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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2019 Volume 18 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Mitochondrial oncobioenergetics of prostate tumorigenesis (Review)

Praveen Kumar Vayalil
Pages: 4367-4376
Published online on: 27 August 2019

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Review Open Access

Sonic Hedgehog signaling pathway as a potential target to inhibit the progression of hepatocellular carcinoma (Review)

Kuo‑Shyang Jeng, Chi‑Juei Jeng, Wen‑Juei Jeng, I‑Shyan Sheen, Shih‑Yun Li, Chuen‑Miin Leu, Yeou‑Guang Tsay, Chiung‑Fang Chang
Pages: 4377-4384
Published online on: 09 September 2019

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Review Open Access

Role of circular RNA in hematological malignancies (Review)

Mei Mei, Yingjun Wang, Zhaoming Li, Mingzhi Zhang
Pages: 4385-4392
Published online on: 10 September 2019

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Review Open Access

Molecular mechanisms of TUG1 in the proliferation, apoptosis, migration and invasion of cancer cells (Review)

Hui Zhou, Lina Sun, Fusheng Wan
Pages: 4393-4402
Published online on: 10 September 2019

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Article Open Access

Dauricine suppresses the growth of pancreatic cancer in vivo by modulating the Hedgehog signaling pathway

Ying‑Bo Zhang, Hong‑Xin Fei, Jia Guo, Xiao‑Jie Zhang, Shu‑Liang Wu, Li‑Li Zhong
Pages: 4403-4414
Published online on: 03 September 2019

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Case Report Open Access

CAR‑T 19 combined with reduced‑dose PD‑1 blockade therapy for treatment of refractory follicular lymphoma: A case report

Jia Wang, Qi Deng, Yan‑Yu Jiang, Rui Zhang, Hai‑Bo Zhu, Juan‑Xia Meng, Yu‑Ming Li
Pages: 4415-4420
Published online on: 27 August 2019

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Article Open Access

STAMBPL1 knockdown has antitumour effects on gastric cancer biological activities

Da‑Jun Yu, Jun Qian, Xin Jin, Jing Li, Chen‑Xu Guo, Xi‑Cheng Yue
Pages: 4421-4428
Published online on: 03 September 2019

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Article Open Access

Identification of key biomarkers and potential molecular mechanisms in lung cancer by bioinformatics analysis

Zhenhua Li, Meixiang Sang, Ziqiang Tian, Zhao Liu, Jian Lv, Fan Zhang, Baoen Shan
Pages: 4429-4440
Published online on: 04 September 2019

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Article Open Access

Survival‑related risk score of lung adenocarcinoma identified by weight gene co‑expression network analysis

He Wang, Di Lu, Xiguang Liu, Jianjun Jiang, Siyang Feng, Xiaoying Dong, Xiaoshun Shi, Hua Wu, Gang Xiong, Haofei Wang, Kaican Cai
Pages: 4441-4448
Published online on: 04 September 2019

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Article Open Access

Extracellular AGR3 regulates breast cancer cells migration via Src signaling

Joanna Obacz, Lucia Sommerova, Daria Sicari, Michal Durech, Tony Avril, Filippo Iuliano, Silvia Pastorekova, Roman Hrstka, Eric Chevet, Frederic Delom, Delphine Fessart
Pages: 4449-4456
Published online on: 10 September 2019

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Article Open Access

Phenotype of mesenchymal stem cells from patients with myelodyplastic syndrome maybe partly modulated by decitabine

Yanbin Pang, Suxia Geng, Hongyang Zhang, Peilong Lai, Pengjun Liao, Lingji Zeng, Zesheng Lu, Jianyu Weng, Xin Du
Pages: 4457-4466
Published online on: 03 September 2019

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Article Open Access

Plasma exosome‑encapsulated microRNA‑21 and microRNA‑92a are promising biomarkers for the prediction of peritoneal recurrence in patients with gastric cancer

Naruyoshi Soeda, Hisae Iinuma, Yusuke Suzuki, Daisuke Tsukahara, Hironori Midorikawa, Yuichi Igarashi, Yoshimasa Kumata, Masahiro Horikawa, Takashi Kiyokawa, Takeo Fukagawa, Ryoji Fukushima
Pages: 4467-4480
Published online on: 04 September 2019

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Article Open Access

Distinct expression pattern and prognostic values of pituitary tumor transforming gene family genes in non‑small cell lung cancer

Shaolong Yang, Xiaodi Wang, Jingxing Liu, Bisha Ding, Kairi Shi, Jing Chen, Weiyang Lou
Pages: 4481-4494
Published online on: 10 September 2019

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Article Open Access

Generation and identification of a thyroid cancer cell line with stable expression of CCDC67 and luciferase reporter genes

Lele Zhang, Longlong Wang, Mengyuan Lei, Runsheng Ma, Fangqin Yu, Chenguang Liu, Detao Yin
Pages: 4495-4502
Published online on: 10 September 2019

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Article Open Access

Integrated genomic and methylation profile analysis to identify candidate tumor marker genes in patients with colorectal cancer

Guojun Huang, Wang Cheng, Fu Xi
Pages: 4503-4514
Published online on: 04 September 2019

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Article Open Access

AKR1C1‑3, notably AKR1C3, are distinct biomarkers for liver cancer diagnosis and prognosis: Database mining in malignancies

Shou‑Feng Zhao, Shu‑Guo Wang, Zi‑Yun Zhao, Wen‑Li Li
Pages: 4515-4522
Published online on: 04 September 2019

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Article Open Access

Prognostic value of pre‑treatment peripheral blood markers in pancreatic ductal adenocarcinoma and their association with S100A4 expression in tumor tissue

Hua Li, Xiangdong Tian, Yong Xu, Yi Pan, Yubei Huang, Dejun Zhou, Zhenguo Song
Pages: 4523-4534
Published online on: 05 September 2019

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Article Open Access

Prognostic significance of mRNA expression of CASPs in gastric cancer

Zixiang Wang, Fubiao Ni, Fangyi Yu, Zhonghui Cui, Xiandong Zhu, Jicai Chen
Pages: 4535-4554
Published online on: 05 September 2019

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Article Open Access

Association between polymorphisms in EGFR and tumor response during cetuximab and oxaliplatin‑based combination therapy in metastatic colorectal cancer: Analysis of data from two clinical trials

Hiromichi Maeda, Shoichi Hazama, Shigeyoshi Iwamoto, Koji Oba, Ryouichi Tsunedomi, Naoko Okayama, Yutaka Suehiro, Takahiro Yamasaki, Yuki Nakagami, Nobuaki Suzuki, Hiroaki Nagano, Junichi Sakamoto, Hideyuki Mishima, Naoki Nagata
Pages: 4555-4562
Published online on: 29 August 2019

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Article Open Access

Pancreatoduodenectomy with portal vein resection favors the survival time of patients with pancreatic ductal adenocarcinoma: A propensity score matching analysis

Zhi‑Bo Xie, Ji Li, Ji‑Chun Gu, Chen Jin, Cai‑Feng Zou, De‑Liang Fu
Pages: 4563-4572
Published online on: 06 September 2019

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Article Open Access

Expression of ALDH1A1 and CD133 is associated with the prognosis and effect of different chemotherapeutic regimens in gastric cancer

Wan‑Ting Liu, Wen‑Bo Liu, Min Gao, Yi‑Yin Zhang, Kang‑Sheng Gu
Pages: 4573-4582
Published online on: 04 September 2019

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Article

Long non‑coding RNA transcribed from pseudogene PPIAP43 is associated with radiation sensitivity of small cell lung cancer cells Corrigendum in /10.3892/ol.2019.11202

Shilong Wang, Jinming Yu
Pages: 4583-4592
Published online on: 04 September 2019

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Article Open Access

Screening and authentication of molecular markers in malignant glioblastoma based on gene expression profiles

Yang‑Fan Zou, Ling‑Bing Meng, Zhao‑Kai He, Chen‑Hao Hu, Meng‑Jie Shan, Deng‑Yuan Wang, Xin Yu
Pages: 4593-4604
Published online on: 04 September 2019

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Article Open Access

Exploration of estrogen receptor‑associated hub genes and potential molecular mechanisms in non‑smoking females with lung adenocarcinoma using integrated bioinformatics analysis

Hao Wang, Zhihong Zhang, Ke Xu, Song Wei, Lailing Li, Lijun Wang
Pages: 4605-4612
Published online on: 10 September 2019

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Article Open Access

MicroRNA‑152 suppresses cisplatin resistance in A549 cells Corrigendum in /10.3892/ol.2020.11422

Wenfei Zhao, Hongyun Li, Shanshan Yang, Di Guo, Jing Chen, Shaoyi Miao, Yi Xin, Miaomiao Liang
Pages: 4613-4620
Published online on: 10 September 2019

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Article Open Access

miR-650 promotes non-small cell lung cancer cell proliferation and invasion by targeting ING4 through Wnt-1/β-catenin pathway

Xiangqin Tang, Yanjun Ding, Xiaoqing Wang, Xiuzhen Wang, Lin Zhao, Hongmei Bi
Pages: 4621-4628
Published online on: 04 September 2019

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Article Open Access

NRP‑1 and KDR polymorphisms are associated with survival time in patients with advanced gastric cancer

Yue‑Jian Zhuo, Yu Shi, Tao Wu
Pages: 4629-4638
Published online on: 10 September 2019

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Article Open Access

Long non‑coding RNA GATA6‑AS inhibits gastric cancer cell proliferation by downregulating microRNA‑25‑3p

Dingyun Li, Ting Wang, Jiajun Lai, Tao Zhang, Xiaofeng Zhu, Deqiang Zeng, Zhiwei Hu
Pages: 4639-4644
Published online on: 04 September 2019

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Article Open Access

Cancer‑associated fibroblast stimulates cancer cell invasion in an interleukin‑1 receptor (IL‑1R)‑dependent manner

Xianglan Zhang, Young Sun Hwang
Pages: 4645-4650
Published online on: 27 August 2019

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Article Open Access

Regulating the CCNB1 gene can affect cell proliferation and apoptosis in pituitary adenomas and activate epithelial‑to‑mesenchymal transition

Bin Li, Hai‑Bo Zhu, Gui‑Dong Song, Jian‑Hua Cheng, Chu‑Zhong Li, Ya‑Zhuo Zhang, Peng Zhao
Pages: 4651-4658
Published online on: 10 September 2019

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Article Open Access

Ubiquitin ligase RNF5 serves an important role in the development of human glioma

Yong Gao, Chengmin Xuan, Mingwei Jin, Qi An, Baobiao Zhuo, Xincheng Chen, Lei Wang, Yuan Wang, Qingzeng Sun, Yingchun Shi
Pages: 4659-4666
Published online on: 04 September 2019

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Article Open Access

Screening and identification of key biomarkers in adrenocortical carcinoma based on bioinformatics analysis

Zengmiao Xing, Zuojie Luo, Haiyan Yang, Zhenxing Huang, Xinghuan Liang
Pages: 4667-4676
Published online on: 06 September 2019

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Article Open Access

Construction of a model to predict the prognosis of patients with cholangiocarcinoma using alternative splicing events

Hua‑Yu Wu, Yi Wei, Li‑Min Liu, Zhong‑Biao Chen, Qi‑Ping Hu, Shang‑Ling Pan
Pages: 4677-4690
Published online on: 10 September 2019

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Article Open Access

High expression level of peptidylprolyl isomerase A is correlated with poor prognosis of liver hepatocellular carcinoma

Shilong Wang, Minghuan Li, Ligang Xing, Jinming Yu
Pages: 4691-4702
Published online on: 10 September 2019

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Article Open Access

Preoperative color Doppler ultrasonography predicts early recurrence in AFP‑positive hepatocellular carcinoma

Miao Chen, Duo Wang, Yuan Zhao, Dan‑Mei Lu, Hong‑Xue Li, Jun‑Jie Liu, Hang Li
Pages: 4703-4711
Published online on: 09 September 2019

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Article Open Access

STMN1 accumulation is associated with dysplastic and neoplastic lesions in patients with ulcerative colitis

Katsuya Osone, Takehiko Yokobori, Chika Katayama, Ryo Takahashi, Ryuji Kato, Hironori Tatsuski, Takahiro Takada, Reina Yajima, Yoko Motegi, Hiroomi Ogawa, Takaaki Fujii, Hitoshi Ojima, Junichi Nakamura, Takashi Yao, Ken Shirabe, Hiroyuki Kuwano
Pages: 4712-4718
Published online on: 05 September 2019

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Article Open Access

LncRNA‑AWPPH activates TGF‑β1 in colorectal adenocarcinoma

Chengcong Liu, Bo Han, Jianjun Xin, Cheng Yang
Pages: 4719-4725
Published online on: 04 September 2019

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Article Open Access

Long non‑coding RNA small nucleolar RNA host gene 7 is upregulated and promotes cell proliferation in thyroid cancer

Li Chen, Jing Zhu, Ling‑Jie Zhang
Pages: 4726-4734
Published online on: 27 August 2019

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Article Open Access

Artesunate and sorafenib: Combinatorial inhibition of liver cancer cell growth

Hao Li, Kanghe Xu, Guangzhe Pian, Shu Sun
Pages: 4735-4743
Published online on: 05 September 2019

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Article Open Access

Prognostic value of insulin‑like growth factor 2 mRNA‑binding protein 3 and vascular endothelial growth factor‑A in patients with primary non‑small‑cell lung cancer

Jiannan Liu, Ying Liu, Wenjing Gong, Xiangshuo Kong, Congcong Wang, Shuhua Wang, Aina Liu
Pages: 4744-4752
Published online on: 10 September 2019

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Article Open Access

Identification and performance evaluation of housekeeping genes for microRNA expression normalization by reverse transcription‑quantitative PCR using liquid‑based cervical cytology samples

Rhafaela Lima Causin, Danielle Pessôa‑Pereira, Karen Cristina Borba Souza, Adriane Feijó Evangelista, Rui Manuel Vieira Reis, José Humberto Tavares Guerreiro Fregnani, Márcia Maria Chiquitelli Marques
Pages: 4753-4761
Published online on: 06 September 2019

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Article Open Access

Comprehensive analysis of genomic alterations detected by next‑generation sequencing‑based tissue and circulating tumor DNA assays in Chinese patients with non‑small cell lung cancer

Hua Yang, Junjie Zhang, Lemeng Zhang, Xiaoping Wen, Yongzhong Luo, Dingquan Yao, Tianli Cheng, Huanqing Cheng, Huina Wang, Feng Lou, Jing Guo, Xiayuan Liang, Shanbo Cao, Jianhua Chen
Pages: 4762-4770
Published online on: 03 September 2019

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Article Open Access

Downregulation of FOXP3 in neutrophils by IL‑8 promotes the progression of oral squamous cell carcinoma

Chuangui Zeng, Hai Kuang, Wan Fan, Xueru Chen, Tao Yu, Qinchao Tang, Zhuoqian Zhou, Feixin Liang
Pages: 4771-4777
Published online on: 09 September 2019

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Article Open Access

Identification of cancer/testis antigen 2 gene as a potential hepatocellular carcinoma therapeutic target by hub gene screening with topological analysis

Jinwei Liu, Zhaojin Yu, Mingli Sun, Qianqian Liu, Minjie Wei, Hua Gao
Pages: 4778-4788
Published online on: 05 September 2019

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Article Open Access

Expression of CREPT is associated with poor prognosis of patients with renal cell carcinoma

Huaqi Yin, Qingfei Cao, Haiyue Zhao, Shenheng Wang, Weinan Chen, Xiaowei Zhang, Zhijie Chang, Tao Xu, Xiongjun Ye
Pages: 4789-4797
Published online on: 09 September 2019

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Article Open Access

Cancer‑related long noncoding RNAs show aberrant expression profiles and competing endogenous RNA potential in esophageal adenocarcinoma

Yang Yu, Xingxing Chen, Shundong Cang
Pages: 4798-4808
Published online on: 05 September 2019

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Article Open Access

Knockdown of neuron‑specific enolase suppresses the proliferation and migration of NCI‑H209 cells

Xia Liu, Shousheng Liu, Juan Fu, Jinsheng Huang, Chengyin Weng, Xisheng Fang, Mingmei Guan, Yong Wu, Lin Yang, Guolong Liu
Pages: 4809-4815
Published online on: 04 September 2019

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Article Open Access

Identification and meta‑analysis of copy number variation‑driven circadian clock genes for colorectal cancer

Wenliang Yuan, Li Liu, Cai Wei, Xiaobo Li, Dan Sun, Chaoxu Dai, Sicong Li, Sihua Peng, Linhua Jiang
Pages: 4816-4824
Published online on: 09 September 2019

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Article Open Access

Primary impact of Gli1 on radioresistance in esophageal cancer

Fei Yao, Jinjing Yu, Yulin He, Jiaqi Liu, Huan Li, Qun Liu, Hui Long, Qingming Wu
Pages: 4825-4833
Published online on: 10 September 2019

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Article Open Access

Characteristics of fecal gut microbiota in patients with colorectal cancer at different stages and different sites

Qinsong Sheng, Haixia Du, Xiaofei Cheng, Xiaobin Cheng, Yunning Tang, Lelin Pan, Qunmin Wang, Jianjiang Lin
Pages: 4834-4844
Published online on: 10 September 2019

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Article Open Access

Prognostic values of transketolase family genes in ovarian cancer

Menghuang Zhao, Miaomiao Ye, Junhan Zhou, Xueqiong Zhu
Pages: 4845-4857
Published online on: 06 September 2019

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Article Open Access

Anticancer effect of XAV939 is observed by inhibiting lactose dehydrogenase A in a 3‑dimensional culture of colorectal cancer cells

Dahee Kim, Byumseok Koh, Kwang Rok Kim, Ki Young Kim, Won Hoon Jung, Hi Youn Kim, Sungsub Kim, Sang Dal Rhee
Pages: 4858-4864
Published online on: 05 September 2019

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Article Open Access

Surgery in patients with small cell lung cancer: A period propensity score matching analysis of the Seer database, 2010‑2015

Xiaojun Du, Dan Tian, Langbo Liu, Zhongben Tang, Jiarong Xiao, Wen Liu, Shizhang Yuan, Xi Cao, Haiyu Zhou, Jian Zhang
Pages: 4865-4881
Published online on: 03 September 2019

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Article Open Access

Diagnostic and prognostic value of microRNA‑193b in patients with glioma and its effect on tumor progression

Mingtao Zhu, Wei Zhao, Hui Zhao, Jing Zhang
Pages: 4882-4890
Published online on: 06 September 2019

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Article Open Access

Prognostic value and association of Lauren classification with VEGF and VEGFR‑2 expression in gastric cancer

Xiayi Li, Xueru Zhu, Yiwei Wang, Ruifen Wang, Lifeng Wang, Mei‑Ling Zhu, Leizhen Zheng
Pages: 4891-4899
Published online on: 06 September 2019

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Article Open Access

High expression of AGBL2 is a novel prognostic factor of adverse outcome in patients with ovarian carcinoma

Wei‑Peng He, Li‑Li Wang
Pages: 4900-4906
Published online on: 09 September 2019

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Article Open Access

A three-gene novel predictor for improving the prognosis of cervical cancer

Ting-Ting Ding, Hu Ma, Ji-Hong Feng
Pages: 4907-4915
Published online on: 05 September 2019

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Article Open Access

Effects of radioactive 125I on apoptosis of HGC-27 gastric cancer cells

Yong Yang, Aifei Chen, Jun Ma, Aiping Wu, Fazhen Xu
Pages: 4916-4922
Published online on: 09 September 2019

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Article

Impact of spheroid culture on molecular and functional characteristics of bladder cancer cell lines

Takahiro Yoshida, Nikolai A. Sopko, Max Kates, Xiaopu Liu, Gregory Joice, David J. Mcconkey, Trinity J. Bivalacqua
Pages: 4923-4929
Published online on: 29 August 2019

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Article

MicroRNA‑31 is a potential biomarker for screening B‑lymphoblastic leukemia in children

Yan Zhang, Xin Li, Liping Bai, Li Li, Danhong Li, Xue Ding, Bo Wang, Chengwei Li
Pages: 4930-4935
Published online on: 10 September 2019

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Article

HDGF and PRKCA upregulation is associated with a poor prognosis in patients with lung adenocarcinoma

Honghong Jiang, Qiaofen Fu, Xin Song, Chunlei Ge, Ruilei Li, Zhen Li, Baozhen Zeng, Chunyan Li, Ying Wang, Yuanbo Xue, Rongcheng Luo, Weiyi Fang
Pages: 4936-4946
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BNP as a marker for early prediction of anthracycline‑induced cardiotoxicity in patients with breast cancer

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Qinglai Bian, Jiaxu Chen, Wenqi Qiu, Chenxi Peng, Meifang Song, Xuebin Sun, Yueyun Liu, Fengmin Ding, Jianbei Chen, Liqing Zhang
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[Corrigendum] Isolation of circulating tumor cells in patients undergoing surgery for esophageal cancer and a specific confirmation method

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Article Number: 35
Published online on: 17 November 2025

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TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Review Open Access

Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Case Report Open Access

Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Article Open Access

Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Review Open Access

Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Review Open Access

Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Article Open Access

Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Review Open Access

Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Article Open Access

Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Article Open Access

Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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Article Open Access

CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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