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Article Open Access

Diagnostic value and imaging features of multi-detector CT in lung adenocarcinoma with ground glass nodule patients

  • Authors:
    • Jun Lu
    • Haitao Tang
    • Xinguo Yang
    • Lei Liu
    • Minxia Pang
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Shengli Oilfield Central Hospital, Dongying, Shandong 257034, P.R. China, Department of Surgery, Shengli Oilfield Central Hospital, Dongying, Shandong 257034, P.R. China
    Copyright: © Lu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 693-698
    |
    Published online on: May 15, 2020
       https://doi.org/10.3892/ol.2020.11631
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Abstract

This study investigated the application value and imaging features of multi-detector CT (MDCT) in the treatment of lung adenocarcinoma with ground glass nodules (GGN). The medical data of 168 patients with pulmonary GGN in Shengli Oilfield Central Hospital from January 2013 to June 2015 were analyzed. Patients with microinvasive adenocarcinoma and invasive adenocarcinoma were included in group A (invasive lung adenocarcinoma, n=98), while patients with atypical adenomatous hyperplasia and adenocarcinoma in situ were included in group B (pre-invasive lung adenocarcinoma, n=70). The imaging features of MDCT were compared. ROC curves of the size of nidus and the size of solid component were drawn for the diagnosis of invasive lung adenocarcinoma. Logistic multivariate regression analysis was used to analyze the risk factors that affected invasive lung adenocarcinoma. There were significant differences in nidus, burr, and lobes of the patients between groups A and B. The size of nidus and the size of solid component of the patients in group A were significantly higher than those of the patients in group B. The AUCs of the size of the nidus and the size of the solid component of the invasive lung adenocarcinoma were 0.891 and 0.902, respectively. The AUC of the combined diagnosis was 0.984. Size of the nidus, size of the solid component, nature of the lesion, burr, and lobes were all risk factors for invasive lung adenocarcinoma. In patients with GGN, size of the nidus and size of the solid component can be used as excellent diagnostic parameters for invasive lung adenocarcinoma, and nidus size (≥9.8 mm), size of the solid component (≥0.9 mm), the mixed GGN nature of the nidus, burr and lobes can distinguish invasive lung adenocarcinoma and pre-invasive lesions.
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Copy and paste a formatted citation
Spandidos Publications style
Lu J, Tang H, Yang X, Liu L and Pang M: Diagnostic value and imaging features of multi-detector CT in lung adenocarcinoma with ground glass nodule patients. Oncol Lett 20: 693-698, 2020.
APA
Lu, J., Tang, H., Yang, X., Liu, L., & Pang, M. (2020). Diagnostic value and imaging features of multi-detector CT in lung adenocarcinoma with ground glass nodule patients. Oncology Letters, 20, 693-698. https://doi.org/10.3892/ol.2020.11631
MLA
Lu, J., Tang, H., Yang, X., Liu, L., Pang, M."Diagnostic value and imaging features of multi-detector CT in lung adenocarcinoma with ground glass nodule patients". Oncology Letters 20.1 (2020): 693-698.
Chicago
Lu, J., Tang, H., Yang, X., Liu, L., Pang, M."Diagnostic value and imaging features of multi-detector CT in lung adenocarcinoma with ground glass nodule patients". Oncology Letters 20, no. 1 (2020): 693-698. https://doi.org/10.3892/ol.2020.11631
Copy and paste a formatted citation
x
Spandidos Publications style
Lu J, Tang H, Yang X, Liu L and Pang M: Diagnostic value and imaging features of multi-detector CT in lung adenocarcinoma with ground glass nodule patients. Oncol Lett 20: 693-698, 2020.
APA
Lu, J., Tang, H., Yang, X., Liu, L., & Pang, M. (2020). Diagnostic value and imaging features of multi-detector CT in lung adenocarcinoma with ground glass nodule patients. Oncology Letters, 20, 693-698. https://doi.org/10.3892/ol.2020.11631
MLA
Lu, J., Tang, H., Yang, X., Liu, L., Pang, M."Diagnostic value and imaging features of multi-detector CT in lung adenocarcinoma with ground glass nodule patients". Oncology Letters 20.1 (2020): 693-698.
Chicago
Lu, J., Tang, H., Yang, X., Liu, L., Pang, M."Diagnostic value and imaging features of multi-detector CT in lung adenocarcinoma with ground glass nodule patients". Oncology Letters 20, no. 1 (2020): 693-698. https://doi.org/10.3892/ol.2020.11631
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