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Primary osteosarcoma in elderly patients: A report of three cases

  • Authors:
    • Qiang Xu
    • Tian Gao
    • Bin Zhang
    • Jin Zeng
    • Min Dai
  • View Affiliations / Copyright

    Affiliations: Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi 330006, P.R. China
    Copyright: © Xu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 990-996
    |
    Published online on: June 7, 2019
       https://doi.org/10.3892/ol.2019.10446
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Abstract

Osteosarcoma is the most common type of primary malignant bone tumor in children and young adults. However, primary osteosarcoma in elderly patients is rare. The present study reports 3 cases of advanced osteosarcoma in elderly patients. The pathological findings in all 3 cases confirmed the diagnosis of primary osteosarcoma. Notably, each patient received different treatment options. Chemoradiotherapy was recommended in case 1 due to the age of the patient. However, the patient requested to be discharged and was lost to follow‑up. Conversely, in case 2, the 62‑year‑old female patient underwent systemic chemotherapy, but no surgical treatment, and in case 3, the 51‑year‑old male patient underwent complete tumor resection and received systemic chemotherapy for late tumor recurrence. Early diagnosis of osteosarcoma in elderly patients is difficult, and misdiagnosis or a missed diagnosis is common. In clinical practice, bone tumors in elderly patients should be investigated carefully. Imaging examinations are essential for diagnosis, and biopsy is required for confirmation. However, the efficacy of chemotherapy for elderly patients with primary osteosarcoma remains uncertain. Collectively, due to the small number of reports of osteosarcoma in the elderly population, the 3 cases in the present study raise awareness of this rare condition.
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Copy and paste a formatted citation
Spandidos Publications style
Xu Q, Gao T, Zhang B, Zeng J and Dai M: Primary osteosarcoma in elderly patients: A report of three cases. Oncol Lett 18: 990-996, 2019.
APA
Xu, Q., Gao, T., Zhang, B., Zeng, J., & Dai, M. (2019). Primary osteosarcoma in elderly patients: A report of three cases. Oncology Letters, 18, 990-996. https://doi.org/10.3892/ol.2019.10446
MLA
Xu, Q., Gao, T., Zhang, B., Zeng, J., Dai, M."Primary osteosarcoma in elderly patients: A report of three cases". Oncology Letters 18.2 (2019): 990-996.
Chicago
Xu, Q., Gao, T., Zhang, B., Zeng, J., Dai, M."Primary osteosarcoma in elderly patients: A report of three cases". Oncology Letters 18, no. 2 (2019): 990-996. https://doi.org/10.3892/ol.2019.10446
Copy and paste a formatted citation
x
Spandidos Publications style
Xu Q, Gao T, Zhang B, Zeng J and Dai M: Primary osteosarcoma in elderly patients: A report of three cases. Oncol Lett 18: 990-996, 2019.
APA
Xu, Q., Gao, T., Zhang, B., Zeng, J., & Dai, M. (2019). Primary osteosarcoma in elderly patients: A report of three cases. Oncology Letters, 18, 990-996. https://doi.org/10.3892/ol.2019.10446
MLA
Xu, Q., Gao, T., Zhang, B., Zeng, J., Dai, M."Primary osteosarcoma in elderly patients: A report of three cases". Oncology Letters 18.2 (2019): 990-996.
Chicago
Xu, Q., Gao, T., Zhang, B., Zeng, J., Dai, M."Primary osteosarcoma in elderly patients: A report of three cases". Oncology Letters 18, no. 2 (2019): 990-996. https://doi.org/10.3892/ol.2019.10446
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