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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2019 Volume 17 Issue 5

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Editorial Open Access

[Editorial] The 2nd Conference of the Romanian Society of Immuno‑Dermatology, Bucharest, September 27-29, 2018

Monica Neagu, Daniel Boda
Pages: 4053-4054
Published online on: 27 February 2019

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Article Open Access

Dendritic cell distribution in mycosis fungoides vs. inflammatory dermatosis and other T-cell skin lymphoma

Mirela Cioplea, Costin Caruntu, Sabina Zurac, Alexandra Bastian, Liana Sticlaru, Alexandra Cioroianu, Daniel Boda, Gheorghita Jugulete, Luciana Nichita, Cristiana Popp
Pages: 4055-4059
Published online on: 01 March 2019

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Review Open Access

Angiogenesis in cutaneous T‑cell lymphoma ‑ proteomic approaches (Review)

Cristiana Tanase, Ionela Daniela Popescu, Ana‑Maria Enciu, Ancuta Augustina Gheorghisan‑Galateanu, Elena Codrici, Simona Mihai, Lucian Albulescu, Laura Necula, Radu Albulescu
Pages: 4060-4067
Published online on: 19 November 2018

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Review Open Access

Inflammation: A key process in skin tumorigenesis (Review)

Monica Neagu, Carolina Constantin, Constantin Caruntu, Carmen Dumitru, Mihaela Surcel, Sabina Zurac
Pages: 4068-4084
Published online on: 19 November 2018

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Review

Photodynamic therapy: A hot topic in dermato-oncology (Review)

Mircea Tampa, Maria-Isabela Sarbu, Clara Matei, Cristina-Iulia Mitran, Madalina-Irina Mitran, Constantin Caruntu, Carolina Constantin, Monica Neagu, Simona-Roxana Georgescu
Pages: 4085-4093
Published online on: 16 January 2019

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Case Report Open Access

Non-invasive imaging techniques for the in vivo diagnosis of Bowen's disease: Three case reports

Simona Laura Ianoși, Alexandra Batani, Mihaela Adriana Ilie, Mircea Tampa, Simona-Roxana Georgescu, Sabina Zurac, Daniel Boda, Nicolae Gabriel Ianosi, Daniela Neagoe, Daniela Calina, Cristina Tutunaru, Caruntu Constantin
Pages: 4094-4101
Published online on: 27 February 2019

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Review Open Access

Current and future applications of confocal laser scanning microscopy imaging in skin oncology (Review)

Mihaela Adriana Ilie, Constantin Caruntu, Mihai Lupu, Daniela Lixandru, Mircea Tampa, Simona-Roxana Georgescu, Alexandra Bastian, Carolina Constantin, Monica Neagu, Sabina Andrada Zurac, Daniel Boda
Pages: 4102-4111
Published online on: 25 February 2019

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Review Open Access

Vascular patterns in basal cell carcinoma: Dermoscopic, confocal and histopathological perspectives (Review)

Mihai Lupu, Constantin Caruntu, Maria Iris Popa, Vlad Mihai Voiculescu, Sabina Zurac, Daniel Boda
Pages: 4112-4125
Published online on: 25 February 2019

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Review Open Access

The 1, 2, 3, 4 of carcinoid heart disease: Comprehensive cardiovascular imaging is the mainstay of complex surgical treatment (Review)

Dinu Valentin Balanescu, Teodora Donisan, Juan Lopez-Mattei, Saamir Hassan, Peter Kim, Arvind Dasari, Daniel Halperin, James Yao, Biswajit Kar, Igor Gregoric, Serban Mihai Balanescu, Cezar Iliescu
Pages: 4126-4132
Published online on: 19 November 2018

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Review Open Access

Acanthosis nigricans: To be or not to be afraid (Review)

Maria-Linda Popa, Adrian Claudiu Popa, Cristiana Tanase, Ancuta-Augustina Gheorghisan-Galateanu
Pages: 4133-4138
Published online on: 19 November 2018

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Article Open Access

Risk factors for melanoma and skin health behaviour:An analysis on Romanian melanoma patients

Oana Fechete, Loredana Ungureanu, Simona Șenilă, Daniela Vornicescu, Sorina Dănescu, Alina Vasilovici, Elisabeta Candrea, Ștefan Cristian Vesa, Rodica Cosgarea
Pages: 4139-4144
Published online on: 19 November 2018

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Article

A 10-year retrospective study of melanoma stage at diagnosis in the academic emergency hospital of Sibiu county

Maria Rotaru, Cristina Raluca Jitian, Gabriela Mariana Iancu
Pages: 4145-4148
Published online on: 01 March 2019

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Article Open Access

Comparative analysis of CEACAM1 expression in thin melanomas with and without regression

Luciana Nichita, Sabina Zurac, Alexandra Bastian, Patricia Stinga, Roxana Nedelcu, Alice Brinzea, Gabriela Turcu, Daniela Ion, Lucia Jilaveanu, Liana Sticlaru, Cristiana Popp, Mirela Cioplea
Pages: 4149-4154
Published online on: 25 February 2019

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Review

Tumor infiltrating lymphocytes: The regulator of melanoma evolution (Review)

Mihaela Antohe, Roxana Ioana Nedelcu, Luciana Nichita, Cristiana Gabriela Popp, Mirela Cioplea, Alice Brinzea, Anastasia Hodorogea, Andreea Calinescu, Mihaela Balaban, Daniela Adriana Ion, Carmen Diaconu, Coralia Bleotu, Daniel Pirici, Sabina Andrada Zurac, Gabriela Turcu
Pages: 4155-4161
Published online on: 16 January 2019

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Review Open Access

Vitamin D receptor polymorphisms and melanoma (Review)

Alina F. Vasilovici, Lavinia Elena Grigore, Loredana Ungureanu, Oana Fechete, Elisabeta Candrea, Adrian P. Trifa, Simona Vișan, Simona Șenilă, Rodica Cosgarea
Pages: 4162-4169
Published online on: 19 November 2018

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Review

Molecular and cellular stratagem of brain metastases associated with melanoma (Review)

Ana-Maria Buga, Anca Oana Docea, Carmen Albu, Ramona Denise Malin, Daciana Elena Branisteanu, Gabriel Ianosi, Simona Laura Ianosi, Andrei Iordache, Daniela Calina
Pages: 4170-4175
Published online on: 14 January 2019

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Case Report Open Access

Complete regression of primary melanoma associated with nevi involution under BRAF inhibitors: A case report and review of the literature

Lavinia Elena Grigore, Loredana Ungureanu, Nona Bejinariu, Crina Seceac, Alina Vasilovici, Simona Corina Senila, Elisabeta Candrea, Oana Fechete, Rodica Cosgarea
Pages: 4176-4182
Published online on: 19 November 2018

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Review

Synthesis and physiological implications of melanic pigments (Review)

Minela Aida Maranduca, Daciana Branisteanu, Dragomir Nicolae Serban, Daniel Constantin Branisteanu, Gabriela Stoleriu, Nicuta Manolache, Ionela Lacramioara Serban
Pages: 4183-4187
Published online on: 25 February 2019

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Article Open Access

Development of QSAR machine learning-based models to forecast the effect of substances on malignant melanoma cells

Robert Ancuceanu, Mihaela Dinu, Iana Neaga, Fekete Gyula Laszlo, Daniel Boda
Pages: 4188-4196
Published online on: 25 February 2019

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Article Open Access

Natural killer cell monitoring in cutaneous melanoma - new dynamic biomarker

Gheorghița Isvoranu, Mihaela Surcel, Radu-Ionuț Huică, Adriana Narcisa Munteanu, Ioana Ruxandra Pîrvu, Dan Ciotaru, Carolina Constantin, Ovidiu Bratu, Monica Neagu, Cornel Ursaciuc
Pages: 4197-4206
Published online on: 25 February 2019

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Review

Crucial role of the pentose phosphate pathway in malignant tumors (Review)

Lin Jin, Yanhong Zhou
Pages: 4213-4221
Published online on: 05 March 2019

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Review

Recent advances in the molecular mechanism of sex disparity in hepatocellular carcinoma (Review)

Yanmeng Li, Anjian Xu, Siyu Jia, Jian Huang
Pages: 4222-4228
Published online on: 08 March 2019

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Article Open Access

Effects of tumor size on prognosis in differentiated thyroid carcinoma smaller than 2 cm

Ting‑Ting Zhang, Cun‑Fu Li, Shi‑Shuai Wen, Dong‑Zhe Huang, Guo‑Hua Sun, Yong‑Xue Zhu, Yu Wang, Qing‑Hai Ji, Ning Qu, Rong‑Liang Shi
Pages: 4229-4236
Published online on: 28 February 2019

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Article Open Access

Pharmacokinetic analysis for the differentiation of pituitary microadenoma subtypes through dynamic contrast‑enhanced magnetic resonance imaging

Jian Zhai, Wenqiang Zheng, Qin Zhang, Jiangfen Wu, Xuexi Zhang
Pages: 4237-4244
Published online on: 28 February 2019

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Article Open Access

A four‑gene signature for prognosis in breast cancer patients with hypermethylated IL15RA

Hui Yang, Li Zhou, Jianhua Chen, Jiang Su, Wei Shen, Biao Liu, Jundong Zhou, Shiyou Yu, Jun Qian
Pages: 4245-4254
Published online on: 12 March 2019

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Article Open Access

Sodium orthovanadate inhibits growth and triggers apoptosis of human anaplastic thyroid carcinoma cells in vitro and in vivo

Qingan Yu, Wenjing Jiang, Dan Li, Mingqi Gu, Kunpeng Liu, Liqian Dong, Chaoqun Wang, Hongchi Jiang, Wenjie Dai
Pages: 4255-4262
Published online on: 28 February 2019

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Article Open Access

Knockdown of ISOC1 suppresses cell proliferation in pancreatic cancer in vitro

Li Cheng, Yan Zhao, Maochun Tang, Zhengsheng Luo, Xingpeng Wang
Pages: 4263-4270
Published online on: 28 February 2019

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Article Open Access

Diagnostic efficacy of PET/CT in bone tumors

Songhui Han, Yanzhou Li, Yuejing Li, Min Zhao
Pages: 4271-4276
Published online on: 04 March 2019

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Article Open Access

Combination of metformin and paclitaxel suppresses proliferation and induces apoptosis of human prostate cancer cells via oxidative stress and targeting the mitochondria‑dependent pathway

Yuwan Zhao, Xin Zeng, Huancheng Tang, Dongcai Ye, Jianjun Liu
Pages: 4277-4284
Published online on: 06 March 2019

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Article Open Access

Effect of asiatic acid on epithelial‑mesenchymal transition of human alveolar epithelium A549 cells induced by TGF‑β1

Qingrong Cui, Juan Ren, Qingwei Zhou, Qinmei Yang, Bin Li
Pages: 4285-4292
Published online on: 12 March 2019

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Article Open Access

Diagnostic value analysis of combined detection of Trx, CYFRA21-1 and SCCA in lung cancer

Tao Qu, Jingwen Zhang, Ning Xu, Bo Liu, Meixiang Li, Ailing Liu, Aijun Li, Huaping Tang
Pages: 4293-4298
Published online on: 26 February 2019

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Article Open Access

Effect of miR-200c on proliferation, invasion and apoptosis of prostate cancer LNCaP cells

Jianxi Lin, Yi Lu, Xiao Zhang, Qiwang Mo, Ling Yu
Pages: 4299-4304
Published online on: 04 March 2019

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Article Open Access

Angiographic evaluation of the internal iliac artery branch in pelvic tumour patients: Diagnostic performance of multislice computed tomography angiography

Lin Li, Ketong Wu, Yang Liu, Haiyang Lai, Zhaofei Zeng, Bo Zhang
Pages: 4305-4312
Published online on: 28 February 2019

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Article Open Access

Suppressor gene GRHL1 is associated with prognosis in patients with oesophageal squamous cell carcinoma

Mengyan Li, Zhuo Li, Xinyuan Guan, Yanru Qin
Pages: 4313-4320
Published online on: 25 February 2019

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Article Open Access

Identification of key genes involved in the metastasis of clear cell renal cell carcinoma

Wenhao Wei, Yufeng Lv, Zuhuan Gan, Yanxian Zhang, Xueqiong Han, Zihai Xu
Pages: 4321-4328
Published online on: 08 March 2019

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Article Open Access

AMP‑activated protein kinase α1 serves a carcinogenic role via regulation of vascular endothelial growth factor expression in patients with non‑small cell lung cancer

Gong Dao Hui, Wang Yu Xiu, Chen Yong, Chi Bei Yuan, Zhang Jun, Gu Jian Jun, Yang Jun Jun, Xu Xing Xiang, Hu Su Wei, Min Ling Feng
Pages: 4329-4334
Published online on: 08 March 2019

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Article Open Access

Correlation of OGR1 with proliferation and apoptosis of breast cancer cells

Jianguo Zhang, Lei Che, Wenkai Sun, Jian Shang, Min Hao, Mengzi Tian
Pages: 4335-4340
Published online on: 06 March 2019

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Article Open Access

Differential expression profiles of the transcriptome in bone marrow‑derived cells in lung cancer revealed by next generation sequencing and bioinformatics

Wei‑An Chang, Ying‑Ming Tsai, Yu‑Chen Tsai, Cheng‑Ying Wu, Kuo‑Feng Chang, Chi‑Tun Lien, Jen‑Yu Hung, Ya‑Ling Hsu, Po‑Lin Kuo
Pages: 4341-4350
Published online on: 28 February 2019

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Article

Upregulated forkhead‑box A3 elevates the expression of forkhead‑box A1 and forkhead‑box A2 to promote metastasis in esophageal cancer

Bing Chen, Jiegen Yu, Linming Lu, Fangyuan Dong, Fangfang Zhou, Xiangxiang Tao, Entao Sun
Pages: 4351-4360
Published online on: 26 February 2019

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Article

Demethylation of the HACE1 gene promoter inhibits the proliferation of human liver cancer cells

Zhijun Yu, Yinyin Li, Tao Han, Zhaozhe Liu
Pages: 4361-4368
Published online on: 12 March 2019

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Article Open Access

Construction of lncRNA-mediated ceRNA network to reveal clinically relevant lncRNA biomarkers in glioblastomas

Xiang-Yang Zan, Luo Li
Pages: 4369-4374
Published online on: 05 March 2019

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Article Open Access

Identifying the optimal target genes associated with multiple myeloma by a novel bioinformatical analysis

Yan Xue, Hongmiao Liu, Guangchen Nie, Jing Zhang
Pages: 4375-4382
Published online on: 04 March 2019

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Article Open Access

Clinical significance of BRCA1 and BRCA2 mRNA and protein expression in patients with sporadic gastric cancer

Hee Sung Kim, In Gyu Hwang, Hye Young Min, Yung‑Jue Bang, Woo Ho Kim
Pages: 4383-4392
Published online on: 08 March 2019

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Article Open Access

Knockdown of cell division cycle‑associated protein 4 expression inhibits proliferation of triple negative breast cancer MDA‑MB‑231 cells in vitro and in vivo

Sen Pang, Yuju Xu, Jun Chen, Guibin Li, Jingle Huang, Xianghua Wu
Pages: 4393-4400
Published online on: 26 February 2019

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Article Open Access

High expression of TRIM36 is associated with radiosensitivity in gastric cancer

Zhongsong Man, Tao Chen, Zhongwei Zhu, Haitao Zhang, Lei Ao, Liting Xi, Jin Zhou, Zaixiang Tang
Pages: 4401-4408
Published online on: 07 March 2019

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Article Open Access

RANBP9 suppresses tumor proliferation in colorectal cancer

Chunzhi Qin, Qin Zhang, Guangbin Wu
Pages: 4409-4416
Published online on: 08 March 2019

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Article Open Access

Expression of miR‑26b in ovarian carcinoma tissues and its correlation with clinicopathology

Jianjun Lu, Wei Zhang, Yang Ding, Xiang Li, Jiandong Song
Pages: 4417-4422
Published online on: 05 March 2019

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Article Open Access

Efficacy and association analysis of high‑dose methotrexate in the treatment of children with acute lymphoblastic leukemia

Fangwei Gong, Qingjun Meng, Chengjuan Liu, Yeqi Zhao
Pages: 4423-4428
Published online on: 08 March 2019

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Article Open Access

5‑Fluorouracil‑based adjuvant chemotherapy improves the clinical outcomes of patients with lymphovascular invasion of upper urinary tract cancer and low expression of dihydropyrimidine dehydrogenase

Takahiro Narimatsu, Tsunehito Kambara, Hideyuki Abe, Toshitaka Uematsu, Yuumi Tokura, Issei Suzuki, Kazumasa Sakamoto, Kouhei Takei, Daisaku Nishihara, Gaku Nakamura, Hidetoshi Kokubun, Hideo Yuki, Hironori Betsunoh, Takao Kamai
Pages: 4429-4436
Published online on: 28 February 2019

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Article Open Access

Expression of miR‑490‑5p, miR‑148a‑3p and miR‑608 in bladder cancer and their effects on the biological characteristics of bladder cancer cells

Min Xiang, Wuxiong Yuan, Weiwei Zhang, Jie Huang
Pages: 4437-4442
Published online on: 12 March 2019

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Article Open Access

Application of sevoflurane inhalation combined with epidural anesthesia in patients with colorectal cancer and its effect on postoperative perceptual function

Xiaomin Zhang, Hao Jiang
Pages: 4443-4448
Published online on: 26 February 2019

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Article Open Access

Effect of submucosal injection of normal saline and glycerol fructose on endoscopic polypectomy in patients with colorectal polyps

Haowen Wang, Shuangshuang Wang
Pages: 4449-4454
Published online on: 06 March 2019

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Article Open Access

Cyclin A is a reliable proliferation marker in endometrial cancer cell lines

Kayo Horie, Hayate Yamamoto, Kouhei Karube, Kai Takebayashi, Hironori Yoshino, Haruhiko Yoshioka, Jun Watanabe
Pages: 4455-4462
Published online on: 08 March 2019

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Article Open Access

Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer Retraction in /10.3892/ol.2025.15388

Su‑Liang Li, Na An, Bing Liu, Sheng‑Yu Wang, Jian‑Jun Wang, Yun Ye
Pages: 4463-4473
Published online on: 05 March 2019

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Article Open Access

Five‑long non‑coding RNA risk score system for the effective prediction of gastric cancer patient survival

Zunqi Hu, Dejun Yang, Yuan Tang, Xin Zhang, Ziran Wei, Hongbing Fu, Jiapeng Xu, Zhenxin Zhu, Qingping Cai
Pages: 4474-4486
Published online on: 08 March 2019

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Article Open Access

c‑Myc maintains the self‑renewal and chemoresistance properties of colon cancer stem cells

Huan‑Le Zhang, Ping Wang, Miao‑Zhen Lu, San‑Dian Zhang, Lu Zheng
Pages: 4487-4493
Published online on: 28 February 2019

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Article Open Access

Candidate genes and potential mechanisms for chemoradiotherapy sensitivity in locally advanced rectal cancer

Chunsheng Li, Changyong E, Yangyang Zhou, Wei Yu
Pages: 4494-4504
Published online on: 28 February 2019

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Article Open Access

Polydatin inhibits hepatocellular carcinoma via the AKT/STAT3‑FOXO1 signaling pathway Corrigendum in /10.3892/ol.2019.10856

Jian Jiang, Yaodong Chen, Tianxiu Dong, Minlu Yue, Yu Zhang, Tingting An, Jiuwei Zhang, Pengfei Liu, Xiuhua Yang
Pages: 4505-4513
Published online on: 07 March 2019

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Article Open Access

Metadherin overexpression in perihilar cholangiocarcinoma is associated with lymph node metastasis and poor prognosis

Yan‑Zhi Zhu, Ke Zhou, Lin‑Lin Ruan, Fu Sun, Gen Wang, Wen‑Fang Li
Pages: 4514-4520
Published online on: 12 March 2019

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Article Open Access

Cytokines secreted by human Wharton's jelly stem cells inhibit the proliferation of ovarian cancer (OVCAR3) cells in vitro

Gauthaman Kalamegam, Khalid Hussein Wali Sait, Nisreen Anfinan, Roaa Kadam, Farid Ahmed, Mahmood Rasool, Mohammad Imran Naseer, Peter Natesan Pushparaj, Mohammed Al‑Qahtani
Pages: 4521-4531
Published online on: 01 March 2019

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Label‑free microfluidic chip for the identification of mesothelial cell clusters in pleural effusion

Lili Zhao, Meng Zhao, Yu Yang, Yajun Gu, Fang Zheng, Xuan Wang, Zhiyuan Zheng, Xuguo Sun
Pages: 4532-4544
Published online on: 06 March 2019

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Article Open Access

Value of differential diagnosis of contrast‑enhanced ultrasound in benign and malignant thyroid nodules with microcalcification

Zhixiang Gao, Qin Lu, Jiping Yan
Pages: 4545-4549
Published online on: 04 March 2019

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Article Open Access

Expression of LDH and CEA in serum in the process of targeted therapy of lung adenocarcinoma and the association between them and prognosis

Guangsi He, Zonghui Jiang, Song Xue, Xiaoyan Sun, Weifei Wang
Pages: 4550-4556
Published online on: 05 March 2019

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Article Open Access

Stromal tumor‑infiltrating lymphocytes evaluated on H&E‑stained slides are an independent prognostic factor in epithelial ovarian cancer and ovarian serous carcinoma

Chungsu Hwang, So Jung Lee, Jung Hee Lee, Ki Hyung Kim, Dong Soo Suh, Byung‑Su Kwon, Kyung Un Choi
Pages: 4557-4565
Published online on: 01 March 2019

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Article Open Access

The potential role of miR‑126, miR‑21 and miR‑10b as prognostic biomarkers in renal cell carcinoma

Jessica Carlsson, Jesper Christiansen, Sabina Davidsson, Francesca Giunchi, Michelangelo Fiorentino, Pernilla Sundqvist
Pages: 4566-4574
Published online on: 12 March 2019

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Article Open Access

Expression of p53 and PTEN in human primary endometrial carcinomas: Clinicopathological and immunohistochemical analysis and study of their concomitant expression

Aggelis Stavropoulos, Michail Varras, Thivi Vasilakaki, Viktoria‑Konstantina Varra, Aikaterini Tsavari, Fani‑Niki Varra, Aphrodite Nonni, Nikolaos Kavantzas, Andreas C. Lazaris
Pages: 4575-4589
Published online on: 01 March 2019

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Article Open Access

Influence of obesity on surgical complications of patients with ovarian tumors

Huimin Lv, Suhui Wu
Pages: 4590-4594
Published online on: 04 March 2019

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Article Open Access

Correlation of miR-425-5p and IL-23 with pancreatic cancer

Yanmin Lu, Xinqing Wu, Jinxiang Wang
Pages: 4595-4599
Published online on: 04 March 2019

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Article Open Access

Distinctive clinicopathological features of Von Hippel‑Lindau‑associated hereditary renal cell carcinoma: A single‑institution study

Baoan Hong, Zhongyuan Zhang, Jingcheng Zhou, Kaifang Ma, Jiufeng Zhang, Lin Cai, Ning Zhang, Kan Gong
Pages: 4600-4606
Published online on: 01 March 2019

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Article Open Access

Interleukin‑8 promotes prostate cancer bone metastasis through upregulation of bone sialoprotein

Baohao Liu, Meng Xu, Zhongqing Guo, Jiajie Liu, Xu Chu, Huamao Jiang
Pages: 4607-4613
Published online on: 12 March 2019

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Evaluation of the prognostic significances of γ‑secretase genes in pancreatic cancer

Yun Ho Jeon, Mihyang Ha, Sung Won Kim, Mun Ju Kim, Chi‑Seung Lee, Chang‑Kyu Oh, Myoung‑Eun Han, Sae‑Ock Oh, Yun Hak Kim
Pages: 4614-4620
Published online on: 05 March 2019

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Article Open Access

Expression of CLDN6 in tissues of gastric cancer patients: Association with clinical pathology and prognosis

Fangmei Gao, Mingdong Li, Rui Xiang, Xin Zhou, Lianying Zhu, Yi Zhai
Pages: 4621-4625
Published online on: 08 March 2019

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Article Open Access

Expression and clinical significance of SLP-2 in ovarian tumors

Jingjing Zhang, Xiucai Song, Cuihong Li, Yanjie Tian
Pages: 4626-4632
Published online on: 05 March 2019

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Article Open Access

Linc‑pint inhibits early stage pancreatic ductal adenocarcinoma growth through TGF‑β pathway activation

Huimin Lu, Dujiang Yang, Ling Zhang, Shan Lu, Jun Ye, Mao Li, Weiming Hu
Pages: 4633-4639
Published online on: 05 March 2019

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Article

Overexpression of malignant brain tumor domain containing protein 1 predicts a poor prognosis of prostate cancer

Wanhua Wu, Shoumin Bai, Dingjun Zhu, Kaiwen Li, Wen Dong, Wang He, Shengmeng Peng, Yiming Lai, Qiong Wang, Zhenghui Guo, Leyuan Liu, Hai Huang
Pages: 4640-4646
Published online on: 05 March 2019

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Article

The stem cell‑specific intermediate filament nestin missense variation p.A1199P is associated with pancreatic cancer

Yoko Matsuda, Masashi Tanaka, Motoji Sawabe, Seijiro Mori, Masaaki Muramatsu, Makiko Naka Mieno, Toshiyuki Ishiwata, Tomio Arai
Pages: 4647-4654
Published online on: 04 March 2019

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Article

IL‑32 expression indicates unfavorable prognosis in patients with colon cancer

Jing‑Ming Zhai, Yan‑Hui An, Wei Wang, Yong‑Gang Fan, Guo‑Liang Yao
Pages: 4655-4660
Published online on: 12 March 2019

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Article

Comparison of diagnostic methods for the detection of a BRAF mutation in papillary thyroid cancer

Jingzhu Zhao, Pengpeng Liu, Yang Yu, Jingtai Zhi, Xiangqian Zheng, Jinpu Yu, Ming Gao
Pages: 4661-4666
Published online on: 08 March 2019

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Article

TNFAIP8 promotes cisplatin resistance in cervical carcinoma cells by inhibiting cellular apoptosis

Suxia Wu, Weihua Li, Zhenghui Wu, Tianran Cheng, Ping Wang, Na Li, Xiaonan Liang, Mengmeng Chi, Shuman Zhang, Yuanfang Ma, Yanyun Li, Lihui Chai
Pages: 4667-4674
Published online on: 26 February 2019

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Article

Aspirin inhibits colon cancer cell line migration through regulating epithelial‑mesenchymal transition via Wnt signaling

Shenghang Jin, Xianguo Wu
Pages: 4675-4682
Published online on: 28 February 2019

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Article

Identification of key pathways and genes in nasopharyngeal carcinoma using bioinformatics analysis

Hong‑Ming Zhu, Qian Fei, Lu‑Xi Qian, Bao‑Ling Liu, Xia He, Li Yin
Pages: 4683-4694
Published online on: 08 March 2019

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Article

Investigation of the clonal origin of multifocal papillary thyroid carcinoma according to the X‑chromosome inactivation pattern

Dan Chen, Wenjing Qi, Suling Xie, Lu Feng, Junying Wang, Lifen Wang, Hongwei Guan
Pages: 4695-4700
Published online on: 04 March 2019

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Article

Randomized controlled trial of lobaplatin plus etoposide vs. cisplatin plus etoposide as first‑line therapy in patients with extensive‑stage small cell lung cancer

Ying Cheng, Yun Fan, Xiaoqing Liu, Yunpeng Liu, Jiwei Liu, Dong Wang, Yan Yu, Shukui Qin, Wei Liu, Cheng Huang, Helong Zhang, Jun Liang, Jianhua Shi, Lijun Sheng, Hao Yu
Pages: 4701-4709
Published online on: 08 March 2019

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Article

L‑Lactate dehydrogenase B may be a predictive marker for sensitivity to anti‑EGFR monoclonal antibodies in colorectal cancer cell lines

Ayumu Nagamine, Takuya Araki, Daisuke Nagano, Mitsue Miyazaki, Koujirou Yamamoto
Pages: 4710-4716
Published online on: 26 February 2019

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Article

Clinical effect of postoperative chemoradiotherapy in resected advanced laryngeal squamous cell carcinoma

Ming Zhang, Weiye Deng, Hongli Gong, Cai Li, Yifan Wang, Xiangyu Liu, Lei Tao, Liang Zhou
Pages: 4717-4725
Published online on: 04 March 2019

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Article

Association between TP53 genetic polymorphisms and the methylation and expression of miR‑34a, 34b/c in colorectal cancer tissues

Hak Hoon Jun, Kyubum Kwack, Keun Hee Lee, Jung Oh Kim, Han Sung Park, Chang Soo Ryu, Jeong Yong Lee, Daeun Ko, Jong Woo Kim, Nam Keun Kim
Pages: 4726-4734
Published online on: 01 March 2019

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Article

Discovery of LDD‑1075 as a potent FLT3 inhibitor

Kyoung Bin Yoon, Hyo Jeong Lee, Hye Jin Chung, Jungeun Lee, Jungil Choi, Jeong Doo Heo, Yong‑Chul Kim, Sun‑Young Han
Pages: 4735-4741
Published online on: 01 March 2019

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Retraction Open Access

[Retracted] Aspirin inhibits growth of ovarian cancer by upregulating caspase-3 and downregulating bcl-2

Lin Li, Xiaogang Mao, Xiaomin Qin, Min Zhou, Hui Xing, Fan Dong, Xiaoyuan Jiang, Wenhui Zhuang
Pages: 4742-4742
Published online on: 04 March 2019

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Efficacy and safety of rituximab in the treatment of primary central nervous system lymphoma: A meta‑analysis and systematic review of 1,388 patients

Lichaoyue Sun, Wenshu Li, Wei Chen, Chunxing Li, Zhao Ren, Qing Xie, Dongxiao Wang
Article Number: 488
Published online on: 02 September 2026

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Review Open Access

Psychological stress and tumor progression: Molecular mechanisms and therapeutic implications (Review)

Yifei Zhang, Yajun Kong, Shuanbao Zhao
Article Number: 487
Published online on: 02 September 2026

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Article Open Access

Development and evaluation of clinical models based on ultrasound, serum CA153 and molecular subtype in predicting the efficacy of neoadjuvant chemotherapy in breast cancer

Ming-Yue Du, Shu-E Zeng
Article Number: 486
Published online on: 02 September 2026

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Article Open Access

Clinical utility of circulating tumor‑derived endothelial cells in lung cancer detection and prognosis prediction

Xiang Li, Jun Yang, Bin Chen, Ziyu Zhang, Jiangman Zhao, Mengxin Zhao, Zhimou Wang
Article Number: 485
Published online on: 02 September 2026

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Article Open Access

Construction of a new predictive model in head and neck squamous cell carcinoma based on the investigation of extracellular matrix‑associated genes

Liangqian Tu, Yiyin Qiu, Handan Zheng, Bixin Fang, Ming Chen
Article Number: 484
Published online on: 02 September 2026

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Special Issue

Inhibition or induction of gastrointestinal tumors by ferroptosis and intervention by herbal extracts (Review)

Defei Yin, Qinghua Li, Junwei Liang, Xiaoyan Yan, Dajuan Sun
Article Number: 483
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Demethylation of microRNA-142 induced by demethylation agents plays a suppressive role in osteosarcoma cells

Muliang Ding, Jianzhong Hu, Jiangdong Ni, Zhonghui Zheng, Deye Song, Junjie Wang
Article Number: 482
Published online on: 01 September 2026

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Article Open Access

CCT2 defines a highly cisplatin‑resistant and poor‑prognosis subtype of lung adenocarcinoma

Huafang Mao, Chao Su, Xiaoliang Han, Guoxia Wang
Article Number: 481
Published online on: 28 August 2026

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Expression of Concern Open Access

[Expression of Concern] Simvastatin potentiates doxorubicin activity against MCF‑7 breast cancer cells

Benjaporn Buranrat, Wanwisa Suwannaloet, Jarinyaporn Naowaboot
Article Number: 480
Published online on: 27 August 2026

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Article Open Access

Characterization of ZIC5 expression in esophageal squamous cell carcinoma and its association with patient survival

Bo Yang, Baige Wang, Haiquan Deng, Yong Luo, Shenghao Wu, Huaxin Yin, Hongdian Zhang, Yuncheng Zhang, Zhen Zhang
Article Number: 479
Published online on: 26 August 2026

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Review Open Access

Microbiome‑based diagnostic biomarkers in pancreatic ductal adenocarcinoma: Current evidence and translational challenges (Review)

Huiya Jin, Hui Sun, Jing Yang
Article Number: 478
Published online on: 26 August 2026

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Correction Open Access

[Corrigendum] Long non-coding RNA CCAT2 functions as an oncogene in hepatocellular carcinoma, regulating cellular proliferation, migration and apoptosis

Ning Zhou, Zhongzhou Si, Ting Li, Guangshun Chen, Zhongqiang Zhang, Haizhi Qi
Article Number: 477
Published online on: 26 August 2026

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Article Open Access

Efficacy and safety of ICI‑based triple combination therapy for gene‑negative advanced lung adenocarcinoma

Diwei Mo, Huan Chen, Zhihong Zhu, Jinghua Yu, Xia Yang, Yiyu Lu, Keng Wang, Guifeng Xu, Luwen Lei, Xingxi Pan
Article Number: 476
Published online on: 25 August 2026

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Correction Open Access

[Corrigendum] Angiotensin II type 2 receptor‑interacting protein 3a suppresses proliferation, migration and invasion in tongue squamous cell carcinoma via the extracellular signal‑regulated kinase‑Snai2 pathway

Tingting Zhao, Qianting He, Zhonghua Liu, Xueqiang Ding, Xiaofeng Zhou, Anxun Wang
Article Number: 475
Published online on: 24 August 2026

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Article Open Access

Pazopanib treatment for primary cardiovascular sarcoma: A retrospective observational study and literature review

Shintaro Yamanaka, Yoshihiro Yakushijin, Shinji Hasebe, Shoichiro Yamamoto, Tomomi Fujii, Riko Kitazawa, Taketsugu Fujibuchi, Teruki Kidani, Masaki Maruta
Article Number: 474
Published online on: 21 August 2026

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Case Report Open Access

Primary cutaneous angiosarcoma of the scalp initially misdiagnosed as cellulitis in a 95‑year‑old Asian man: A case report

Baopeng Qi, Qianru Li, Yuan Gao, Yuanyu Tang, Yang Yu
Article Number: 473
Published online on: 21 August 2026

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Review Open Access

Colorectal cancer and tumor vaccines (Review)

Jianshuang Ma, Congming Xiang, Dong Xia
Article Number: 472
Published online on: 21 August 2026

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Article Open Access

Pre‑radiotherapy modified prognostic nutritional index predicts acute radiation enteritis in patients with cervical cancer undergoing radiotherapy: A retrospective study

Yani Zou, Rui Huang, Wenqiang Qin, Chunqiu Wu, Wei Zhang
Article Number: 471
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] MicroRNA‑101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A

Lumin Wang, Jiayi Yao, Hongfei Sun, Kang He, Dongdong Tong, Tusheng Song, Chen Huang
Article Number: 470
Published online on: 20 August 2026

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Article Open Access

Boost delivery in hypofractionated breast cancer radiotherapy: A registry‑based analysis of treatment patterns and survival

Karoline Elisabeth Horry, Dirk Vordermark, Daniel Medenwald, Jörg Andreas Müller
Article Number: 469
Published online on: 18 August 2026

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Article

Effect of perioperative nutritional status, inflammatory response and postoperative chemotherapy on survival after gastrectomy for advanced gastric cancer

Yoshinori Fujiwara, Shunji Endo, Masaharu Higashida, Masaaki Hori, Yoko Endo, Ryoko Makieda, Akihide Fujii, Miyoko Kobayashi, Kazuhiko Yoshimatsu, Tomio Ueno
Article Number: 468
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] miR‑185‑5p targets ROCK2 and inhibits cell migration and invasion of hepatocellular carcinoma

Yuexiang Niu, Gongen Tang
Article Number: 467
Published online on: 17 August 2026

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Article

OLFML2A expression in acute myeloid leukemia, with exploratory findings in acute lymphoblastic leukemia: Prognostic significance and re‑analysis of public single‑cell transcriptomic data

Xuan Lu, Jinlian Li, Xinru Zhao, Wanchuan Zhuang, Xingxing Chai
Article Number: 466
Published online on: 17 August 2026

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Article Open Access

Identifying an appropriate endogenous control for real‑time PCR of microRNAs in colorectal liver metastases: A comparison of 18s rRNA and small nuclear RNA RNU6B

Clemens Franz, Sibylle Hartmann, Alexis Ulrich, Georgios Polychronidis, Christoph Kahlert, Fee Klupp, Mohammed Al‑Saeedi
Article Number: 465
Published online on: 17 August 2026

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Article Open Access

Analysis of DNA methylation markers for diagnosing cervical precancer and cancer: A single‑center cross‑sectional study

Xue Chen, Jialing Li, Li Tian, Xinshu Li, Jingwen Guo, Liling He, Shulian Mao, Xitang Yang, Hua Guo
Article Number: 464
Published online on: 17 August 2026

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Article Open Access

Flavokawain A inhibits high glucose‑induced malignant progression of lung cancer cells by suppressing PRMT5‑mediated PTEN neddylation and nuclear translocation

Lei Zheng, Juan Li, Chao Song, Leping Shi, Qian Zhou, Yuyao Guan
Article Number: 463
Published online on: 14 August 2026

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Review Open Access

Metabolic heterogeneity and functional diversity of cancer-associated fibroblasts in gastric cancer (Review)

Qilu Fang, Neng Lv, Shuwei Yu, Jia Wang, Wenxiu Xin
Article Number: 462
Published online on: 14 August 2026

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Article Open Access

Preoperative CA125 and metabolic factors associated with high‑risk pathology in endometrial cancer

Yinuo Wang, Yueqi Yan, Wen Sun, Yiting Gao, Bingli Qi, Xia Li, Shouze Liu, Shikai Liu
Article Number: 461
Published online on: 14 August 2026

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Article Open Access

EGR1 regulates IGF‑1‑stimulated pancreatic cancer cell invasion by increasing IL‑11 expression 

Yena Choi, Euitaek Jung, Junekyu Han, Soon Young Shin
Article Number: 460
Published online on: 13 August 2026

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Review Open Access

Claudin‑18.2: Molecular mechanisms to clinical translation in solid tumors (Review)

Minjie Zhang, Dawei Wu, Yu Tang, Ning Li, Xinhua Yan
Article Number: 459
Published online on: 12 August 2026

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Case Report Open Access

Probable cavernous sinus‑adjacent meningeal metastasis from esophageal squamous cell carcinoma: A case report

Heng Di Zhang, Bin He, Jing Jing Peng, Ting Yu, Fang Yuan Kong, Ling Zhang
Article Number: 458
Published online on: 12 August 2026

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Case Report Open Access

Immunotherapy combined with anti‑angiogenic therapy, radiotherapy and chemotherapy for the treatment of giant pelvic osteosarcoma: A case report and literature review

Qingying Yan, Jiewen Yang, Yunxia Liu, Miao Cheng, Zhen Wang, Jialu Chen, Yefeng Xu
Article Number: 457
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Obesity accelerates murine gastric cancer growth by modulating the Sirt1/YAP pathway

Hai-Jun Li, Jun-Ke Fu, Xiang-Ming Che, Lin Fan, Yong Zhang, E Bai
Article Number: 456
Published online on: 12 August 2026

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Article Open Access

Tumor suppressor syntaxin binding protein 1 regulates alternative splicing of DNA repair genes related to radiation sensitivity in breast cancer cells

Meng Zhang, Xiaoxue Zhang, Qian Rou, Ying Liu, Ailifeire Abudujiapaer, Minghui Li, Huaixiong Wang, Fang Cheng
Article Number: 455
Published online on: 12 August 2026

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Retraction Open Access

[Retracted] 2’,4’‑dihydroxychalcone, a flavonoid isolated from Herba oxytropis, suppresses PC‑3 human prostate cancer cell growth by induction of apoptosis 

Yuqing Sheng, Mingchang Zou, Yan Wang, Qiheng Li
Article Number: 454
Published online on: 11 August 2026

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Case Report Open Access

Mixed carcinoma transdifferentiation of bladder urothelial carcinoma after chemotherapy: A case report

Liwei Zhao, Jiaguo Huang, Zhanwen Dong, Ji Sun, Runmiao Hua, Xuliang Wang, Kai Wang
Article Number: 453
Published online on: 10 August 2026

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Case Report Open Access

Primary leiomyosarcoma of the lumbar soft tissue treated with multimodal therapy, including anlotinib: A case report

Jia-Huan Li, De-Xiang Liao, Zhen Hu, Zhi-Yong Zhang, Dan-Dan Ma, Wei-Dong Jin, Tao Fu
Article Number: 452
Published online on: 10 August 2026

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Expression of Concern Open Access

[Expression of Concern] Valosin‑containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NF‑κβ/beclin‑1 signaling pathway

Xin Hua Long, Yun Fei Zhou, Min Lan, Shan Hu Huang, Zhi Li Liu, Yong Shu
Article Number: 451
Published online on: 07 August 2026

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Article Open Access

Prognostic value of the CONUT score in newly diagnosed diffuse large B‑cell lymphoma

Sema Seçilmiş, Hacer Berna Afacan Öztürk, Birgül Ay Karakuş, Asena Dikyar, Kadir Acar, Ahmet Kürşad Güneş
Article Number: 450
Published online on: 06 August 2026

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Article Open Access

DHX15 as a novel immune‑related prognostic biomarker in breast cancer: An integrated bioinformatics analysis with in vitro functional validation

Fan Li, Qin Yue, Jing Li
Article Number: 449
Published online on: 05 August 2026

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Case Report Open Access

Emergence of KRAS mosaicism with multiple variants during treatment with alectinib in ALK‑positive metastatic non‑small cell lung cancer: A case report

Alizée Simon, Gautier Treffel, Guillaume Pax, Guillaume Gauchotte, Marie Husson, Idrissia Hanriot, Agnès Leroux, Jean-Louis Merlin, Alexandre Harlé, Pauline Gilson
Article Number: 448
Published online on: 05 August 2026

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Expression of Concern Open Access

[Expression of Concern] Circular RNA ATAD1 is upregulated in acute myeloid leukemia and promotes cancer cell proliferation by downregulating miR‑34b via promoter methylation  

Yarong Wu, Bingjun Gao, Xiaolei Qi, Liyun Bai, Bixin Li, Hongjing Bao, Xi Wu, Xiaoyun Wu, Yuxia Zhao
Article Number: 447
Published online on: 05 August 2026

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Article

Preliminary study on the efficacy of pazopanib combined with toripalimab as first‑line therapy for metastatic renal cell carcinoma: Real‑world data from a single center

Bin Wang, Tianjun Xing, Hongyu Liu, Xuebing Han, Kai Wu
Article Number: 446
Published online on: 05 August 2026

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Review Open Access

Subtype‑specific mechanisms of lipid metabolism in gynecological malignancies and novel targeted intervention strategies (Review)

Yidan Ran
Article Number: 445
Published online on: 04 August 2026

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Review Open Access

Chrono‑immunotherapy in genitourinary oncology: From emerging evidence to clinical translation (Review)

Osama Zein Deen, Xin Ye, Patsy Lee, Roxana Astani, Georg Bjarnason, Christian Kollmannsberger, Bernhard Eigl, Guliz Ozgun
Article Number: 444
Published online on: 03 August 2026

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Case Report Open Access

Imaging features and clinical management of mesenteric cavernous lymphangioma: A case report and literature review

Zhongze Zhao, Ermin Cai, Tong Zhou, Jianju Feng, Lingzhi Gu
Article Number: 443
Published online on: 03 August 2026

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Article Open Access

Association between the expression of GSTP1 and mutant p53, poor chemotherapy response and metastasis in patients with osteosarcoma

Bangkit Primayudha, Evelina Kodrat, Yogi Prabowo, Aryadi Kurniawan, Nurjati Chairani Siregar, Muhamad Naseh Sajadi Budi Irawan, Rahadyan Magetsari, I Gede Eka Wiratnaya, Istan Irmansyah Irsan, Achmad Fauzi Kamal
Article Number: 442
Published online on: 03 August 2026

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Article Open Access

Astragaloside IV suppresses triple‑negative breast cancer cell migration and invasion by targeting BCAT1‑mediated branched‑chain amino acid metabolism

Yi-Ting Liu, Lu Zhang, Xiao-Dong Sun
Article Number: 441
Published online on: 03 August 2026

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Article Open Access

LC‑MS/MS‑based clinical value exploration of the methionine cycle in luminal breast cancer

Wenxuan Wu, Yifeng Tu, Han Yao, Yajun Mao, Changfei Mao, Feifei Xu, Zhongcheng Wang
Article Number: 440
Published online on: 03 August 2026

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Article

Accuracy of percutaneous ultrasound‑guided needle biopsy of abdominal lymph nodes for the diagnosis of malignant disease

Camilla Mazzoni, Lisa Argnani, Davide Di Benedetto, Sofia Maria Bakken, Beatrice Casadei, Cinzia Pellegrini, Leonardo De Marco, Marta Machado, Alessandro Broccoli, Pier Luigi Zinzani, Carla Serra
Article Number: 439
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Esomeprazole affects the proliferation, metastasis, apoptosis and chemosensitivity of gastric cancer cells by regulating lncRNA/circRNA‑miRNA‑mRNA ceRNA networks

Qian Xu, Xiyun Jia, Qian Wu, Lei Shi, Zihan Ma, Nan Ba, Han Zhao, Xingzhou Xia, Zisen Zhang
Article Number: 438
Published online on: 03 August 2026

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Case Report Open Access

Papillary thyroid carcinoma in a patient with long‑standing chronic lymphocytic leukemia: A case report

Jiaxiang Ma, Tieying Gan, Ailin Song, Hongyou Tian, Shaoce Xu, Lei Zhao
Article Number: 437
Published online on: 30 July 2026

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Review Open Access

Current status and targeted therapies in endometrial cancer: Molecular classification‑driven treatment strategies (Review)

Xinyu Li, Jie Liu, Fang Huang, Xinyue Deng, Mingxuan Chen, Wen Mou, Wenxia Liu
Article Number: 436
Published online on: 30 July 2026

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Article Open Access

Role of lipid‑associated fibroblasts and their signature genes FABP4, CD36 and ABCA8 in gastric cancer progression

Junqun Liao, Lin Wu, Li Zhou, Qiao Ling, Piyun Zhang
Article Number: 435
Published online on: 30 July 2026

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Correction Open Access

[Corrigendum] Repositioning of duloxetine to target pancreatic stellate cells

Akiko Sagara, Kohei Nakata, Sokichi Matsumoto, Weiyu Guan, Tomohiko Shinkawa, Chika Iwamoto, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 434
Published online on: 30 July 2026

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Article

Influence of the second primary cancer on clinical outcomes of nasopharyngeal carcinoma following definitive chemoradiotherapy

Shu-Chin Yang, Chung-Han Ho, Li-Tsun Shieh, Sung-Wei Lee, Chia-Chun Chen, Sheng-Yow Ho
Article Number: 433
Published online on: 29 July 2026

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Review Open Access

ETS transcription factor ELK3: Molecular insights and translational horizons in cancer (Review)

Zhenzhe Liu, Zhong Wei, Zhensheng Li, Liqiang Zhou
Article Number: 432
Published online on: 29 July 2026

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Review Open Access

Bone niche‑driven antitumor immune failure in osteosarcoma: Mechanisms and therapeutic implications (Review)

Bolin Tang, Yuhuai Wu, Jianping Liu, Rui Pan
Article Number: 431
Published online on: 29 July 2026

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Article Open Access

Deep learning model based on CT images to predict Ki‑67 expression in renal carcinoma

Dan Shen, Hongmei Li, Bingye Shi, Tao Ma, Bin Zhou, Chao Gao, Yibo Liu, Zhenyu Cui
Article Number: 430
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang
Article Number: 429
Published online on: 29 July 2026

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Article Open Access

Investigation of CRP and NLR as potential biomarkers for redefining biological borderline resectable pancreatic cancer

Keishi Kawasaki, Hidehiro Tajima, Teppei Tatsuoka, Musashi Takada, Soya Meguro, Hirotaka Ishido, Hideyuki Yoshitomi
Article Number: 428
Published online on: 28 July 2026

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Article Open Access

FAM122B acts as an independent poor prognostic factor and promotes the malignant biological behaviors of low‑grade glioma

Hao Wang, Tengfei Guo, Yanbo Gao, Yi Zhou, Rongjun Qian
Article Number: 427
Published online on: 28 July 2026

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A nomogram based on immunohistochemistry and lymphocyte‑to‑monocyte ratio for predicting risk stratification in endometrial carcinoma

Yunyun Chen, Jianwei Li, Li Yan, Peili Liu, Fanfei Meng, Yajun Zhang
Article Number: 426
Published online on: 28 July 2026

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Correction Open Access

[Corrigendum] Effects of Platycodin D on apoptosis, migration, invasion and cell cycle arrest of gallbladder cancer cells

Xiaoyu Zhang, Tianyu Zhai, Zhenyu Hei, Di Zhou, Longyang Jin, Chao Han, Jiandong Wang
Article Number: 425
Published online on: 27 July 2026

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Case Report Open Access

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases 

Noriko Kato, Takashi Yanagawa, Masahiko Okamoto, Tatsuya Ohno, Hirotaka Chikuda
Article Number: 424
Published online on: 23 July 2026

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[Corrigendum] Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 423
Published online on: 23 July 2026

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November-2026 Volume 32 Issue 5

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Pan‑cancer prognostic value of TGFBR1: Bioinformatics and experimental validation with a focus on gastric cancer

Xia Zhao, Lufan Shen, Zhiyuan Gong, Mengwen Lv, Yan Zhang, Bingxi Tang, Xinli Li
Article Number: 523
Published online on: 21 September 2026

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MAD2L1 overexpression promotes breast cancer progression and confers resistance to paclitaxel via proteasomal stabilization

Shih-Ho Wang, Cheng-Hsi Yeh, Chia-Wei Wu, Chia-Yi Hsu, Eing-Mei Tsai, Chao-Ming Hung, Ming-Wei Lin, Tsung-Hua Hsieh
Article Number: 522
Published online on: 21 September 2026

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Efficacy of circulating tumour DNA in guiding postoperative adjuvant chemotherapy for resectable colorectal cancer: A meta‑analysis based on cohort studies

Jiale Ruan, Wen Shi, Wenwen Shi, Xinyan Zhang, Yixia Chen, Xiaoling Feng, Jian Song
Article Number: 521
Published online on: 21 September 2026

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Clinicopathological role of microRNA‑205, microRNA‑223 and microRNA‑590 in vulvar cancer

Edyta Leśniak, Emilia Stec‑Martyna, Bartłomiej Tomasik, Hanna Romanowicz, Oliwia Maciejewska, Jan Bieńkiewicz, Andrzej Malinowski, Miłosz Wilczyński
Article Number: 520
Published online on: 21 September 2026

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[Retracted] Regulatory effect of microRNA‑223‑3p on breast cancer cell processes via the Hippo/Yap signaling pathway

Tonghua Du, Dan Wang, Xiaoyu Wan, Jingwei Xu, Qi Xiao, Bin Liu
Article Number: 519
Published online on: 21 September 2026

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Decitabine induces cell differentiation and growth inhibition accompanied by upregulation of microRNA‑143 and MS4A3 in the myelodysplastic syndromes‑derived leukemic cell line MDS‑L

Rie Nishi, Naoko Hosono, Kaoru Thoyama, Takahiro Yamauchi
Article Number: 518
Published online on: 18 September 2026

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Malignant mesothelioma of the tunica vaginalis testis: A case report

Zhenjiang Liu, Aiyun Han, Shen Li, Jin Zhang, Yuanshan Guo, Chao Sun
Article Number: 517
Published online on: 18 September 2026

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Methyltransferase‑like 7B promotes M2‑like macrophage polarization in lung adenocarcinoma via upregulating human epidermal growth factor receptor 3 expression and secretion

Sixiao He, Huibin Song, Jie Wu, Jinquan Xia, Ni Liu, Jia Cao, Zixuan Zhang, Xiaolin Cui, Chang Zou
Article Number: 516
Published online on: 18 September 2026

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Exosomal miR‑145‑5p inhibits papillary thyroid cancer by targeting TPM3 and inactivating the PI3K‑Akt pathway

Yunfeng Weng, Xianjiao Cao, Wenyan Song, Qingqing He
Article Number: 515
Published online on: 17 September 2026

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Identification of cancer‑associated fibroblast biomarkers in cutaneous squamous cell carcinoma

Yuanyuan Deng, Jue Qi, Yu Tang, Yueting Cun, Qian He, Li He
Article Number: 514
Published online on: 17 September 2026

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Focal adhesion kinase inhibitor defactinib enhances olaparib‑induced suppression of BRCA‑proficient breast cancer cell proliferation

Hisako Ono, Keiko Taniguchi, Shusuke Yasuda, Mamiko Sukeno, Tomoya Matsui, Yasuto Naoi, Mano Horinaka, Toshiyuki Sakai
Article Number: 513
Published online on: 16 September 2026

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[Corrigendum] Lysyl oxidase‑like‑1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved

Geum-Hwa Lee, Do-Sung Kim, Myung Ja Chung, Soo-Wan Chae, Hyung-Ryong Kim, Han-Jung Chae
Article Number: 512
Published online on: 16 September 2026

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Role of tumor necrosis factor receptor superfamily member 19 in cancer: Diverse functions and therapeutic potential (Review)

Manyu Xu, Zhaoyang Liu, Jingyu Zhang, Hanyun Xu, Yufei Xu, Yue Zhang, Qiong-Ying Hu, Tao Zhang
Article Number: 511
Published online on: 15 September 2026

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Initiation of immune checkpoint inhibitor therapy in winter is associated with improved overall survival in patients with advanced non‑small cell lung cancer

Zhangxuan Chen, Jingsi Chen, Yang Yao, Xinjing Li, Ranpu Wu, Bingxue Wang, Jiajie Sun, Hongbing Liu
Article Number: 510
Published online on: 15 September 2026

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Optimal timing of stereotactic radiosurgery with first‑line osimertinib in EGFR‑mutant non‑small cell lung cancer brain metastases: Immediate, early‑consolidation and salvage strategies

Xiaona Zhuang, Xiaoxiao Lu, Junjun Miao, Guangying Hou, Xiangkun Yuan
Article Number: 509
Published online on: 15 September 2026

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Integrated analysis identified MARK4 as a prognostic and immunomodulatory biomarker in oral squamous cell carcinoma

Xinyue Zhang, Xiaoxue Shen, Sujun Hu, Rui Yao
Article Number: 508
Published online on: 15 September 2026

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Case Report Open Access

Combination of vinorelbine capsules and the small molecule anti‑angiogenic drug apatinib for first‑line treatment of advanced triple‑negative breast cancer with schizophrenia after failure of anthracycline and taxane therapy: A case report

Xue Bai, Liping Chen, Xuelian Chen, Dongcun Wang, Wenyan Kang, Lin Song, Meidi Liu, Caiwen Du
Article Number: 507
Published online on: 15 September 2026

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Basis and prospects of radiotherapy combined with high‑intensity focused ultrasound ablation (Review)

Lingli Fan, Xiyue Yang, Jie Li, Yao Liao, Yuxi Bai, Xin Mao, Li Yuan, Feng Gao, Gang Feng, Qiuling Shi, Xiaobo Du
Article Number: 506
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] Remodeling of energy metabolism by a ketone body and medium‑chain fatty acid suppressed the proliferation of CT26 mouse colon cancer cells

Yui Kadochi, Shiori Mori, Rina Fujiwara‑Tani, Yi Luo, Yukiko Nishiguchi, Shingo Kishi, Kiyomu Fujii, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 505
Published online on: 14 September 2026

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Melatonin exerts an in vitro anti‑glioblastoma effect through SIRT1‑mediated HMGB1 deacetylation and inhibition of the TLR4/NF‑κB pathway

Beitian Shi, Yu Wang, Chao Zhang, Shiqiang Hou, Ning Lin, Lanlan Zhang
Article Number: 504
Published online on: 14 September 2026

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Case Report Open Access

Concurrent EGFR exon 19 deletion‑insertion and germline BRCA1 alteration in KRAS‑wild‑type pancreatic ductal adenocarcinoma: A case report and review of therapeutic implications

Sheng Yu Wei, Wei Yu, Qiao Huang
Article Number: 503
Published online on: 14 September 2026

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Effect of extracellular vesicles on malignant tumours: Mechanisms and clinical findings (Review)

Ruiyi Shen, Qihong Lan, Yuan Lu, Ke Wen, Zhenzhen Wei, Qian Liu
Article Number: 502
Published online on: 11 September 2026

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Circulating PCSK9: A new frontier in cancer risk stratification for obese diabetics

Lien-Cheng Tsao, Chen-Ling Kuo, Yu-Shan Cheng, Ching-Shan Huang, Chin-San Liu, Shih-Li Su
Article Number: 501
Published online on: 11 September 2026

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Multifaceted roles of chemokines in gastric cancer: From tumor microenvironment modulation to therapeutic targeting (Review)

Zhanping Li, Zhongdang Xiao
Article Number: 500
Published online on: 11 September 2026

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Identification and assessment of FN1, MET, KRT19 and CLDN1 as key dysregulated genes in papillary thyroid cancer through transcriptomic profiling and expression analysis

Anette Roxana Gastelum‑Quiroz, Noemí García‑Magallanes, Andrea Ross‑Orozco, Marco Alvarez‑Arrazola, Fred Luque‑Ortega, Karla Lizbeth Morales‑Hernández, Dora Cedano‑Prieto, Vanessa G. Félix, Eliakym Arámbula‑Meraz
Article Number: 499
Published online on: 11 September 2026

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Correction Open Access

[Corrigendum] Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 498
Published online on: 10 September 2026

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Article

Integrated bioinformatics and feature selection-based discovery of ADP-ribosylation-associated biomarkers in non-small cell lung cancer

Jie He, Qingtao Zhao, Hongzhen Zhao, Hua Zhang, Zhonghui Hu, Lingxin Kong, Zengming Wang, Jianghong Yan, Shuo Yang, Shicheng Liu
Article Number: 497
Published online on: 08 September 2026

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Review Open Access

Mechanism‑guided radiosensitization strategies for nasopharyngeal carcinoma: Current evidence and translational perspectives (Review)

Wei Deng, Ziyun Li, Zhenhua Zhu
Article Number: 496
Published online on: 08 September 2026

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Retraction Open Access

[Retracted] Characterization of sonic hedgehog inhibition in gastric carcinoma cells

Ruxue Bai, Hongchuan Zhao, Xiang Zhang, Shiyu Du
Article Number: 495
Published online on: 08 September 2026

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Article Open Access

KLF2 as a prognostic and potential therapeutic target associated with ferroptosis in serous ovarian cancer: An integrative bioinformatics and clinical validation study

Yuanyi Wang, Juan Yu, Wu Huang, Yuan Yuan, Xiangbo Lan, Youli Jian, Xiao Li, Simei Wang, Xiao Huang, Ge Xu, Xing Wei
Article Number: 494
Published online on: 07 September 2026

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Case Report Open Access

Pathological transformation of rectal adenocarcinoma to choriocarcinoma in a male patient: A case report and review of the literature

Yefang Lao, Xikai Zhang, Zhongzhong Peng, Xiao Zhou, Xianyuan Miao, Qiongqiong Wang, Sijia Ren, Kaifeng Wang, Hongmin Lu
Article Number: 493
Published online on: 07 September 2026

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Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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