|
1
|
Fessler E and Medema JP: Colorectal cancer
subtypes: Developmental origin and microenvironmental regulation.
Trends Cancer. 2:505–518. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Takayama T, Ohi M, Hayashi T, Miyanishi K,
Nobuoka A, Nakajima T, Satoh T, Takimoto R, Kato J, Sakamaki S and
Niitsu Y: Analysis of K-ras, APC, and beta-catenin in aberrant
crypt foci in sporadic adenoma, cancer, and familial adenomatous
polyposis. Gastroenterology. 121:599–611. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
IJspeert JE, Vermeulen L, Meijer GA and
Dekker E: Serrated neoplasia-role in colorectal carcinogenesis and
clinical implications. Nat Rev Gastroenterol Hepatol. 12:401–409.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Bray F, Ferlay J, Soerjomataram I, Siegel
RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN
estimates of incidence and mortality worldwide for 36 cancers in
185 countries. CA Cancer J Clin. 68:394–424. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Labianca R, Beretta GD, Kildani B, Milesi
L, Merlin F, Mosconi S, Pessi MA, Prochilo T, Quadri A, Gatta G, et
al: Colon cancer. Crit Rev Oncol Hematol. 74:106–133. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Fedirko V, Tramacere I, Bagnardi V, Rota
M, Scotti L, Islami F, Negri E, Straif K, Romieu I, La Vecchia C,
et al: Alcohol drinking and colorectal cancer risk: An overall and
dose-response meta-analysis of published studies. Ann Oncol.
22:1958–1972. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Campbell PT, Cotterchio M, Dicks E,
Parfrey P, Gallinger S and McLaughlin JR: Excess body weight and
colorectal cancer risk in Canada: Associations in subgroups of
clinically defined familial risk of cancer. Cancer Epidemiol
Biomarkers Prev. 16:1735–1744. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Kuipers EJ, Grady WM, Lieberman D,
Seufferlein T, Sung JJ, Boelens PG, van de Velde CJ and Watanabe T:
Colorectal cancer. Nat Rev Dis Primers. 1:150652015. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Darlison MG, Pahal I and Thode C:
Consequences of the evolution of the GABA(A) receptor gene family.
Cell Mol Neurobiol. 25:607–624. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Mele M, Ferreira PG, Reverter F, DeLuca
DS, Monlong J, Sammeth M, Young TR, Goldmann JM, Pervouchine DD,
Sullivan TJ, et al: Human genomics. The human transcriptome across
tissues and individuals. Science. 348:660–665. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Tian J, Lu Y, Zhang H, Chau CH, Dang HN
and Kaufman DL: Gamma-aminobutyric acid inhibits T cell
autoimmunity and the development of inflammatory responses in a
mouse type 1 diabetes model. J Immunol. 173:5298–5304. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Macdonald RL and Olsen RW: GABAA receptor
channels. Annu Rev Neurosci. 17:569–602. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Neelands TR and Macdonald RL:
Incorporation of the pi subunit into functional gamma-aminobutyric
Acid(A) receptors. Mol Pharmacol. 56:598–610. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Gross AM, Kreisberg JF and Ideker T:
Analysis of matched tumor and normal profiles reveals common
transcriptional and epigenetic signals shared across cancer types.
PLoS One. 10:e01426182015. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Robinson MD, McCarthy DJ and Smyth GK:
EdgeR: A bioconductor package for differential expression analysis
of digital gene expression data. Bioinformatics. 26:139–140. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Mounir M, Lucchetta M, Silva TC, Olsen C,
Bontempi G, Chen X, Noushmehr H, Colaprico A and Papaleo E: New
functionalities in the TCGAbiolinks package for the study and
integration of cancer data from GDC and GTEx. PLoS Comput Biol.
15:e10067012019. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Huang da W, Sherman BT and Lempicki RA:
Bioinformatics enrichment tools: Paths toward the comprehensive
functional analysis of large gene lists. Nucleic Acids Res.
37:1–13. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Huang da W, Sherman BT and Lempicki RA:
Systematic and integrative analysis of large gene lists using DAVID
bioinformatics resources. Nat Protoc. 4:44–57. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Maere S, Heymans K and Kuiper M: BiNGO: A
cytoscape plugin to assess overrepresentation of gene ontology
categories in biological networks. Bioinformatics. 21:3448–3449.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Warde-Farley D, Donaldson SL, Comes O,
Zuberi K, Badrawi R, Chao P, Franz M, Grouios C, Kazi F, Lopes CT,
et al: The GeneMANIA prediction server: Biological network
integration for gene prioritization and predicting gene function.
Nucleic Acids Res 38 (Web Server Issue). W214–W220. 2010.
View Article : Google Scholar
|
|
21
|
Montojo J, Zuberi K, Rodriguez H, Kazi F,
Wright G, Donaldson SL, Morris Q and Bader GD: GeneMANIA cytoscape
plugin: Fast gene function predictions on the desktop.
Bioinformatics. 26:2927–2928. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Szklarczyk D, Franceschini A, Wyder S,
Forslund K, Heller D, Huerta-Cepas J, Simonovic M, Roth A, Santos
A, Tsafou KP, et al: STRING v10: Protein-protein interaction
networks, integrated over the tree of life. Nucleic Acids Res 43
(Database Issue). D447–D452. 2015. View Article : Google Scholar
|
|
23
|
Shaul YD, Yuan B, Thiru P, Nutter-Upham A,
McCallum S, Lanzkron C, Bell GW and Sabatini DM: MERAV: A tool for
comparing gene expression across human tissues and cell types.
Nucleic Acids Res. 44(D1): D560–D566. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Tang Z, Li C, Kang B, Gao G, Li C and
Zhang Z: GEPIA: A web server for cancer and normal gene expression
profiling and interactive analyses. Nucleic Acids Res 45 (W1).
W98–W102. 2017. View Article : Google Scholar
|
|
25
|
Liao X, Han C, Wang X, et al: Prognostic
value of minichromosome maintenance mRNA expression in early-stage
pancreatic ductal adenocarcinoma patients after
pancreaticoduodenectomy. Cancer Manag Res. 10:3255–3271. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Tu HP, Ko AM, Chiang SL, Lee SS, Lai HM,
Chung CM, Huang CM, Lee CH, Kuo TM, Hsieh MJ and Ko YC: Joint
effects of alcohol consumption and ABCG2 Q141K on chronic
tophaceous gout risk. J Rheumatol. 41:749–758. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Balachandran VP, Gonen M, Smith JJ and
DeMatteo RP: Nomograms in oncology: More than meets the eye. Lancet
Oncol. 16:e173–e180. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Subramanian A, Tamayo P, Mootha VK,
Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub
TR, Lander ES and Mesirov JP: Gene set enrichment analysis: A
knowledge-based approach for interpreting genome-wide expression
profiles. Proc Natl Acad Sci USA. 102:15545–15550. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Nayeem N, Green TP, Martin IL and Barnard
EA: Quaternary structure of the native GABAA receptor determined by
electron microscopic image analysis. J Neurochem. 62:815–818. 1994.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Gumireddy K, Li A, Kossenkov AV, Sakurai
M, Yan J, Li Y, Xu H, Wang J, Zhang PJ, Zhang L, et al: The
mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt
activation and breast cancer metastasis. Nat Commun. 7:107152016.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Bautista W, Perez-Alvarez V, Burczynski F,
Raouf A, Klonisch T and Minuk G: Membrane potential differences and
GABAA receptor expression in hepatic tumor and non-tumor stem
cells. Can J Physiol Pharmacol. 92:85–91. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Hackett CS, Quigley DA, Wong RA, Chen J,
Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, et
al: Expression quantitative trait loci and receptor pharmacology
implicate Arg1 and the GABA-A receptor as therapeutic targets in
neuroblastoma. Cell Rep. 9:1034–1046. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Chen ZA, Bao MY, Xu YF, Zha RP, Shi HB,
Chen TY and He XH: Suppression of Human liver cancer cell migration
and invasion via the GABAA receptor. Cancer Biol Med. 9:90–98.
2012.PubMed/NCBI
|
|
34
|
Minuk GY, Zhang M, Gong Y, Minuk L, Dienes
H, Pettigrew N, Kew M, Lipschitz J and Sun D: Decreased hepatocyte
membrane potential differences and GABAa-beta3 expression in human
hepatocellular carcinoma. Hepatology. 45:735–745. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Takehara A, Hosokawa M, Eguchi H, Ohigashi
H, Ishikawa O, Nakamura Y and Nakagawa H: Gamma-aminobutyric acid
(GABA) stimulates pancreatic cancer growth through overexpressing
GABAA receptor pi subunit. Cancer Res. 67:9704–9712. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Zhang YA, Liu HN, Zhu JM, Zhang DY, Shen
XZ and Liu TT: RNA binding protein Nova1 promotes tumor growth in
vivo and its potential mechanism as an oncogene may due to its
interaction with GABAA Receptor-ү2. J Biomed Sci.
23:712016. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Okegawa T, Pong RC, Li Y and Hsieh JT: The
role of cell adhesion molecule in cancer progression and its
application in cancer therapy. Acta Biochim Pol. 51:445–457. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Kawauchi T: Cell adhesion and its
endocytic regulation in cell migration during neural development
and cancer metastasis. Int J Mol Sci. 13:4564–4590. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Desgrosellier JS and Cheresh DA: Integrins
in cancer: Biological implications and therapeutic opportunities.
Nat Rev Cancer. 10:9–22. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Mouw JK, Yui Y, Damiano L, Bainer RO,
Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM, et
al: Tissue mechanics modulate microRNA-dependent PTEN expression to
regulate malignant progression. Nat Med. 20:360–367. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Kimura C, Hayashi M, Mizuno Y and Oike M:
Endothelium-dependent epithelial-mesenchymal transition of tumor
cells: Exclusive roles of transforming growth factor β1 and β2.
Biochim Biophys Acta. 1830:4470–4481. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Ghesquiere B, Wong BW, Kuchnio A and
Carmeliet P: Metabolism of stromal and immune cells in health and
disease. Nature. 511:167–176. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Lee E, Pandey NB and Popel AS: Crosstalk
between cancer cells and blood endothelial and lymphatic
endothelial cells in tumour and organ microenvironment. Expert Rev
Mol Med. 17:e32015. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Hanahan D and Weinberg RA: Hallmarks of
cancer: The next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Park SH, Kim BR, Lee JH, Park ST, Lee SH,
Dong SM and Rho SB: GABARBP down-regulates HIF-1α expression
through the VEGFR-2 and PI3K/mTOR/4E-BP1 pathways. Cell Signal.
26:1506–1513. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Ohsumi Y: Molecular dissection of
autophagy: Two ubiquitin-like systems. Nat Rev Mol Cell Biol.
2:211–216. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Mizushima N: The pleiotropic role of
autophagy: From protein metabolism to bactericide. Cell Death
Differ. 12 (Suppl 2):S1535–S1541. 2005. View Article : Google Scholar
|
|
48
|
Zhu JH, Horbinski C, Guo F, Watkins S,
Uchiyama Y and Chu CT: Regulation of autophagy by extracellular
signal-regulated protein kinases during
1-methyl-4-phenylpyridinium-induced cell death. Am J Pathol.
170:75–86. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Mizumoto S, Yamada S and Sugahara K:
Molecular interactions between chondroitin-dermatan sulfate and
growth factors/receptors/matrix proteins. Curr Opin Struct Biol.
34:35–42. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Willis CM and Kluppel M: Chondroitin
sulfate-E is a negative regulator of a pro-tumorigenic
Wnt/beta-catenin-Collagen 1 axis in breast cancer cells. PLoS One.
9:e1039662014. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Ludvigsson JF, Neovius M, Ye W and
Hammarstrom L: IgA deficiency and risk of cancer: A
population-based matched cohort study. J Clin Immunol. 35:182–188.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Malmberg KJ, Carlsten M, Bjorklund A,
Sohlberg E, Bryceson YT and Ljunggren HG: Natural killer
cell-mediated immunosurveillance of human cancer. Semin Immunol.
31:20–29. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Hannun YA and Obeid LM: Principles of
bioactive lipid signalling: Lessons from sphingolipids. Nat Rev Mol
Cell Biol. 9:139–150. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Ogretmen B: Sphingolipid metabolism in
cancer signalling and therapy. Nat Rev Cancer. 18:33–50. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Sarathi A and Palaniappan A: Novel
significant stage-specific differentially expressed genes in
hepatocellular carcinoma. BMC Cancer. 19:6632019. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Zafrakas M, Chorovicer M, Klaman I,
Kristiansen G, Wild PJ, Heindrichs U, Knüchel R and Dahl E:
Systematic characterisation of GABRP expression in sporadic breast
cancer and normal breast tissue. Int J Cancer. 118:1453–1459. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Symmans WF, Fiterman DJ, Anderson SK,
Ayers M, Rouzier R, Dunmire V, Stec J, Valero V, Sneige N,
Albarracin C, et al: A single-gene biomarker identifies breast
cancers associated with immature cell type and short duration of
prior breastfeeding. Endocr Relat Cancer. 12:1059–1069. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Sung HY, Yang SD, Ju W and Ahn JH:
Aberrant epigenetic regulation of GABRP associates with aggressive
phenotype of ovarian cancer. Exp Mol Med. 49:e3352017. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Jiang SH, Zhu LL, Zhang M, Li RK, Yang Q,
Yan JY, Zhang C, Yang JY, Dong FY, Dai M, et al: GABRP regulates
chemokine signalling, macrophage recruitment and tumour progression
in pancreatic cancer through tuning KCNN4-mediated Ca2+
signalling in a GABA-independent manner. Gut. 68:1994–2006. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Li YH, Liu Y, Li YD, Liu YH, Li F, Ju Q,
Xie PL and Li GCl: GABA stimulates human hepatocellular carcinoma
growth through overexpressed GABAA receptor theta subunit. World J
Gastroenterol. 18:2704–2711. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Engelman JA: Targeting PI3K signalling in
cancer: Opportunities, challenges and limitations. Nat Rev Cancer.
9:550–562. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Yu H, Lee H, Herrmann A, Buettner R and
Jove R: Revisiting STAT3 signalling in cancer: New and unexpected
biological functions. Nat Rev Cancer. 14:736–746. 2014. View Article : Google Scholar : PubMed/NCBI
|
