|
1
|
Espey DK, Wu XC, Swan J, Wiggins C, Jim
MA, Ward E, Wingo PA, Howe HL, Ries LA, Miller BA, et al: Annual
report to the nation on the status of cancer, 1975–2004, featuring
cancer in American Indians and Alaska Natives. Cancer.
110:2119–2152. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Parkin DM, Srivatanakul P, Khlat M,
Chenvidhya D, Chotiwan P, Insiripong S, L'Abbé KA and Wild CP:
Liver cancer in Thailand. I. A case-control study of
cholangiocarcinoma. Int J Cancer. 48:323–328. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Dhanasekaran R, Hemming AW, Zendejas I,
George T, Nelson DR, Soldevila-Pico C, Firpi RJ, Morelli G, Clark V
and Cabrera R: Treatment outcomes and prognostic factors of
intrahepatic cholangiocarcinoma. Oncol Rep. 29:1259–1267. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Lieser MJ, Barry MK, Rowland C, Ilstrup DM
and Nagorney DM: Surgical management of intrahepatic
cholangiocarcinoma: A 31 year experience. J Hepatobiliary Pancreat
Surg. 5:41–47. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Ma KL, Ruan XZ, Powis SH, Chen Y, Moorhead
JF and Varghese Z: Inflammatory stress exacerbates lipid
accumulation in hepatic cells and fatty livers of apolipoprotein E
knockout mice. Hepatology. 48:770–781. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Rao RK and Samak G: Bile duct epithelial
tight junctions and barrier function. Tissue Barriers.
1:e257182013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Hofmann AF: The enterohepatic circulation
of bile acids in mammals: Form and functions. Front Biosci
(Landmark Ed). 14:2584–2598. 2009. View
Article : Google Scholar : PubMed/NCBI
|
|
8
|
Tabibian JH, Masyuk AI, Masyuk TV, O'Hara
SP and LaRusso NF: Physiology of cholangiocytes. Compr Physiol.
3:541–565. 2013.PubMed/NCBI
|
|
9
|
Nachtergaele S, Mydock LK, Krishnan K,
Rammohan J, Schlesinger PH, Covey DF and Rohatgi R: Oxysterols are
allosteric activators of the oncoprotein smoothened. Nat Chem Biol.
8:211–220. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Olkkonen VM, Béaslas O and Nissilä E:
Oxysterols and their cellular effectors. Biomolecules. 2:76–103.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Zeng Y, Peng Y, Tang K, Wang YQ, Zhao ZY,
Wei XY and Xu XL: Dihydromyricetin ameliorates foam cell formation
via LXRα-ABCA1/ABCG1-dependent cholesterol efflux in macrophages.
Biomed Pharmacother. 101:543–552. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Li Y, Jiang B, Liang P, Tong Z, Liu M, Lv
Q, Liu Y, Liu X, Tang Y and Xiao X: Nucleolin protects macrophages
from oxLDL-induced foam cell formation through up-regulating ABCA1
expression. Biochem Biophys Res Commun. 486:364–371. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Wang X, Collins HL, Ranalletta M, Fuki IV,
Billheimer JT, Rothblat GH, Tall AR and Rader DJ: Macrophage ABCA1
and ABCG1, but not SR-BI, promote macrophage reverse cholesterol
transport in vivo. J Clin Invest. 117:2216–2224. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Basso F, Freeman L, Knapper CL, Remaley A,
Stonik J, Neufeld EB, Tansey T, Amar MJ, Fruchart-Najib J, Duverger
N, et al: Role of the hepatic ABCA1 transporter in modulating
intrahepatic cholesterol and plasma HDL cholesterol concentrations.
J Lipid Res. 44:296–302. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Feng B and Tabas I: ABCA1-mediated
cholesterol efflux is defective in free cholesterol-loaded
macrophages. Mechanism involves enhanced ABCA1 degradation in a
process requiring full NPC1 activity. J Biol Chem. 277:43271–43280.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Lee BH, Taylor MG, Robinet P, Smith JD,
Schweitzer J, Sehayek E, Falzarano SM, Magi-Galluzzi C, Klein EA
and Ting AH: Dysregulation of cholesterol homeostasis in human
prostate cancer through loss of ABCA1. Cancer Res. 73:1211–1218.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Argmann CA, Edwards JY, Sawyez CG, O'Neil
CH, Hegele RA, Pickering JG and Huff MW: Regulation of macrophage
cholesterol efflux through hydroxymethylglutaryl-CoA reductase
inhibition: A role for RhoA in ABCA1-mediated cholesterol efflux. J
Biol Chem. 280:22212–22221. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Miller T, Yang F, Wise CE, Meng F,
Priester S, Munshi MK, Guerrier M, Dostal DE and Glaser SS:
Simvastatin stimulates apoptosis in cholangiocarcinoma by
inhibition of Rac1 activity. Dig Liver Dis. 43:395–403. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Kamigaki M, Sasaki T, Serikawa M, Inoue M,
Kobayashi K, Itsuki H, Minami T, Yukutake M, Okazaki A, Ishigaki T,
et al: Statins induce apoptosis and inhibit proliferation in
cholangiocarcinoma cells. Int J Oncol. 39:561–568. 2011.PubMed/NCBI
|
|
20
|
Lee J, Hong EM, Jang JA, Park SW, Koh DH,
Choi MH, Jang HJ and Kae SH: Simvastatin induces apoposis and
suppresses insulin-like growth factor 1 receptor in bile duct
cancer cells. Gut Liver. 10:310–317. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Sun Y, Sukumaran P, Varma A, Derry S,
Sahmoun AE and Singh B: Cholesterol-induced activation of TRPM7
regulate cell proliferation, migration, and viability of human
prostate cells. Biochimica Biophys Acta. 1843:1839–1850. 2014.
View Article : Google Scholar
|
|
22
|
Yanae M, Tsubaki M, Satou T, Itoh T, Iman
M, Yamazoe Y and Nishida S: Statin-induced apoptosis via the
suppression of ERK1/2 and Akt activation by inhibition of the
geranylgeranyl-pyrophosphate biosynthesis in glioblastoma. J Exp
Clin Cancer Res. 30:742011. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Lyu J, Imachi H, Iwama H, Zhang H and
Murao K: Insulin-like growth factor 1 regulates the expression of
ATP-binding cassette Transporter A1 in pancreatic beta cells. Horm
Metab Res. 48:338–344. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Dong F, Mo Z, Eid W, Courtney KC and Zha
X: Akt Inhibition promotes ABCA1-mediated cholesterol efflux to
ApoA-I through suppressing mTORC1. PLoS One. 9:e1137892014.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Sripa B, Leungwattanawanit S, Nitta T,
Wongkham C, Bhudhisawasdi V, Puapairoj A, Sripa C and Miwa M:
Establishment and characterization of an opisthorchiasis-associated
cholangiocarcinoma cell line (KKU-100). World J Gastroenterol.
11:3392–3397. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Sirisinha S, Tengchaisri T, Boonpucknavig
S, Prempracha N, Ratanarapee S and Pausawasdi A: Establishment and
characterization of a cholangiocarcinoma cell line from a thai
patient with intrahepatic bile duct cancer. Asian Pac J Allergy
Immunol. 9:153–157. 1991.PubMed/NCBI
|
|
27
|
Rattanasinganchan P, Leelawat K,
Treepongkaruna SA, Tocharoentanaphol C, Subwongcharoen S,
Suthiphongchai T and Tohtong R: Establishment and characterization
of a cholangiocarcinoma cell line (RMCCA-1) from a thai patient.
World J Gastroenterol. 12:6500–6506. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Sankaranarayanan S, Kellner-Weibel G, de
la Llera-Moya M, Phillips MC, Asztalos BF, Bittman R and Rothblat
GH: A sensitive assay for ABCA1-mediated cholesterol efflux using
BODIPY-cholesterol. J Lipid Res. 52:2332–2340. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Dos Santos CR, Domingues G, Matias I,
Matos J, Fonseca I, de Almeida JM and Dias S: LDL-cholesterol
signaling induces breast cancer proliferation and invasion. Lipids
Health Dis. 13:162014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Pussinen PJ, Karten B, Wintersperger A,
Reicher H, McLean M, Malle E and Sattler W: The human breast
carcinoma cell line HBL-100 acquires exogenous cholesterol from
high-density lipoprotein via CLA-1 (CD-36 and LIMPII analogous
1)-mediated selective cholesteryl ester uptake. Biochem J.
349:559–566. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Lim SC, Parajuli KR, Duong HQ, Choi JE and
Han SI: Cholesterol induces autophagic and apoptotic death in
gastric carcinoma cells. Int J Oncol. 44:805–811. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Huang YN, Lin CI, Liao H, Liu CY, Chen YH,
Chiu WC and Lin SH: Cholesterol overload induces apoptosis in
SH-SY5Y human neuroblastoma cells through the up regulation of
flotillin-2 in the lipid raft and the activation of BDNF/Trkb
signaling. Neuroscience. 328:201–209. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Yao PM and Tabas I: Free cholesterol
loading of macrophages induces apoptosis involving the fas pathway.
J Biol Chem. 275:23807–23813. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Lin CJ, Liao WC, Chen YA, Lin HJ, Feng CL,
Lin CL, Lin YJ, Kao MC, Huang MZ, Lai CH and Kao CH: Statin therapy
is associated with reduced risk of peptic ulcer disease in the
taiwanese population. Front Pharmacol. 8:2102017. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Wang T, Seah S, Loh X, Chan CW, Hartman M,
Goh BC and Lee SC: Simvastatin-induced breast cancer cell death and
deactivation of PI3K/Akt and MAPK/ERK signalling are reversed by
metabolic products of the mevalonate pathway. Oncotarget.
7:2532–2544. 2016.PubMed/NCBI
|
|
36
|
Istvan ES and Deisenhofer J: Structural
mechanism for statin inhibition of HMG-CoA reductase. Science.
292:1160–1164. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Niesor EJ, Schwartz GG, Perez A, Stauffer
A, Durrwell A, Bucklar-Suchan G, Benghozi R, Abt M and Kallend D:
Statin-induced decrease in ATP-binding cassette transporter A1
expression via microRNA33 induction may counteract cholesterol
efflux to high-density lipoprotein. Cardiovasc Drugs Ther. 29:7–14.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Sone H, Shimano H, Shu M, Nakakuki M,
Takahashi A, Sakai M, Sakamoto Y, Yokoo T, Matsuzaka K, Okazaki H,
et al: Statins downregulate ATP-binding-cassette transporter A1
gene expression in macrophages. Biochem Biophys Res Commun.
316:790–794. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Wong J, Quinn CM, Gelissen IC, Jessup W
and Brown AJ: The effect of statins on ABCA1 and ABCG1 expression
in human macrophages is influenced by cellular cholesterol levels
and extent of differentiation. Atherosclerosis. 196:180–189. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Ando H, Tsuruoka S, Yamamoto H, Takamura
T, Kaneko S and Fujimura A: Effects of pravastatin on the
expression of ATP-binding cassette transporter A1. J Pharmacol Exp
Ther. 311:420–425. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Ogunwobi OO and Beales IL: Statins inhibit
proliferation and induce apoptosis in Barrett's esophageal
adenocarcinoma cells. Am J Gastroenterol. 103:825–837. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Nonaka M, Uota S, Saitoh Y, Takahashi M,
Sugimoto H, Amet T, Arai A, Miura O, Yamamoto N and Yamaoka S: Role
for protein geranylgeranylation in adult T-cell leukemia cell
survival. Exp Cell Res. 315:141–150. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Neufeld EB, Stonik JA, Demosky SJ Jr,
Knapper CL, Combs CA, Cooney A, Comly M, Dwyer N, Blanchette-Mackie
J, Remaley AT, et al: The ABCA1 transporter modulates late
endocytic trafficking: Insights from the correction of the genetic
defect in Tangier disease. J Biol Chem. 279:15571–15578. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Neufeld EB, O'Brien K, Walts AD, Stonik
JA, Malide D, Combs CA and Remaley AT: The human ABCG1 transporter
mobilizes plasma membrane and late endosomal
non-sphingomyelin-associated-cholesterol for efflux and
esterification. Biology (Basel). 3:866–891. 2014.PubMed/NCBI
|
|
45
|
Wang J, Mitsche MA, Lütjohann D, Cohen JC,
Xie XS and Hobbs HH: Relative roles of ABCG5/ABCG8 in liver and
intestine. J Lipid Res. 56:319–330. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Ramirez CM, Davalos A, Goedeke L, Salerno
AG, Warrier N, Cirera-Salinas D, Suárez Y and Fernández-Hernando C:
MicroRNA-758 regulates cholesterol efflux through
posttranscriptional repression of ATP-binding cassette transporter
A1. Arterioscler Thromb Vas Biol. 31:2707–2714. 2011. View Article : Google Scholar
|
|
47
|
Genvigir FD, Rodrigues AC, Cerda A, Hirata
MH, Curi R and Hirata RD: ABCA1 and ABCG1 expressions are regulated
by statins and ezetimibe in Caco-2 cells. Drug Metab Drug Interact.
26:33–36. 2011. View Article : Google Scholar
|
|
48
|
Janowski BA, Willy PJ, Devi TR, Falck JR
and Mangelsdorf DJ: An oxysterol signalling pathway mediated by the
nuclear receptor LXR alpha. Nature. 383:728–731. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Beyea MM, Heslop CL, Sawyez CG, Edwards
JY, Markle JG, Hegele RA and Huff MW: Selective up-regulation of
LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through
increased endogenous synthesis of 24(S),25-epoxycholesterol. J Biol
Chem. 282:5207–5216. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Wilson JM, Kunnimalaiyaan S,
Kunnimalaiyaan M and Gamblin TC: Inhibition of the AKT pathway in
cholangiocarcinoma by MK2206 reduces cellular viability via
induction of apoptosis. Cancer Cell Int. 15:132015. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Mistafa O and Stenius U: Statins inhibit
Akt/PKB signaling via P2X7 receptor in pancreatic cancer cells.
Biochem Pharmacol. 78:1115–1126. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Miraglia E, Högberg J and Stenius U:
Statins exhibit anticancer effects through modifications of the
pAkt signaling pathway. Int J Oncol. 40:867–875. 2012.PubMed/NCBI
|
