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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2019 Volume 18 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

The role of ferroptosis in digestive system cancer (Review)

Yan Song, Hu Yang, Rui Lin, Kui Jiang, Bang‑Mao Wang
Pages: 2159-2164
Published online on: 05 July 2019

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Review Open Access

The true colors of autophagy in doxorubicin‑induced cardiotoxicity (Review)

Bin Xiao, Lang Hong, Xinyong Cai, Songbo Mei, Ping Zhang, Liang Shao
Pages: 2165-2172
Published online on: 05 July 2019

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Review Open Access

Role of cancer-associated fibroblasts in tumor structure, composition and the microenvironment in ovarian cancer (Review)

Wei Sun, Shilong Fu
Pages: 2173-2178
Published online on: 08 July 2019

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Review Open Access

Soft tissue sarcomas of the upper extremities: Maximizing treatment opportunities and outcomes (Review)

Jose Duran‑Moreno, Vasileios Kontogeorgakos, Anna Koumarianou
Pages: 2179-2191
Published online on: 05 July 2019

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Review Open Access

Long non‑coding RNA XIST predicting advanced clinical parameters in cancer: A Meta‑Analysis and case series study in a single institution (Review)

Changkai Deng, Xianliang Hu, Ke Wu, Juan Tan, Chao Yang
Pages: 2192-2202
Published online on: 09 July 2019

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Article Open Access

lncRNA‑CCDC26, as a novel biomarker, predicts prognosis in acute myeloid leukemia

Cunte Chen, Peipei Wang, Wenjian Mo, Yuping Zhang, Wei Zhou, Tingfen Deng, Ming Zhou, Xiaowei Chen, Shunqing Wang, Caixia Wang
Pages: 2203-2211
Published online on: 09 July 2019

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Article Open Access

Long non‑coding RNA HOTAIR promotes cancer cell energy metabolism in pancreatic adenocarcinoma by upregulating hexokinase‑2

Yu Ma, Mingyue Hu, Lingna Zhou, Sunkai Ling, Yuan Li, Bo Kong, Peilin Huang
Pages: 2212-2219
Published online on: 02 July 2019

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Article Open Access

Multi‑kinase inhibitors and cisplatin for head and neck cancer treatment in vitro

Roman C. Brands, Francesco De Donno, Marie Luise Knierim, Valentin Steinacker, Stefan Hartmann, Axel Seher, Alexander C. Kübler, Urs D. A. Müller‑Richter
Pages: 2220-2231
Published online on: 28 June 2019

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Article Open Access

MicroRNA‑589 serves as a tumor suppressor microRNA through directly targeting metastasis‑associated protein 2 in breast cancer

Jun Chu
Pages: 2232-2239
Published online on: 28 June 2019

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Article Open Access

lncRNA FLVCR1‑AS1 regulates cell proliferation, migration and invasion by sponging miR‑485‑5p in human cholangiocarcinoma

Wenqing Bao, Feng Cao, Shubin Ni, Jing Yang, Haidong Li, Zhenxi Su, Bin Zhao
Pages: 2240-2247
Published online on: 05 July 2019

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Article Open Access

Effects and significance of formononetin on expression levels of HIF‑1α and VEGF in mouse cervical cancer tissue

Yue Zhang, Chen Chen, Jun Zhang
Pages: 2248-2253
Published online on: 05 July 2019

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Article Open Access

Prognostic value of delta‑like protein 3 combined with thyroid transcription factor‑1 in small‑cell lung cancer

Li‑Xu Yan, Yan‑Hui Liu, Zhi Li, Dong‑Lan Luo, Yu‑Fa Li, Jing‑Hai Yan, Jia‑Tao Zhang, Chao Liu, Xun‑Hua Liu, Jiao He
Pages: 2254-2261
Published online on: 27 June 2019

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Article Open Access

Screening and identification of novel specific markers of breast cancer stem cells

Tingting Liu, Baojiang Li, Yunyun Jiang, Chunhui Zheng, Li Zhang, Yongsheng Wang
Pages: 2262-2269
Published online on: 27 June 2019

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Case Report Open Access

Osteochondroma of the coronoid process: A case report and review of the literature

Tianjun Lan, Xin Liu, Pei‑Sheng Liang, Qian Tao
Pages: 2270-2277
Published online on: 27 June 2019

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Article Open Access

Expression of RUNX3 gene and miR-363 in colorectal cancer and the relationship with clinicopathological features

Guofeng Li
Pages: 2278-2285
Published online on: 05 July 2019

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Article Open Access

Lentivirus‑mediated RNA interference targeting EBNA1 gene inhibits the growth of GT‑38 cells in vitro and in vivo

Jian Wang, Cunfu Liang, Fansheng Meng, Xiangwen Xu, Yan Wu, Lin Lu
Pages: 2286-2291
Published online on: 28 June 2019

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Article Open Access

Meta‑analysis of gene expression alterations and clinical significance of the HECT domain‑containing ubiquitin ligase HUWE1 in cancer

Chen Su, Tao Wang, Jiabao Zhao, Jia Cheng, Jingjing Hou
Pages: 2292-2303
Published online on: 05 July 2019

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Article Open Access

5‑Hydroxymethylcytosine as a potential epigenetic biomarker in papillary thyroid carcinoma

Mengying Tong, Shuhang Gao, Wenjing Qi, Chang Shi, Meng Qiu, Fang Yang, Shanshan Bai, Husha Li, Zhizhou Wang, Zhigang Sun, Lina Wang, Ying Che
Pages: 2304-2309
Published online on: 27 June 2019

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Article Open Access

Correlation analysis of mRNA expression and prognosis of hOGG1 gene polymorphism in patients with non-small cell lung cancer

Jing Wang, Puzhao Wu
Pages: 2310-2315
Published online on: 05 July 2019

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Article Open Access

Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer

Juan Li, Qian Wang, Liangliang Wang, Jing Wang, Dongxiao Wang, Zhaoqin Xin, Yilin Liu, Qinghua Zhao
Pages: 2316-2321
Published online on: 05 July 2019

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Article Open Access

Hepatocellular carcinoma grading and recurrence prediction using T1 mapping on gadolinium‑ethoxybenzyl diethylenetriamine pentaacetic acid‑enhanced magnetic resonance imaging

Xiali Qin, Tengfei Yang, Zhongkui Huang, Liling Long, Zhipeng Zhou, Wenmei Li, Yinjuan Gao, Mengzhu Wang, Xiaoyong Zhang
Pages: 2322-2329
Published online on: 04 July 2019

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Article Open Access

Integrative analysis of miRNA and mRNA expression profiles reveals a novel mRNA/miRNA signature to improve risk classification for patients with gastric cancer

Xiang Yin, Fumin Zhang, Zhongwu Guo, Weiyuan Kong, Yuanyuan Wang
Pages: 2330-2339
Published online on: 27 June 2019

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Article Open Access

VDAC1 is regulated by BRD4 and contributes to JQ1 resistance in breast cancer

Guochao Yang, Dianwei Zhou, Jun Li, Wei Wang, Wei Zhong, Wei Fan, Mancheng Yu, Hongtao Cheng
Pages: 2340-2347
Published online on: 27 June 2019

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Article Open Access

miR‑616 promotes breast cancer migration and invasion by targeting TIMP2 and regulating MMP signaling

Chao Yuan
Pages: 2348-2355
Published online on: 28 June 2019

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Article Open Access

Systematic re‑analysis strategy of serum indices identifies alkaline phosphatase as a potential predictive factor for cervical cancer

Jun Yu, Qianwen Zheng, Xiaoxing Ding, Bo Zheng, Xia Chen, Binghai Chen, Cong Shen, Yu Zhang, Xiaojin Luan, Yidan Yan, Wanyin Chen, Bing Xie, Min Wang, Jiajia Liu, Jie Fang, Xing Hu, Hong Li, Chen Qiao, Peifang Yang
Pages: 2356-2365
Published online on: 26 June 2019

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Article Open Access

Construction of subtype‑specific prognostic gene signatures for early‑stage non‑small cell lung cancer using meta feature selection methods

Chunshui Liu, Linlin Wang, Tianjiao Wang, Suyan Tian
Pages: 2366-2375
Published online on: 04 July 2019

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Article Open Access

Expression of septin 2 and association with clinicopathological parameters in colorectal cancer

Haoyu He, Junjun Li, Meng Xu, Ziliang Kan, Yang Gao, Caijun Yuan
Pages: 2376-2383
Published online on: 26 June 2019

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Article Open Access

Reverse first dorsal metacarpal artery flap repair of a right thumb epidermis granuloma: A case study

Zhiyong Luan, Biao Liu, Hongbo Jiang, Fengqi Gao, Baogang Yang
Pages: 2384-2387
Published online on: 05 July 2019

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Article Open Access

Gross tumor volume is an independent prognostic factor in patients with postoperative locoregional recurrence of esophageal squamous cell carcinoma

Yu Shi, Xiaolin Ge, Zhenzhen Gao, Shenxiang Liu, Xinchen Sun, Jinhua Luo
Pages: 2388-2393
Published online on: 26 June 2019

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Article Open Access

Impact of microRNA‑29b on natural killer cells in T‑cell acute lymphoblastic leukemia Corrigendum in /10.3892/ol.2020.12273

Fengyan Jin, Zhonghua Du, Yang Tang, Lixia Wang, Yanping Yang
Pages: 2394-2403
Published online on: 04 July 2019

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Article Open Access

Metformin improves the sensitivity of ovarian cancer cells to chemotherapeutic agents

Chen Yang, Nanan Zhao, Dandan Li, Ge Zou, Yan Chen
Pages: 2404-2411
Published online on: 04 July 2019

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Article Open Access

Population pharmacokinetics of sirolimus in pediatric patients with kaposiform hemangioendothelioma: A retrospective study

Dongdong Wang, Xiao Chen, Zhiping Li
Pages: 2412-2419
Published online on: 04 July 2019

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Article Open Access

Cinnamaldehyde causes apoptosis of myeloid‑derived suppressor cells through the activation of TLR4

Wanzhuo He, Wensheng Zhang, Qilin Zheng, Zheng Wei, Yuanyuan Wang, Minghua Hu, Fangli Ma, Ning Tao, Cong Luo
Pages: 2420-2426
Published online on: 28 June 2019

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Article Open Access

Helical and kinase domain mutations of PIK3CA, and their association with hormone receptor expression in breast cancer

Chittibabu Vatte, Ali Mohammed Al Amri, Cyril Cyrus, Shahanas Chathoth, Ahmed Alsayyah, Arafat Ahmad, Mohammed Shakil Akhtar, Nada Fehaid Alrashidi, Nithya Jayaseeli, Hamed Al Wadani, Alhussain Al Zahrani, Amein Kadhem Al Ali
Pages: 2427-2433
Published online on: 04 July 2019

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Article Open Access

Mitofusin 2 inhibits bladder cancer cell proliferation and invasion via the Wnt/β‑catenin pathway

Guofu Pang, Qun Xie, Juanjuan Yao
Pages: 2434-2442
Published online on: 05 July 2019

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Article Open Access

Overexpression of lncRNA GATA6‑AS inhibits cancer cell proliferation in mantle cell lymphoma by downregulating GLUT1

Zhenwei Fan, Xuan Wang, Peng Li, Chunli Mei, Min Zhang, Chunshan Zhao
Pages: 2443-2447
Published online on: 28 June 2019

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Article Open Access

HTR1D, TIMP1, SERPINE1, MMP3 and CNR2 affect the survival of patients with colon adenocarcinoma

Chunyan Zeng, Youxiang Chen
Pages: 2448-2454
Published online on: 28 June 2019

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Article Open Access

Expression of TRA2B in endometrial carcinoma and its regulatory roles in endometrial carcinoma cells

Dhruba Paudel, Yiqin Ouyang, Qingting Huang, Wei Zhou, Jianjun Wang, Maxwell Enayat Poorekhorsandi, Bipin Dhakal, Xiaowen Tong
Pages: 2455-2463
Published online on: 03 July 2019

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Article Open Access

Identification of key genes and pathways between type I and type II endometrial cancer using bioinformatics analysis

Kai Zhang, Huiyang Li, Ye Yan, Yuqin Zang, Ke Li, Yingmei Wang, Fengxia Xue
Pages: 2464-2476
Published online on: 28 June 2019

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Article Open Access

Downregulating SynCAM and MPP6 expression is associated with ovarian cancer progression

Feixue Xu, Xiaoqiang Si, Jingran Du, Feihua Xu, Aihong Yang, Caixia Zhang, Xiucai Zhang, Yongxiu Yang
Pages: 2477-2483
Published online on: 28 June 2019

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Article Open Access

Cancer associated fibroblasts are distinguishable from peri‑tumor fibroblasts by biological characteristics in TSCC

Pengfei Ba, Xiaojuan Zhang, Miao Yu, Linxia Li, Xiaoyu Duan, Mingying Wang, Shuyan Lv, Guo Fu, Pishan Yang, Chengzhe Yang, Qinfeng Sun
Pages: 2484-2490
Published online on: 04 July 2019

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Article Open Access

Downregulation of microRNA‑1246 inhibits tumor growth and promotes apoptosis of cervical cancer cells by targeting thrombospondin‑2

Ping Du, Yue‑Hua Lai, De‑Sheng Yao, Jun‑Ying Chen, Nan Ding
Pages: 2491-2499
Published online on: 05 July 2019

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Article Open Access

Screening of potential biomarkers in hepatitis C virus‑induced hepatocellular carcinoma using bioinformatic analysis

Jun Liu, Zhanzhong Ma, Yanming Liu, Liangyin Wu, Zhiwei Hou, Wenli Li
Pages: 2500-2508
Published online on: 05 July 2019

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Article Open Access

TIGAR promotes growth, survival and metastasis through oxidation resistance and AKT activation in glioblastoma

Zhi Tang, Zhengwen He
Pages: 2509-2517
Published online on: 05 July 2019

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Article Open Access

Effect of lncRNA THOR on proliferation and igration of colon cancer cells

Ying Lv, Xiuhua Yang, Lei Wang
Pages: 2518-2522
Published online on: 05 July 2019

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Article Open Access

MicroRNA-744 promotes carcinogenesis in osteosarcoma through targeting LATS2

Liangzhi Sun, Ming Liu, Suxian Luan, Yulin Shi, Qiang Wang
Pages: 2523-2529
Published online on: 26 June 2019

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Article Open Access

miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer Expression of Concern in /10.3892/ol.2026.15655

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Pages: 2530-2536
Published online on: 05 July 2019

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Article

Detection and clinical significance of circulating tumor cells in patients with nasopharyngeal carcinoma

Zunbei Wen, Zhongtai Li, Pangxiao Yong, Dunbo Liang, Di Xie, Haiwen Chen, Yongying Yang, Shiyang Wu, Cong Li, Zhen Cheng
Pages: 2537-2547
Published online on: 04 July 2019

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Article

Establishment of an insufficient radiofrequency ablation orthotopic nude mouse model of hepatocellular carcinoma to study the invasiveness and metastatic potential of residual cancer

Ning Zhang, Hua Zhu, Ye‑Hao Dong, Lu Wang
Pages: 2548-2553
Published online on: 02 July 2019

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Article

Cryptotanshinone inhibits lung cancer invasion via microRNA‑133a/matrix metalloproteinase 14 regulation

Huijuan Wang, Yanshan Zhang, Yingguo Zhang, Wenling Liu, Jihong Wang
Pages: 2554-2559
Published online on: 05 July 2019

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Article

Novel endoscopic treatment strategy for early esophageal cancer in cirrhotic patients with esophageal varices

Zheng‑Guo Xu, Yong‑Bing Zhao, Jin Yu, Jian‑Ying Bai, En Liu, Bo Tang, Shi‑Ming Yang
Pages: 2560-2567
Published online on: 27 June 2019

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Article

Proteomics analysis of proteins interacting with heat shock factor 1 in squamous cell carcinoma of the cervix

Lingli Zhang, Zhe Hu, Ying Zhang, Jinzhi Huang, Xuefen Yang, Jiafeng Wang
Pages: 2568-2575
Published online on: 27 June 2019

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Article

Bioinformatics analysis identifies potential chemoresistance‑associated genes across multiple types of cancer

Jingsheng Yuan, Lulu Tan, Zhijie Yin, Kaixiong Tao, Guobing Wang, Wenjia Shi, Jinbo Gao
Pages: 2576-2583
Published online on: 27 June 2019

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Article

Overexpression levels of cripto‑1 predict poor prognosis in patients with prostate cancer following radical prostatectomy

Yan Liu, Jianan Wang, Tong Yang, Ranlu Liu, Yong Xu
Pages: 2584-2591
Published online on: 04 July 2019

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Article

Whole‑exome sequencing of lobular endocervical glandular hyperplasia

Koichi Ida, Tsutomu Miyamoto, Akiko Takatsu, Hirofumi Ando, Ryoichi Asaka, Hodaka Takeuchi, Motoki Ono, Satoshi Yamada, Shiho Asaka, Tanri Shiozawa
Pages: 2592-2597
Published online on: 28 June 2019

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Article

RAB38 is a potential prognostic factor for tumor recurrence in non‑small cell lung cancer

Jia‑Juan Hsieh, Ming‑Mo Hou, John Wen‑Cheng Chang, Yung‑Chi Shen, Hsin‑Yi Cheng, Todd Hsu
Pages: 2598-2604
Published online on: 28 June 2019

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Article

Upregulation of lncRNA GATA6‑AS suppresses the migration and invasion of cervical squamous cell carcinoma by downregulating MTK‑1

Lan Chen, Xuming Wang, Limian Song, Dujuan Yao, Qianqian Tang, Jun Zhou
Pages: 2605-2611
Published online on: 04 July 2019

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Article

miR‑296‑3p targets APEX1 to suppress cell migration and invasion of non‑small‑cell lung cancer

Lifeng Wang, Ruilin Chen, Yongqing Zhang
Pages: 2612-2618
Published online on: 05 July 2019

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Article

Whole exome sequencing study of a Chinese concurrent cancer family

Yifa Yin, Shouxin Wu, Xincheng Zhao, Liyong Zou, Aihua Luo, Fei Deng, Mengyun Min, Lisha Jiang, Huimin Liu, Xiangbai Wu
Pages: 2619-2627
Published online on: 05 July 2019

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Article

Ursolic acid suppresses the biological function of osteosarcoma cells Retraction in /10.3892/ol.2023.13901

Yi Pei, Yueyan Zhang, Ke Zheng, Guanning Shang, Yuming Wang, Wei Wang, Enduo Qiu, Xiaojing Zhang
Pages: 2628-2638
Published online on: 04 July 2019

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Article

Sulforaphane‑induced epigenetic regulation of Nrf2 expression by DNA methyltransferase in human Caco‑2 cells

Jia‑Wei Zhou, Min Wang, Nuan‑Xin Sun, Ying Qing, Teng‑Fei Yin, Cui Li, Dong Wu
Pages: 2639-2647
Published online on: 05 July 2019

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Case Report

Rapid decline of Philadelphia‑positive metaphases after nilotinib treatment in a cml patient expressing a rare e14a3 bcr‑abl1 fusion transcript: A case report

Michele Massimino, Stefania Stella, Elena Tirrò, Maria Letizia Consoli, Maria Stella Pennisi, Adriana Puma, Silvia Rita Vitale, Chiara Romano, Valentina Zammit, Fabio Stagno, Francesco Di Raimondo, Livia Manzella
Pages: 2648-2653
Published online on: 04 July 2019

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Article Open Access

Lamin‑B1 is a senescence‑associated biomarker in clear‑cell renal cell carcinoma

Melissa Marie Radspieler, Mario Schindeldecker, Philipp Stenzel, Sebastian Försch, Katrin E. Tagscherer, Esther Herpel, Markus Hohenfellner, Gencay Hatiboglu, Wilfried Roth, Stephan Macher‑Goeppinger
Pages: 2654-2660
Published online on: 09 July 2019

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Expression patterns of programmed death‑1 and programmed death‑1 ligand‑1 on T cells in gastric cancer

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[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

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Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Article Open Access

Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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Article Open Access

D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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August-2026 Volume 32 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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