|
1
|
Bray F, Ferlay J, Soerjomataram I, Siegel
RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN
estimates of incidence and mortality worldwide for 36 cancers in
185 countries. CA Cancer J Clin. 68:394–424. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Nana-Sinkam SP and Powell CA: Molecular
biology of lung cancer: Diagnosis and management of lung cancer,
3rd ed: American College of Chest Physicians evidence-based
clinical practice guidelines. Chest. 143:e30S–e39S. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Solomon BJ, Mok T, Kim DW, Wu YL, Nakagawa
K, Mekhail T, Felip E, Cappuzzo F, Paolini J, Usari T, et al:
First-line crizotinib versus chemotherapy in ALK-positive lung
cancer. N Engl J Med. 371:2167–2177. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Mok TS: Personalized medicine in lung
cancer: What we need to know. Nat Rev Clin Oncol. 8:661–668. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Sharma SV, Bell DW, Settleman J and Haber
DA: Epidermal growth factor receptor mutations in lung cancer. Nat
Rev Cancer. 7:169–181. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
6
|
Shao Y, Liang B, Long F and Jiang SJ:
Diagnostic microRNA biomarker discovery for non-small-cell lung
cancer adenocarcinoma by integrative bioinformatics analysis.
Biomed Res Int. 2017:25630852017. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Wang LQ, Zhao LH and Qiao YZ:
Identification of potential therapeutic targets for lung cancer by
bioinformatics analysis. Mol Med Rep. 13:1975–1982. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Edgar R, Domrachev M and Lash AE: Gene
Expression Omnibus: NCBI gene expression and hybridization array
data repository. Nucleic Acids Res. 30:207–210. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Mitchell KA, Zingone A, Toulabi L,
Boeckelman J and Ryan BM: Comparative transcriptome profiling
reveals coding and noncoding RNA differences in NSCLC from African
Americans and European Americans. Clin Cancer Res. 23:7412–7425.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Marwitz S, Depner S, Dvornikov D, Merkle
R, Szczygieł M, Müller-Decker K, Lucarelli P, Wäsch M, Mairbäurl H,
Rabe KF, et al: Downregulation of the TGFβ pseudoreceptor BAMBI in
non-small cell lung cancer enhances TGFβ signaling and invasion.
Cancer Res. 76:3785–3801. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Barrett T, Wilhite SE, Ledoux P,
Evangelista C, Kim IF, Tomashevsky M, Marshall KA, Phillippy KH,
Sherman PM, Holko M, et al: NCBI GEO: Archive for functional
genomics data sets-update. Nucleic Acids Res. 41:D991–D995. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Huang DW, Sherman BT, Tan Q, Collins JR,
Alvord WG, Roayaei J, Stephens R, Baseler MW, Lane HC and Lempicki
RA: The DAVID Gene Functional Classification Tool: A novel
biological module-centric algorithm to functionally analyze large
gene lists. Genome Biol. 8:R1832007. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Kanehisa M: The KEGG database. Novartis
Found Symp. 247:91–103. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Szklarczyk D, Franceschini A, Wyder S,
Forslund K, Heller D, Huerta-Cepas J, Simonovic M, Roth A, Santos
A, Tsafou KP, et al: STRING v10: Protein-protein interaction
networks, integrated over the tree of life. Nucleic Acids Res.
43:D447–D452. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Shannon P, Markiel A, Ozier O, Baliga NS,
Wang JT, Ramage D, Amin N, Schwikowski B and Ideker T: Cytoscape: A
software environment for integrated models of biomolecular
interaction networks. Genome Res. 13:2498–2504. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Bader GD and Hogue CW: An automated method
for finding molecular complexes in large protein interaction
networks. BMC Bioinformatics. 4:22003. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Cerami E, Gao J, Dogrusoz U, Gross BE,
Sumer SO, Aksoy BA, Jacobsen A, Byrne CJ, Heuer ML, Larsson E, et
al: The cBio cancer genomics portal: An open platform for exploring
multidimensional cancer genomics data. Cancer Discov. 2:401–404.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Maere S, Heymans K and Kuiper M: BiNGO: A
Cytoscape plugin to assess overrepresentation of gene ontology
categories in biological networks. Bioinformatics. 21:3448–3449.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Nagy Á, Lánczky A, Menyhárt O and Győrffy
B: Validation of miRNA prognostic power in hepatocellular carcinoma
using expression data of independent datasets. Sci Rep. 8:92272018.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Li T, Gao X, Han L, Yu J and Li H:
Identification of hub genes with prognostic values in gastric
cancer by bioinformatics analysis. World J Surg Oncol. 16:1142018.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Bunn PA Jr: Karnofsky award 2016: A lung
cancer journey, 1973 to 2016. J Clin Oncol. 35:243–252. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Hirsch FR, Scagliotti GV, Mulshine JL,
Kwon R, Curran WJ Jr, Wu YL and Paz-Ares L: Lung cancer: Current
therapies and new targeted treatments. Lancet. 389:299–311. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Mendell JT: MicroRNAs: Critical regulators
of development, cellular physiology and malignancy. Cell Cycle.
4:1179–1184. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Xiao Y, Feng M, Ran H, Han X and Li X:
Identification of key differentially expressed genes associated
with non-small cell lung cancer by bioinformatics analyses. Mol Med
Rep. 17:6379–6386. 2018.PubMed/NCBI
|
|
25
|
Wen P, Chidanguro T, Shi Z, Gu H, Wang N,
Wang T, Li Y and Gao J: Identification of candidate biomarkers and
pathways associated with SCLC by bioinformatics analysis. Mol Med
Rep. 18:1538–1550. 2018.PubMed/NCBI
|
|
26
|
Tang Q, Zhang H, Kong M, Mao X and Cao X:
Hub genes and key pathways of non-small lung cancer identified
using bioinformatics. Oncol Lett. 16:2344–2354. 2018.PubMed/NCBI
|
|
27
|
Kato T, Daigo Y, Aragaki M, Ishikawa K,
Sato M and Kaji M: Overexpression of KIAA0101 predicts poor
prognosis in primary lung cancer patients. Lung Cancer. 75:110–118.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Man Y, Cao J, Jin S, Xu G, Pan B, Shang L,
Che D, Yu Q and Yu Y: Newly identified biomarkers for detecting
circulating tumor cells in lung adenocarcinoma. Tohoku J Exp Med.
234:29–40. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Kim DH, Park SE, Kim M, Ji YI, Kang MY,
Jung EH, Ko E, Kim Y, Kim S, Shim YM and Park J: A functional
single nucleotide polymorphism at the promoter region of cyclin A2
is associated with increased risk of colon, liver, and lung
cancers. Cancer. 117:4080–4091. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Li W, Zhang G, Li X, Wang X, Li Q, Hong L,
Shen Y, Zhao C, Gong X, Chen Y and Zhou J: Thyroid hormone receptor
interactor 13 (TRIP13) overexpression associated with tumor
progression and poor prognosis in lung adenocarcinoma. Biochem
Biophys Res Commun. 499:416–424. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Ma XP, Zhang W, Wu BQ and Qin J:
Correlations between mRNA levels of centrosomal protein 55 (CEP55)
and clinical features of patients with lung cancer. Med Sci Monit.
24:3093–3097. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Chiang IT, Wang WS, Liu HC, Yang ST, Tang
NY and Chung JG: Curcumin alters gene expression-associated DNA
damage, cell cycle, cell survival and cell migration and invasion
in NCI-H460 human lung cancer cells in vitro. Oncol Rep.
34:1853–1874. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Wan J, Zou S, Hu M, Zhu R, Xu J, Jiao Y
and Fan S: Thoc1 inhibits cell growth via induction of cell cycle
arrest and apoptosis in lung cancer cells. Mol Med Rep.
9:2321–2327. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wen J, Fu J, Zhang W and Guo M: Genetic
and epigenetic changes in lung carcinoma and their clinical
implications. Mod Pathol. 24:932–943. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Chun HK, Chung KS, Kim HC, Kang JE, Kang
MA, Kim JT, Choi EH, Jung KE, Kim MH, Song EY, et al: OIP5 is a
highly expressed potential therapeutic target for colorectal and
gastric cancers. BMB Rep. 43:349–354. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Gong M, Xu Y, Dong W, Guo G, Ni W, Wang Y,
Wang Y and An R: Expression of Opa interacting protein 5 (OIP5) is
associated with tumor stage and prognosis of clear cell renal cell
carcinoma. Acta Histochem. 115:810–815. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Tang J, Tang S, Liu J, Wu Q, Wan L and Xu
Q: Genetic risk of lung cancer associated with a single nucleotide
polymorphism from EXO1: A meta analysis. Int J Clin Exp Med.
8:11132–11138. 2015.PubMed/NCBI
|
|
38
|
Hsu NY, Wang HC, Wang CH, Chiu CF, Tseng
HC, Liang SY, Tsai CW, Lin CC and Bau DT: Lung cancer
susceptibility and genetic polymorphisms of Exo1 gene in Taiwan.
Anticancer Res. 29:725–730. 2009.PubMed/NCBI
|
|
39
|
Zhu K, Diao D, Dang C, Shi L, Wang J, Yan
R, Yuan D and Li K: Elevated KIAA0101 expression is a marker of
recurrence in human gastric cancer. Cancer Sci. 104:353–359. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Fan S and Li X, Tie L, Pan Y and Li X:
KIAA0101 is associated with human renal cell carcinoma
proliferation and migration induced by erythropoietin. Oncotarget.
7:13520–13537. 2016.PubMed/NCBI
|
|
41
|
Liu B, Qu J, Xu F, Guo Y, Wang Y, Yu H and
Qian B: MiR-195 suppresses non-small cell lung cancer by targeting
CHEK1. Oncotarget. 6:9445–9456. 2015.PubMed/NCBI
|
|
42
|
Inoue H, Kato T, Olugbile S, Tamura K,
Chung S, Miyamoto T, Matsuo Y, Salgia R, Nakamura Y and Park JH:
Effective growth-suppressive activity of maternal embryonic
leucine-zipper kinase (MELK) inhibitor against small cell lung
cancer. Oncotarget. 7:13621–13633. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Pitner MK, Taliaferro JM, Dalby KN and
Bartholomeusz C: MELK: A potential novel therapeutic target for
TNBC and other aggressive malignancies. Expert Opin Ther Targets.
21:849–859. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Zhang Q, Su R, Shan C, Gao C and Wu P:
Non-SMC condensin I complex, subunit G (NCAPG) is a novel mitotic
gene required for hepatocellular cancer cell proliferation and
migration. Oncol Res. 26:269–276. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Kim HE, Kim DG, Lee KJ, Son JG, Song MY,
Park YM, Kim JJ, Cho SW, Chi SG, Cheong HS, et al: Frequent
amplification of CENPF, GMNN and CDK13 genes in hepatocellular
carcinomas. PLoS One. 7:e432232012. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Aytes A, Mitrofanova A, Lefebvre C,
Alvarez MJ, Castillo-Martin M, Zheng T, Eastham JA, Gopalan A,
Pienta KJ, Shen MM, et al: Cross-species regulatory network
analysis identifies a synergistic interaction between FOXM1 and
CENPF that drives prostate cancer malignancy. Cancer Cell.
25:638–651. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Takagi K, Miki Y, Shibahara Y, Nakamura Y,
Ebata A, Watanabe M, Ishida T, Sasano H and Suzuki T: BUB1
immunolocalization in breast carcinoma: Its nuclear localization as
a potent prognostic factor of the patients. Horm Cancer. 4:92–102.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Li L, Xu DB, Zhao XL and Hao TY:
Combination analysis of Bub1 and Mad2 expression in endometrial
cancer: Act as a prognostic factor in endometrial cancer. Arch
Gynecol Obstet. 288:155–165. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Haruki N, Saito H, Harano T, Nomoto S and
Takahashi T, Osada H, Fujii Y and Takahashi T: Molecular analysis
of the mitotic checkpoint genes BUB1, BUBR1 and BUB3 in human lung
cancers. Cancer Lett. 162:201–205. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Yang J, Gao F, Xu X, Wang Y and Zhu S:
Targeting protein for Xenopus kinesin-like protein 2 knockdown
enhances radiation sensitivity of human lung squamous carcinoma
cell. Clin Exp Pharmacol Physiol. 44:1060–1068. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Schneider MA, Christopoulos P, Muley T,
Warth A, Klingmueller U, Thomas M, Herth FJ, Dienemann H, Mueller
NS, Theis F and Meister M: AURKA, DLGAP5, TPX2, KIF11 and CKAP5:
Five specific mitosis-associated genes correlate with poor
prognosis for non-small cell lung cancer patients. Int J Oncol.
50:365–372. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Zhang M, Yang D, Liu X, Liu Y, Liang J, He
H, Zhong K, Lin L, Tao G, Zhang C and Zhou J: Expression of Nusap1
in the surgical margins of hepatocellular carcinoma and its
association with early recurrence. Nan Fang Yi Ke Da Xue Xue Bao.
33:937–938, inside back cover. 2013.(In Chinese). PubMed/NCBI
|
|
53
|
Gordon CA, Gulzar ZG and Brooks JD: NUSAP1
expression is upregulated by loss of RB1 in prostate cancer cells.
Prostate. 75:517–526. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Zhao X, Zhou LL, Li X, Ni J, Chen P, Ma R,
Wu J and Feng J: Overexpression of KIF20A confers malignant
phenotype of lung adenocarcinoma by promoting cell proliferation
and inhibiting apoptosis. Cancer Med. 7:4678–4689. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Ma ZL, Zhang BJ, Wang DT, Li X, Wei JL,
Zhao BT, Jin Y, Li YL and Jin YX: Tanshinones suppress AURKA
through up-regulation of miR-32 expression in non-small cell lung
cancer. Oncotarget. 6:20111–20120. 2015.PubMed/NCBI
|
|
56
|
Lo Iacono M, Monica V, Saviozzi S, Ceppi
P, Bracco E, Papotti M and Scagliotti GV: Aurora Kinase A
expression is associated with lung cancer histological-subtypes and
with tumor de-differentiation. J Transl Med. 9:1002011. View Article : Google Scholar : PubMed/NCBI
|
