|
1
|
Ostrom QT, Gittleman H, Truitt G, Boscia
A, Kruchko C and Barnholtz-Sloan JS: CBTRUS statistical report:
Primary brain and other central nervous system tumors diagnosed in
the United States in 2011–2015. Neuro Oncol. 20 (Suppl 4):iv1–iv86.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lapointe S, Perry A and Butowski NA:
Primary brain tumours in adults. Lancet. 392:432–446. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ostrom QT, Cote DJ, Ascha M, Kruchko C and
Barnholtz- Sloan JS: Adult glioma incidence and survival by race or
ethnicity in the United States from 2000 to 2014. JAMA Oncol.
4:1254–1262. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Hartmann C, Hentschel B, Wick Wm, Capper
D, Felsberg J, Simon M, Westphal M, Schackert G, Meyermann R,
Pietsch T, et al: Patients with IDH1 wild type anaplastic
astrocytomas exhibit worse prognosis than IDH1-mutated
glioblastomas, and IDH1 mutation status accounts for the
unfavorable prognostic effect of higher age: Implications for
classification of gliomas. Acta Neuropathol. 120:707–718. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Metellus P, Coulibaly B, Colin C, de Paula
AM, Vasiljevic A, Taieb D, Barlier A, Boisselier B, Mokhtari K,
Wang XW, et al: Absence of IDH mutation identifies a novel
radiologic and molecular subtype of WHO grade II gliomas with
dismal prognosis. Acta Neuropathol. 120:719–729. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Frattini V, Trifonov V, Chan JM, Castano
A, Lia M, Abate F, Keir ST, Ji AX, Zoppoli P, Niola F, et al: The
integrated landscape of driver genomic alterations in glioblastoma.
Nat Genet. 45:1141–1149. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
7
|
Ceccarelli M, Barthel FP, Malta TM,
Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh
A, Pagnotta SM, et al: Molecular profiling reveals biologically
discrete subsets and pathways of progression in diffuse glioma.
Cell. 164:550–563. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Weterman MA, Ajubi N, van Dinter IM, Degen
WG, van Muijen GN, Ruitter DJ and Bloemers HP: nmb, a novel gene,
is expressed in low-metastatic human melanoma cell lines and
xenografts. Int J Cancer. 60:73–81. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Zhuo H and Zhou L: Gpnmb/osteoactivin: An
indicator and therapeutic target in tumor and nontumorous lesions.
Pharmazie. 71:555–561. 2016.PubMed/NCBI
|
|
10
|
Maric G, Annis MG, Dong Z, Rose AA, Ng S,
Perkins D, MacDonald PA, Ouellet V, Russo C and Siegel PM: GPNMB
cooperates with neuropilin-1 to promote mammary tumor growth and
engages integrin α5β1 for efficient breast cancer metastasis.
Oncogene. 34:5494–5504. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Li Y, Yuan S, Liu J, Wang Y, Zhang Y, Chen
X and Si W: CSE1L silence inhibits the growth and metastasis in
gastric cancer by repressing GPNMB via positively regulating
transcription factor MITF. J Cell Physiol. 235:2071–2079. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Torres C, Linares A, Alejandre MJ,
Palomino-Morales R, Martin M, Delgado JR, Martinez J and Perales S:
The potential role of the glycoprotein osteoactivin/glycoprotein
nonmetastatic melanoma protein B in pancreatic cancer. Pancreas.
44:302–310. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Taya M and Hammes SR: Glycoprotein
non-metastatic melanoma protein B (GPNMB) and cancer: A novel
potential therapeutic target. Steroids. 133:102–107. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Hoashi T, Sato S, Yamaguchi Y, Passeron T,
Tamaki K and Hearing VJ: Glycoprotein nonmetastatic melanoma
protein B, a melanocytic cell marker, is a melanosome-specific and
proteolytically released protein. FASEB J. 24:1616–1629. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Abdelmagid SM, Barbe MF, Rico MC,
Salihoglu S, Arango-Hisijara I, Selim AH, Anderson MG, Owen TA,
Popoff SN and Safadi FF: Osteoactivin, an anabolic factor that
regulates osteoblast differentiation and function. Exp Cell Res.
314:2334–2351. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Tomihari M, Hwang SH, Chung JS, Cruz PD Jr
and Ariizumi K: Gpnmb is a melanosome-associated glycoprotein that
contributes to melanocyte/keratinocyte adhesion in a RGD-dependent
fashion. Exp Dermatol. 18:586–595. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Ripoll VM, Meadows NA, Raggatt LJ, Chang
MK, Pettit AR, Cassady AI and Hume DA: Microphthalmia transcription
factor regulates the expression of the novel osteoclast factor
GPNMB. Gene. 413:32–41. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Sheng MH, Wergedal JE, Mohan S and Lau KH:
Osteoactivin is a novel osteoclastic protein and plays a key role
in osteoclast differentiation and activity. FEBS Lett.
582:1451–1458. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ripoll VM, Irvine KM, Ravasi T, Sweet MJ
and Hume DA: Gpnmb is induced in macrophages by IFN-gamma and
lipopolysaccharide and acts as a feedback regulator of
proinflammatory responses. J Immunol. 178:6557–6566. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Ahn JH, Lee Y, Jeon C, Lee SJ, Lee BH,
Choi KD and Bae YS: Identification of the genes differentially
expressed in human dendritic cell subsets by cDNA subtraction and
microarray analysis. Blood. 100:1742–1754. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Chen C, Okita Y, Watanabe Y, Abe F, Fikry
MA, Ichikawa Y, Suzuki H, Shibuya A and Kato M: Glycoprotein nmb is
exposed on the surface of dormant breast cancer cells and induces
stem cell-like properties. Cancer Res. 78:6424–6435.
2018.PubMed/NCBI
|
|
22
|
Oyewumi MO, Manickavasagam D, Novak K,
Wehrung D, Paulic N, Moussa FM, Sondag GR and Safadi FF:
Osteoactivin (GPNMB) ectodomain protein promotes growth and
invasive behavior of human lung cancer cells. Oncotarget.
7:13932–13944. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kuan CT, Wakiya K, Dowell JM, Herndon JE
II, Reardon DA, Graner MW, Riggins GJ, Wikstrand CJ and Bigner DD:
Glycoprotein nonmetastatic melanoma protein B, a potential
molecular therapeutic target in patients with glioblastoma
multiforme. Clin Cancer Res. 12:1970–1982. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Ono Y, Chiba S, Yano H, Nakayama N, Saio
M, Tsuruma K, Shimazawa M, Iwama T and Hara H: Glycoprotein
nonmetastatic melanoma protein B (GPNMB) promotes the progression
of brain glioblastoma via Na+/K+-ATPase.
Biochem Biophys Res Commun. 481:7–12. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Bao G, Wang N, Li R, Xu G, Liu P and He B:
Glycoprotein non-metastaticmelanoma protein B promotes glioma
motility and angiogenesis through the Wnt/β-catenin signaling
pathway. Exp Biol Med (Maywood). 241:1968–1976. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Reifenberger G, Weber RG, Riehmer V,
Kaulich K, Willscher E, Wirth H, Gietzelt J, Hentschel B, Westphal
M, Simon M, et al: Molecular characterization of long-term
survivors of glioblastoma using genome- and transcriptome-wide
profiling. Int J Cancer. 135:1822–1831. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Yan W, Zhang W, You G, Zhang J, Han L, Bao
Z, Wang Y, Liu Y, Jiang C, Kang C, et al: Molecular classification
of gliomas based on whole genome gene expression: A systematic
report of 225 samples from the Chinese glioma cooperative group.
Neuro Oncol. 14:1432–1440. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
R Core Team, . R: A language and
environment for statistical computing. R Foundation for Statistical
Computing. (Vienna, Austria). URL http://www.R-project.org/.
2014.
|
|
29
|
Wettenhall JM and Smyth GK: limmaGUI: A
graphical user interface for linear modeling of microarray data.
Bioinformatics. 20:3705–3706. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Yu G, Wang LG, Han Y and He QY:
clusterProfiler: An R package for comparing biological themes among
gene clusters. OMICS. 16:284–287. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Luo W and Brouwer C: Pathview: An
R/Bioconductor package for pathway-based data integration and
visualization. Bioinformatics. 29:1830–1831. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Verhaak RG, Hoadley KA, Purdom E, Wang V,
Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, et al:
Integrated genomic analysis identifies clinically relevant subtypes
of glioblastoma characterized by abnormalities in PDGFRA, IDH1,
EGFR, and NF1. Cancer Cell. 17:98–110. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Hofer S and Lassman AB: Molecular markers
in gliomas: Impact for the clinician. Target Oncol. 5:201–210.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Ma R, de Pennington N, Hofer M, Blesing C
and Stacey R: Diagnostic and prognostic markers in gliomas-an
update. Br J Neurosurg. 27:311–315. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Thomas L, Di Stefano AL and Ducray F:
Predictive biomarkers in adult gliomas: The present and the future.
Curr Opin Oncol. 25:689–694. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Ellison DW: Multiple molecular data sets
and the classification of adult diffuse gliomas. N Engl J Med.
372:2555–2557. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Gimona M and Buccione R: Adhesions that
mediate invasion. Int J Biochem Cell Biol. 38:1875–1892. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Yamaguchi H, Wyckoff J and Condeelis J:
Cell migration in tumors. Curr Opin Cell Biol. 17:559–564. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Kedrin D, van Rheenen J, Hernandez L,
Condeelis J and Segall JE: Cell motility and cytoskeletal
regulation in invasion and metastasis. J Mammary Gland Biol
Neoplasia. 12:143–152. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Staff AC: An introduction to cell
migration and invasion. Scand J Clin Lab Invest. 61:257–268. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Sciumè G, Santoni A and Bernardini G:
Chemokines and glioma: Invasion and more. J Neuroimmunol. 224:8–12.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Wick W, Naumann U and Weller M:
Transforming growth factor-beta: A molecular target for the future
therapy of glioblastoma. Curr Pharm Des. 12:341–349. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Wells A, Grahovac J, Wheeler S, Ma B and
Lauffenburger D: Targeting tumor cell motility as a strategy
against invasion and metastasis. Trends Pharmacol Sci. 34:283–289.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Laufs S, Schumacher J and Allgayer H:
Urokinase-receptor (u-PAR): An essential player in multiple games
of cancer: A review on its role in tumor progression, invasion,
metastasis, proliferation/dormancy, clinical outcome and minimal
residual disease. Cell Cycle. 5:1760–1771. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Kessenbrock K, Plaks V and Werb Z: Matrix
metalloproteinases: Regulators of the tumor microenvironment. Cell.
141:52–67. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Kassis J, Lauffenburger DA, Turner T and
Wells A: Tumor invasion as dysregulated cell motility. Semin Cancer
Biol. 11:105–117. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Jiang WG, Sanders AJ, Katoh M, Ungefroren
H, Gieseler F, Prince M, Thompson SK, Zollo M, Spano D, Dhawan P,
et al: Tissue invasion and metastasis: Molecular, biological and
clinical perspectives. Semin Cancer Biol. 35 (Suppl):S244–S275.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Jakowlew SB: Transforming growth
factor-beta in cancer and metastasis. Cancer Metastasis Rev.
25:435–457. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Friedl P and Wolf K: Tumour-cell invasion
and migration: Diversity and escape mechanisms. Nat Rev Cancer.
3:362–374. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Andreasen PA, Kjøller L, Christensen L and
Duffy MJ: The urokinase-type plasminogen activator system in cancer
metastasis: A review. Int J Cancer. 72:1–22. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Westermarck J and Kähäri VM: Regulation of
matrix metalloproteinase expression in tumor invasion. FASEB J.
13:781–792. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Jain RK, di Tomaso E, Duda DG, Loeffler
JS, Sorensen AG and Batchelor TT: Angiogenesis in brain tumours.
Nat Rev Neurosci. 8:610–622. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Anderson SA, Glod J, Arbab AS, Noel M,
Ashari P, Fine HA and Frank JA: Noninvasive MR imaging of
magnetically labeled stem cells to directly identify neovasculature
in a glioma model. Blood. 105:420–425. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Smith SJ, Tilly H, Ward JH, Macarthur DC,
Lowe J, Coyle B and Grundy RG: CD105 (Endoglin) exerts prognostic
effects via its role in the microvascular niche of paediatric high
grade glioma. Acta Neuropathol. 124:99–110. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Hudson AL, Parker NR, Khong P, Parkinson
JF, Dwight T, Ikin RJ, Zhu Y, Chen J, Wheeler HR and Howell VM:
Glioblastoma Recurrence correlates with increased APE1 and
polarization toward an immuno-suppressive microenvironment. Front
Oncol. 8:3142018. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Walentynowicz KA, Ochocka N, Pasierbinska
M, Wojnicki K, Stepniak K, Mieczkowski J, Ciechomska IA and
Kaminska B: In search for reliable markers of glioma-induced
polarization of microglia. Front Immunol. 9:13292018. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Sun X, Liu X, Xia M, Shao Y and Zhang XD:
Multicellular gene network analysis identifies a macrophage-related
gene signature predictive of therapeutic response and prognosis of
gliomas. J Transl Med. 17:1592019. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Zhou W, Ke SQ, Huang Z, Flavahan W, Fang
X, Paul J, Wu L, Sloan AE, McLendon RE, Li X, et al: Periostin
secreted by glioblastoma stem cells recruits M2 tumour-associated
macrophages and promotes malignant growth. Nat Cell Biol.
17:170–182. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Hambardzumyan D, Gutmann DH and Kettenmann
H: The role of microglia and macrophages in glioma maintenance and
progression. Nat Neurosci. 19:20–27. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Mantovani A, Sozzani S, Locati M, Allavena
P and Sica A: Macrophage polarization: Tumor-associated macrophages
as a paradigm for polarized M2 mononuclear phagocytes. Trends
Immunol. 23:549–555. 2002. View Article : Google Scholar : PubMed/NCBI
|
