|
1
|
Zhu AX, Hong TS, Hezel AF and Kooby DA:
Current management of gallbladder carcinoma. Oncologist.
15:168–181. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Sharma A, Sharma KL, Gupta A, Yadav A and
Kumar A: Gallbladder cancer epidemiology, pathogenesis and
molecular genetics: Recent update. World J Gastroenterol.
23:3978–3998. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Aloia TA, Járufe N, Javle M, Maithel SK,
Roa JC, Adsay V, Coimbra FJ and Jarnagin WR: Gallbladder cancer:
Expert consensus statement. HPB; Oxford: 17. pp. 681–690. 2015,
PubMed/NCBI
|
|
4
|
Kanthan R, Senger JL, Ahmed S and Kanthan
SC: Gallbladder cancer in the 21st century. J Oncol 2015.
9674722015.
|
|
5
|
Sun HD, Huang SX and Han QB: Diterpenoids
from Isodon species and their biological activities. Nat
Prod Rep. 23:673–698. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wang F, Li XM and Liu JK: New terpenoids
from Isodon sculponeata. Chem Pharm Bull; Tokyo: 57:pp.
525–527. 2009, PubMed/NCBI
|
|
7
|
Jiao K, Li HY, Zhang P, Pi HF, Ruan HL and
Wu JZ: Three new ursane-type triterpenoids from the aerial parts of
Isodon excisoides. J Asian Nat Prod Res. 15:962–968. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Huang H, Sun H and Zhao S: Flavonoids from
Isodon oresbius. Phytochemistry. 42:1247–1248. 1996.
View Article : Google Scholar
|
|
9
|
Kashyap D, Tuli HS and Sharma AK: Ursolic
acid (UA): A metabolite with promising therapeutic potential. Life
Sci. 146:201–213. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
López-Hortas L, Pérez-Larrán P,
González-Muñoz MJ, Falqué E and Domínguez H: Recent developments on
the extraction and application of ursolic acid. A review. Food Res
Int. 103:130–149. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Prasad S, Tyagi AK and Aggarwal BB:
Chemosensitization by ursolic acid: A new avenue for cancer
therapy. Role of nutraceuticals in cancer chemosensitization.
Bharti AC and Aggarwal BB: Academic Press; Cambridge,
Massachusetts: pp. 99–109. 2018, View Article : Google Scholar
|
|
12
|
He W, Shi F, Zhou ZW, Li B, Zhang K, Zhang
X, Ouyang C, Zhou SF and Zhu X: A bioinformatic and mechanistic
study elicits the antifibrotic effect of ursolic acid through the
attenuation of oxidative stress with the involvement of ERK,
PI3K/Akt, and p38 MAPK signaling pathways in human hepatic stellate
cells and rat liver. Drug Des Devel Ther. 9:3989–4104.
2015.PubMed/NCBI
|
|
13
|
Weng H, Tan ZJ, Hu YP, Shu YJ, Bao RF,
Jiang L, Wu XS, Li ML, Ding Q, Wang XA, et al: Ursolic acid induces
cell cycle arrest and apoptosis of gallbladder carcinoma cells.
Cancer Cell Int. 14:962014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Huang da W, Sherman BT and Lempicki RA:
Bioinformatics enrichment tools: Paths toward the comprehensive
functional analysis of large gene lists. Nucleic Acids Res.
37:1–13. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Huang da W, Sherman BT and Lempicki RA:
Systematic and integrative analysis of large gene lists using DAVID
bioinformatics resources. Nature Protoc. 4:44–57. 2009. View Article : Google Scholar
|
|
17
|
Yang YC, Wei MC and Huang TC: Optimisation
of an ultrasound-assisted extraction followed by RP-HPLC separation
for the simultaneous determination of oleanolic acid, ursolic acid
and oridonin content in Rabdosia rubescens. Phytochem Anal.
23:627–636. 2012. View
Article : Google Scholar : PubMed/NCBI
|
|
18
|
Jiang B, Hou AJ, Li ML, Li SH, Han QB,
Wang SJ, Lin ZW and Sun HD: Cytotoxic ent-kaurane diterpenoids from
Isodon sculponeata. Planta Med. 68:921–925. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ali MS, Ibrahim SA, Jalil S and Choudhary
MI: Ursolic acid: A potent inhibitor of superoxides produced in the
cellular system. Phytother Res. 21:558–561. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Seebacher W, Simic N, Weis R, Saf R and
Kunert O: Complete assignments of 1H and 13C
NMR resonances of oleanolic acid, 18α-oleanolic acid, ursolic acid
and their 11-oxo derivatives. Magn Reson Chem. 41:636–638. 2003.
View Article : Google Scholar
|
|
21
|
Fulda S and Debatin KM: Extrinsic versus
intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene.
25:4798–4811. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Savva CG, Totokotsopoulos S, Nicolaou KC,
Neophytou CM and Constantinou AI: Selective activation of TNFR1 and
NF-κB inhibition by a novel biyouyanagin analogue promotes
apoptosis in acute leukemia cells. BMC Cancer. 16:2792016.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Annibaldi A and Meier P: Checkpoints in
TNF-induced cell death: Implications in inflammation and cancer.
Trends Mol Med. 24:49–65. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Woźniak Ł, Skąpska S and Marszałek K:
Ursolic acid-A pentacyclic triterpenoid with a wide spectrum of
pharmacological activities. Molecules. 20:20614–20641. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Jung J, Seo J, Kim J and Kim JH: Ursolic
acid causes cell death in PC-12 cells by inducing apoptosis and
impairing autophagy. Anticancer Res. 38:847–853. 2018.PubMed/NCBI
|
|
26
|
Lu CC, Huang BB, Liao PJ and Yen GC:
Ursolic acid triggers nonprogrammed death (necrosis) in human
glioblastoma multiforme DBTRG-05MG cells through MPT pore opening
and ATP decline. Mol Nutr Food Res. 58:2146–2156. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Wang X, Zhang F, Yang L, Mei Y, Long H,
Zhang X, Zhang J, Qimuge-Suyila and Su X: Ursolic acid inhibits
proliferation and induces apoptosis of cancer cells in vitro and in
vivo. J Biomed Biotechnol 2011. 4193432011.
|
|
28
|
Wu CC, Cheng CH, Lee YH, Chang IL, Chen
HY, Hsieh CP and Chueh PJ: Ursolic acid triggers apoptosis in human
osteosarcoma cells via caspase activation and the ERK1/2 MAPK
pathway. J Agric Food Chem. 64:4220–4226. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Meng Y, Lin ZM, Ge N, Zhang DL, Huang J
and Kong F: Ursolic acid induces apoptosis of prostate cancer cells
via the PI3K/Akt/mTOR pathway. Am J Chin Med. 43:1471–1486. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Gai L, Cai N, Wang L, Xu X and Kong X:
Ursolic acid induces apoptosis via Akt/NF-κB signaling suppression
in T24 human bladder cancer cells. Mol Med Rep. 7:1673–1677. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Zhang L, Wen X, Li M, Li S and Zhao H:
Targeting cancer stem cells and signaling pathways by resveratrol
and pterostilbene. Biofactors. 44:61–68. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Wang L, Yue Z, Guo M, Fang L, Bai L, Li X,
Tao Y, Wang S, Liu Q, Zhi D and Zhao H: Dietary flavonoid
hyperoside induces apoptosis of activated human LX-2 hepatic
stellate cell by suppressing canonical NF-κB signaling. Biomed Res
Int 2016. 10685282016.
|
|
33
|
Cui H, Yuan J, Du X, Wang M, Yue L and Liu
J: Ethyl gallate suppresses proliferation and invasion in human
breast cancer cells via Akt-NF-κB signaling. Oncol Rep.
33:1284–1290. 2015. View Article : Google Scholar : PubMed/NCBI
|
