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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2019 Volume 17 Issue 5

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Editorial Open Access

[Editorial] The 2nd Conference of the Romanian Society of Immuno‑Dermatology, Bucharest, September 27-29, 2018

Monica Neagu, Daniel Boda
Pages: 4053-4054
Published online on: 27 February 2019

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Article Open Access

Dendritic cell distribution in mycosis fungoides vs. inflammatory dermatosis and other T-cell skin lymphoma

Mirela Cioplea, Costin Caruntu, Sabina Zurac, Alexandra Bastian, Liana Sticlaru, Alexandra Cioroianu, Daniel Boda, Gheorghita Jugulete, Luciana Nichita, Cristiana Popp
Pages: 4055-4059
Published online on: 01 March 2019

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Review Open Access

Angiogenesis in cutaneous T‑cell lymphoma ‑ proteomic approaches (Review)

Cristiana Tanase, Ionela Daniela Popescu, Ana‑Maria Enciu, Ancuta Augustina Gheorghisan‑Galateanu, Elena Codrici, Simona Mihai, Lucian Albulescu, Laura Necula, Radu Albulescu
Pages: 4060-4067
Published online on: 19 November 2018

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Review Open Access

Inflammation: A key process in skin tumorigenesis (Review)

Monica Neagu, Carolina Constantin, Constantin Caruntu, Carmen Dumitru, Mihaela Surcel, Sabina Zurac
Pages: 4068-4084
Published online on: 19 November 2018

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Review

Photodynamic therapy: A hot topic in dermato-oncology (Review)

Mircea Tampa, Maria-Isabela Sarbu, Clara Matei, Cristina-Iulia Mitran, Madalina-Irina Mitran, Constantin Caruntu, Carolina Constantin, Monica Neagu, Simona-Roxana Georgescu
Pages: 4085-4093
Published online on: 16 January 2019

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Case Report Open Access

Non-invasive imaging techniques for the in vivo diagnosis of Bowen's disease: Three case reports

Simona Laura Ianoși, Alexandra Batani, Mihaela Adriana Ilie, Mircea Tampa, Simona-Roxana Georgescu, Sabina Zurac, Daniel Boda, Nicolae Gabriel Ianosi, Daniela Neagoe, Daniela Calina, Cristina Tutunaru, Caruntu Constantin
Pages: 4094-4101
Published online on: 27 February 2019

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Review Open Access

Current and future applications of confocal laser scanning microscopy imaging in skin oncology (Review)

Mihaela Adriana Ilie, Constantin Caruntu, Mihai Lupu, Daniela Lixandru, Mircea Tampa, Simona-Roxana Georgescu, Alexandra Bastian, Carolina Constantin, Monica Neagu, Sabina Andrada Zurac, Daniel Boda
Pages: 4102-4111
Published online on: 25 February 2019

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Review Open Access

Vascular patterns in basal cell carcinoma: Dermoscopic, confocal and histopathological perspectives (Review)

Mihai Lupu, Constantin Caruntu, Maria Iris Popa, Vlad Mihai Voiculescu, Sabina Zurac, Daniel Boda
Pages: 4112-4125
Published online on: 25 February 2019

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Review Open Access

The 1, 2, 3, 4 of carcinoid heart disease: Comprehensive cardiovascular imaging is the mainstay of complex surgical treatment (Review)

Dinu Valentin Balanescu, Teodora Donisan, Juan Lopez-Mattei, Saamir Hassan, Peter Kim, Arvind Dasari, Daniel Halperin, James Yao, Biswajit Kar, Igor Gregoric, Serban Mihai Balanescu, Cezar Iliescu
Pages: 4126-4132
Published online on: 19 November 2018

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Review Open Access

Acanthosis nigricans: To be or not to be afraid (Review)

Maria-Linda Popa, Adrian Claudiu Popa, Cristiana Tanase, Ancuta-Augustina Gheorghisan-Galateanu
Pages: 4133-4138
Published online on: 19 November 2018

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Article Open Access

Risk factors for melanoma and skin health behaviour:An analysis on Romanian melanoma patients

Oana Fechete, Loredana Ungureanu, Simona Șenilă, Daniela Vornicescu, Sorina Dănescu, Alina Vasilovici, Elisabeta Candrea, Ștefan Cristian Vesa, Rodica Cosgarea
Pages: 4139-4144
Published online on: 19 November 2018

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Article

A 10-year retrospective study of melanoma stage at diagnosis in the academic emergency hospital of Sibiu county

Maria Rotaru, Cristina Raluca Jitian, Gabriela Mariana Iancu
Pages: 4145-4148
Published online on: 01 March 2019

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Article Open Access

Comparative analysis of CEACAM1 expression in thin melanomas with and without regression

Luciana Nichita, Sabina Zurac, Alexandra Bastian, Patricia Stinga, Roxana Nedelcu, Alice Brinzea, Gabriela Turcu, Daniela Ion, Lucia Jilaveanu, Liana Sticlaru, Cristiana Popp, Mirela Cioplea
Pages: 4149-4154
Published online on: 25 February 2019

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Review

Tumor infiltrating lymphocytes: The regulator of melanoma evolution (Review)

Mihaela Antohe, Roxana Ioana Nedelcu, Luciana Nichita, Cristiana Gabriela Popp, Mirela Cioplea, Alice Brinzea, Anastasia Hodorogea, Andreea Calinescu, Mihaela Balaban, Daniela Adriana Ion, Carmen Diaconu, Coralia Bleotu, Daniel Pirici, Sabina Andrada Zurac, Gabriela Turcu
Pages: 4155-4161
Published online on: 16 January 2019

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Review Open Access

Vitamin D receptor polymorphisms and melanoma (Review)

Alina F. Vasilovici, Lavinia Elena Grigore, Loredana Ungureanu, Oana Fechete, Elisabeta Candrea, Adrian P. Trifa, Simona Vișan, Simona Șenilă, Rodica Cosgarea
Pages: 4162-4169
Published online on: 19 November 2018

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Review

Molecular and cellular stratagem of brain metastases associated with melanoma (Review)

Ana-Maria Buga, Anca Oana Docea, Carmen Albu, Ramona Denise Malin, Daciana Elena Branisteanu, Gabriel Ianosi, Simona Laura Ianosi, Andrei Iordache, Daniela Calina
Pages: 4170-4175
Published online on: 14 January 2019

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Case Report Open Access

Complete regression of primary melanoma associated with nevi involution under BRAF inhibitors: A case report and review of the literature

Lavinia Elena Grigore, Loredana Ungureanu, Nona Bejinariu, Crina Seceac, Alina Vasilovici, Simona Corina Senila, Elisabeta Candrea, Oana Fechete, Rodica Cosgarea
Pages: 4176-4182
Published online on: 19 November 2018

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Review

Synthesis and physiological implications of melanic pigments (Review)

Minela Aida Maranduca, Daciana Branisteanu, Dragomir Nicolae Serban, Daniel Constantin Branisteanu, Gabriela Stoleriu, Nicuta Manolache, Ionela Lacramioara Serban
Pages: 4183-4187
Published online on: 25 February 2019

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Article Open Access

Development of QSAR machine learning-based models to forecast the effect of substances on malignant melanoma cells

Robert Ancuceanu, Mihaela Dinu, Iana Neaga, Fekete Gyula Laszlo, Daniel Boda
Pages: 4188-4196
Published online on: 25 February 2019

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Article Open Access

Natural killer cell monitoring in cutaneous melanoma - new dynamic biomarker

Gheorghița Isvoranu, Mihaela Surcel, Radu-Ionuț Huică, Adriana Narcisa Munteanu, Ioana Ruxandra Pîrvu, Dan Ciotaru, Carolina Constantin, Ovidiu Bratu, Monica Neagu, Cornel Ursaciuc
Pages: 4197-4206
Published online on: 25 February 2019

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Review

Crucial role of the pentose phosphate pathway in malignant tumors (Review)

Lin Jin, Yanhong Zhou
Pages: 4213-4221
Published online on: 05 March 2019

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Review

Recent advances in the molecular mechanism of sex disparity in hepatocellular carcinoma (Review)

Yanmeng Li, Anjian Xu, Siyu Jia, Jian Huang
Pages: 4222-4228
Published online on: 08 March 2019

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Article Open Access

Effects of tumor size on prognosis in differentiated thyroid carcinoma smaller than 2 cm

Ting‑Ting Zhang, Cun‑Fu Li, Shi‑Shuai Wen, Dong‑Zhe Huang, Guo‑Hua Sun, Yong‑Xue Zhu, Yu Wang, Qing‑Hai Ji, Ning Qu, Rong‑Liang Shi
Pages: 4229-4236
Published online on: 28 February 2019

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Article Open Access

Pharmacokinetic analysis for the differentiation of pituitary microadenoma subtypes through dynamic contrast‑enhanced magnetic resonance imaging

Jian Zhai, Wenqiang Zheng, Qin Zhang, Jiangfen Wu, Xuexi Zhang
Pages: 4237-4244
Published online on: 28 February 2019

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Article Open Access

A four‑gene signature for prognosis in breast cancer patients with hypermethylated IL15RA

Hui Yang, Li Zhou, Jianhua Chen, Jiang Su, Wei Shen, Biao Liu, Jundong Zhou, Shiyou Yu, Jun Qian
Pages: 4245-4254
Published online on: 12 March 2019

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Article Open Access

Sodium orthovanadate inhibits growth and triggers apoptosis of human anaplastic thyroid carcinoma cells in vitro and in vivo

Qingan Yu, Wenjing Jiang, Dan Li, Mingqi Gu, Kunpeng Liu, Liqian Dong, Chaoqun Wang, Hongchi Jiang, Wenjie Dai
Pages: 4255-4262
Published online on: 28 February 2019

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Article Open Access

Knockdown of ISOC1 suppresses cell proliferation in pancreatic cancer in vitro

Li Cheng, Yan Zhao, Maochun Tang, Zhengsheng Luo, Xingpeng Wang
Pages: 4263-4270
Published online on: 28 February 2019

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Article Open Access

Diagnostic efficacy of PET/CT in bone tumors

Songhui Han, Yanzhou Li, Yuejing Li, Min Zhao
Pages: 4271-4276
Published online on: 04 March 2019

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Article Open Access

Combination of metformin and paclitaxel suppresses proliferation and induces apoptosis of human prostate cancer cells via oxidative stress and targeting the mitochondria‑dependent pathway

Yuwan Zhao, Xin Zeng, Huancheng Tang, Dongcai Ye, Jianjun Liu
Pages: 4277-4284
Published online on: 06 March 2019

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Article Open Access

Effect of asiatic acid on epithelial‑mesenchymal transition of human alveolar epithelium A549 cells induced by TGF‑β1

Qingrong Cui, Juan Ren, Qingwei Zhou, Qinmei Yang, Bin Li
Pages: 4285-4292
Published online on: 12 March 2019

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Article Open Access

Diagnostic value analysis of combined detection of Trx, CYFRA21-1 and SCCA in lung cancer

Tao Qu, Jingwen Zhang, Ning Xu, Bo Liu, Meixiang Li, Ailing Liu, Aijun Li, Huaping Tang
Pages: 4293-4298
Published online on: 26 February 2019

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Article Open Access

Effect of miR-200c on proliferation, invasion and apoptosis of prostate cancer LNCaP cells

Jianxi Lin, Yi Lu, Xiao Zhang, Qiwang Mo, Ling Yu
Pages: 4299-4304
Published online on: 04 March 2019

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Article Open Access

Angiographic evaluation of the internal iliac artery branch in pelvic tumour patients: Diagnostic performance of multislice computed tomography angiography

Lin Li, Ketong Wu, Yang Liu, Haiyang Lai, Zhaofei Zeng, Bo Zhang
Pages: 4305-4312
Published online on: 28 February 2019

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Article Open Access

Suppressor gene GRHL1 is associated with prognosis in patients with oesophageal squamous cell carcinoma

Mengyan Li, Zhuo Li, Xinyuan Guan, Yanru Qin
Pages: 4313-4320
Published online on: 25 February 2019

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Article Open Access

Identification of key genes involved in the metastasis of clear cell renal cell carcinoma

Wenhao Wei, Yufeng Lv, Zuhuan Gan, Yanxian Zhang, Xueqiong Han, Zihai Xu
Pages: 4321-4328
Published online on: 08 March 2019

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Article Open Access

AMP‑activated protein kinase α1 serves a carcinogenic role via regulation of vascular endothelial growth factor expression in patients with non‑small cell lung cancer

Gong Dao Hui, Wang Yu Xiu, Chen Yong, Chi Bei Yuan, Zhang Jun, Gu Jian Jun, Yang Jun Jun, Xu Xing Xiang, Hu Su Wei, Min Ling Feng
Pages: 4329-4334
Published online on: 08 March 2019

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Article Open Access

Correlation of OGR1 with proliferation and apoptosis of breast cancer cells

Jianguo Zhang, Lei Che, Wenkai Sun, Jian Shang, Min Hao, Mengzi Tian
Pages: 4335-4340
Published online on: 06 March 2019

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Article Open Access

Differential expression profiles of the transcriptome in bone marrow‑derived cells in lung cancer revealed by next generation sequencing and bioinformatics

Wei‑An Chang, Ying‑Ming Tsai, Yu‑Chen Tsai, Cheng‑Ying Wu, Kuo‑Feng Chang, Chi‑Tun Lien, Jen‑Yu Hung, Ya‑Ling Hsu, Po‑Lin Kuo
Pages: 4341-4350
Published online on: 28 February 2019

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Article

Upregulated forkhead‑box A3 elevates the expression of forkhead‑box A1 and forkhead‑box A2 to promote metastasis in esophageal cancer

Bing Chen, Jiegen Yu, Linming Lu, Fangyuan Dong, Fangfang Zhou, Xiangxiang Tao, Entao Sun
Pages: 4351-4360
Published online on: 26 February 2019

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Article

Demethylation of the HACE1 gene promoter inhibits the proliferation of human liver cancer cells

Zhijun Yu, Yinyin Li, Tao Han, Zhaozhe Liu
Pages: 4361-4368
Published online on: 12 March 2019

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Article Open Access

Construction of lncRNA-mediated ceRNA network to reveal clinically relevant lncRNA biomarkers in glioblastomas

Xiang-Yang Zan, Luo Li
Pages: 4369-4374
Published online on: 05 March 2019

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Article Open Access

Identifying the optimal target genes associated with multiple myeloma by a novel bioinformatical analysis

Yan Xue, Hongmiao Liu, Guangchen Nie, Jing Zhang
Pages: 4375-4382
Published online on: 04 March 2019

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Article Open Access

Clinical significance of BRCA1 and BRCA2 mRNA and protein expression in patients with sporadic gastric cancer

Hee Sung Kim, In Gyu Hwang, Hye Young Min, Yung‑Jue Bang, Woo Ho Kim
Pages: 4383-4392
Published online on: 08 March 2019

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Article Open Access

Knockdown of cell division cycle‑associated protein 4 expression inhibits proliferation of triple negative breast cancer MDA‑MB‑231 cells in vitro and in vivo

Sen Pang, Yuju Xu, Jun Chen, Guibin Li, Jingle Huang, Xianghua Wu
Pages: 4393-4400
Published online on: 26 February 2019

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Article Open Access

High expression of TRIM36 is associated with radiosensitivity in gastric cancer

Zhongsong Man, Tao Chen, Zhongwei Zhu, Haitao Zhang, Lei Ao, Liting Xi, Jin Zhou, Zaixiang Tang
Pages: 4401-4408
Published online on: 07 March 2019

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Article Open Access

RANBP9 suppresses tumor proliferation in colorectal cancer

Chunzhi Qin, Qin Zhang, Guangbin Wu
Pages: 4409-4416
Published online on: 08 March 2019

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Article Open Access

Expression of miR‑26b in ovarian carcinoma tissues and its correlation with clinicopathology

Jianjun Lu, Wei Zhang, Yang Ding, Xiang Li, Jiandong Song
Pages: 4417-4422
Published online on: 05 March 2019

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Article Open Access

Efficacy and association analysis of high‑dose methotrexate in the treatment of children with acute lymphoblastic leukemia

Fangwei Gong, Qingjun Meng, Chengjuan Liu, Yeqi Zhao
Pages: 4423-4428
Published online on: 08 March 2019

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Article Open Access

5‑Fluorouracil‑based adjuvant chemotherapy improves the clinical outcomes of patients with lymphovascular invasion of upper urinary tract cancer and low expression of dihydropyrimidine dehydrogenase

Takahiro Narimatsu, Tsunehito Kambara, Hideyuki Abe, Toshitaka Uematsu, Yuumi Tokura, Issei Suzuki, Kazumasa Sakamoto, Kouhei Takei, Daisaku Nishihara, Gaku Nakamura, Hidetoshi Kokubun, Hideo Yuki, Hironori Betsunoh, Takao Kamai
Pages: 4429-4436
Published online on: 28 February 2019

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Article Open Access

Expression of miR‑490‑5p, miR‑148a‑3p and miR‑608 in bladder cancer and their effects on the biological characteristics of bladder cancer cells

Min Xiang, Wuxiong Yuan, Weiwei Zhang, Jie Huang
Pages: 4437-4442
Published online on: 12 March 2019

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Article Open Access

Application of sevoflurane inhalation combined with epidural anesthesia in patients with colorectal cancer and its effect on postoperative perceptual function

Xiaomin Zhang, Hao Jiang
Pages: 4443-4448
Published online on: 26 February 2019

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Article Open Access

Effect of submucosal injection of normal saline and glycerol fructose on endoscopic polypectomy in patients with colorectal polyps

Haowen Wang, Shuangshuang Wang
Pages: 4449-4454
Published online on: 06 March 2019

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Article Open Access

Cyclin A is a reliable proliferation marker in endometrial cancer cell lines

Kayo Horie, Hayate Yamamoto, Kouhei Karube, Kai Takebayashi, Hironori Yoshino, Haruhiko Yoshioka, Jun Watanabe
Pages: 4455-4462
Published online on: 08 March 2019

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Article Open Access

Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer Retraction in /10.3892/ol.2025.15388

Su‑Liang Li, Na An, Bing Liu, Sheng‑Yu Wang, Jian‑Jun Wang, Yun Ye
Pages: 4463-4473
Published online on: 05 March 2019

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Article Open Access

Five‑long non‑coding RNA risk score system for the effective prediction of gastric cancer patient survival

Zunqi Hu, Dejun Yang, Yuan Tang, Xin Zhang, Ziran Wei, Hongbing Fu, Jiapeng Xu, Zhenxin Zhu, Qingping Cai
Pages: 4474-4486
Published online on: 08 March 2019

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Article Open Access

c‑Myc maintains the self‑renewal and chemoresistance properties of colon cancer stem cells

Huan‑Le Zhang, Ping Wang, Miao‑Zhen Lu, San‑Dian Zhang, Lu Zheng
Pages: 4487-4493
Published online on: 28 February 2019

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Article Open Access

Candidate genes and potential mechanisms for chemoradiotherapy sensitivity in locally advanced rectal cancer

Chunsheng Li, Changyong E, Yangyang Zhou, Wei Yu
Pages: 4494-4504
Published online on: 28 February 2019

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Article Open Access

Polydatin inhibits hepatocellular carcinoma via the AKT/STAT3‑FOXO1 signaling pathway Corrigendum in /10.3892/ol.2019.10856

Jian Jiang, Yaodong Chen, Tianxiu Dong, Minlu Yue, Yu Zhang, Tingting An, Jiuwei Zhang, Pengfei Liu, Xiuhua Yang
Pages: 4505-4513
Published online on: 07 March 2019

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Article Open Access

Metadherin overexpression in perihilar cholangiocarcinoma is associated with lymph node metastasis and poor prognosis

Yan‑Zhi Zhu, Ke Zhou, Lin‑Lin Ruan, Fu Sun, Gen Wang, Wen‑Fang Li
Pages: 4514-4520
Published online on: 12 March 2019

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Article Open Access

Cytokines secreted by human Wharton's jelly stem cells inhibit the proliferation of ovarian cancer (OVCAR3) cells in vitro

Gauthaman Kalamegam, Khalid Hussein Wali Sait, Nisreen Anfinan, Roaa Kadam, Farid Ahmed, Mahmood Rasool, Mohammad Imran Naseer, Peter Natesan Pushparaj, Mohammed Al‑Qahtani
Pages: 4521-4531
Published online on: 01 March 2019

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Label‑free microfluidic chip for the identification of mesothelial cell clusters in pleural effusion

Lili Zhao, Meng Zhao, Yu Yang, Yajun Gu, Fang Zheng, Xuan Wang, Zhiyuan Zheng, Xuguo Sun
Pages: 4532-4544
Published online on: 06 March 2019

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Value of differential diagnosis of contrast‑enhanced ultrasound in benign and malignant thyroid nodules with microcalcification

Zhixiang Gao, Qin Lu, Jiping Yan
Pages: 4545-4549
Published online on: 04 March 2019

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Expression of LDH and CEA in serum in the process of targeted therapy of lung adenocarcinoma and the association between them and prognosis

Guangsi He, Zonghui Jiang, Song Xue, Xiaoyan Sun, Weifei Wang
Pages: 4550-4556
Published online on: 05 March 2019

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Stromal tumor‑infiltrating lymphocytes evaluated on H&E‑stained slides are an independent prognostic factor in epithelial ovarian cancer and ovarian serous carcinoma

Chungsu Hwang, So Jung Lee, Jung Hee Lee, Ki Hyung Kim, Dong Soo Suh, Byung‑Su Kwon, Kyung Un Choi
Pages: 4557-4565
Published online on: 01 March 2019

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The potential role of miR‑126, miR‑21 and miR‑10b as prognostic biomarkers in renal cell carcinoma

Jessica Carlsson, Jesper Christiansen, Sabina Davidsson, Francesca Giunchi, Michelangelo Fiorentino, Pernilla Sundqvist
Pages: 4566-4574
Published online on: 12 March 2019

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Expression of p53 and PTEN in human primary endometrial carcinomas: Clinicopathological and immunohistochemical analysis and study of their concomitant expression

Aggelis Stavropoulos, Michail Varras, Thivi Vasilakaki, Viktoria‑Konstantina Varra, Aikaterini Tsavari, Fani‑Niki Varra, Aphrodite Nonni, Nikolaos Kavantzas, Andreas C. Lazaris
Pages: 4575-4589
Published online on: 01 March 2019

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Influence of obesity on surgical complications of patients with ovarian tumors

Huimin Lv, Suhui Wu
Pages: 4590-4594
Published online on: 04 March 2019

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Correlation of miR-425-5p and IL-23 with pancreatic cancer

Yanmin Lu, Xinqing Wu, Jinxiang Wang
Pages: 4595-4599
Published online on: 04 March 2019

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Distinctive clinicopathological features of Von Hippel‑Lindau‑associated hereditary renal cell carcinoma: A single‑institution study

Baoan Hong, Zhongyuan Zhang, Jingcheng Zhou, Kaifang Ma, Jiufeng Zhang, Lin Cai, Ning Zhang, Kan Gong
Pages: 4600-4606
Published online on: 01 March 2019

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Interleukin‑8 promotes prostate cancer bone metastasis through upregulation of bone sialoprotein

Baohao Liu, Meng Xu, Zhongqing Guo, Jiajie Liu, Xu Chu, Huamao Jiang
Pages: 4607-4613
Published online on: 12 March 2019

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Evaluation of the prognostic significances of γ‑secretase genes in pancreatic cancer

Yun Ho Jeon, Mihyang Ha, Sung Won Kim, Mun Ju Kim, Chi‑Seung Lee, Chang‑Kyu Oh, Myoung‑Eun Han, Sae‑Ock Oh, Yun Hak Kim
Pages: 4614-4620
Published online on: 05 March 2019

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Expression of CLDN6 in tissues of gastric cancer patients: Association with clinical pathology and prognosis

Fangmei Gao, Mingdong Li, Rui Xiang, Xin Zhou, Lianying Zhu, Yi Zhai
Pages: 4621-4625
Published online on: 08 March 2019

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Expression and clinical significance of SLP-2 in ovarian tumors

Jingjing Zhang, Xiucai Song, Cuihong Li, Yanjie Tian
Pages: 4626-4632
Published online on: 05 March 2019

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Linc‑pint inhibits early stage pancreatic ductal adenocarcinoma growth through TGF‑β pathway activation

Huimin Lu, Dujiang Yang, Ling Zhang, Shan Lu, Jun Ye, Mao Li, Weiming Hu
Pages: 4633-4639
Published online on: 05 March 2019

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Article

Overexpression of malignant brain tumor domain containing protein 1 predicts a poor prognosis of prostate cancer

Wanhua Wu, Shoumin Bai, Dingjun Zhu, Kaiwen Li, Wen Dong, Wang He, Shengmeng Peng, Yiming Lai, Qiong Wang, Zhenghui Guo, Leyuan Liu, Hai Huang
Pages: 4640-4646
Published online on: 05 March 2019

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Article

The stem cell‑specific intermediate filament nestin missense variation p.A1199P is associated with pancreatic cancer

Yoko Matsuda, Masashi Tanaka, Motoji Sawabe, Seijiro Mori, Masaaki Muramatsu, Makiko Naka Mieno, Toshiyuki Ishiwata, Tomio Arai
Pages: 4647-4654
Published online on: 04 March 2019

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Article

IL‑32 expression indicates unfavorable prognosis in patients with colon cancer

Jing‑Ming Zhai, Yan‑Hui An, Wei Wang, Yong‑Gang Fan, Guo‑Liang Yao
Pages: 4655-4660
Published online on: 12 March 2019

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Article

Comparison of diagnostic methods for the detection of a BRAF mutation in papillary thyroid cancer

Jingzhu Zhao, Pengpeng Liu, Yang Yu, Jingtai Zhi, Xiangqian Zheng, Jinpu Yu, Ming Gao
Pages: 4661-4666
Published online on: 08 March 2019

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Article

TNFAIP8 promotes cisplatin resistance in cervical carcinoma cells by inhibiting cellular apoptosis

Suxia Wu, Weihua Li, Zhenghui Wu, Tianran Cheng, Ping Wang, Na Li, Xiaonan Liang, Mengmeng Chi, Shuman Zhang, Yuanfang Ma, Yanyun Li, Lihui Chai
Pages: 4667-4674
Published online on: 26 February 2019

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Article

Aspirin inhibits colon cancer cell line migration through regulating epithelial‑mesenchymal transition via Wnt signaling

Shenghang Jin, Xianguo Wu
Pages: 4675-4682
Published online on: 28 February 2019

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Article

Identification of key pathways and genes in nasopharyngeal carcinoma using bioinformatics analysis

Hong‑Ming Zhu, Qian Fei, Lu‑Xi Qian, Bao‑Ling Liu, Xia He, Li Yin
Pages: 4683-4694
Published online on: 08 March 2019

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Article

Investigation of the clonal origin of multifocal papillary thyroid carcinoma according to the X‑chromosome inactivation pattern

Dan Chen, Wenjing Qi, Suling Xie, Lu Feng, Junying Wang, Lifen Wang, Hongwei Guan
Pages: 4695-4700
Published online on: 04 March 2019

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Article

Randomized controlled trial of lobaplatin plus etoposide vs. cisplatin plus etoposide as first‑line therapy in patients with extensive‑stage small cell lung cancer

Ying Cheng, Yun Fan, Xiaoqing Liu, Yunpeng Liu, Jiwei Liu, Dong Wang, Yan Yu, Shukui Qin, Wei Liu, Cheng Huang, Helong Zhang, Jun Liang, Jianhua Shi, Lijun Sheng, Hao Yu
Pages: 4701-4709
Published online on: 08 March 2019

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Article

L‑Lactate dehydrogenase B may be a predictive marker for sensitivity to anti‑EGFR monoclonal antibodies in colorectal cancer cell lines

Ayumu Nagamine, Takuya Araki, Daisuke Nagano, Mitsue Miyazaki, Koujirou Yamamoto
Pages: 4710-4716
Published online on: 26 February 2019

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Article

Clinical effect of postoperative chemoradiotherapy in resected advanced laryngeal squamous cell carcinoma

Ming Zhang, Weiye Deng, Hongli Gong, Cai Li, Yifan Wang, Xiangyu Liu, Lei Tao, Liang Zhou
Pages: 4717-4725
Published online on: 04 March 2019

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Article

Association between TP53 genetic polymorphisms and the methylation and expression of miR‑34a, 34b/c in colorectal cancer tissues

Hak Hoon Jun, Kyubum Kwack, Keun Hee Lee, Jung Oh Kim, Han Sung Park, Chang Soo Ryu, Jeong Yong Lee, Daeun Ko, Jong Woo Kim, Nam Keun Kim
Pages: 4726-4734
Published online on: 01 March 2019

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Article

Discovery of LDD‑1075 as a potent FLT3 inhibitor

Kyoung Bin Yoon, Hyo Jeong Lee, Hye Jin Chung, Jungeun Lee, Jungil Choi, Jeong Doo Heo, Yong‑Chul Kim, Sun‑Young Han
Pages: 4735-4741
Published online on: 01 March 2019

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Retraction Open Access

[Retracted] Aspirin inhibits growth of ovarian cancer by upregulating caspase-3 and downregulating bcl-2

Lin Li, Xiaogang Mao, Xiaomin Qin, Min Zhou, Hui Xing, Fan Dong, Xiaoyuan Jiang, Wenhui Zhuang
Pages: 4742-4742
Published online on: 04 March 2019

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July-2026 Volume 32 Issue 1

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu-Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing
Article Number: 321
Published online on: 02 June 2026

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Correction Open Access

[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 320
Published online on: 02 June 2026

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Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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Journal Cover
August-2026 Volume 32 Issue 2

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Superior cancer detection with transperineal biopsy in patients with an elevated prostate‑specific antigen level and a PI‑RADS score of 3‑4: A retrospective cohort study

Jun Zhang, Hui Zheng
Article Number: 375
Published online on: 25 June 2026

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Association between fibroblast activation protein α expression and immune environment in gastric cancer

Kosuke Kubo, Yukinori Kurokawa, Takaomi Hagi, Shinnosuke Nagano, Tsuyoshi Takahashi, Takuro Saito, Kazuyoshi Yamamoto, Kota Momose, Kotaro Yamashita, Koji Tanaka, Tomoki Makino, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki
Article Number: 374
Published online on: 25 June 2026

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Clinicopathological features and therapeutic advances in primary pulmonary lymphoepithelioma‑like carcinoma (Review)

Yong Chen, Yonglin Yu, Xiaoju Chen
Article Number: 373
Published online on: 25 June 2026

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Expression of Concern Open Access

[Expression of Concern] Myricetin inhibits migration and invasion of hepatocellular carcinoma MHCC97H cell line by inhibiting the EMT process

Hongxin Ma, Lei Zhu, Jingna Ren, Benlong Rao, Maomao Sha, Yi Kuang, Weigan Shen, Zhengxin Xu
Article Number: 372
Published online on: 24 June 2026

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FBXL5 depletion as a novel strategy against osteosarcoma: Evidence for MEK/ERK inhibition and enhanced therapeutic sensitivity

Yan-Chao Ma, Wen-Ming Zhou, Yong-Qiang Shi, Yan-Bo Dong, Hai-Hong Zhang, Wei Nan
Article Number: 371
Published online on: 24 June 2026

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Androgen receptor drives lenvatinib resistance in hepatocellular carcinoma through transcriptional activation of EIF3I and a downstream ceRNA axis

Changfeng Liu, Bing Zhang, Ye Jin, Zhi Chen, Miaomiao Wang, Zujian Wu
Article Number: 370
Published online on: 24 June 2026

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SUMOylation inhibitor TAK‑981 suppresses proliferation and induces apoptosis in SK‑UT‑1B uterine leiomyosarcoma cells

Hosouk Joung, Hyunju Liu
Article Number: 369
Published online on: 24 June 2026

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Methylation of the BMP6, BRCA1, ESR2, GSTP1 and TIMP3 genes in Mexican women with breast cancer and benign disease

Samantha Rebeca De La Torre‑Guzmán, Andrea Marlene García Muro, Brenda Pelayo‑Chávez, Carolina Vázquez‑Gastélum, Martha Patricia Gallegos‑Arreola, Ernesto Soto‑Reyes, Sergio Osvaldo Meza‑Chavolla, Josefina Yoaly Sánchez‑López
Article Number: 368
Published online on: 24 June 2026

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Identification of neoadjuvant chemoradiotherapy resistance‑associated proteins in locally advanced rectal cancer: A pilot study

Jiang-Yi He, Yan Dong, Can Chen, Fang-Hao Lu, Feng-Wei Ran, Qiong Ding, Yun Du, Tao-Rui Liu, Yu-Ying Zhang, Teng Wang, Yu-Han Chen, Xiang Zhao, Sen-Lin Xu, Jian-Jun Li
Article Number: 367
Published online on: 24 June 2026

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Overexpression of EZH2 is associated with clinicopathological parameters and poor prognosis in gliomas

Can Peng, Wei Chen, Jun Yang, Li Wang, Lixia Lu, Rong Ge
Article Number: 366
Published online on: 24 June 2026

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Correction Open Access

[Corrigendum] Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF‑1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase‑3 signaling pathway in small cell lung cancer

Wenli Jiang, Linghong Meng, Guangming Xu, Cuiting Lv, Hongliang Wang, He Tian, Ruohua Chen, Binghua Jiao, Bingui Wang, Caiguo Huang
Article Number: 365
Published online on: 22 June 2026

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A HRH1‑YAP1 feedback loop drives pancreatic cancer progression and predicts therapeutic response

Junliang Chen, Jun Wen
Article Number: 364
Published online on: 19 June 2026

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Case Report Open Access

Salivary duct carcinoma with heterotopic ossification in the parotid gland: A case report

Yutaro Fukuma, Mitsuaki Ishida, Akinori Sasaki, Tsuyoshi Jinnin, Tetsuya Terada, Shin-Ichi Haginomori, Yoshinobu Hirose
Article Number: 363
Published online on: 19 June 2026

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Pathological fracture of primary lymphoma of bone: A case report on diagnosis and novel surgical management

Duc Thanh Tran, Van Khanh Nguyen, Tran Quang Sang Nguyen, Minh Quang Dang, Van Anh Nguyen, The Hung Le, Tuyet Thanh Hai Tran, Van Cong Tran, Thi Thu Hien Tran, Trung Dung Tran
Article Number: 362
Published online on: 19 June 2026

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Review Open Access

Application and challenges of chimeric antigen receptor T cell therapy in the treatment of acute myeloid leukemia (Review)

Jingjing Zhang, Feilin Wang, Dandan Sui, Ziyi Huang, Yijian Chen
Article Number: 361
Published online on: 19 June 2026

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Prognostic value of the preoperative lactate dehydrogenase‑to‑albumin ratio in patients with gastrointestinal cancer

Yean Yu, Li Yan, Kun Lv, Tianhui Huang
Article Number: 360
Published online on: 18 June 2026

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[Corrigendum] Overexpression of lncRNA AFAP1‑AS1 promotes cell proliferation and invasion in gastric cancer  

Zhouxiao Li, Zhili Ding, Dawei Rong, Weiwei Tang, Hongyong Cao
Article Number: 359
Published online on: 18 June 2026

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Case Report Open Access

Safe management of sequential chemotherapy in a hemodialysis patient with metastatic colorectal cancer: A case report

Rika Sasaki, Nobuhito Hara, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Masayuki Takeda
Article Number: 358
Published online on: 18 June 2026

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Anti‑CD20 and ‑PD‑1 antibody effects on proliferation, apoptosis and cell cycle of endometrial cancer cells

Jinqiu Su, Jiayuan Du, Yaojie Yu, Mei Feng, Qiuyue Huang, Bing Liu, He Wang
Article Number: 357
Published online on: 17 June 2026

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CD47 monoclonal antibody enhances the inhibitory effect of anti‑HER2 chimeric antigen receptor macrophages on ovarian cancer

Jie Qiao, Qing Kou, Ji Qiu
Article Number: 356
Published online on: 17 June 2026

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Correction Open Access

[Corrigendum] Temozolomide abrogates the aggressiveness of urothelial carcinoma cells by enhancing senescence and depleting the side population

Na-Yon Kim, Sung-Hyun Hwang, Yeseul Yang, Yongbaek Kim
Article Number: 355
Published online on: 17 June 2026

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Case Report

Initial chemotherapy decreases transfusion dependence and enables definitive therapy in metastatic thymoma complicated by pure red cell aplasia: A case report

Nobuhito Hara, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Shinichi Ochi, Ryo Miyata, Masatsugu Hamaji, Sayaka Ando, Maiko Takeda, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 354
Published online on: 16 June 2026

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Bioinformatics analysis of proteins in the complement and coagulation cascades in colon cancer: Discovering the potential biomarker SERPINA1

Da Lian, Daixin Hou, Kunpeng Liu, Hao Jiang, Pengyu Xie
Article Number: 353
Published online on: 16 June 2026

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Circulating miRNA‑30a is associated with favorable therapeutic outcome in patients with gastric cancer treated with neoadjuvant chemotherapy

Vasileia Kokala‑dimitropoulou, Alexandros Mitrousias, Athanasios Tsiatouras, Aigli Vakrakou, Pantelis T. Antonakis, Manousos M. Konstantoulakis
Article Number: 352
Published online on: 16 June 2026

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Case Report Open Access

Salvage robotic‑assisted subtotal esophagectomy after chemoradiotherapy for unresectable locally advanced esophageal sarcoma: A case report

Masaaki Yamamoto, Atsushi Takeno, Kiyoshi Mori, Yumiko Hirose, Shinji Tokuyama, Yuki Matsui, Reishi Toshiyama, Kenji Kawai, Yusuke Takahashi, Kenji Sakai, Naoki Hama, Takeshi Kato, Koji Takami, Motohiro Hirao
Article Number: 351
Published online on: 16 June 2026

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A prognostic senescence‑related long non‑coding RNA signature identifies cold and hot tumors of stomach adenocarcinoma

Chenxi He, Fanting Kong, Baojuan Han, Litao Lv, Xiaoling Wang, Xiangguang Kong, Qingjiao Zeng, Peipei Zhou
Article Number: 350
Published online on: 16 June 2026

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Double vs. single autologous stem cell transplantation in patients with multiple myeloma and high‑risk factors: A systematic review and meta‑analysis

Sibei Qin, Yusi Liu, Peng Zhang, Qionglin Zhou, Xiayan Xu, Danbo Liu, Fang Du, Jiao Chen, Lingyun Zhou, Weiling Cao, Haifei Chen
Article Number: 349
Published online on: 16 June 2026

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Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Longlong Luo, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Josephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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