|
1
|
Feng B, Zhang K, Wang R and Chen L:
Non-small-cell lung cancer and miRNAS: Novel biomarkers and
promising tools for treatment. Clin Sci (Lond). 128:619–634. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2018. CA Cancer J Clin. 68:7–30. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
World Health Organization. 2002,
https://www.who.int/bulletin/archives/80(1)78.pdfJune
18–2018
|
|
4
|
Smith CB, Kelley AS and Meier DE: Evidence
for new standard of care in non-small cell lung cancer patients.
Semin Thorac Cardiovasc Surg. 22:193–194. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Stuschke M, Eberhardt W, Pöttgen C,
Stamatis G, Wilke H, Stüben G, Stöblen F, Wilhelm HH, Menker H,
Teschler H, et al: Prophylactic cranial irradiation in locally
advanced non-small-cell lung cancer after multimodality treatment:
Long-term follow-up and investigations of late neuropsychologic
effects. J Clin Oncol. 17:2700–2709. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Minguet J, Smith KH and Bramlage P:
Targeted therapies for treatment of non-small cell lung
cancer-recent advances and future perspectives. Int J Cancer.
138:2549–2561. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Xu JH, Yang HP, Zhou XD, Wang HJ, Liang G
and Tang CL: Role of Wnt inhibitory factor-1 in inhibition of
bisdemethoxycurcumin mediated epithelial-to-mesenchymal transition
in highly metastatic lung cancer 95D cells. Chin Med J (Engl).
128:1376–1383. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Wu T, Geng J, Guo W, Gao J and Zhu X:
Asiatic acid inhibits lung cancer cell growth in vitro and in vivo
by destroying mitochondria. Acta Pharm Sin B. 7:65–72. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Lu Y, Liu S, Wang Y, Wang D, Gao J and Zhu
L: Asiatic acid uncouples respiration in isolated mouse liver
mitochondria and induces HepG2 cells death. Eur J Pharmacol.
786:212–223. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Ren L, Cao QX, Zhai FR, Yang SQ and Zhang
HX: Asiatic acid exerts anticancer potential in human ovarian
cancer cells via suppression of PI3K/Akt/mTOR signalling. Pharm
Biol. 54:2377–2382. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Park BC, Paek SH, Lee YS, Kim SJ, Lee ES,
Choi HG, Yong CS and Kim JA: Inhibitory effects of asiatic acid on
7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol
13-acetate-induced tumor promotion in mice. Biol Pharm Bull.
30:176–179. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Tang XL, Yang XY, Jung HJ, Kim SY, Jung
SY, Choi DY, Park WC and Park H: Asiatic acid induces colon cancer
cell growth inhibition and apoptosis through mitochondrial death
cascade. Biol Pharm Bull. 32:1399–1405. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Yilmaz M and Christofori G: EMT, the
cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev.
28:15–33. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Ke Y, Zhao W, Xiong J and Cao R: miR-149
inhibits non-small-cell lung cancer cells EMT by targeting FOXM1.
Biochem Res Int. 2013:5067312013. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Roy BC, Kohno T, Iwakawa R, Moriguchi T,
Kiyono T, Morishita K, Sanchez-Cespedes M, Akiyama T and Yokota J:
Involvement of LKB1 in epithelial-mesenchymal transition (EMT) of
human lung cancer cells. Lung Cancer. 70:136–145. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Shen SJ, Zhang YH, Gu XX, Jiang SJ and Xu
LJ: Yangfei Kongliu formula, a compound Chinese herbal medicine,
combined with cisplatin, inhibits growth of lung cancer cells
through transforming growth factor-β1 signaling pathway. J Integr
Med. 15:242–251. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Al-Saad S, Al-Shibli K, Donnem T, Persson
M, Bremnes RM and Busund LT: The prognostic impact of NF-kappaB
p105, vimentin, E-cadherin and Par6 expression in epithelial and
stromal compartment in non-small-cell lung cancer. Br J Cancer.
99:1476–1483. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zhang HJ, Wang HY, Zhang HT, Su JM, Zhu J,
Wang HB, Zhou WY, Zhang H, Zhao MC, Zhang L and Chen XF:
Transforming growth factor-β1 promotes lung adenocarcinoma invasion
and metastasis by epithelial-to-mesenchymal transition. Mol Cell
Biochem. 355:309–314. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zang QQ, Lu Z, Ning G and Cheng H:
Ophiopogonin D inhibits cell proliferation, causes cell cycle
arrest at G2/M, and induces apoptosis in human breast carcinoma
MCF-7 cells. J Integr Med. 14:51–59. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Liu JJ, Liu JY, Chen J, Wu YX, Yan P, Ji
CD, Wang YX, Xiang DF, Zhang X, Zhang P, et al: Scinderin promotes
the invasion and metastasis of gastric cancer cells and predicts
the outcome of patients. Cancer Lett. 376:110–117. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Uygun K, Bilici A, Kaya S, Oven
Ustaalioglu BB, Yildiz R, Temiz S, Seker M, Aksu G, Cabuk D and
Gumus M: XELIRI plus bevacizumab compared with FOLFIRI plus
bevacizumab as first-line setting in patients with metastatic
colorectal cancer: Experiences at two-institutions. Asian Pac J
Cancer Prev. 14:2283–2288. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Beekman JM, Reischl J, Henderson D, Bauer
D, Ternes R, Peña C, Lathia C and Heubach JF: Recovery of
microarray-quality RNA from frozen EDTA blood samples. J Pharmacol
Toxicol Methods. 59:44–49. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Yang J and Weinberg RA:
Epithelial-mesenchymal transition: At the crossroads of development
and tumor metastasis. Dev Cell. 14:818–829. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Nagathihalli NS, Massion PP, Gonzalez AL,
Lu P and Datta PK: Smoking induces epithelial-to-mesenchymal
transition in Non-small cell lung cancer through HDAC-mediated
downregulation of E-cadherin. Mol Cancer Ther. 11:2362–2372. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Aref AR, Huang RYJ, Kang W, Jing SW,
Thiery JP and Kamm RD: Transitions between epithelial and
mesenchymal states in microfluidic platform. Acquisition of
malignant and stem cell traits. 2013.
|
|
27
|
Kiesslich T, Pichler M and Neureiter D:
Epigenetic control of epithelial-mesenchymal-transition in human
cancer. Mol Clin Oncol. 1:3–11. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Zhao R, Gong L, Li L, Guo L, Zhu D, Wu Z
and Zhou Q: nM23-H1 is a negative regulator of TGF-β1-dependent
induction of epithelial-mesenchymal transition. Exp Cell Res.
319:740–749. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Reinhold WC, Reimers MA, Lorenzi P, Ho J,
Shankavaram UT, Ziegler MS, Bussey KJ, Nishizuka S, Ikediobi O,
Pommier YG and Weinstein JN: Multifactorial regulation of
E-cadherin expression: An integrative study. Mol Cancer Ther.
9:1–16. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Cho KH, Yu SL, Cho DY, Chang GP and Hoi
YL: Breast cancer metastasis suppressor 1 (BRMS1) attenuates
TGF-β1-induced breast cancer cell aggressiveness through
downregulating HIF-1α expression. BMC Cancer. 15:8292015.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Toba-Ichihashi Y, Yamaoka T, Ohmori T and
Ohba M: Up-regulation of Syndecan-4 contributes to TGF-β1-induced
epithelial to mesenchymal transition in lung adenocarcinoma A549
cells. Biochem Biophys Rep. 5:1–7. 2015.PubMed/NCBI
|
|
32
|
Li Y, Zhu G, Zhai H, Jia J, Yang W, Li X
and Liu L: Simultaneous stimulation with tumor necrosis factor-α
and transforming growth factor-β1 induces epithelial-mesenchymal
transition in colon cancer cells via the NF-κB pathway. Oncol Lett.
15:6873–6880. 2018.PubMed/NCBI
|
|
33
|
Ding Y, Shen S, Lino AC, Curotto de
Lafaille MA and Lafaille JJ: Beta-catenin stabilization extends
regulatory T cell survival and induces anergy in nonregulatory T
cells. Nat Med. 14:162–169. 2008. View
Article : Google Scholar : PubMed/NCBI
|
|
34
|
Shakoori A, Ougolkov A, Yu ZW, Zhang B,
Modarressi MH, Billadeau DD, Mai M, Takahashi Y and Minamoto T:
Deregulated GSK3beta activity in colorectal cancer: Its association
with tumor cell survival and proliferation. Biochem Biophys Res
Commun. 334:1365–1373. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Singh A and Settleman J: EMT, cancer stem
cells and drug resistance: An emerging axis of evil in the war on
cancer. Oncogene. 29:4741–4751. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Lin XL, Liu M, Liu Y, Hu H, Pan Y, Zou W,
Fan X and Hu X: Transforming growth factor β1 promotes migration
and invasion in HepG2 cells: Epithelial-to-mesenchymal transition
via JAK/STAT3 signaling. Int J Mol Med. 41:129–136. 2018.PubMed/NCBI
|
|
37
|
Talmadge JE and Fidler IJ: AACR centennial
series: The biology of cancer metastasis: Historical perspective.
Cancer Res. 70:5649–5669. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Macdonald PR, Progias P, Ciani B, Patel S,
Mayer U, Steinmetz MO and Kammerer RA: Structure of the
extracellular domain of Tie receptor tyrosine kinases and
localization of the angiopoietin-binding epitope. J Biol Chem.
281:28408–28414. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Abuetabh Y, Persad S, Nagamori S, Huggins
J, Al-Bahrani R and Sergi C: Expression of E-cadherin and β-catenin
in two cholangiocarcinoma cell lines (OZ and HuCCT1) with different
degree of invasiveness of the primary tumor. Ann Clin Lab Sci.
41:217–223. 2011.PubMed/NCBI
|
|
40
|
Chunhacha P, Sriuranpong V and
Chanvorachote P: Epithelial-mesenchymal transition mediates anoikis
resistance and enhances invasion in pleural effusion-derived human
lung cancer cells. Oncol Lett. 5:1043–1047. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Zhang H, Liu J, Yue D, Gao L, Wang D,
Zhang H and Wang C: Clinical significance of E-cadherin, β-catenin,
vimentin and S100A4 expression in completely resected squamous cell
lung carcinoma. J Clin Pathol. 66:937–945. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Batlle E, Sancho E, Francí C, Domínguez D,
Monfar M, Baulida J and García De Herreros A: The transcription
factor snail is a repressor of E-cadherin gene expression in
epithelial tumour cells. Nat Cell Biol. 2:84–89. 2000. View Article : Google Scholar : PubMed/NCBI
|
