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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2019 Volume 17 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Editorial Open Access

[Editorial] The 2nd Conference of the Romanian Society of Immuno‑Dermatology, Bucharest, September 27-29, 2018

Monica Neagu, Daniel Boda
Pages: 4053-4054
Published online on: 27 February 2019

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Article Open Access

Dendritic cell distribution in mycosis fungoides vs. inflammatory dermatosis and other T-cell skin lymphoma

Mirela Cioplea, Costin Caruntu, Sabina Zurac, Alexandra Bastian, Liana Sticlaru, Alexandra Cioroianu, Daniel Boda, Gheorghita Jugulete, Luciana Nichita, Cristiana Popp
Pages: 4055-4059
Published online on: 01 March 2019

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Review Open Access

Angiogenesis in cutaneous T‑cell lymphoma ‑ proteomic approaches (Review)

Cristiana Tanase, Ionela Daniela Popescu, Ana‑Maria Enciu, Ancuta Augustina Gheorghisan‑Galateanu, Elena Codrici, Simona Mihai, Lucian Albulescu, Laura Necula, Radu Albulescu
Pages: 4060-4067
Published online on: 19 November 2018

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Review Open Access

Inflammation: A key process in skin tumorigenesis (Review)

Monica Neagu, Carolina Constantin, Constantin Caruntu, Carmen Dumitru, Mihaela Surcel, Sabina Zurac
Pages: 4068-4084
Published online on: 19 November 2018

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Review

Photodynamic therapy: A hot topic in dermato-oncology (Review)

Mircea Tampa, Maria-Isabela Sarbu, Clara Matei, Cristina-Iulia Mitran, Madalina-Irina Mitran, Constantin Caruntu, Carolina Constantin, Monica Neagu, Simona-Roxana Georgescu
Pages: 4085-4093
Published online on: 16 January 2019

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Case Report Open Access

Non-invasive imaging techniques for the in vivo diagnosis of Bowen's disease: Three case reports

Simona Laura Ianoși, Alexandra Batani, Mihaela Adriana Ilie, Mircea Tampa, Simona-Roxana Georgescu, Sabina Zurac, Daniel Boda, Nicolae Gabriel Ianosi, Daniela Neagoe, Daniela Calina, Cristina Tutunaru, Caruntu Constantin
Pages: 4094-4101
Published online on: 27 February 2019

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Review Open Access

Current and future applications of confocal laser scanning microscopy imaging in skin oncology (Review)

Mihaela Adriana Ilie, Constantin Caruntu, Mihai Lupu, Daniela Lixandru, Mircea Tampa, Simona-Roxana Georgescu, Alexandra Bastian, Carolina Constantin, Monica Neagu, Sabina Andrada Zurac, Daniel Boda
Pages: 4102-4111
Published online on: 25 February 2019

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Review Open Access

Vascular patterns in basal cell carcinoma: Dermoscopic, confocal and histopathological perspectives (Review)

Mihai Lupu, Constantin Caruntu, Maria Iris Popa, Vlad Mihai Voiculescu, Sabina Zurac, Daniel Boda
Pages: 4112-4125
Published online on: 25 February 2019

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Review Open Access

The 1, 2, 3, 4 of carcinoid heart disease: Comprehensive cardiovascular imaging is the mainstay of complex surgical treatment (Review)

Dinu Valentin Balanescu, Teodora Donisan, Juan Lopez-Mattei, Saamir Hassan, Peter Kim, Arvind Dasari, Daniel Halperin, James Yao, Biswajit Kar, Igor Gregoric, Serban Mihai Balanescu, Cezar Iliescu
Pages: 4126-4132
Published online on: 19 November 2018

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Review Open Access

Acanthosis nigricans: To be or not to be afraid (Review)

Maria-Linda Popa, Adrian Claudiu Popa, Cristiana Tanase, Ancuta-Augustina Gheorghisan-Galateanu
Pages: 4133-4138
Published online on: 19 November 2018

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Article Open Access

Risk factors for melanoma and skin health behaviour:An analysis on Romanian melanoma patients

Oana Fechete, Loredana Ungureanu, Simona Șenilă, Daniela Vornicescu, Sorina Dănescu, Alina Vasilovici, Elisabeta Candrea, Ștefan Cristian Vesa, Rodica Cosgarea
Pages: 4139-4144
Published online on: 19 November 2018

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Article

A 10-year retrospective study of melanoma stage at diagnosis in the academic emergency hospital of Sibiu county

Maria Rotaru, Cristina Raluca Jitian, Gabriela Mariana Iancu
Pages: 4145-4148
Published online on: 01 March 2019

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Article Open Access

Comparative analysis of CEACAM1 expression in thin melanomas with and without regression

Luciana Nichita, Sabina Zurac, Alexandra Bastian, Patricia Stinga, Roxana Nedelcu, Alice Brinzea, Gabriela Turcu, Daniela Ion, Lucia Jilaveanu, Liana Sticlaru, Cristiana Popp, Mirela Cioplea
Pages: 4149-4154
Published online on: 25 February 2019

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Review

Tumor infiltrating lymphocytes: The regulator of melanoma evolution (Review)

Mihaela Antohe, Roxana Ioana Nedelcu, Luciana Nichita, Cristiana Gabriela Popp, Mirela Cioplea, Alice Brinzea, Anastasia Hodorogea, Andreea Calinescu, Mihaela Balaban, Daniela Adriana Ion, Carmen Diaconu, Coralia Bleotu, Daniel Pirici, Sabina Andrada Zurac, Gabriela Turcu
Pages: 4155-4161
Published online on: 16 January 2019

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Review Open Access

Vitamin D receptor polymorphisms and melanoma (Review)

Alina F. Vasilovici, Lavinia Elena Grigore, Loredana Ungureanu, Oana Fechete, Elisabeta Candrea, Adrian P. Trifa, Simona Vișan, Simona Șenilă, Rodica Cosgarea
Pages: 4162-4169
Published online on: 19 November 2018

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Review

Molecular and cellular stratagem of brain metastases associated with melanoma (Review)

Ana-Maria Buga, Anca Oana Docea, Carmen Albu, Ramona Denise Malin, Daciana Elena Branisteanu, Gabriel Ianosi, Simona Laura Ianosi, Andrei Iordache, Daniela Calina
Pages: 4170-4175
Published online on: 14 January 2019

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Case Report Open Access

Complete regression of primary melanoma associated with nevi involution under BRAF inhibitors: A case report and review of the literature

Lavinia Elena Grigore, Loredana Ungureanu, Nona Bejinariu, Crina Seceac, Alina Vasilovici, Simona Corina Senila, Elisabeta Candrea, Oana Fechete, Rodica Cosgarea
Pages: 4176-4182
Published online on: 19 November 2018

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Review

Synthesis and physiological implications of melanic pigments (Review)

Minela Aida Maranduca, Daciana Branisteanu, Dragomir Nicolae Serban, Daniel Constantin Branisteanu, Gabriela Stoleriu, Nicuta Manolache, Ionela Lacramioara Serban
Pages: 4183-4187
Published online on: 25 February 2019

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Article Open Access

Development of QSAR machine learning-based models to forecast the effect of substances on malignant melanoma cells

Robert Ancuceanu, Mihaela Dinu, Iana Neaga, Fekete Gyula Laszlo, Daniel Boda
Pages: 4188-4196
Published online on: 25 February 2019

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Article Open Access

Natural killer cell monitoring in cutaneous melanoma - new dynamic biomarker

Gheorghița Isvoranu, Mihaela Surcel, Radu-Ionuț Huică, Adriana Narcisa Munteanu, Ioana Ruxandra Pîrvu, Dan Ciotaru, Carolina Constantin, Ovidiu Bratu, Monica Neagu, Cornel Ursaciuc
Pages: 4197-4206
Published online on: 25 February 2019

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Review

Crucial role of the pentose phosphate pathway in malignant tumors (Review)

Lin Jin, Yanhong Zhou
Pages: 4213-4221
Published online on: 05 March 2019

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Review

Recent advances in the molecular mechanism of sex disparity in hepatocellular carcinoma (Review)

Yanmeng Li, Anjian Xu, Siyu Jia, Jian Huang
Pages: 4222-4228
Published online on: 08 March 2019

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Article Open Access

Effects of tumor size on prognosis in differentiated thyroid carcinoma smaller than 2 cm

Ting‑Ting Zhang, Cun‑Fu Li, Shi‑Shuai Wen, Dong‑Zhe Huang, Guo‑Hua Sun, Yong‑Xue Zhu, Yu Wang, Qing‑Hai Ji, Ning Qu, Rong‑Liang Shi
Pages: 4229-4236
Published online on: 28 February 2019

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Article Open Access

Pharmacokinetic analysis for the differentiation of pituitary microadenoma subtypes through dynamic contrast‑enhanced magnetic resonance imaging

Jian Zhai, Wenqiang Zheng, Qin Zhang, Jiangfen Wu, Xuexi Zhang
Pages: 4237-4244
Published online on: 28 February 2019

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Article Open Access

A four‑gene signature for prognosis in breast cancer patients with hypermethylated IL15RA

Hui Yang, Li Zhou, Jianhua Chen, Jiang Su, Wei Shen, Biao Liu, Jundong Zhou, Shiyou Yu, Jun Qian
Pages: 4245-4254
Published online on: 12 March 2019

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Article Open Access

Sodium orthovanadate inhibits growth and triggers apoptosis of human anaplastic thyroid carcinoma cells in vitro and in vivo

Qingan Yu, Wenjing Jiang, Dan Li, Mingqi Gu, Kunpeng Liu, Liqian Dong, Chaoqun Wang, Hongchi Jiang, Wenjie Dai
Pages: 4255-4262
Published online on: 28 February 2019

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Article Open Access

Knockdown of ISOC1 suppresses cell proliferation in pancreatic cancer in vitro

Li Cheng, Yan Zhao, Maochun Tang, Zhengsheng Luo, Xingpeng Wang
Pages: 4263-4270
Published online on: 28 February 2019

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Article Open Access

Diagnostic efficacy of PET/CT in bone tumors

Songhui Han, Yanzhou Li, Yuejing Li, Min Zhao
Pages: 4271-4276
Published online on: 04 March 2019

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Article Open Access

Combination of metformin and paclitaxel suppresses proliferation and induces apoptosis of human prostate cancer cells via oxidative stress and targeting the mitochondria‑dependent pathway

Yuwan Zhao, Xin Zeng, Huancheng Tang, Dongcai Ye, Jianjun Liu
Pages: 4277-4284
Published online on: 06 March 2019

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Article Open Access

Effect of asiatic acid on epithelial‑mesenchymal transition of human alveolar epithelium A549 cells induced by TGF‑β1

Qingrong Cui, Juan Ren, Qingwei Zhou, Qinmei Yang, Bin Li
Pages: 4285-4292
Published online on: 12 March 2019

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Article Open Access

Diagnostic value analysis of combined detection of Trx, CYFRA21-1 and SCCA in lung cancer

Tao Qu, Jingwen Zhang, Ning Xu, Bo Liu, Meixiang Li, Ailing Liu, Aijun Li, Huaping Tang
Pages: 4293-4298
Published online on: 26 February 2019

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Article Open Access

Effect of miR-200c on proliferation, invasion and apoptosis of prostate cancer LNCaP cells

Jianxi Lin, Yi Lu, Xiao Zhang, Qiwang Mo, Ling Yu
Pages: 4299-4304
Published online on: 04 March 2019

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Article Open Access

Angiographic evaluation of the internal iliac artery branch in pelvic tumour patients: Diagnostic performance of multislice computed tomography angiography

Lin Li, Ketong Wu, Yang Liu, Haiyang Lai, Zhaofei Zeng, Bo Zhang
Pages: 4305-4312
Published online on: 28 February 2019

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Article Open Access

Suppressor gene GRHL1 is associated with prognosis in patients with oesophageal squamous cell carcinoma

Mengyan Li, Zhuo Li, Xinyuan Guan, Yanru Qin
Pages: 4313-4320
Published online on: 25 February 2019

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Article Open Access

Identification of key genes involved in the metastasis of clear cell renal cell carcinoma

Wenhao Wei, Yufeng Lv, Zuhuan Gan, Yanxian Zhang, Xueqiong Han, Zihai Xu
Pages: 4321-4328
Published online on: 08 March 2019

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Article Open Access

AMP‑activated protein kinase α1 serves a carcinogenic role via regulation of vascular endothelial growth factor expression in patients with non‑small cell lung cancer

Gong Dao Hui, Wang Yu Xiu, Chen Yong, Chi Bei Yuan, Zhang Jun, Gu Jian Jun, Yang Jun Jun, Xu Xing Xiang, Hu Su Wei, Min Ling Feng
Pages: 4329-4334
Published online on: 08 March 2019

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Article Open Access

Correlation of OGR1 with proliferation and apoptosis of breast cancer cells

Jianguo Zhang, Lei Che, Wenkai Sun, Jian Shang, Min Hao, Mengzi Tian
Pages: 4335-4340
Published online on: 06 March 2019

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Article Open Access

Differential expression profiles of the transcriptome in bone marrow‑derived cells in lung cancer revealed by next generation sequencing and bioinformatics

Wei‑An Chang, Ying‑Ming Tsai, Yu‑Chen Tsai, Cheng‑Ying Wu, Kuo‑Feng Chang, Chi‑Tun Lien, Jen‑Yu Hung, Ya‑Ling Hsu, Po‑Lin Kuo
Pages: 4341-4350
Published online on: 28 February 2019

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Article

Upregulated forkhead‑box A3 elevates the expression of forkhead‑box A1 and forkhead‑box A2 to promote metastasis in esophageal cancer

Bing Chen, Jiegen Yu, Linming Lu, Fangyuan Dong, Fangfang Zhou, Xiangxiang Tao, Entao Sun
Pages: 4351-4360
Published online on: 26 February 2019

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Article

Demethylation of the HACE1 gene promoter inhibits the proliferation of human liver cancer cells

Zhijun Yu, Yinyin Li, Tao Han, Zhaozhe Liu
Pages: 4361-4368
Published online on: 12 March 2019

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Article Open Access

Construction of lncRNA-mediated ceRNA network to reveal clinically relevant lncRNA biomarkers in glioblastomas

Xiang-Yang Zan, Luo Li
Pages: 4369-4374
Published online on: 05 March 2019

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Article Open Access

Identifying the optimal target genes associated with multiple myeloma by a novel bioinformatical analysis

Yan Xue, Hongmiao Liu, Guangchen Nie, Jing Zhang
Pages: 4375-4382
Published online on: 04 March 2019

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Article Open Access

Clinical significance of BRCA1 and BRCA2 mRNA and protein expression in patients with sporadic gastric cancer

Hee Sung Kim, In Gyu Hwang, Hye Young Min, Yung‑Jue Bang, Woo Ho Kim
Pages: 4383-4392
Published online on: 08 March 2019

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Article Open Access

Knockdown of cell division cycle‑associated protein 4 expression inhibits proliferation of triple negative breast cancer MDA‑MB‑231 cells in vitro and in vivo

Sen Pang, Yuju Xu, Jun Chen, Guibin Li, Jingle Huang, Xianghua Wu
Pages: 4393-4400
Published online on: 26 February 2019

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Article Open Access

High expression of TRIM36 is associated with radiosensitivity in gastric cancer

Zhongsong Man, Tao Chen, Zhongwei Zhu, Haitao Zhang, Lei Ao, Liting Xi, Jin Zhou, Zaixiang Tang
Pages: 4401-4408
Published online on: 07 March 2019

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Article Open Access

RANBP9 suppresses tumor proliferation in colorectal cancer

Chunzhi Qin, Qin Zhang, Guangbin Wu
Pages: 4409-4416
Published online on: 08 March 2019

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Article Open Access

Expression of miR‑26b in ovarian carcinoma tissues and its correlation with clinicopathology

Jianjun Lu, Wei Zhang, Yang Ding, Xiang Li, Jiandong Song
Pages: 4417-4422
Published online on: 05 March 2019

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Article Open Access

Efficacy and association analysis of high‑dose methotrexate in the treatment of children with acute lymphoblastic leukemia

Fangwei Gong, Qingjun Meng, Chengjuan Liu, Yeqi Zhao
Pages: 4423-4428
Published online on: 08 March 2019

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Article Open Access

5‑Fluorouracil‑based adjuvant chemotherapy improves the clinical outcomes of patients with lymphovascular invasion of upper urinary tract cancer and low expression of dihydropyrimidine dehydrogenase

Takahiro Narimatsu, Tsunehito Kambara, Hideyuki Abe, Toshitaka Uematsu, Yuumi Tokura, Issei Suzuki, Kazumasa Sakamoto, Kouhei Takei, Daisaku Nishihara, Gaku Nakamura, Hidetoshi Kokubun, Hideo Yuki, Hironori Betsunoh, Takao Kamai
Pages: 4429-4436
Published online on: 28 February 2019

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Article Open Access

Expression of miR‑490‑5p, miR‑148a‑3p and miR‑608 in bladder cancer and their effects on the biological characteristics of bladder cancer cells

Min Xiang, Wuxiong Yuan, Weiwei Zhang, Jie Huang
Pages: 4437-4442
Published online on: 12 March 2019

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Article Open Access

Application of sevoflurane inhalation combined with epidural anesthesia in patients with colorectal cancer and its effect on postoperative perceptual function

Xiaomin Zhang, Hao Jiang
Pages: 4443-4448
Published online on: 26 February 2019

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Article Open Access

Effect of submucosal injection of normal saline and glycerol fructose on endoscopic polypectomy in patients with colorectal polyps

Haowen Wang, Shuangshuang Wang
Pages: 4449-4454
Published online on: 06 March 2019

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Article Open Access

Cyclin A is a reliable proliferation marker in endometrial cancer cell lines

Kayo Horie, Hayate Yamamoto, Kouhei Karube, Kai Takebayashi, Hironori Yoshino, Haruhiko Yoshioka, Jun Watanabe
Pages: 4455-4462
Published online on: 08 March 2019

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Article Open Access

Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer Retraction in /10.3892/ol.2025.15388

Su‑Liang Li, Na An, Bing Liu, Sheng‑Yu Wang, Jian‑Jun Wang, Yun Ye
Pages: 4463-4473
Published online on: 05 March 2019

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Article Open Access

Five‑long non‑coding RNA risk score system for the effective prediction of gastric cancer patient survival

Zunqi Hu, Dejun Yang, Yuan Tang, Xin Zhang, Ziran Wei, Hongbing Fu, Jiapeng Xu, Zhenxin Zhu, Qingping Cai
Pages: 4474-4486
Published online on: 08 March 2019

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Article Open Access

c‑Myc maintains the self‑renewal and chemoresistance properties of colon cancer stem cells

Huan‑Le Zhang, Ping Wang, Miao‑Zhen Lu, San‑Dian Zhang, Lu Zheng
Pages: 4487-4493
Published online on: 28 February 2019

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Article Open Access

Candidate genes and potential mechanisms for chemoradiotherapy sensitivity in locally advanced rectal cancer

Chunsheng Li, Changyong E, Yangyang Zhou, Wei Yu
Pages: 4494-4504
Published online on: 28 February 2019

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Article Open Access

Polydatin inhibits hepatocellular carcinoma via the AKT/STAT3‑FOXO1 signaling pathway Corrigendum in /10.3892/ol.2019.10856

Jian Jiang, Yaodong Chen, Tianxiu Dong, Minlu Yue, Yu Zhang, Tingting An, Jiuwei Zhang, Pengfei Liu, Xiuhua Yang
Pages: 4505-4513
Published online on: 07 March 2019

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Article Open Access

Metadherin overexpression in perihilar cholangiocarcinoma is associated with lymph node metastasis and poor prognosis

Yan‑Zhi Zhu, Ke Zhou, Lin‑Lin Ruan, Fu Sun, Gen Wang, Wen‑Fang Li
Pages: 4514-4520
Published online on: 12 March 2019

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Article Open Access

Cytokines secreted by human Wharton's jelly stem cells inhibit the proliferation of ovarian cancer (OVCAR3) cells in vitro

Gauthaman Kalamegam, Khalid Hussein Wali Sait, Nisreen Anfinan, Roaa Kadam, Farid Ahmed, Mahmood Rasool, Mohammad Imran Naseer, Peter Natesan Pushparaj, Mohammed Al‑Qahtani
Pages: 4521-4531
Published online on: 01 March 2019

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Label‑free microfluidic chip for the identification of mesothelial cell clusters in pleural effusion

Lili Zhao, Meng Zhao, Yu Yang, Yajun Gu, Fang Zheng, Xuan Wang, Zhiyuan Zheng, Xuguo Sun
Pages: 4532-4544
Published online on: 06 March 2019

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Value of differential diagnosis of contrast‑enhanced ultrasound in benign and malignant thyroid nodules with microcalcification

Zhixiang Gao, Qin Lu, Jiping Yan
Pages: 4545-4549
Published online on: 04 March 2019

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Expression of LDH and CEA in serum in the process of targeted therapy of lung adenocarcinoma and the association between them and prognosis

Guangsi He, Zonghui Jiang, Song Xue, Xiaoyan Sun, Weifei Wang
Pages: 4550-4556
Published online on: 05 March 2019

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Stromal tumor‑infiltrating lymphocytes evaluated on H&E‑stained slides are an independent prognostic factor in epithelial ovarian cancer and ovarian serous carcinoma

Chungsu Hwang, So Jung Lee, Jung Hee Lee, Ki Hyung Kim, Dong Soo Suh, Byung‑Su Kwon, Kyung Un Choi
Pages: 4557-4565
Published online on: 01 March 2019

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The potential role of miR‑126, miR‑21 and miR‑10b as prognostic biomarkers in renal cell carcinoma

Jessica Carlsson, Jesper Christiansen, Sabina Davidsson, Francesca Giunchi, Michelangelo Fiorentino, Pernilla Sundqvist
Pages: 4566-4574
Published online on: 12 March 2019

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Expression of p53 and PTEN in human primary endometrial carcinomas: Clinicopathological and immunohistochemical analysis and study of their concomitant expression

Aggelis Stavropoulos, Michail Varras, Thivi Vasilakaki, Viktoria‑Konstantina Varra, Aikaterini Tsavari, Fani‑Niki Varra, Aphrodite Nonni, Nikolaos Kavantzas, Andreas C. Lazaris
Pages: 4575-4589
Published online on: 01 March 2019

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Influence of obesity on surgical complications of patients with ovarian tumors

Huimin Lv, Suhui Wu
Pages: 4590-4594
Published online on: 04 March 2019

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Correlation of miR-425-5p and IL-23 with pancreatic cancer

Yanmin Lu, Xinqing Wu, Jinxiang Wang
Pages: 4595-4599
Published online on: 04 March 2019

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Distinctive clinicopathological features of Von Hippel‑Lindau‑associated hereditary renal cell carcinoma: A single‑institution study

Baoan Hong, Zhongyuan Zhang, Jingcheng Zhou, Kaifang Ma, Jiufeng Zhang, Lin Cai, Ning Zhang, Kan Gong
Pages: 4600-4606
Published online on: 01 March 2019

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Interleukin‑8 promotes prostate cancer bone metastasis through upregulation of bone sialoprotein

Baohao Liu, Meng Xu, Zhongqing Guo, Jiajie Liu, Xu Chu, Huamao Jiang
Pages: 4607-4613
Published online on: 12 March 2019

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Evaluation of the prognostic significances of γ‑secretase genes in pancreatic cancer

Yun Ho Jeon, Mihyang Ha, Sung Won Kim, Mun Ju Kim, Chi‑Seung Lee, Chang‑Kyu Oh, Myoung‑Eun Han, Sae‑Ock Oh, Yun Hak Kim
Pages: 4614-4620
Published online on: 05 March 2019

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Expression of CLDN6 in tissues of gastric cancer patients: Association with clinical pathology and prognosis

Fangmei Gao, Mingdong Li, Rui Xiang, Xin Zhou, Lianying Zhu, Yi Zhai
Pages: 4621-4625
Published online on: 08 March 2019

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Expression and clinical significance of SLP-2 in ovarian tumors

Jingjing Zhang, Xiucai Song, Cuihong Li, Yanjie Tian
Pages: 4626-4632
Published online on: 05 March 2019

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Linc‑pint inhibits early stage pancreatic ductal adenocarcinoma growth through TGF‑β pathway activation

Huimin Lu, Dujiang Yang, Ling Zhang, Shan Lu, Jun Ye, Mao Li, Weiming Hu
Pages: 4633-4639
Published online on: 05 March 2019

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Article

Overexpression of malignant brain tumor domain containing protein 1 predicts a poor prognosis of prostate cancer

Wanhua Wu, Shoumin Bai, Dingjun Zhu, Kaiwen Li, Wen Dong, Wang He, Shengmeng Peng, Yiming Lai, Qiong Wang, Zhenghui Guo, Leyuan Liu, Hai Huang
Pages: 4640-4646
Published online on: 05 March 2019

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Article

The stem cell‑specific intermediate filament nestin missense variation p.A1199P is associated with pancreatic cancer

Yoko Matsuda, Masashi Tanaka, Motoji Sawabe, Seijiro Mori, Masaaki Muramatsu, Makiko Naka Mieno, Toshiyuki Ishiwata, Tomio Arai
Pages: 4647-4654
Published online on: 04 March 2019

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Article

IL‑32 expression indicates unfavorable prognosis in patients with colon cancer

Jing‑Ming Zhai, Yan‑Hui An, Wei Wang, Yong‑Gang Fan, Guo‑Liang Yao
Pages: 4655-4660
Published online on: 12 March 2019

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Article

Comparison of diagnostic methods for the detection of a BRAF mutation in papillary thyroid cancer

Jingzhu Zhao, Pengpeng Liu, Yang Yu, Jingtai Zhi, Xiangqian Zheng, Jinpu Yu, Ming Gao
Pages: 4661-4666
Published online on: 08 March 2019

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Article

TNFAIP8 promotes cisplatin resistance in cervical carcinoma cells by inhibiting cellular apoptosis

Suxia Wu, Weihua Li, Zhenghui Wu, Tianran Cheng, Ping Wang, Na Li, Xiaonan Liang, Mengmeng Chi, Shuman Zhang, Yuanfang Ma, Yanyun Li, Lihui Chai
Pages: 4667-4674
Published online on: 26 February 2019

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Article

Aspirin inhibits colon cancer cell line migration through regulating epithelial‑mesenchymal transition via Wnt signaling

Shenghang Jin, Xianguo Wu
Pages: 4675-4682
Published online on: 28 February 2019

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Article

Identification of key pathways and genes in nasopharyngeal carcinoma using bioinformatics analysis

Hong‑Ming Zhu, Qian Fei, Lu‑Xi Qian, Bao‑Ling Liu, Xia He, Li Yin
Pages: 4683-4694
Published online on: 08 March 2019

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Article

Investigation of the clonal origin of multifocal papillary thyroid carcinoma according to the X‑chromosome inactivation pattern

Dan Chen, Wenjing Qi, Suling Xie, Lu Feng, Junying Wang, Lifen Wang, Hongwei Guan
Pages: 4695-4700
Published online on: 04 March 2019

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Article

Randomized controlled trial of lobaplatin plus etoposide vs. cisplatin plus etoposide as first‑line therapy in patients with extensive‑stage small cell lung cancer

Ying Cheng, Yun Fan, Xiaoqing Liu, Yunpeng Liu, Jiwei Liu, Dong Wang, Yan Yu, Shukui Qin, Wei Liu, Cheng Huang, Helong Zhang, Jun Liang, Jianhua Shi, Lijun Sheng, Hao Yu
Pages: 4701-4709
Published online on: 08 March 2019

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Article

L‑Lactate dehydrogenase B may be a predictive marker for sensitivity to anti‑EGFR monoclonal antibodies in colorectal cancer cell lines

Ayumu Nagamine, Takuya Araki, Daisuke Nagano, Mitsue Miyazaki, Koujirou Yamamoto
Pages: 4710-4716
Published online on: 26 February 2019

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Article

Clinical effect of postoperative chemoradiotherapy in resected advanced laryngeal squamous cell carcinoma

Ming Zhang, Weiye Deng, Hongli Gong, Cai Li, Yifan Wang, Xiangyu Liu, Lei Tao, Liang Zhou
Pages: 4717-4725
Published online on: 04 March 2019

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Article

Association between TP53 genetic polymorphisms and the methylation and expression of miR‑34a, 34b/c in colorectal cancer tissues

Hak Hoon Jun, Kyubum Kwack, Keun Hee Lee, Jung Oh Kim, Han Sung Park, Chang Soo Ryu, Jeong Yong Lee, Daeun Ko, Jong Woo Kim, Nam Keun Kim
Pages: 4726-4734
Published online on: 01 March 2019

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Article

Discovery of LDD‑1075 as a potent FLT3 inhibitor

Kyoung Bin Yoon, Hyo Jeong Lee, Hye Jin Chung, Jungeun Lee, Jungil Choi, Jeong Doo Heo, Yong‑Chul Kim, Sun‑Young Han
Pages: 4735-4741
Published online on: 01 March 2019

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Retraction Open Access

[Retracted] Aspirin inhibits growth of ovarian cancer by upregulating caspase-3 and downregulating bcl-2

Lin Li, Xiaogang Mao, Xiaomin Qin, Min Zhou, Hui Xing, Fan Dong, Xiaoyuan Jiang, Wenhui Zhuang
Pages: 4742-4742
Published online on: 04 March 2019

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June-2026 Volume 31 Issue 6

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Review
Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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Journal Cover
July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Article Open Access

Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Article Open Access

Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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Article Open Access

D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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