Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
September-2019 Volume 18 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
September-2019 Volume 18 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML

  • Supplementary Files
    • Supplementary_Data.pdf
Article

Proteomics analysis of proteins interacting with heat shock factor 1 in squamous cell carcinoma of the cervix

  • Authors:
    • Lingli Zhang
    • Zhe Hu
    • Ying Zhang
    • Jinzhi Huang
    • Xuefen Yang
    • Jiafeng Wang
  • View Affiliations / Copyright

    Affiliations: Department of Gynaecology and Obstetrics, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524001, P.R. China, Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524001, P.R. China, Stem Cell Research and Cellular Therapy Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524001, P.R. China
  • Pages: 2568-2575
    |
    Published online on: June 27, 2019
       https://doi.org/10.3892/ol.2019.10539
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Protein interactions are crucial for maintaining homeostasis. Heat shock factor 1 (HSF1), a transcription factor that interacts with various proteins, is highly expressed in squamous cell carcinoma (SCC) of the cervix. The aim of the present study was to investigate the protein interaction profile of HSF1 in cervical SCC. Proteins interacting with HSF1 in SCC tissue and non‑cancerous control (Ctrl) tissue were obtained by immunoprecipitation, separated by SDS‑PAGE, identified by matrix‑assisted laser desorption/ionization‑time‑of‑flight mass spectrometry and analyzed using bioinformatics methods. A total of 220 and 241 proteins were identified by mass spectrometry in the tissues of Ctrl and SCC samples, respectively, among which 172 were detected exclusively in SCC (Pro‑S), 151 exclusively in Ctrl (Pro‑C) and 69 in both groups (Pro‑B). The protein interaction profiles were different in each group; the STRING database identified three proteins that interacted with HSF1 directly, including insulin‑like growth factor 1 receptor and small nuclear RNA‑activating protein complex subunit 4 in Pro‑C and small ubiquitin‑related modifier 1 in Pro‑S. Functional enrichment analysis of Gene Ontology revealed that the top terms were alternative splicing in Pro‑S and polymorphism in Pro‑C. In Pro‑S, more categories were related to protein modification, such as phosphorylation, ubiquitination and acetylation. Therefore, HSF1 may influence the occurrence and development of cervical SCC by interacting with specific proteins.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

Hsu HC, Li X, Curtin JP, Goldberg JD and Schiff PB: Surveillance epidemiology and end results analysis demonstrates improvement in overall survival for cervical cancer patients treated in the era of concurrent chemoradiotherapy. Front Oncol. 5:812015. View Article : Google Scholar : PubMed/NCBI

2 

Chen W, Zheng R, Baade PD, Zhang S, Zeng H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China, 2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI

3 

Ritossa F: A new puffing pattern induced by temperature shock and DNP in Drosophila. Experientia. 18:571–573. 1962. View Article : Google Scholar

4 

Baler R, Dahl G and Voellmy R: Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF1. Mol Cell Biol. 13:2486–2496. 1993. View Article : Google Scholar : PubMed/NCBI

5 

Shi Y, Mosser DD and Morimoto RI: Molecular chaperones as HSF1-specific transcriptional repressors. Genes Dev. 12:654–666. 1998. View Article : Google Scholar : PubMed/NCBI

6 

Santagata S, Hu R, Lin NU, Mendillo ML, Collins LC, Hankinson SE, Schnitt SJ, Whitesell L, Tamimi RM, Lindquist S and Ince TA: High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer. Proc Natl Acad Sci USA. 108:18378–18383. 2011. View Article : Google Scholar : PubMed/NCBI

7 

Powell CD, Paullin TR, Aoisa C, Menzie CJ, Ubaldini A and Westerheide SD: The heat shock transcription factor hsf1 induces ovarian cancer epithelial-mesenchymal transition in a 3D spheroid growth model. PLoS One. 11:e01683892016. View Article : Google Scholar : PubMed/NCBI

8 

Yu S, Cheng M, Hou L, Zhang W, Liu B and Linghu H: HSF1 expression in cervical carcinoma and its correlation with clinical pathological characteristics and prognosis. J Third Mil Med Univ. 36:560–563. 2017.(In Chinese).

9 

Calderwood SK: Elevated levels of HSF1 indicate a poor prognosis in breast cancer. Future Oncol. 8:399–401. 2012. View Article : Google Scholar : PubMed/NCBI

10 

Dai C, Whitesell L, Rogers AB and Lindquist S: Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis. Cell. 130:1005–1018. 2007. View Article : Google Scholar : PubMed/NCBI

11 

Mendillo ML, Santagata S, Koeva M, Bell GW, Hu R, Tamimi RM, Fraenkel E, Ince TA, Whitesell L and Lindquist S: HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers. Cell. 150:549–562. 2012. View Article : Google Scholar : PubMed/NCBI

12 

Scherz-Shouval R, Santagata S, Mendillo ML, Sholl LM, Ben-Aharon I, Beck AH, Dias-Santagata D, Koeva M, Stemmer SM, Whitesell L and Lindquist S: The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy. Cell. 158:564–578. 2014. View Article : Google Scholar : PubMed/NCBI

13 

Zhang L, Yang M, Wang Q, Liu M, Liang Q, Zhang H and Xiao X: HSF1 regulates expression of G-CSF through the binding element for NF-IL6/CCAAT enhancer binding protein beta. Mol Cell Biochem. 352:11–17. 2011. View Article : Google Scholar : PubMed/NCBI

14 

Wang X, Grammatikakis N, Siganou A, Stevenson MA and Calderwood SK: Interactions between extracellular signal-regulated protein kinase 1, 14-3-3epsilon, and heat shock factor 1 during stress. J Biol Chem. 279:49460–49469. 2004. View Article : Google Scholar : PubMed/NCBI

15 

Eroglu B, Min JN, Zhang Y, Szurek E, Moskophidis D, Eroglu A and Mivechi NF: An essential role for heat shock transcription factor binding protein 1 (HSBP1) during early embryonic development. Dev Biol. 386:448–460. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Luo T, Fu J, Xu A, Su B, Ren Y, Li N, Zhu J, Zhao X, Dai R, Cao J, et al: PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression. Autophagy. 12:1355–1371. 2016. View Article : Google Scholar : PubMed/NCBI

17 

Ostling P, Björk JK, Roos-Mattjus P, Mezger V and Sistonen L: Heat shock factor 2 (HSF2) contributes to inducible expression of hsp genes through interplay with HSF1. J Biol Chem. 282:7077–7086. 2007. View Article : Google Scholar : PubMed/NCBI

18 

Xie Y, Chen C, Stevenson MA, Auron PE and Calderwood SK: Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6. J Biol Chem. 277:11802–11810. 2002. View Article : Google Scholar : PubMed/NCBI

19 

Wang ET, Sandberg R, Luo S, Khrebtukova I, Zhang L, Mayr C, Kingsmore SF, Schroth GP and Burge CB: Alternative isoform regulation in human tissue transcriptomes. Nature. 456:470–476. 2008. View Article : Google Scholar : PubMed/NCBI

20 

Rong C, Feng Y and Ye Z: Notch is a critical regulator in cervical cancer by regulating Numb splicing. Oncol Lett. 13:2465–2470. 2017. View Article : Google Scholar : PubMed/NCBI

21 

Gaytan-Cervantes J, Gonzalez-Torres C, Maldonado V, Zampedri C, Ceballos-Cancino G and Melendez-Zajgla J: Protein Sam68 regulates the alternative splicing of survivin DEx3. J Biol Chem. 292:13745–13757. 2017. View Article : Google Scholar : PubMed/NCBI

22 

Nikoshkov A, Broliden K, Attarha S, Sviatoha V, Hellström AC, Mints M and Andersson S: Expression pattern of the PRDX2, RAB1A, RAB1B, RAB5A and RAB25 genes in normal and cancer cervical tissues. Int J Oncol. 46:107–112. 2015. View Article : Google Scholar : PubMed/NCBI

23 

Bradley T, Cook ME and Blanchette M: SR proteins control a complex network of RNA-processing events. RNA. 21:75–92. 2015. View Article : Google Scholar : PubMed/NCBI

24 

Xia W, Guo Y, Vilaboa N, Zuo J and Voellmy R: Transcriptional activation of heat shock factor HSF1 probed by phosphopeptide analysis of factor 32P-labeled in vivo. J Biol Chem. 273:8749–8755. 1998. View Article : Google Scholar : PubMed/NCBI

25 

Holmberg CI, Hietakangas V, Mikhailov A, Rantanen JO, Kallio M, Meinander A, Hellman J, Morrice N, MacKintosh C, Morimoto RI, et al: Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1. EMBO J. 20:3800–3810. 2001. View Article : Google Scholar : PubMed/NCBI

26 

Chu B, Soncin F, Price BD, Stevenson MA and Calderwood SK: Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional activation by heat shock factor-1. J Biol Chem. 271:30847–30857. 1996. View Article : Google Scholar : PubMed/NCBI

27 

Cotto JJ, Kline M and Morimoto RI: Activation of heat shock factor 1 DNA binding precedes stress-induced serine phosphorylation. Evidence for a multistep pathway of regulation. J Biol Chem. 271:3355–3358. 1996. View Article : Google Scholar : PubMed/NCBI

28 

Yin J, Jiang XY, Qi W, Ji CG, Xie XL, Zhang DX, Cui ZJ, Wang CK, Bai Y, Wang J and Jiang HQ: piR-823 contributes to colorectal tumorigenesis by enhancing the transcriptional activity of HSF1. Cancer Sci. 108:1746–1756. 2017. View Article : Google Scholar : PubMed/NCBI

29 

Azizmohammadi S, Azizmohammadi S, Safari A, Kaghazian M, Sadrkhanlo M, Behnod V and Seifoleslami M: High-Level Expression of RIPK4 and EZH2 contributes to lymph node metastasis and predicts favorable prognosis in patients with cervical cancer. Oncol Res. 25:495–501. 2017. View Article : Google Scholar : PubMed/NCBI

30 

Huang X, McGann JC, Liu BY, Hannoush RN, Lill JR, Pham V, Newton K, Kakunda M, Liu J, Yu C, et al: Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling. Science. 339:1441–1445. 2013. View Article : Google Scholar : PubMed/NCBI

31 

Dayalan Naidu S, Sutherland C, Zhang Y, Risco A, de la Vega L, Caunt CJ, Hastie CJ, Lamont DJ, Torrente L, Chowdhry S, et al: Heat shock factor 1 Is a substrate for p38 mitogen-activated protein kinases. Mol Cell Biol. 36:2403–2417. 2016. View Article : Google Scholar : PubMed/NCBI

32 

Hietakangas V, Ahlskog JK, Jakobsson AM, Hellesuo M, Sahlberg NM, Holmberg CI, Mikhailov A, Palvimo JJ, Pirkkala L and Sistonen L: Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1. Mol Cell Biol. 23:2953–2968. 2003. View Article : Google Scholar : PubMed/NCBI

33 

Banks GT, Haas MA, Line S, Shepherd HL, Alqatari M, Stewart S, Rishal I, Philpott A, Kalmar B, Kuta A, et al: Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse. J Neurosci. 31:5483–5494. 2011. View Article : Google Scholar : PubMed/NCBI

34 

Szeliga M, Obara-Michlewska M, Matyja E, Łazarczyk M, Lobo C, Hilgier W, Alonso FJ, Márquez J and Albrecht J: Transfection with liver-type glutaminase cDNA alters gene expression and reduces survival, migration and proliferation of T98G glioma cells. Glia. 57:1014–1023. 2009. View Article : Google Scholar : PubMed/NCBI

35 

Antonietti P, Linder B, Hehlgans S, Mildenberger IC, Burger MC, Fulda S, Steinbach JP, Gessler F, Rödel F, Mittelbronn M and Kögel D: Interference with the HSF1/HSP70/bag3 pathway primes glioma cells to matrix detachment and BH3 mimetic-induced apoptosis. Mol Cancer Ther. 16:156–168. 2017. View Article : Google Scholar : PubMed/NCBI

36 

Beyer S, Zhu J, Mayr D, Kuhn C, Schulze S, Hofmann S, Dannecker C, Jeschke U and Kost BP: Histone H3 acetyl K9 and histone H3 tri methyl K4 as prognostic markers for patients with cervical cancer. Int J Mol Sci. 18(pii): E4772017. View Article : Google Scholar : PubMed/NCBI

37 

Col E, Hoghoughi N, Dufour S, Penin J, Koskas S, Faure V, Ouzounova M, Hernandez-Vargash H, Reynoird N, Daujat S, et al: Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock. Sci Rep. 7:54182017. View Article : Google Scholar : PubMed/NCBI

38 

Liu J, Zheng Q, Deng Y, Cheng CS, Kallenbach NR and Lu M: A seven-helix coiled coil. Proc Natl Acad Sci USA. 103:15457–15462. 2006. View Article : Google Scholar : PubMed/NCBI

39 

Shinada K, Tsukiyama T, Sho T, Okumura F, Asaka M and Hatakeyama S: RNF43 interacts with NEDL1 and regulates p53-mediated transcription. Biochem Biophys Res Commun. 404:143–147. 2011. View Article : Google Scholar : PubMed/NCBI

40 

Choi KS, Choi HJ, Lee JK, Im S, Zhang H, Jeong Y, Park JA, Lee IK, Kim YM and Kwon YG: The endothelial E3 ligase HECW2 promotes endothelial cell junctions by increasing AMOTL1 protein stability via K63-linked ubiquitination. Cell Signal. 28:1642–1651. 2016. View Article : Google Scholar : PubMed/NCBI

41 

Bahrami A, Hasanzadeh M, ShahidSales S, Yousefi Z, Kadkhodayan S, Farazestanian M, Joudi Mashhad M, Gharib M, Mahdi Hassanian S and Avan A: Clinical significance and prognosis value of Wnt signaling pathway in cervical cancer. J Cell Biochem. 118:3028–3033. 2017. View Article : Google Scholar : PubMed/NCBI

42 

Zhang R, Lu H, Lyu YY, Yang XM, Zhu LY, Yang GD, Jiang PC, Re Y, Song WW, Wang JH, et al: E6/E7-P53-POU2F1-CTHRC1 axis promotes cervical cancer metastasis and activates Wnt/PCP pathway. Sci Rep. 7:447442017. View Article : Google Scholar : PubMed/NCBI

43 

Li G, Song Y, Zhang Y, Wang H and Xie J: miR-34b Targets HSF1 to suppress cell survival in acute myeloid leukemia. Oncol Res. 24:109–116. 2016. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhang L, Hu Z, Zhang Y, Huang J, Yang X and Wang J: Proteomics analysis of proteins interacting with heat shock factor 1 in squamous cell carcinoma of the cervix. Oncol Lett 18: 2568-2575, 2019.
APA
Zhang, L., Hu, Z., Zhang, Y., Huang, J., Yang, X., & Wang, J. (2019). Proteomics analysis of proteins interacting with heat shock factor 1 in squamous cell carcinoma of the cervix. Oncology Letters, 18, 2568-2575. https://doi.org/10.3892/ol.2019.10539
MLA
Zhang, L., Hu, Z., Zhang, Y., Huang, J., Yang, X., Wang, J."Proteomics analysis of proteins interacting with heat shock factor 1 in squamous cell carcinoma of the cervix". Oncology Letters 18.3 (2019): 2568-2575.
Chicago
Zhang, L., Hu, Z., Zhang, Y., Huang, J., Yang, X., Wang, J."Proteomics analysis of proteins interacting with heat shock factor 1 in squamous cell carcinoma of the cervix". Oncology Letters 18, no. 3 (2019): 2568-2575. https://doi.org/10.3892/ol.2019.10539
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang L, Hu Z, Zhang Y, Huang J, Yang X and Wang J: Proteomics analysis of proteins interacting with heat shock factor 1 in squamous cell carcinoma of the cervix. Oncol Lett 18: 2568-2575, 2019.
APA
Zhang, L., Hu, Z., Zhang, Y., Huang, J., Yang, X., & Wang, J. (2019). Proteomics analysis of proteins interacting with heat shock factor 1 in squamous cell carcinoma of the cervix. Oncology Letters, 18, 2568-2575. https://doi.org/10.3892/ol.2019.10539
MLA
Zhang, L., Hu, Z., Zhang, Y., Huang, J., Yang, X., Wang, J."Proteomics analysis of proteins interacting with heat shock factor 1 in squamous cell carcinoma of the cervix". Oncology Letters 18.3 (2019): 2568-2575.
Chicago
Zhang, L., Hu, Z., Zhang, Y., Huang, J., Yang, X., Wang, J."Proteomics analysis of proteins interacting with heat shock factor 1 in squamous cell carcinoma of the cervix". Oncology Letters 18, no. 3 (2019): 2568-2575. https://doi.org/10.3892/ol.2019.10539
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team