|
1
|
Bray F, Ferlay J, Soerjomataram I, Siegel
RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN
estimates of incidence and mortality worldwide for 36 cancers in
185 countries. CA Cancer J Clin. 68:394–424. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lagergren J, Smyth E, Cunningham D and
Lagergren P: Oesophageal cancer. Lancet. 390:2383–2396. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Sohda M and Kuwano H: Current status and
future prospects for esophageal cancer treatment. Ann Thorac
Cardiovasc Surg. 23:1–11. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Abnet CC, Arnold M and Wei WQ:
Epidemiology of esophageal squamous cell carcinoma.
Gastroenterology. 154:360–373. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Lin Y, Totsuka Y, He Y, Kikuchi S, Qiao Y,
Ueda J, Wei W, Inoue M and Tanaka H: Epidemiology of esophageal
cancer in Japan and China. J Epidemiol. 23:233–242. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Keditsu KK, Jiwnani S, Karimundackal G and
Pramesh CS: Multimodality management of esophageal cancer. Indian J
Surg Oncol. 4:96–104. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Januszewicz W and Fitzgerald RC: Early
detection and therapeutics. Mol Oncol. 13:599–613. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Bird-Lieberman EL and Fitzgerald RC: Early
diagnosis of oesophageal cancer. Br J Cancer. 101:1–6. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Guo X, Duan Y, Ye X, Hu L, Xu T, Tong L
and Yu M: Stable silencing of dll4 gene suppresses the growth and
metastasis of esophagus cancer cells by attenuating Akt
phosphorylation. Oncol Rep. 40:495–503. 2018.PubMed/NCBI
|
|
10
|
Alexandre L, Long E and Beales IL:
Pathophysiological mechanisms linking obesity and esophageal
adenocarcinoma. World J Gastrointest Pathophysiol. 5:534–549. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Qian X, Tan C, Wang F, Yang B, Ge Y, Guan
Z and Cai J: Esophageal cancer stem cells and implications for
future therapeutics. Onco Targets Ther. 9:2247–2254.
2016.PubMed/NCBI
|
|
12
|
Lou F, Sima CS, Adusumilli PS, Bains MS,
Sarkaria IS, Rusch VW and Rizk NP: Esophageal cancer recurrence
patterns and implications for surveillance. J Thoracic Oncol.
8:1558–1562. 2013. View Article : Google Scholar
|
|
13
|
Domper Arnal MJ, Ferrandez Arenas A and
Lanas Arbeloa A: Esophageal cancer: Risk factors, screening and
endoscopic treatment in Western and Eastern countries. World J
Gastroenterol. 21:7933–7943. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Wu SG, Xie WH, Zhang ZQ, Sun JY, Li FY,
Lin HX, Yong Bao and He ZY: Surgery combined with radiotherapy
improved survival in metastatic esophageal cancer in a surveillance
epidemiology and end results population-based study. Sci Rep.
6:282802016. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Ordu AD, Nieder C, Geinitz H, Kup PG,
Deymann LF, Scherer V, Combs SE and Fakhrian K: Radio(chemo)therapy
for locally advanced squamous cell carcinoma of the esophagus:
Long-term outcome. Strahlenther Onkol. 191:153–160. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Malhotra A, Sharma U, Puhan S, Chandra
Bandari N, Kharb A, Arifa PP, Thakur L, Prakash H, Vasquez KM and
Jain A: Stabilization of miRNAs in esophageal cancer contributes to
radioresistance and limits efficacy of therapy. Biochimie.
156:148–157. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Hu YT, Li BF, Zhang PJ, Wu D, Li YY, Li
ZW, Shen L, Dong B, Gao J and Zhu X: Dbx2 exhibits a
tumor-promoting function in hepatocellular carcinoma cell lines via
regulating Shh-Gli1 signaling. World J Gastroenterol. 25:923–940.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Liu X, Zhao T, Bai X, Li M, Ren J, Wang M,
Xu R, Zhang S, Li H, Hu Y, et al: LOC101930370/MiR-1471 axis
modulates the hedgehog signaling pathway in breast cancer. Cell
Physiol Biochem. 48:1139–1150. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Islam SS, Mokhtari RB, Noman AS, Uddin M,
Rahman MZ, Azadi MA, Zlotta A, van der Kwast T, Yeger H and Farhat
WA: Sonic hedgehog (Shh) signaling promotes tumorigenicity and
stemness via activation of epithelial-to-mesenchymal transition
(EMT) in bladder cancer. Mol Carcinog. 55:537–551. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Wang Z, Jiang J, Qin T, Xiao Y and Han L:
EIF5A regulates proliferation and chemoresistance in pancreatic
cancer through the SHH signalling pathway. J Cell Mol Med.
23:2678–2688. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Chen J, Wu QM, Long H, Zhang H and Chen
JH: P162 enhances the radiosensitivity of esophageal cancer Eca109
cells by inhibiting Gli-1, the transcription factor of Hedgehog
signaling pathway. World Chin J Digestology. 22:615–623. 2014.
|
|
22
|
Lin Y, Totsuka Y, Shan B, Wang C, Wei W,
Qiao Y, Kikuchi S, Inoue M, Tanaka H and He Y: Esophageal cancer in
high-risk areas of China: Research progress and challenges. Ann
Epidemiol. 27:215–221. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Xi M and Lin SH: Recent advances in
intensity modulated radiotherapy and proton therapy for esophageal
cancer. Expert Rev Anticancer Ther. 17:635–646. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Zhang YY, Wang LB, Zhao Q, Li G, Gong SL
and Dong LH: Advanced research on relationship between tumor
microenvironment and radiosensitivity of tumor cells. J Jilin
University (Medical Edition). 42:1038–1044. 2016.
|
|
25
|
Shen C, Chen F, Wang H, Li G, Yu C, Wang X
and Wen Z: The Pinx1 gene downregulates telomerase and inhibits
proliferation of CD133+ cancer stem cells isolated from a
nasopharyngeal carcinoma cell line by regulating Trfs and
Mad1/C-Myc/p53 pathways. Cell Physiol Biochem. 49:282–294. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Sharma BK, Manglik V, O'Connell M,
Weeraratna A, McCarron EC, Broussard JN, Divito KA,
Simbulan-Rosenthal CM, Rosenthal DS and Zapas JL: Clonal dominance
of CD133+ subset population as risk factor in tumor progression and
disease recurrence of human cutaneous melanoma. Int J Oncol.
41:1570–1576. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Siersema PD and Van Hillegersberg R:
Treatment of locally advanced esophageal cancer with surgery and
chemoradiation. Curr Opin Gastroenterol. 24:535–540. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Koike R, Nishimura Y, Nakamatsu K,
Kanamori S and Shibata T: Concurrent chemoradiotherapy for
esophageal cancer with malignant fistula. Int J Radiat Oncol Biol
Phys. 70:1418–1422. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Zhou Y, Chu L, Wang Q, Dai W, Zhang X,
Chen J, Li L, Ding P, Zhang L, Gu H, et al: CD59 is a potential
biomarker of esophageal squamous cell carcinoma radioresistance by
affecting DNA repair. Cell Death Dis. 9:8872018. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Pan S, Sun Y, Sui D, Yang T, Fu S, Wang J,
Hui B, Xi R, He C and Zhang X: Lobaplatin promotes
radiosensitivity, induces apoptosis, attenuates cancer stemness and
inhibits proliferation through PI3K/AKT pathway in esophageal
squamous cell carcinoma. Biomed Pharmacother. 102:567–574. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Park M, Yoon HJ, Kang MC, Kwon J and Lee
HW: MiR-338-5p enhances the radiosensitivity of esophageal squamous
cell carcinoma by inducing apoptosis through targeting survivin.
Sci Rep. 7:109322017. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zang C, Zhao F, Hua L and Pu Y: The
miR-199a-3p regulates the radioresistance of esophageal cancer
cells via targeting the AK4 gene. Cancer Cell Int. 18:1862018.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Zhang H, Hua Y, Jiang Z, Yue J, Shi M,
Zhen X, Zhang X, Yang L, Zhou R and Wu S: Cancer-associated
fibroblast-promoted LncRNA DNM3OS confers radioresistance by
regulating DNA damage response in esophageal squamous cell
carcinoma. Clin Cancer Res. 25:1989–2000. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Li Z, Zhou Y, Tu B, Bu Y, Liu A and Kong
J: Long noncoding RNA MALAT1 affects the efficacy of radiotherapy
for esophageal squamous cell carcinoma by regulating Cks1
expression. J Oral Pathol Med. 46:583–590. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Xie SY, Li G, Han C, Yu YY and Li N: RKIP
reduction enhances radioresistance by activating the Shh signaling
pathway in non-small-cell lung cancer. Onco Targets Ther.
10:5605–5619. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Wu G, Chen G, Zhou J, Zhu H, Chu J and
Zhang F: Liriodenine enhances radiosensitivity in esophageal cancer
ECA109 cells by inducing apoptosis and G2/M arrest. Oncol Lett.
16:5020–5026. 2018.PubMed/NCBI
|
|
37
|
Hu L, Lin X, Lu H, Chen B and Bai Y: An
overview of hedgehog signaling in fibrosis. Mol Pharmacol.
87:174–182. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Zhu SL, Luo MQ, Peng WX, Li QX, Feng ZY,
Li ZX, Wang MX, Feng XX, Liu F and Huang JL: Sonic hedgehog
signalling pathway regulates apoptosis through Smo protein in human
umbilical vein endothelial cells. Rheumatology (Oxford).
54:1093–1102. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Tanaka T, Arai M, Minemura S, Oyamada A,
Saito K, Jiang X, Tsuboi M, Sazuka S, Maruoka D, Matsumura T, et
al: Expression level of sonic hedgehog correlated with the speed of
gastric mucosa regeneration in artificial gastric ulcers. J
Gastroenterol Hepatol. 29:736–741. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Wadhwa R, Wang X, Baladandayuthapani V,
Liu B, Shiozaki H, Shimodaira Y, Lin Q, Elimova E, Hofstetter WL,
Swisher SG, et al: Nuclear expression of Gli-1 is predictive of
pathologic complete response to chemoradiation in trimodality
treated oesophageal cancer patients. Br J Cancer. 117:648–655.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Briscoe J and Thérond PP: The mechanisms
of hedgehog signalling and its roles in development and disease.
Nat Rev Mol Cell Biol. 14:416–429. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Miele E, Po A, Begalli F, Antonucci L,
Mastronuzzi A, Marras CE, Carai A, Cucchi D, Abballe L, Besharat
ZM, et al: b-arrestin1-mediated acetylation of Gli1 regulates
Hedgehog/Gli signaling and modulates self-renewal of SHH
medulloblastoma cancer stem cells. BMC Cancer. 17:4882017.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Wei L and Xu Z: Cross-signaling among
phosphinositide-3 kinase, mitogen-activated protein kinase and
sonic hedgehog pathways exists in esophageal cancer. Int J Cancer.
129:275–284. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Huang C, Lu H, Li J, Xie X, Fan L, Wang D,
Tan W, Wang Y, Lin Z and Yao T: SOX2 regulates radioresistance in
cervical cancer via the hedgehog signaling pathway. Gynecol Oncol.
151:533–541. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Mori Y, Okumura T, Tsunoda S, Sakai Y and
Shimada Y: Gli-1 expression is associated with lymph node
metastasis and tumor progression in esophageal squamous cell
carcinoma. Oncology. 70:378–389. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Cheng J, Gao J and Tao K: Prognostic role
of Gli1 expression in solid malignancies: A meta-analysis. Sci Rep.
6:221842016. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Zhu W, You Z, Li T, Yu C, Tao G, Hu M and
Chen X: Correlation of hedgehog signal activation with
chemoradiotherapy sensitivity and survival in esophageal squamous
cell carcinomas. Jpn J Clin Oncol. 41:386–393. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Teichman J, Dodbiba L, Thai H, Fleet A,
Morey T, Liu L, McGregor M, Cheng D, Chen Z, Darling G, et al:
Hedgehog inhibition mediates radiation sensitivity in mouse
xenograft models of human esophageal adenocarcinoma. PLoS One.
13:e01948092018. View Article : Google Scholar : PubMed/NCBI
|
