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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2019 Volume 17 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Editorial Open Access

[Editorial] The 2nd Conference of the Romanian Society of Immuno‑Dermatology, Bucharest, September 27-29, 2018

Monica Neagu, Daniel Boda
Pages: 4053-4054
Published online on: 27 February 2019

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Article Open Access

Dendritic cell distribution in mycosis fungoides vs. inflammatory dermatosis and other T-cell skin lymphoma

Mirela Cioplea, Costin Caruntu, Sabina Zurac, Alexandra Bastian, Liana Sticlaru, Alexandra Cioroianu, Daniel Boda, Gheorghita Jugulete, Luciana Nichita, Cristiana Popp
Pages: 4055-4059
Published online on: 01 March 2019

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Review Open Access

Angiogenesis in cutaneous T‑cell lymphoma ‑ proteomic approaches (Review)

Cristiana Tanase, Ionela Daniela Popescu, Ana‑Maria Enciu, Ancuta Augustina Gheorghisan‑Galateanu, Elena Codrici, Simona Mihai, Lucian Albulescu, Laura Necula, Radu Albulescu
Pages: 4060-4067
Published online on: 19 November 2018

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Review Open Access

Inflammation: A key process in skin tumorigenesis (Review)

Monica Neagu, Carolina Constantin, Constantin Caruntu, Carmen Dumitru, Mihaela Surcel, Sabina Zurac
Pages: 4068-4084
Published online on: 19 November 2018

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Review

Photodynamic therapy: A hot topic in dermato-oncology (Review)

Mircea Tampa, Maria-Isabela Sarbu, Clara Matei, Cristina-Iulia Mitran, Madalina-Irina Mitran, Constantin Caruntu, Carolina Constantin, Monica Neagu, Simona-Roxana Georgescu
Pages: 4085-4093
Published online on: 16 January 2019

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Case Report Open Access

Non-invasive imaging techniques for the in vivo diagnosis of Bowen's disease: Three case reports

Simona Laura Ianoși, Alexandra Batani, Mihaela Adriana Ilie, Mircea Tampa, Simona-Roxana Georgescu, Sabina Zurac, Daniel Boda, Nicolae Gabriel Ianosi, Daniela Neagoe, Daniela Calina, Cristina Tutunaru, Caruntu Constantin
Pages: 4094-4101
Published online on: 27 February 2019

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Review Open Access

Current and future applications of confocal laser scanning microscopy imaging in skin oncology (Review)

Mihaela Adriana Ilie, Constantin Caruntu, Mihai Lupu, Daniela Lixandru, Mircea Tampa, Simona-Roxana Georgescu, Alexandra Bastian, Carolina Constantin, Monica Neagu, Sabina Andrada Zurac, Daniel Boda
Pages: 4102-4111
Published online on: 25 February 2019

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Review Open Access

Vascular patterns in basal cell carcinoma: Dermoscopic, confocal and histopathological perspectives (Review)

Mihai Lupu, Constantin Caruntu, Maria Iris Popa, Vlad Mihai Voiculescu, Sabina Zurac, Daniel Boda
Pages: 4112-4125
Published online on: 25 February 2019

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Review Open Access

The 1, 2, 3, 4 of carcinoid heart disease: Comprehensive cardiovascular imaging is the mainstay of complex surgical treatment (Review)

Dinu Valentin Balanescu, Teodora Donisan, Juan Lopez-Mattei, Saamir Hassan, Peter Kim, Arvind Dasari, Daniel Halperin, James Yao, Biswajit Kar, Igor Gregoric, Serban Mihai Balanescu, Cezar Iliescu
Pages: 4126-4132
Published online on: 19 November 2018

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Review Open Access

Acanthosis nigricans: To be or not to be afraid (Review)

Maria-Linda Popa, Adrian Claudiu Popa, Cristiana Tanase, Ancuta-Augustina Gheorghisan-Galateanu
Pages: 4133-4138
Published online on: 19 November 2018

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Article Open Access

Risk factors for melanoma and skin health behaviour:An analysis on Romanian melanoma patients

Oana Fechete, Loredana Ungureanu, Simona Șenilă, Daniela Vornicescu, Sorina Dănescu, Alina Vasilovici, Elisabeta Candrea, Ștefan Cristian Vesa, Rodica Cosgarea
Pages: 4139-4144
Published online on: 19 November 2018

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Article

A 10-year retrospective study of melanoma stage at diagnosis in the academic emergency hospital of Sibiu county

Maria Rotaru, Cristina Raluca Jitian, Gabriela Mariana Iancu
Pages: 4145-4148
Published online on: 01 March 2019

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Article Open Access

Comparative analysis of CEACAM1 expression in thin melanomas with and without regression

Luciana Nichita, Sabina Zurac, Alexandra Bastian, Patricia Stinga, Roxana Nedelcu, Alice Brinzea, Gabriela Turcu, Daniela Ion, Lucia Jilaveanu, Liana Sticlaru, Cristiana Popp, Mirela Cioplea
Pages: 4149-4154
Published online on: 25 February 2019

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Review

Tumor infiltrating lymphocytes: The regulator of melanoma evolution (Review)

Mihaela Antohe, Roxana Ioana Nedelcu, Luciana Nichita, Cristiana Gabriela Popp, Mirela Cioplea, Alice Brinzea, Anastasia Hodorogea, Andreea Calinescu, Mihaela Balaban, Daniela Adriana Ion, Carmen Diaconu, Coralia Bleotu, Daniel Pirici, Sabina Andrada Zurac, Gabriela Turcu
Pages: 4155-4161
Published online on: 16 January 2019

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Review Open Access

Vitamin D receptor polymorphisms and melanoma (Review)

Alina F. Vasilovici, Lavinia Elena Grigore, Loredana Ungureanu, Oana Fechete, Elisabeta Candrea, Adrian P. Trifa, Simona Vișan, Simona Șenilă, Rodica Cosgarea
Pages: 4162-4169
Published online on: 19 November 2018

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Review

Molecular and cellular stratagem of brain metastases associated with melanoma (Review)

Ana-Maria Buga, Anca Oana Docea, Carmen Albu, Ramona Denise Malin, Daciana Elena Branisteanu, Gabriel Ianosi, Simona Laura Ianosi, Andrei Iordache, Daniela Calina
Pages: 4170-4175
Published online on: 14 January 2019

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Case Report Open Access

Complete regression of primary melanoma associated with nevi involution under BRAF inhibitors: A case report and review of the literature

Lavinia Elena Grigore, Loredana Ungureanu, Nona Bejinariu, Crina Seceac, Alina Vasilovici, Simona Corina Senila, Elisabeta Candrea, Oana Fechete, Rodica Cosgarea
Pages: 4176-4182
Published online on: 19 November 2018

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Review

Synthesis and physiological implications of melanic pigments (Review)

Minela Aida Maranduca, Daciana Branisteanu, Dragomir Nicolae Serban, Daniel Constantin Branisteanu, Gabriela Stoleriu, Nicuta Manolache, Ionela Lacramioara Serban
Pages: 4183-4187
Published online on: 25 February 2019

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Article Open Access

Development of QSAR machine learning-based models to forecast the effect of substances on malignant melanoma cells

Robert Ancuceanu, Mihaela Dinu, Iana Neaga, Fekete Gyula Laszlo, Daniel Boda
Pages: 4188-4196
Published online on: 25 February 2019

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Article Open Access

Natural killer cell monitoring in cutaneous melanoma - new dynamic biomarker

Gheorghița Isvoranu, Mihaela Surcel, Radu-Ionuț Huică, Adriana Narcisa Munteanu, Ioana Ruxandra Pîrvu, Dan Ciotaru, Carolina Constantin, Ovidiu Bratu, Monica Neagu, Cornel Ursaciuc
Pages: 4197-4206
Published online on: 25 February 2019

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Review

Crucial role of the pentose phosphate pathway in malignant tumors (Review)

Lin Jin, Yanhong Zhou
Pages: 4213-4221
Published online on: 05 March 2019

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Review

Recent advances in the molecular mechanism of sex disparity in hepatocellular carcinoma (Review)

Yanmeng Li, Anjian Xu, Siyu Jia, Jian Huang
Pages: 4222-4228
Published online on: 08 March 2019

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Article Open Access

Effects of tumor size on prognosis in differentiated thyroid carcinoma smaller than 2 cm

Ting‑Ting Zhang, Cun‑Fu Li, Shi‑Shuai Wen, Dong‑Zhe Huang, Guo‑Hua Sun, Yong‑Xue Zhu, Yu Wang, Qing‑Hai Ji, Ning Qu, Rong‑Liang Shi
Pages: 4229-4236
Published online on: 28 February 2019

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Article Open Access

Pharmacokinetic analysis for the differentiation of pituitary microadenoma subtypes through dynamic contrast‑enhanced magnetic resonance imaging

Jian Zhai, Wenqiang Zheng, Qin Zhang, Jiangfen Wu, Xuexi Zhang
Pages: 4237-4244
Published online on: 28 February 2019

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Article Open Access

A four‑gene signature for prognosis in breast cancer patients with hypermethylated IL15RA

Hui Yang, Li Zhou, Jianhua Chen, Jiang Su, Wei Shen, Biao Liu, Jundong Zhou, Shiyou Yu, Jun Qian
Pages: 4245-4254
Published online on: 12 March 2019

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Article Open Access

Sodium orthovanadate inhibits growth and triggers apoptosis of human anaplastic thyroid carcinoma cells in vitro and in vivo

Qingan Yu, Wenjing Jiang, Dan Li, Mingqi Gu, Kunpeng Liu, Liqian Dong, Chaoqun Wang, Hongchi Jiang, Wenjie Dai
Pages: 4255-4262
Published online on: 28 February 2019

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Article Open Access

Knockdown of ISOC1 suppresses cell proliferation in pancreatic cancer in vitro

Li Cheng, Yan Zhao, Maochun Tang, Zhengsheng Luo, Xingpeng Wang
Pages: 4263-4270
Published online on: 28 February 2019

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Article Open Access

Diagnostic efficacy of PET/CT in bone tumors

Songhui Han, Yanzhou Li, Yuejing Li, Min Zhao
Pages: 4271-4276
Published online on: 04 March 2019

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Article Open Access

Combination of metformin and paclitaxel suppresses proliferation and induces apoptosis of human prostate cancer cells via oxidative stress and targeting the mitochondria‑dependent pathway

Yuwan Zhao, Xin Zeng, Huancheng Tang, Dongcai Ye, Jianjun Liu
Pages: 4277-4284
Published online on: 06 March 2019

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Article Open Access

Effect of asiatic acid on epithelial‑mesenchymal transition of human alveolar epithelium A549 cells induced by TGF‑β1

Qingrong Cui, Juan Ren, Qingwei Zhou, Qinmei Yang, Bin Li
Pages: 4285-4292
Published online on: 12 March 2019

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Article Open Access

Diagnostic value analysis of combined detection of Trx, CYFRA21-1 and SCCA in lung cancer

Tao Qu, Jingwen Zhang, Ning Xu, Bo Liu, Meixiang Li, Ailing Liu, Aijun Li, Huaping Tang
Pages: 4293-4298
Published online on: 26 February 2019

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Article Open Access

Effect of miR-200c on proliferation, invasion and apoptosis of prostate cancer LNCaP cells

Jianxi Lin, Yi Lu, Xiao Zhang, Qiwang Mo, Ling Yu
Pages: 4299-4304
Published online on: 04 March 2019

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Article Open Access

Angiographic evaluation of the internal iliac artery branch in pelvic tumour patients: Diagnostic performance of multislice computed tomography angiography

Lin Li, Ketong Wu, Yang Liu, Haiyang Lai, Zhaofei Zeng, Bo Zhang
Pages: 4305-4312
Published online on: 28 February 2019

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Article Open Access

Suppressor gene GRHL1 is associated with prognosis in patients with oesophageal squamous cell carcinoma

Mengyan Li, Zhuo Li, Xinyuan Guan, Yanru Qin
Pages: 4313-4320
Published online on: 25 February 2019

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Article Open Access

Identification of key genes involved in the metastasis of clear cell renal cell carcinoma

Wenhao Wei, Yufeng Lv, Zuhuan Gan, Yanxian Zhang, Xueqiong Han, Zihai Xu
Pages: 4321-4328
Published online on: 08 March 2019

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Article Open Access

AMP‑activated protein kinase α1 serves a carcinogenic role via regulation of vascular endothelial growth factor expression in patients with non‑small cell lung cancer

Gong Dao Hui, Wang Yu Xiu, Chen Yong, Chi Bei Yuan, Zhang Jun, Gu Jian Jun, Yang Jun Jun, Xu Xing Xiang, Hu Su Wei, Min Ling Feng
Pages: 4329-4334
Published online on: 08 March 2019

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Article Open Access

Correlation of OGR1 with proliferation and apoptosis of breast cancer cells

Jianguo Zhang, Lei Che, Wenkai Sun, Jian Shang, Min Hao, Mengzi Tian
Pages: 4335-4340
Published online on: 06 March 2019

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Article Open Access

Differential expression profiles of the transcriptome in bone marrow‑derived cells in lung cancer revealed by next generation sequencing and bioinformatics

Wei‑An Chang, Ying‑Ming Tsai, Yu‑Chen Tsai, Cheng‑Ying Wu, Kuo‑Feng Chang, Chi‑Tun Lien, Jen‑Yu Hung, Ya‑Ling Hsu, Po‑Lin Kuo
Pages: 4341-4350
Published online on: 28 February 2019

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Article

Upregulated forkhead‑box A3 elevates the expression of forkhead‑box A1 and forkhead‑box A2 to promote metastasis in esophageal cancer

Bing Chen, Jiegen Yu, Linming Lu, Fangyuan Dong, Fangfang Zhou, Xiangxiang Tao, Entao Sun
Pages: 4351-4360
Published online on: 26 February 2019

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Article

Demethylation of the HACE1 gene promoter inhibits the proliferation of human liver cancer cells

Zhijun Yu, Yinyin Li, Tao Han, Zhaozhe Liu
Pages: 4361-4368
Published online on: 12 March 2019

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Article Open Access

Construction of lncRNA-mediated ceRNA network to reveal clinically relevant lncRNA biomarkers in glioblastomas

Xiang-Yang Zan, Luo Li
Pages: 4369-4374
Published online on: 05 March 2019

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Article Open Access

Identifying the optimal target genes associated with multiple myeloma by a novel bioinformatical analysis

Yan Xue, Hongmiao Liu, Guangchen Nie, Jing Zhang
Pages: 4375-4382
Published online on: 04 March 2019

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Article Open Access

Clinical significance of BRCA1 and BRCA2 mRNA and protein expression in patients with sporadic gastric cancer

Hee Sung Kim, In Gyu Hwang, Hye Young Min, Yung‑Jue Bang, Woo Ho Kim
Pages: 4383-4392
Published online on: 08 March 2019

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Article Open Access

Knockdown of cell division cycle‑associated protein 4 expression inhibits proliferation of triple negative breast cancer MDA‑MB‑231 cells in vitro and in vivo

Sen Pang, Yuju Xu, Jun Chen, Guibin Li, Jingle Huang, Xianghua Wu
Pages: 4393-4400
Published online on: 26 February 2019

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Article Open Access

High expression of TRIM36 is associated with radiosensitivity in gastric cancer

Zhongsong Man, Tao Chen, Zhongwei Zhu, Haitao Zhang, Lei Ao, Liting Xi, Jin Zhou, Zaixiang Tang
Pages: 4401-4408
Published online on: 07 March 2019

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Article Open Access

RANBP9 suppresses tumor proliferation in colorectal cancer

Chunzhi Qin, Qin Zhang, Guangbin Wu
Pages: 4409-4416
Published online on: 08 March 2019

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Article Open Access

Expression of miR‑26b in ovarian carcinoma tissues and its correlation with clinicopathology

Jianjun Lu, Wei Zhang, Yang Ding, Xiang Li, Jiandong Song
Pages: 4417-4422
Published online on: 05 March 2019

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Article Open Access

Efficacy and association analysis of high‑dose methotrexate in the treatment of children with acute lymphoblastic leukemia

Fangwei Gong, Qingjun Meng, Chengjuan Liu, Yeqi Zhao
Pages: 4423-4428
Published online on: 08 March 2019

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Article Open Access

5‑Fluorouracil‑based adjuvant chemotherapy improves the clinical outcomes of patients with lymphovascular invasion of upper urinary tract cancer and low expression of dihydropyrimidine dehydrogenase

Takahiro Narimatsu, Tsunehito Kambara, Hideyuki Abe, Toshitaka Uematsu, Yuumi Tokura, Issei Suzuki, Kazumasa Sakamoto, Kouhei Takei, Daisaku Nishihara, Gaku Nakamura, Hidetoshi Kokubun, Hideo Yuki, Hironori Betsunoh, Takao Kamai
Pages: 4429-4436
Published online on: 28 February 2019

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Article Open Access

Expression of miR‑490‑5p, miR‑148a‑3p and miR‑608 in bladder cancer and their effects on the biological characteristics of bladder cancer cells

Min Xiang, Wuxiong Yuan, Weiwei Zhang, Jie Huang
Pages: 4437-4442
Published online on: 12 March 2019

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Article Open Access

Application of sevoflurane inhalation combined with epidural anesthesia in patients with colorectal cancer and its effect on postoperative perceptual function

Xiaomin Zhang, Hao Jiang
Pages: 4443-4448
Published online on: 26 February 2019

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Article Open Access

Effect of submucosal injection of normal saline and glycerol fructose on endoscopic polypectomy in patients with colorectal polyps

Haowen Wang, Shuangshuang Wang
Pages: 4449-4454
Published online on: 06 March 2019

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Article Open Access

Cyclin A is a reliable proliferation marker in endometrial cancer cell lines

Kayo Horie, Hayate Yamamoto, Kouhei Karube, Kai Takebayashi, Hironori Yoshino, Haruhiko Yoshioka, Jun Watanabe
Pages: 4455-4462
Published online on: 08 March 2019

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Article Open Access

Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer Retraction in /10.3892/ol.2025.15388

Su‑Liang Li, Na An, Bing Liu, Sheng‑Yu Wang, Jian‑Jun Wang, Yun Ye
Pages: 4463-4473
Published online on: 05 March 2019

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Article Open Access

Five‑long non‑coding RNA risk score system for the effective prediction of gastric cancer patient survival

Zunqi Hu, Dejun Yang, Yuan Tang, Xin Zhang, Ziran Wei, Hongbing Fu, Jiapeng Xu, Zhenxin Zhu, Qingping Cai
Pages: 4474-4486
Published online on: 08 March 2019

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Article Open Access

c‑Myc maintains the self‑renewal and chemoresistance properties of colon cancer stem cells

Huan‑Le Zhang, Ping Wang, Miao‑Zhen Lu, San‑Dian Zhang, Lu Zheng
Pages: 4487-4493
Published online on: 28 February 2019

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Article Open Access

Candidate genes and potential mechanisms for chemoradiotherapy sensitivity in locally advanced rectal cancer

Chunsheng Li, Changyong E, Yangyang Zhou, Wei Yu
Pages: 4494-4504
Published online on: 28 February 2019

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Article Open Access

Polydatin inhibits hepatocellular carcinoma via the AKT/STAT3‑FOXO1 signaling pathway Corrigendum in /10.3892/ol.2019.10856

Jian Jiang, Yaodong Chen, Tianxiu Dong, Minlu Yue, Yu Zhang, Tingting An, Jiuwei Zhang, Pengfei Liu, Xiuhua Yang
Pages: 4505-4513
Published online on: 07 March 2019

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Article Open Access

Metadherin overexpression in perihilar cholangiocarcinoma is associated with lymph node metastasis and poor prognosis

Yan‑Zhi Zhu, Ke Zhou, Lin‑Lin Ruan, Fu Sun, Gen Wang, Wen‑Fang Li
Pages: 4514-4520
Published online on: 12 March 2019

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Article Open Access

Cytokines secreted by human Wharton's jelly stem cells inhibit the proliferation of ovarian cancer (OVCAR3) cells in vitro

Gauthaman Kalamegam, Khalid Hussein Wali Sait, Nisreen Anfinan, Roaa Kadam, Farid Ahmed, Mahmood Rasool, Mohammad Imran Naseer, Peter Natesan Pushparaj, Mohammed Al‑Qahtani
Pages: 4521-4531
Published online on: 01 March 2019

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Label‑free microfluidic chip for the identification of mesothelial cell clusters in pleural effusion

Lili Zhao, Meng Zhao, Yu Yang, Yajun Gu, Fang Zheng, Xuan Wang, Zhiyuan Zheng, Xuguo Sun
Pages: 4532-4544
Published online on: 06 March 2019

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Value of differential diagnosis of contrast‑enhanced ultrasound in benign and malignant thyroid nodules with microcalcification

Zhixiang Gao, Qin Lu, Jiping Yan
Pages: 4545-4549
Published online on: 04 March 2019

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Expression of LDH and CEA in serum in the process of targeted therapy of lung adenocarcinoma and the association between them and prognosis

Guangsi He, Zonghui Jiang, Song Xue, Xiaoyan Sun, Weifei Wang
Pages: 4550-4556
Published online on: 05 March 2019

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Article Open Access

Stromal tumor‑infiltrating lymphocytes evaluated on H&E‑stained slides are an independent prognostic factor in epithelial ovarian cancer and ovarian serous carcinoma

Chungsu Hwang, So Jung Lee, Jung Hee Lee, Ki Hyung Kim, Dong Soo Suh, Byung‑Su Kwon, Kyung Un Choi
Pages: 4557-4565
Published online on: 01 March 2019

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The potential role of miR‑126, miR‑21 and miR‑10b as prognostic biomarkers in renal cell carcinoma

Jessica Carlsson, Jesper Christiansen, Sabina Davidsson, Francesca Giunchi, Michelangelo Fiorentino, Pernilla Sundqvist
Pages: 4566-4574
Published online on: 12 March 2019

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Expression of p53 and PTEN in human primary endometrial carcinomas: Clinicopathological and immunohistochemical analysis and study of their concomitant expression

Aggelis Stavropoulos, Michail Varras, Thivi Vasilakaki, Viktoria‑Konstantina Varra, Aikaterini Tsavari, Fani‑Niki Varra, Aphrodite Nonni, Nikolaos Kavantzas, Andreas C. Lazaris
Pages: 4575-4589
Published online on: 01 March 2019

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Article Open Access

Influence of obesity on surgical complications of patients with ovarian tumors

Huimin Lv, Suhui Wu
Pages: 4590-4594
Published online on: 04 March 2019

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Article Open Access

Correlation of miR-425-5p and IL-23 with pancreatic cancer

Yanmin Lu, Xinqing Wu, Jinxiang Wang
Pages: 4595-4599
Published online on: 04 March 2019

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Article Open Access

Distinctive clinicopathological features of Von Hippel‑Lindau‑associated hereditary renal cell carcinoma: A single‑institution study

Baoan Hong, Zhongyuan Zhang, Jingcheng Zhou, Kaifang Ma, Jiufeng Zhang, Lin Cai, Ning Zhang, Kan Gong
Pages: 4600-4606
Published online on: 01 March 2019

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Article Open Access

Interleukin‑8 promotes prostate cancer bone metastasis through upregulation of bone sialoprotein

Baohao Liu, Meng Xu, Zhongqing Guo, Jiajie Liu, Xu Chu, Huamao Jiang
Pages: 4607-4613
Published online on: 12 March 2019

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Evaluation of the prognostic significances of γ‑secretase genes in pancreatic cancer

Yun Ho Jeon, Mihyang Ha, Sung Won Kim, Mun Ju Kim, Chi‑Seung Lee, Chang‑Kyu Oh, Myoung‑Eun Han, Sae‑Ock Oh, Yun Hak Kim
Pages: 4614-4620
Published online on: 05 March 2019

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Article Open Access

Expression of CLDN6 in tissues of gastric cancer patients: Association with clinical pathology and prognosis

Fangmei Gao, Mingdong Li, Rui Xiang, Xin Zhou, Lianying Zhu, Yi Zhai
Pages: 4621-4625
Published online on: 08 March 2019

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Article Open Access

Expression and clinical significance of SLP-2 in ovarian tumors

Jingjing Zhang, Xiucai Song, Cuihong Li, Yanjie Tian
Pages: 4626-4632
Published online on: 05 March 2019

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Linc‑pint inhibits early stage pancreatic ductal adenocarcinoma growth through TGF‑β pathway activation

Huimin Lu, Dujiang Yang, Ling Zhang, Shan Lu, Jun Ye, Mao Li, Weiming Hu
Pages: 4633-4639
Published online on: 05 March 2019

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Article

Overexpression of malignant brain tumor domain containing protein 1 predicts a poor prognosis of prostate cancer

Wanhua Wu, Shoumin Bai, Dingjun Zhu, Kaiwen Li, Wen Dong, Wang He, Shengmeng Peng, Yiming Lai, Qiong Wang, Zhenghui Guo, Leyuan Liu, Hai Huang
Pages: 4640-4646
Published online on: 05 March 2019

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Article

The stem cell‑specific intermediate filament nestin missense variation p.A1199P is associated with pancreatic cancer

Yoko Matsuda, Masashi Tanaka, Motoji Sawabe, Seijiro Mori, Masaaki Muramatsu, Makiko Naka Mieno, Toshiyuki Ishiwata, Tomio Arai
Pages: 4647-4654
Published online on: 04 March 2019

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Article

IL‑32 expression indicates unfavorable prognosis in patients with colon cancer

Jing‑Ming Zhai, Yan‑Hui An, Wei Wang, Yong‑Gang Fan, Guo‑Liang Yao
Pages: 4655-4660
Published online on: 12 March 2019

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Article

Comparison of diagnostic methods for the detection of a BRAF mutation in papillary thyroid cancer

Jingzhu Zhao, Pengpeng Liu, Yang Yu, Jingtai Zhi, Xiangqian Zheng, Jinpu Yu, Ming Gao
Pages: 4661-4666
Published online on: 08 March 2019

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Article

TNFAIP8 promotes cisplatin resistance in cervical carcinoma cells by inhibiting cellular apoptosis

Suxia Wu, Weihua Li, Zhenghui Wu, Tianran Cheng, Ping Wang, Na Li, Xiaonan Liang, Mengmeng Chi, Shuman Zhang, Yuanfang Ma, Yanyun Li, Lihui Chai
Pages: 4667-4674
Published online on: 26 February 2019

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Article

Aspirin inhibits colon cancer cell line migration through regulating epithelial‑mesenchymal transition via Wnt signaling

Shenghang Jin, Xianguo Wu
Pages: 4675-4682
Published online on: 28 February 2019

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Article

Identification of key pathways and genes in nasopharyngeal carcinoma using bioinformatics analysis

Hong‑Ming Zhu, Qian Fei, Lu‑Xi Qian, Bao‑Ling Liu, Xia He, Li Yin
Pages: 4683-4694
Published online on: 08 March 2019

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Article

Investigation of the clonal origin of multifocal papillary thyroid carcinoma according to the X‑chromosome inactivation pattern

Dan Chen, Wenjing Qi, Suling Xie, Lu Feng, Junying Wang, Lifen Wang, Hongwei Guan
Pages: 4695-4700
Published online on: 04 March 2019

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Article

Randomized controlled trial of lobaplatin plus etoposide vs. cisplatin plus etoposide as first‑line therapy in patients with extensive‑stage small cell lung cancer

Ying Cheng, Yun Fan, Xiaoqing Liu, Yunpeng Liu, Jiwei Liu, Dong Wang, Yan Yu, Shukui Qin, Wei Liu, Cheng Huang, Helong Zhang, Jun Liang, Jianhua Shi, Lijun Sheng, Hao Yu
Pages: 4701-4709
Published online on: 08 March 2019

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Article

L‑Lactate dehydrogenase B may be a predictive marker for sensitivity to anti‑EGFR monoclonal antibodies in colorectal cancer cell lines

Ayumu Nagamine, Takuya Araki, Daisuke Nagano, Mitsue Miyazaki, Koujirou Yamamoto
Pages: 4710-4716
Published online on: 26 February 2019

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Article

Clinical effect of postoperative chemoradiotherapy in resected advanced laryngeal squamous cell carcinoma

Ming Zhang, Weiye Deng, Hongli Gong, Cai Li, Yifan Wang, Xiangyu Liu, Lei Tao, Liang Zhou
Pages: 4717-4725
Published online on: 04 March 2019

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Article

Association between TP53 genetic polymorphisms and the methylation and expression of miR‑34a, 34b/c in colorectal cancer tissues

Hak Hoon Jun, Kyubum Kwack, Keun Hee Lee, Jung Oh Kim, Han Sung Park, Chang Soo Ryu, Jeong Yong Lee, Daeun Ko, Jong Woo Kim, Nam Keun Kim
Pages: 4726-4734
Published online on: 01 March 2019

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Article

Discovery of LDD‑1075 as a potent FLT3 inhibitor

Kyoung Bin Yoon, Hyo Jeong Lee, Hye Jin Chung, Jungeun Lee, Jungil Choi, Jeong Doo Heo, Yong‑Chul Kim, Sun‑Young Han
Pages: 4735-4741
Published online on: 01 March 2019

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Retraction Open Access

[Retracted] Aspirin inhibits growth of ovarian cancer by upregulating caspase-3 and downregulating bcl-2

Lin Li, Xiaogang Mao, Xiaomin Qin, Min Zhou, Hui Xing, Fan Dong, Xiaoyuan Jiang, Wenhui Zhuang
Pages: 4742-4742
Published online on: 04 March 2019

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Journal Cover
May-2026 Volume 31 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

TBX20 regulates epithelial‑mesenchymal transition, maintains tumor stemness and immune factor expression, and promotes immune escape in lung cancer

Chuncai Xu, Peng Zhou, Yanting Zhang, Lili Li, Guowen Wang
Article Number: 207
Published online on: 30 March 2026

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Article Open Access

Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
Article Number: 206
Published online on: 30 March 2026

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Article

Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
Published online on: 30 March 2026

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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
Article Number: 204
Published online on: 30 March 2026

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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
Article Number: 203
Published online on: 30 March 2026

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Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
Article Number: 202
Published online on: 30 March 2026

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Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
Article Number: 201
Published online on: 30 March 2026

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Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

Ruoxuan Li, Luping Pan, Fujuan Zeng, Jingyu Huang, Ziye Chen, Chengyi Liu, Zhimin Zeng
Article Number: 200
Published online on: 30 March 2026

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Article Open Access

Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
Article Number: 199
Published online on: 30 March 2026

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Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
Article Number: 198
Published online on: 27 March 2026

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Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
Article Number: 197
Published online on: 26 March 2026

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Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
Published online on: 26 March 2026

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Review Open Access

Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
Article Number: 195
Published online on: 26 March 2026

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Case Report Open Access

A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
Article Number: 194
Published online on: 26 March 2026

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Article Open Access

Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Review Open Access

Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Article Open Access

Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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Article Open Access

SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
Article Number: 190
Published online on: 24 March 2026

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Case Report Open Access

Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
Published online on: 24 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
Article Number: 188
Published online on: 23 March 2026

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Case Report Open Access

Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Article Open Access

Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
Article Number: 186
Published online on: 19 March 2026

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Article Open Access

Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
Article Number: 185
Published online on: 19 March 2026

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Review Open Access

Metabolic reprogramming‑a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review)

Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Article Open Access

Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 183
Published online on: 18 March 2026

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Article Open Access

Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
Published online on: 18 March 2026

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Article Open Access

Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
Article Number: 180
Published online on: 17 March 2026

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Correction Open Access

[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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Article

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
Article Number: 178
Published online on: 17 March 2026

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Case Report

Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Case Report

Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Review

Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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Retraction Open Access

[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Case Report Open Access

Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Article

Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Article Open Access

Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Article Open Access

Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Article Open Access

Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 31 Issue 6

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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