijie Wen, Xiling Zhang, Jing Bian, Li Han, Haibo Huang, Miao He, Minjie Wei, Ping Wang
Pages: 3874-3880
Published online on: 07 February 2019

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Article Open Access

Gene expression profile analysis of ENO1 knockdown in gastric cancer cell line MGC‑803

Zhigang Huang, Bode Lin, Haiyan Pan, Jinlin Du, Rongwei He, Shizhuo Zhang, Ping Ouyang
Pages: 3881-3889
Published online on: 19 February 2019

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Article Open Access

Tumor response to irinotecan is associated with CYP3A5 expression in colorectal cancer

Emanuel Buck, Martin Sprick, Matthias M. Gaida, Carsten Grüllich, Tim Frederik Weber, Esther Herpel, Thomas Bruckner, Ronald Koschny
Pages: 3890-3898
Published online on: 14 February 2019

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Case Report Open Access

Primary malignant gastrointestinal neuroectodermal tumor occurring in the ileum with intra‑abdominal granulomatous nodules: A case report and review of the literature

Gao‑Xiang Huang, Qiu‑Yue Chen, Ling‑Ling Zhong, Hao Chen, Hai‑Peng Zhang, Xiao‑Fen Liu, Fang Tang
Pages: 3899-3909
Published online on: 21 February 2019

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Article Open Access

Expression of total and phospho 4EBP1 in metastatic and non‑metastatic renal cell carcinoma

Sei Naito, Osamu Ichiyanagi, Hiromi Ito, Takanobu Kabasawa, Hidenori Kanno, Takafumi Narisawa, Hiroki Fukuhara, Mayu Yagi, Yuta Kurota, Atsushi Yamagishi, Toshihiko Sakurai, Hayato Nishida, Hisashi Kawazoe, Takuya Yamanobe, Tomoyuki Kato, Peter Makhov, Vladimir M. Kolenko, Mitsunori Yamakawa, Norihiko Tsuchiya
Pages: 3910-3918
Published online on: 12 February 2019

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Article Open Access

Clinical value of miRNA‑122 in the diagnosis and prognosis of various types of cancer

Meiyu Dai, Limin Li, Xue Qin
Pages: 3919-3929
Published online on: 07 February 2019

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Article

Phase I study of preoperative chemoradiotherapy with sequential oxaliplatin and irinotecan with S‑1 for locally advanced rectal cancer

Hiroyuki Fujikawa, Yuji Toiyama, Yasuhiro Inoue, Yusuke Omura, Shozo Ide, Takahito Kitajima, Hiromi Yasuda, Yoshinaga Okugawa, Yoshiki Okita, Shigeyuki Yoshiyama, Junichiro Hiro, Minako Kobayashi, Masaki Ohi, Toshimitsu Araki, Masato Kusunoki
Pages: 3930-3936
Published online on: 08 February 2019

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Article

Immunohistochemical expression and clinicopathological assessment of the cancer testis antigens NY‑ESO‑1 and MAGE‑A4 in high‑grade soft‑tissue sarcoma

Takuya Kakimoto, Akihiko Matsumine, Shinichi Kageyama, Kunihiro Asanuma, Takao Matsubara, Tomoki Nakamura, Takahiro Iino, Hiroaki Ikeda, Hiroshi Shiku, Akihiro Sudo
Pages: 3937-3943
Published online on: 14 February 2019

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Article

Upregulation of FoxP4 in HCC promotes migration and invasion through regulation of EMT

Gang Zhang, Guangye Zhang
Pages: 3944-3951
Published online on: 19 February 2019

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Article

Characteristics of temperature changes in photothermal therapy induced by combined application of indocyanine green and laser

Shan Long, Yuanyuan Xu, Feifan Zhou, Bo Wang, Yunning Yang, Yan Fu, Nan Du, Xiaosong Li
Pages: 3952-3959
Published online on: 20 February 2019

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Article

Association of an miR‑502‑binding site polymorphism in the 3'‑untranslated region of SET8 with colorectal cancer

Shuang Liu, Hailing Dong, Jianhua Wu, Cuiju Wang
Pages: 3960-3964
Published online on: 07 February 2019

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Article

MicroRNA‑193b acts as a tumor suppressor gene in human esophageal squamous cell carcinoma via target regulation of KRAS

Min Kang, Yan Li, Shengtao Zhu, Shutian Zhang, Shuilong Guo, Peng Li
Pages: 3965-3973
Published online on: 13 February 2019

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Article

Expression of integrin α‑6 is associated with multi drug resistance and prognosis in ovarian cancer

Luwei Wei, Fuqiang Yin, Changxian Chen, Li Li
Pages: 3974-3980
Published online on: 20 February 2019

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Article

Inhibition of tumor growth and angiogenesis of tamoxifen‑resistant breast cancer cells by ruxolitinib, a selective JAK2 inhibitor

Ji Won Kim, Jaya Gautam, Ji Eun Kim, Jung‑Ae Kim, Keon Wook Kang
Pages: 3981-3989
Published online on: 20 February 2019

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Article

Application of Micro‑Tech stents in malignant carinal stenosis

Jin‑Mu Niu, Jie Zhang, Xiao‑Jian Qiu, Juan Wang, Ying‑Hua Pei, Yu‑Ling Wang, Ting Wang
Pages: 3990-3996
Published online on: 19 February 2019

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Article

Surgical lung biopsy in onco‑hematological patients with diffuse pulmonary infiltrates and mechanical ventilation in the ICU

Eduardo Mantovani Cardoso, Alexandre Galvão Bueno, Daniel Augusto Pavan, Ademar Dantas Cunha, Raysa Cristina Schmidt, Péricles A.D. Duarte
Pages: 3997-4003
Published online on: 21 February 2019

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Article

Prognostic impact of tumor‑infiltrating CD276/Foxp3‑positive lymphocytes and associated circulating cytokines in patients undergoing radical nephrectomy for localized renal cell carcinoma

Kota Iida, Makito Miyake, Kenta Onishi, Shunta Hori, Yosuke Morizawa, Daisuke Gotoh, Yoshitaka Itami, Sayuri Onishi, Yasushi Nakai, Satoshi Anai, Nobumichi Tanaka, Kiyohide Fujimoto
Pages: 4004-4010
Published online on: 20 February 2019

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Case Report

Metastatic renal cell carcinoma regains sensitivity to tyrosine kinase inhibitor after nivolumab treatment: A case report

Takeshi Azuma, Tohru Sugihara, Sachi Honda, Uran Yoshizaki, Fusako Niimi, Ibuki Tsuru, Haruki Kume
Pages: 4011-4015
Published online on: 08 February 2019

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Article

NOTCH1, SF3B1, MDM2 and MYD88 mutations in patients with chronic lymphocytic leukemia

Yosra Maleki, Zahra Alahbakhshi, Zahra Heidari, Mohammad‑Taher Moradi, Ziba Rahimi, Kheirolah Yari, Zohreh Rahimi, Mozafar Aznab, Meisam Ahmadi‑Khajevand, Fariborz Bahremand
Pages: 4016-4023
Published online on: 19 February 2019

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Article

Enhanced targeting of prostate cancer‑initiating cells by salinomycin‑encapsulated lipid‑PLGA nanoparticles linked with CD44 antibodies

Jun Wei, Jin Sun, Yu Liu
Pages: 4024-4033
Published online on: 19 February 2019

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Article

Hypoxia‑inducible factor-1 signaling pathway influences the sensitivity of HCC827 cells to gefitinib

Qian Jin, Jianying Zhou, Xianrong Xu, Feihua Huang, Weihua Xu
Pages: 4034-4043
Published online on: 07 February 2019

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Retraction Open Access

[Retracted] Identification of circulating tumor cells with EML4‑ALK translocation using fluorescence in situ hybridization in advanced ALK‑positive patients with lung cancer

Young Hun Kim, Eunjoo Hwang, Hye Seon Lee, Ji‑Hyun Uh, Myoung Shin Kim, Byung Hee Jeon
Pages: 4044-4044
Published online on: 12 February 2019

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Journal Cover
May-2026 Volume 31 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

TBX20 regulates epithelial‑mesenchymal transition, maintains tumor stemness and immune factor expression, and promotes immune escape in lung cancer

Chuncai Xu, Peng Zhou, Yanting Zhang, Lili Li, Guowen Wang
Article Number: 207
Published online on: 30 March 2026

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Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
Article Number: 206
Published online on: 30 March 2026

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Article

Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
Published online on: 30 March 2026

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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
Article Number: 204
Published online on: 30 March 2026

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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
Article Number: 203
Published online on: 30 March 2026

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Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
Article Number: 202
Published online on: 30 March 2026

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Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
Article Number: 201
Published online on: 30 March 2026

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Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

Ruoxuan Li, Luping Pan, Fujuan Zeng, Jingyu Huang, Ziye Chen, Chengyi Liu, Zhimin Zeng
Article Number: 200
Published online on: 30 March 2026

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Article Open Access

Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
Article Number: 199
Published online on: 30 March 2026

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Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
Article Number: 198
Published online on: 27 March 2026

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Article Open Access

Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
Article Number: 197
Published online on: 26 March 2026

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Article Open Access

Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
Published online on: 26 March 2026

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Review Open Access

Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
Article Number: 195
Published online on: 26 March 2026

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Case Report Open Access

A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
Article Number: 194
Published online on: 26 March 2026

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Article Open Access

Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Review Open Access

Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Article Open Access

Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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Article Open Access

SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
Article Number: 190
Published online on: 24 March 2026

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Case Report Open Access

Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
Published online on: 24 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
Article Number: 188
Published online on: 23 March 2026

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Case Report Open Access

Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Article Open Access

Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
Article Number: 186
Published online on: 19 March 2026

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Article Open Access

Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
Article Number: 185
Published online on: 19 March 2026

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Review Open Access

Metabolic reprogramming‑a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review)

Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Article Open Access

Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 183
Published online on: 18 March 2026

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Article Open Access

Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
Published online on: 18 March 2026

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Article Open Access

Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
Article Number: 180
Published online on: 17 March 2026

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Correction Open Access

[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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Article

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
Article Number: 178
Published online on: 17 March 2026

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Case Report

Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Case Report

Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Review

Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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Retraction Open Access

[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Case Report Open Access

Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Article

Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Article Open Access

Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Article Open Access

Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Article Open Access

Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

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SCImago Journal Rank (SJR): 0.663

Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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